全文获取类型
收费全文 | 120031篇 |
免费 | 7415篇 |
国内免费 | 673篇 |
专业分类
耳鼻咽喉 | 1137篇 |
儿科学 | 3966篇 |
妇产科学 | 2782篇 |
基础医学 | 17540篇 |
口腔科学 | 4357篇 |
临床医学 | 11449篇 |
内科学 | 26308篇 |
皮肤病学 | 2942篇 |
神经病学 | 11999篇 |
特种医学 | 2790篇 |
外国民族医学 | 1篇 |
外科学 | 10945篇 |
综合类 | 515篇 |
一般理论 | 66篇 |
预防医学 | 12065篇 |
眼科学 | 1963篇 |
药学 | 8411篇 |
中国医学 | 473篇 |
肿瘤学 | 8410篇 |
出版年
2024年 | 98篇 |
2023年 | 1088篇 |
2022年 | 1032篇 |
2021年 | 4152篇 |
2020年 | 2563篇 |
2019年 | 3519篇 |
2018年 | 3977篇 |
2017年 | 2986篇 |
2016年 | 3454篇 |
2015年 | 3862篇 |
2014年 | 5094篇 |
2013年 | 6678篇 |
2012年 | 10162篇 |
2011年 | 10543篇 |
2010年 | 5681篇 |
2009年 | 4833篇 |
2008年 | 8333篇 |
2007年 | 8325篇 |
2006年 | 7651篇 |
2005年 | 7156篇 |
2004年 | 6471篇 |
2003年 | 5765篇 |
2002年 | 5233篇 |
2001年 | 709篇 |
2000年 | 497篇 |
1999年 | 719篇 |
1998年 | 943篇 |
1997年 | 773篇 |
1996年 | 642篇 |
1995年 | 530篇 |
1994年 | 511篇 |
1993年 | 422篇 |
1992年 | 362篇 |
1991年 | 260篇 |
1990年 | 240篇 |
1989年 | 234篇 |
1988年 | 226篇 |
1987年 | 190篇 |
1986年 | 208篇 |
1985年 | 153篇 |
1984年 | 183篇 |
1983年 | 184篇 |
1982年 | 215篇 |
1981年 | 163篇 |
1980年 | 166篇 |
1979年 | 104篇 |
1978年 | 97篇 |
1977年 | 81篇 |
1976年 | 73篇 |
1974年 | 73篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
11.
Jose M. Morales Jose Angel Martinez-Flores Manuel Serrano Maria José Castro Francisco Javier Alfaro Florencio García Miguel Angel Martínez Amado Andrés Esther González Manuel Praga Estela Paz-Artal Antonio Serrano 《Journal of the American Society of Nephrology : JASN》2015,26(3):735-745
In the current immunosuppressive therapy era, vessel thrombosis is the most common cause of early graft loss after renal transplantation. The prevalence of IgA anti–β2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patients on dialysis is elevated (>30%), and these antibodies correlate with mortality and cardiovascular morbidity. To evaluate the effect of IgA-aB2GPI-ab in patients with transplants, we followed all patients transplanted from 2000 to 2002 in the Hospital 12 de Octubre prospectively for 10 years. Presence of IgA-aB2GPI-ab in pretransplant serum was examined retrospectively. Of 269 patients, 89 patients were positive for IgA-aB2GPI-ab (33%; group 1), and the remaining patients were negative (67%; group 2). Graft loss at 6 months post-transplant was significantly higher in group 1 (10 of 89 versus 3 of 180 patients in group 2; P=0.002). The most frequent cause of graft loss was thrombosis of the vessels, which was observed only in group 1 (8 of 10 versus 0 of 3 patients in group 2; P=0.04). Multivariate analysis showed that the presence of IgA-aB2GPI-ab was an independent risk factor for early graft loss (P=0.04) and delayed graft function (P=0.04). There were no significant differences regarding patient survival between the two groups. Graft survival was similar in both groups after 6 months. In conclusion, patients with pretransplant IgA-aB2GPI-ab have a high risk of early graft loss caused by thrombosis and a high risk of delayed graft function. Therefore, pretransplant IgA-aB2GPI-ab may have a detrimental effect on early clinical outcomes after renal transplantation. 相似文献
12.
Improvement in Tricuspid Annular Plane Systolic Excursion with Pulmonary Hypertension Therapy in Pediatric Patients 下载免费PDF全文
13.
14.
Quality of life in stroke survivor–caregiver dyads: a new conceptual framework and longitudinal study protocol 下载免费PDF全文
15.
16.
17.
The Pedagogical Challenges of Teaching High School Bioethics: Insights from the Exploring Bioethics Curriculum 下载免费PDF全文
Mildred Z. Solomon David Vannier Jeanne Ting Chowning Jacqueline S. Miller Katherine F. Paget 《The Hastings Center report》2016,46(1):11-18
A belief that high school students have the cognitive ability to analyze and assess moral choices and should be encouraged to do so but have rarely been helped to do so was the motivation for developing Exploring Bioethics, a six‐module curriculum and teacher guide for grades nine through twelve on ethical issues in the life sciences. A multidisciplinary team of bioethicists, science educators, curriculum designers, scientists, and high school biology teachers worked together on the curriculum under a contract between the National Institutes of Health and Education Development Center, a nonprofit research and development organization with a long history of innovation in science education. At the NIH, the Department of Bioethics within the Clinical Center and the Office of Science Education within the Office of the Director guided the project.Our overarching goal for Exploring Bioethics was to introduce students to bioethics as a field of inquiry and to enable them to develop ethical reasoning skills so they could move beyond “gut reactions” to more nuanced positions. 相似文献
18.
19.
Michelle E. Wilson Charles Kim Jacqueline Carrasco 《Orbit (Amsterdam, Netherlands)》2016,35(5):288-291
A 48-year-old smoker with a history of hyperthyroidism treated 10 years prior to presentation with radioactive iodine ablation of the thyroid gland presented to his ophthalmologist with a 2-week history of transient loss of vision in the right eye occurring for 1 to 2 hours each morning. He denied ocular pain, diplopia or change in the prominence of one or both eyes. Examination revealed 2 mm of relative proptosis on the right, bilateral temporal flare and lower lid retraction. There was minimal upper lid retraction and no evidence of lid lag. Ocular motility was full. Dilated fundoscopic examination revealed bilateral optic nerve edema, right more than left. CT of the orbit demonstrated enlargement of the extraocular muscles bilaterally with marked enlargement of the right medial rectus and left inferior rectus muscles resulting in crowding at the orbital apex bilaterally. Laboratory testing revealed the patient to be hyperthyroid. The patient was treated with high dose oral steroids followed by orbital radiation. Hyperthyroidism was managed by the patient’s primary care physician. Visual symptoms rapidly improved with oral steroids and orbital radiation. Optic nerve edema completely resolved. Repeat CT imaging demonstrated a reduction in the enlargement of the extraocular muscles with relief of bilateral optic nerve compression. 相似文献