全文获取类型
收费全文 | 31302篇 |
免费 | 3604篇 |
国内免费 | 578篇 |
专业分类
耳鼻咽喉 | 244篇 |
儿科学 | 1136篇 |
妇产科学 | 539篇 |
基础医学 | 3230篇 |
口腔科学 | 797篇 |
临床医学 | 5769篇 |
内科学 | 4604篇 |
皮肤病学 | 436篇 |
神经病学 | 1542篇 |
特种医学 | 773篇 |
外国民族医学 | 5篇 |
外科学 | 3729篇 |
综合类 | 4490篇 |
预防医学 | 2228篇 |
眼科学 | 223篇 |
药学 | 2996篇 |
15篇 | |
中国医学 | 1707篇 |
肿瘤学 | 1021篇 |
出版年
2024年 | 130篇 |
2023年 | 694篇 |
2022年 | 991篇 |
2021年 | 1471篇 |
2020年 | 1264篇 |
2019年 | 1641篇 |
2018年 | 2063篇 |
2017年 | 1124篇 |
2016年 | 1086篇 |
2015年 | 1021篇 |
2014年 | 2336篇 |
2013年 | 2456篇 |
2012年 | 1834篇 |
2011年 | 1865篇 |
2010年 | 1480篇 |
2009年 | 1402篇 |
2008年 | 1298篇 |
2007年 | 1302篇 |
2006年 | 1200篇 |
2005年 | 1268篇 |
2004年 | 875篇 |
2003年 | 643篇 |
2002年 | 554篇 |
2001年 | 435篇 |
2000年 | 581篇 |
1999年 | 531篇 |
1998年 | 521篇 |
1997年 | 354篇 |
1996年 | 324篇 |
1995年 | 236篇 |
1994年 | 281篇 |
1993年 | 269篇 |
1992年 | 354篇 |
1991年 | 156篇 |
1990年 | 268篇 |
1989年 | 147篇 |
1988年 | 190篇 |
1987年 | 141篇 |
1986年 | 110篇 |
1985年 | 111篇 |
1984年 | 104篇 |
1983年 | 53篇 |
1982年 | 75篇 |
1981年 | 40篇 |
1980年 | 35篇 |
1979年 | 29篇 |
1978年 | 19篇 |
1977年 | 19篇 |
1976年 | 21篇 |
1971年 | 19篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Zongzhang Huang Qigu Yao Jianping Zhu Ying He Yanghao Chen Feng Wu Teng Hua 《Diagnostic and interventional imaging》2021,102(5):279-285
PurposeThe purpose of this study was to make a systematic review and meta-analysis to determine the stent diameter (8 mm vs. 10 mm) that conveys better safety and clinical efficacy for transjugular intrahepatic portosystemic shunt (TIPS).Materials and methodsFour databases were used to identify clinical trials published from inception until March 2020. Data were extracted to estimate and compare one-year and three-year overall survivals, hepatic encephalopathy, variceal rebleeding, and shunt dysfunction rates between patients with 8 mm covered stents and those with 10 mm covered stents.ResultsFive eligible studies were selected, which included 489 patients (316 men, 173 women). The 8 mm covered stent group had higher efficacy regarding one-year or three-year overall survival (odds ratio [OR], 2.88; P = 0.003) and (OR, 1.81; P = 0.04) and lower hepatic encephalopathy (OR, 0.69; P = 0.04) compared with 10 mm covered stent group. There were no significant differences in variceal rebleeding rate (OR 0.80; P = 0.67). However, shunt dysfunction was lower in 10 mm covered stent group (OR, 2.26; P = 0.003).ConclusionsOur results suggest that the use of 8 mm covered stents should be preferred to that of 10 mm covered stents for TIPS placement when portal pressure is frequently monitored. 相似文献
3.
4.
5.
《Journal of vascular and interventional radiology : JVIR》2022,33(4):359-367.e8
PurposeTo review and to compare indirectly the outcomes of minimally invasive therapies for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.Materials and MethodsA literature search via Medline and Cochrane Central databases was completed for randomized control studies published between January 2000 to April 2020 for the following therapies: Rezum, Urolift, Aquablation, and prostatic artery embolization (PAE). Data on the following variables were included: International prostate symptom score (IPSS), maximum urinary flow rate, quality of life, and postvoid residual (PVR). Standard mean differences between treatments were compared through a meta-analysis using transurethral resection of the prostate (TURP) to assess differences in treatment effect.ResultsThere was no significant difference in outcomes between therapies for IPSS at the 3, 6, and 12-month follow ups. Although outcomes for Rezum were only available out to 3 months, there were no consistently significant differences in outcomes when comparing Aquablation versus PAE versus Rezum. TURP PVR was significantly better than Urolift at 3, 6, and 12 months. No significant differences in minor or major adverse events were noted.ConclusionAlthough significant differences in outcomes were limited, Aquablation and PAE were the most durable at 12 months. PAE has been well studied on multiple randomized control trials with minimal adverse events while Aquablation has limited high quality data and has been associated with bleeding-related complications. 相似文献
6.
