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排序方式: 共有1761条查询结果,搜索用时 15 毫秒
1.
目的:探讨保妇康凝胶联合诺氟沙星治疗宫颈糜烂的临床效果。方法将100例宫颈糜烂患者根据随机数字表法分为观察组和对照组各50例。观察组给予保妇康凝胶和诺氟沙星联合治疗,对照组单独给予治糜灵栓治疗,比较两组患者临床症状的变化,并对临床疗效进行评价。结果观察组治愈率为86.00%,明显高于对照组的74.00%,临床症状评分改善较对照组明显,且其临床症状消失的时间短于对照组,差异均有统计学意义(P<0.05)。结论保妇康凝胶与诺氟沙星合用比治糜灵栓治疗宫颈糜烂效果更佳,且治愈时间上明显较优,值得临床上推广应用。 相似文献
2.
经皮椎间盘摘出联合医用臭氧治疗腰椎间盘突出症 总被引:6,自引:0,他引:6
目的探讨经皮髓核摘除术(PLD)联合医用臭氧注射治疗腰椎间盘突出症的临床效果及可行性。方法临床与影像检查确诊为腰椎间盘突出25例,先行PLD,后行椎间盘内及椎旁注射臭氧。结果25例病人治疗后经一年随访,治愈21例,有效24例,无效1例,无一例并发症。结论PLD联合医用臭氧治疗腰椎间盘突出症,安全可靠,可改善治疗效果,减少不良反应,值得推广应用。 相似文献
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目的观察卡前列甲酯栓(卡孕栓)对产后出血发生的影响及其副作用。方法将正常足月妊娠阴道分娩者80例随机分成3组,其中2组为卡孕栓实验组,以不同给药途径分为阴道用药组(25例)与舌下含服组(25例),对照组(30例)则常规静脉推注麦角新碱。结果3组产妇的第3产程平均时间分别是7.64、5.52和6.44min,无明显统计学差异(P>0.05);产后2h内的平均出血量,对照组(260.83ml)与卡孕栓阴道给药组(190.28ml)及舌下含服组(199.80ml)相比均有显著差异(P<0.001);两卡孕栓组间则未见差异。两实验组产妇均未发生明显副反应。结论卡孕栓预防产后出血的效果优于麦角新碱,其阴道用药及舌下含服都是有效给药途径。 相似文献
5.
Yukio Fukuyama Tohru Seki Chikaya Ohtsuka Hisao Miura Michiko Hara 《Brain & development》1996,18(6):144-484
Recent studies have shown that adequate medication can prevent the recurrence of febrile seizures (FS). It has also been clarified that the vast majority of, though not all, FS patients follow a benign course. Then, questions arise as to whether or not FS should be prevented, particularly in light of the risks of side effects from drugs. Which kinds of FS can be prevented, if necessary? The guidelines presented here are aimed primarily at helping general practitioners in considering how to manage FS most appropriately. The guidelines stress that judgements should be individualized, while referring to a few specific ‘warning factors’. The guidelines follow a ‘laissez-faire’ principle for the majority of FS cases, whereas intermittent therapy with diazepam and continuous medication with either phenobarbital or valproate are indicated in other limited cases meeting respective definite criteria. 相似文献
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BACKGROUND: Reduction of house dust mite allergens in the domestic environment can play an important part in reducing sensitization and in the amelioration of symptoms in atopic individuals. Chemical and physical methods have been tried with varied levels of success. The present paper presents a novel electrostatic way of destroying Der p 1, the major mite allergen. OBJECTIVE: To assess the efficacy of negative Trichel, negative continuous glow, positive pulse and positive continuous glow corona in destroying Der p 1. To determine whether ozone has any effect on the integrity of Der p 1 in the experimental conditions present. METHODS: A simple point-to-plane apparatus was used to irradiate samples of Der p 1 for periods of 1, 15, 30, 45, 60, 120, 180, 240 and 300 min. Controls were exposed to the atmosphere with no corona products present for the equivalent time. The effect of the corona by-product ozone was investigated alone by exposing samples of Der p 1 to molecular ozone for 60 min. Der p 1 concentration was quantified by two-site monoclonal antibody ELISA. RESULTS: High current negative glow resulted in a 67.37% reduction in Der p 1 concentration after 300 min compared with a 50.5% reduction from a low current Trichel regime. High current positive glow corona gave a reduction of 25.22% while a low current positive pulse corona caused a 13.72% reduction after 300 min. All these reductions were statistically significant (P < 0.05) compared with unexposed controls. Negative corona always gave greater percentage reductions in Der p 1 concentration for each time exposure investigated. The pattern of percentage reduction follows an exponential rise to maximum relationship in respect to time. Samples of Der p 1 were not affected by exposure to molecular ozone. CONCLUSION: These data indicate corona products to be a powerful new method of destroying Der p 1 allergen that is not dependent on the presence of the oxidizing corona product ozone. 相似文献
8.
