Constructing Large Scale Cohort for Clinical Study on Heart Failure with Electronic Health Record in Regional Healthcare Platform: Challenges and Strategies in Data Reuse

Regional healthcare platforms collect clinical data from hospitals in specific areas for the purpose of healthcare management. It is a common requirement to reuse the data for clinical research. However, we have to face challenges like the inconsistence of terminology in electronic health records (EHR) and the complexities in data quality and data formats in regional healthcare platform. In this paper, we propose methodology and process on constructing large scale cohorts which forms the basis of causality and comparative effectiveness relationship in epidemiology. We firstly constructed a Chinese terminology knowledge graph to deal with the diversity of vocabularies on regional platform. Secondly, we built special disease case repositories (i.e., heart failure repository) that utilize the graph to search the related patients and to normalize the data. Based on the requirements of the clinical research which aimed to explore the effectiveness of taking statin on 180-days readmission in patients with heart failure, we built a large-scale retrospective cohort with 29647 cases of heart failure patients from the heart failure repository. After the propensity score matching, the study group (n=6346) and the control group (n=6346) with parallel clinical characteristics were acquired. Logistic regression analysis showed that taking statins had a negative correlation with 180-days readmission in heart failure patients. This paper presents the workflow and application example of big data mining based on regional EHR data.     

Transgendered and re‐flected borrowed Greek nouns in anatomical Latin

In this survey, almost 30 borrowed words in anatomical Latin were found to differ from the original Greek noun in gender and/or inflection. A third of these cases were judged to be errors. The rest are long‐standing or widely‐accepted exceptions to the usual adoption rules for borrowed Greek words. Possible linguistic explanations for these exceptions are presented. Clin. Anat. 31:306–309, 2018. © 2018 Wiley Periodicals, Inc.     

北美国际护理诊断定义与分类(2018-2020)修订解读

将北美国际护理诊断定义与分类(2018-2020)中护理诊断的名称、护理诊断的定义与护理诊断的指标与北美国际护理诊断定义与分类(2015-2017)进行了比较,从护理诊断的名称变更、定义与指标的修订,了解全球护理发展趋势.我国护士可参照北美国际护理诊断定义与分类(2018-2020),对临床病情判断精准性的提高、建立本土化的护理诊断分类系统及找到护理科研的选题素材,起到积极的意义.     

Complexity and health professions education: a basic glossary

Rationale and aims The study of health professions education in the context of complexity science and complex adaptive systems involves different concepts and terminology that are likely to be unfamiliar to many health professions educators. A list of selected key terms and definitions from the literature of complexity science is provided to assist readers to navigate familiar territory from a different perspective. Terms and concepts include agent, attractor, bifurcation, chaos, co‐evolution, collective variable, complex adaptive systems, complexity science, deterministic systems, dynamical system, edge of chaos, emergence, equilibrium, far from equilibrium, fuzzy boundaries, linear system, non‐linear system, random, self‐organization and self‐similarity.     

On English translation of infant Tuina points in traditional Chinese medicine

1 Introduction In recent years,several international standardized traditional Chinese medicine (TCM) nomenclatures have been published,including the major ones A Proposed Standard International Acupuncture Nomenclature by World Health Organization (WHO) in 1991[1],International Standard Terminologies on Traditional Medicine in the Western Pacific Region[2] by WHO in the Western Pacific Region (WPRO) in 2007 and International Standard Chinese-English Basic Nomenclature of Chinese Medicine[3] by the World Federation of Chinese Medicine Societies (WFCMS) in 2007.However,an English translation of points applied in infant Tuina therapy is neither contained in any of these standardized nomenclatures,nor in major Chinese-English dictionaries of Chinese medicine[4-6].Infant Tuina is an effective and common therapy used in the pediatric department of Chinese medicine.As the points used in infant Tuina therapy are different from the points used in standard acupuncture,and are essential to practice,the authors believe it is important to make an English translation of infant Tuina points and explore the principles and protocol of their translation.