目的 系统评价中药治疗哮喘-慢阻肺(ACO)的疗效与安全性。方法 全面检索PubMed、Cochrane Library、Web of Science、中国知网、万方、维普、中国医学文献数据库,纳入有关中医药治疗ACO的随机对照试验(RCT),运用Cochrane手册对纳入研究的方法学质量进行评估,采用Review Manager 5.3进行Meta分析。结果 共纳入32项RCT,包括2688例ACO患者,其中试验组1361例,对照组1327例。Meta分析结果显示,中医药可以显著改善ACO患者的中医证候疗效[RR=1.19,95% CI(1.13,1.25),P<0.00001]、CAT评分[MD=-3.62,95% CI(-4.37,-2.87),P<0.00001]、ACT评分[MD=3.42,95% CI(2.23,4.62),P<0.00001],、中医证候总积分[MD=-3.61,95% CI(-4.83,-2.39),P<0.00001]、FEV1[MD=0.59,95% CI(0.08,1.10),P=0.02]、FEV1%[MD=8.61,95% CI(5.20,12.1),P<0.00001]、FEV1/FVC[MD=6.52,95% CI(4.24,8.80),P<0.00001]、6 min步行实验[MD=41.18,95% CI(22.15,60.21),P<0.0001]、急性发作次数[MD=-2.46,95% CI(-3.62,-1.13),P<0.0001]。所有研究均未报道严重不良反应。结论 中药治疗ACO,可以显著提高临床疗效,改善患者的肺功能且具有较好安全性,但是需要更高质量、多样本、多中心的随机对照试验进一步确认。 相似文献
7.
《Anaesthesia and Intensive Care Medicine》2019,20(11):644-650
This article focuses on the functional features of positive-pressure ventilators, the modes of invasive and non-invasive mechanical ventilation, and the main ventilator settings. It also highlights the potential complications of mechanical ventilation, the basic principles of weaning, and the pathophysiological basis of patient-ventilator dyssynchrony. 相似文献
8.
赵建刚 《中国中西医结合外科杂志》2020,26(3):452-456
目的:探讨右美托咪啶与芬太尼联合在ICU腹部外科术后机械通气患者中的应用效果及对镇静、镇痛作用的影响。方法:选择2018年5月—2019年6月ICU腹部外科术后机械通气患者62例,随机分为对照组(n=31例)和观察组(n=31例)。两组均采用芬太尼持续静脉泵入,对照组采用咪达唑仑镇静镇痛,观察组采用右美托咪啶镇静镇痛,比较两组镇痛镇静效果、镇静剂使用剂量、苏醒及达到镇静所需时间、血流动力学水平及安全性。结果:两组T2、T3时间点VAS评分分别为(2.40±0.31 vs 2.43±0.32和2.01±0.12 vs 2.05±0.15)、Ramsay量表评分分别(3.21±0.35 vs 3.20±0.33和3.01±0.25vs 3.00±0.24)均低于T1时间点(VAS评分2.94±0.69 vs 2.96±0.71;Ramsay量表评分3.57±0.61 vs 3.58±0.62)(P0.05);观察组右美托咪啶联合芬太尼镇痛镇静达到镇静所需时间(34.29±3.56) min长于对照组(23.63±3.21)(t=5.535,P=0.043);观察组镇静剂使用剂量(220.59±15.25)μg、苏醒时间(3.29±0.69)min均少(短)于对照组镇静剂使用剂量(386.44±18.92)μg、苏醒时间(7.56±1.21)min(t=6.294、6.092,P=0.023、0.025);两组T1、T2时间点心率[观察组T1(88.47±9.76)次/min、T2(86.41±9.43)次/min;对照组T1(89.53±10.41)次/min、T2(87.46±9.58)次/min]均高于T0时间点[观察组(78.78±4.35)次/min、对照组(79.12±4.41)次/min](P0.05);观察组T1、T2时间点MVP(79.58±5.71、87.53±6.76)mmHg高于对照组(74.12±4.69、75.26±5.61)mmHg(t=9.613、7.223,P=0.011、0.016);观察组的不良反应发生率为6.45%,与对照组的12.90%差异无统计学意义(χ~2=1.214, P=0.643)。结论:将右美托咪啶联合芬太尼用于ICU腹部外科术后机械通气患者中能获得良好的镇痛、镇静效果,缩短苏醒及达到镇静所需时间,血流动力学相对稳定,药物安全性较高,值得推广应用。 相似文献
9.
Elizabeth D. Krebs Robert B. Hawkins J. Hunter Mehaffey Clifford E. Fonner Alan M. Speir Mohammed A. Quader Jeffrey B. Rich Leora T. Yarboro Nicholas R. Teman Gorav Ailawadi 《The Journal of thoracic and cardiovascular surgery》2019,157(4):1533-1542.e2