目的 研究雌激素联合保妇康栓治疗绝经后宫颈人乳头瘤病毒(HPV)感染的临床疗效。方法 选取2019年2月—2022年7月无锡市第九人民医院收治的89例绝经后宫颈HPV感染患者,按治疗方法不同分为研究组(46例)和对照组(43例)。对照组接受雌激素治疗,研究组在对照组基础上接受保妇康栓治疗。两组均持续治疗3个月。对比两组异常分泌物持续时间、HPV转阴时间、临床疗效、炎症因子、免疫功能、液基薄层细胞学检查(LCT)评分与宫颈炎症评分及不良反应。结果 研究组异常分泌物持续时间、HPV转阴时间均短于对照组(P <0.05)。研究组总有效率高于对照组(P <0.05)。研究组治疗前后白细胞介素-4、γ干扰素、白细胞介素-2、肿瘤坏死因子-α的差值均高于对照组(P <0.05)。研究组治疗前后CD3+、CD19+、CD3+CD8+、CD3-CD56+的差值均高于对照组(P <0.05)。研究组治疗前后LCT评分、宫颈炎症评分的差值均高于对照组(P <0.05)... 相似文献
9.
Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells 总被引:2,自引:0,他引:2
P. O. Depuydt B. N. Lambrecht G. F. Joos R. A. Pauwels 《Clinical and experimental allergy》2002,32(3):391-396
BACKGROUND: Epidemiological studies suggest that ozone exposure is related to increased asthma symptoms. Dendritic cells (DCs) are the principal antigen-presenting cells in the airways. OBJECTIVE: We have examined whether ambient doses of ozone (100 ppb for 2 h) enhance allergic sensitization and/or airway inflammation in a mouse model. METHODS: C57BL/6 mice were sensitized to inhaled ovalbumin (OVA) by intratracheal instillation of OVA-pulsed DCs on day 0. Daily exposure to OVA aerosol on days 14-20 resulted in an eosinophilic airway inflammation, as reflected in bronchoalveolar lavage fluid and lung histology. In a first experiment, mice were exposed to ozone or room air immediately prior to and following sensitization. Subsequently, we tested the effect of ozone exposure during antigen challenge in DC-sensitized mice. RESULTS: Exposure to ozone during sensitization did not influence airway inflammation after subsequent allergen challenge. In contrast, in sensitized mice, challenge with OVA together with ozone (days 14-20) resulted in enhanced airway eosinophilia and lymphocytosis, as compared with mice exposed to OVA and room air (1.91 x 106 +/- 0.46 x 106 vs. 0.16 x 106 +/- 0.06 x 106 eosinophils/mL lavage fluid; P = 0.015; 0.49 x 106 +/- 0.11 x 106 vs. 0.08 x 106 +/- 0.03 x 106 lymphocytes/mL lavage fluid; P = 0.004). Ozone exposure without subsequent OVA exposure did not cause airway inflammation. CONCLUSION: Ozone exposure does not increase allergic sensitization but enhances antigen-induced airway inflammation in mice that are sensitized via the airways. 相似文献
10.
该研究首先阐述了婴儿培养箱消毒的重要性,然后从臭氧的消毒机理展开讨论,根据婴儿培养箱的结构特点和臭氧消毒的优势,结合临床应用得到臭氧消毒的实现原理,提出一种外置注入式婴儿培养箱消毒装置的设计方法。该设计通过在婴儿培养箱箱体外安装一套消毒装置,利用该装置中的电子臭氧发生器现场制取臭氧消毒气体,经输气管将臭氧消毒气体注入婴儿培养箱箱体内,在一定浓度和时间的作用下达到消毒的目的,为婴儿培养箱消毒提供了一套安全有效、简单实用的臭氧消毒方法,且该消毒装置具有设计合理、创意新颖、制作简单、操作方便,以及消毒无死角、无二次残留污染等优点。 相似文献