Muallem endo-tracheal tube introducer: (METTI)--an aid for the difficult airway

This is a brief report evaluating a new single use endotracheal tube introducer (METTI) which has a soft curved atraumatic tip. The introducer was tried in 44 patients, whose direct laryngoscopic view was simulated to Cormack IIIb score, and in six patients with real Cormack III score. The overall success rate of railroading of the tracheal tube over the introducer was 94% from the first attempt.     

Application of a cuirass and institution of biphasic extra-thoracic ventilation by gear-protected physicians

OBJECTIVES: To evaluate the speed by which cuirass application, followed by biphasic extra-thoracic ventilation, can be instituted by full anti-chemical protective gear-wearing physicians. MATERIALS AND METHODS: Ten physicians of variable subspecialties applied a cuirass on an adult volunteer and instituted biphasic extra-thoracic ventilation, using the RTX respirator (Medivent, London, UK). Endotracheal (ET) intubation and manual ventilation of a mannequin and its ventilation was comparatively assessed. Performances were conducted in a prospective, crossover, randomized manner. Times to successful applications as well as failure rates were recorded. RESULTS: Cuirass application was performed more rapidly (102 +/- 9 s, 177 +/- 31 s, respectively, P <.01) and with a slightly lower failure rate than ET intubation. CONCLUSIONS: Physicians wearing full anti-chemical protective gear applied the cuirass and instituted biphasic extra-thoracic ventilation faster than ET intubation and manual positive pressure ventilation. Extra-thoracic ventilation should be further evaluated as an option for emergent respiratory support during toxic mass casualty events.     

Incidence of microbial infection after amniotic membrane transplantation

OBJECTIVE: To report the incidence and characteristics of microbial infection following amniotic membrane transplantation (AMT). METHODS: We retrieved the clinical and microbiological records of a total of 326 patients undergoing AMT from January 1994 to February 2001 at Bascom Palmer Eye Institute to determine the incidence and characteristics of post-AMT infections with respect to the interval between AMT and the time of microbial culturing, types of organisms, and clinical outcomes and to correlate these infections with the microbiologic results of AM storage media submitted immediately after AMT and the underlying ocular diagnosis. RESULTS: We subdivided these 326 patients into two groups: 76 patients (from January 1994 to June 1998) used AM prepared from a research laboratory and did not submit AM storage media for culture under an Institutional Review Board-approved protocol, and 250 patients thereafter used AM obtained from a commercial source and routinely submitted AM storage media for culture. A total of 11 culture-positive infections (3.4%) were identified, and among them 7 infections (9.2%) were from the first group, and 4 (1.6%) were from the second group (P = 0.004). All 4 infections (5.2%) occurring within 1 month after AMT were exclusively from the first group (P = 0.003). All AM storage media from the second group were culture negative. Gram-positive organisms were the most frequent isolate (64%). Infections were not correlated with the underlying ocular diagnosis. CONCLUSIONS: AMT is a safe method for ocular surface reconstruction with a very low rate of microbial infections, especially if AM is prepared according to Good Tissue Banking Practice set forth by FDA. Gram-positive isolates seem to be the most frequent isolates in infections after AMT.     

Hydrops fetalis secondary to parvovirus B19 infections

BACKGROUND: Fetal infection by human parvovirus B19 is a common cause of fetal anemia, nonimmune hydrops fetalis, and spontaneous abortion and can result in fetal death. Recent improvements in diagnosing parvovirus infections and the availability of intrauterine transfusion have reduced the overall rate of fetal loss after maternal exposure. METHODS: We report two cases of maternal parvovirus infection with classic findings of hydrops fetalis and review various aspects of parvovirus infection with emphasis on the developing management options in pregnancy. RESULTS AND CONCLUSIONS: Different management led to different results. In the first case there was normal neonatal and infantile development, and in the second case, the fetus died. With accurate laboratory testing, obstetric sonography, and fetal transfusion, the fetal mortality from parvovirus infection has been reduced considerably, and most pregnancies complicated by maternal parvovirus infection result in healthy outcomes.