首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1363777篇
  免费   96454篇
  国内免费   1897篇
耳鼻咽喉   19043篇
儿科学   39240篇
妇产科学   35096篇
基础医学   203955篇
口腔科学   40736篇
临床医学   118532篇
内科学   259936篇
皮肤病学   29782篇
神经病学   102575篇
特种医学   52420篇
外国民族医学   142篇
外科学   217013篇
综合类   25606篇
现状与发展   1篇
一般理论   350篇
预防医学   95881篇
眼科学   31938篇
药学   106647篇
  3篇
中国医学   3030篇
肿瘤学   80202篇
  2018年   13254篇
  2016年   11243篇
  2015年   12723篇
  2014年   17212篇
  2013年   25915篇
  2012年   35203篇
  2011年   37461篇
  2010年   22067篇
  2009年   21016篇
  2008年   36439篇
  2007年   38439篇
  2006年   39318篇
  2005年   37808篇
  2004年   36569篇
  2003年   35181篇
  2002年   34533篇
  2001年   73612篇
  2000年   76194篇
  1999年   63242篇
  1998年   15264篇
  1997年   13383篇
  1996年   13762篇
  1995年   12809篇
  1994年   11885篇
  1993年   11045篇
  1992年   48146篇
  1991年   47056篇
  1990年   46052篇
  1989年   44730篇
  1988年   40948篇
  1987年   40121篇
  1986年   37510篇
  1985年   35983篇
  1984年   25871篇
  1983年   22063篇
  1982年   11677篇
  1981年   10395篇
  1979年   23833篇
  1978年   16467篇
  1977年   14041篇
  1976年   12788篇
  1975年   14265篇
  1974年   17225篇
  1973年   16187篇
  1972年   15555篇
  1971年   14825篇
  1970年   13953篇
  1969年   13186篇
  1968年   12139篇
  1967年   10998篇
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
21.
22.

Objectives

Expedient extubation after cardiac surgery has been associated with improved outcomes, leading to postoperative extubation frequently during overnight hours. However, recent evidence in a mixed medical-surgical intensive care unit population demonstrated worse outcomes with overnight extubation. This study investigated the impact of overnight extubation in a statewide, multicenter Society of Thoracic Surgeons database.

Methods

Records from 39,812 patients undergoing coronary artery bypass grafting or valve operations (2008-2016) and extubated within 24 hours were stratified according to extubation time between 06:00 and 18:00 (day) or between 18:00 and 6:00 (overnight). Outcomes including reintubation, mortality, and composite morbidity-mortality were evaluated using hierarchical regression models adjusted for Society of Thoracic Surgeons predictive risk scores. To further analyze extubation during the night, a subanalysis stratified patients into 3 groups: 06:00 to 18:00, 18:00 to 24:00, and 24:00 to 06:00.

Results

A total of 20,758 patients were extubated overnight (52.1%) and were slightly older (median age 66 vs 65 years, P < .001) with a longer duration of ventilation (4 vs 7 hours, P < .001). Day and overnight extubation were associated with equivalent operative mortality (1.7% vs 1.7%, P = .880), reintubation (3.7% vs 3.4%, P = .141), and composite morbidity-mortality (8.2% vs 8.0%, P = .314). After risk adjustment, overnight extubation was not associated with any difference in reintubation, mortality, or composite morbidity-mortality. On subanalysis, those extubated between 24:00 and 06:00 exhibited increased composite morbidity-mortality (odds ratio, 1.18; P = .001) but no difference in reintubation or mortality.

Conclusions

Extubation overnight was not associated with increased mortality or reintubation. These results suggest that in the appropriate clinical setting, it is safe to routinely extubate cardiac surgery patients overnight.  相似文献   
23.
Erosive pustular dermatosis of the scalp (EPDS) is an uncommon chronic inflammatory response to scalp trauma that usually resolves with cicatricial alopecia. It most commonly affects elderly patients with a history of actinic damage. Herein, we describe a 16‐year‐old girl with acrofacial dysostosis type 1 presenting after surgery with crusting purulent scalp lesions, whose clinical presentation and histopathologic findings were consistent with EPDS. A review of the literature on EPDS in children is also detailed.  相似文献   
24.
25.
26.
27.
28.
29.
30.
Acne vulgaris (acne) is a chronic inflammatory disease of the sebaceous gland, characterized by follicular hyperkeratinization, excessive colonization by Propionibacterium acnes (Pacnes) as well as immune reactions and inflammation. Despite an armamentarium of topical treatments available including benzoyl peroxide, retinoids and azelaic acid, topical antibiotics in monotherapies, especially erythromycin and clindamycin, are still used in Europe to treat acne. This intensive use led to antimicrobial‐resistant P. acnes and staphylococci strains becoming one of the main health issues worldwide. This is an update on the current topical acne treatments available in Europe, their mechanism of action, their potential to induce antimicrobial resistance and their clinical efficacy and safety.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号