Plastic surgery for the management of palmoplantar keratodermia (Palmoplantoneoplasty)

Keratodermia is an incurable genetic and regional disease located in the palmar and plantar regions. The author reports his experience with five cases of palmoplantar keratodermia that were treated by grafting onto the soles and the palms skin taken from the calves and the thighs.     

Neglected rupture of the Achilles tendon treated with peroneus brevis transfer: A functional assessment of 5 cases

The purpose of this study was to review the clinical results of 5 patients who underwent repair of a chronic Achilles tendon rupture using a combination of peroneus brevis transfer and plantaris tendon augmentation. The technique belongs to the group of local tendon transfer procedures making use of the transferred peroneus brevis tendon as strengthening material together with the plantaris tendon as suturing material. There were 4 males and 1 female with an average age of 49.4 years and an average time to presentation postinjury of 19.8 weeks (range 5-40 wk). All patients underwent Cybex strength testing before and approximately 1 year after surgery. This testing demonstrated a postoperative improvement in peak plantarflexion torque (Newton-meters/body weight) in all cases. The peak torque of plantar flexion increased in all patients (range, 21%-410%). Four patients were found to have an increase of the dorsal flexors peak torque (range, 31%-290%), whereas one patient showed a decrease (-37%). No patient experienced wound closure complications, postoperative pain, or functional limitations. In spite the possibility of residual lateral ankle instability, we found this modification to be a valuable innovation that offers a very good functional result, low morbidity, technical advantages to the surgeon and, most important, a durable and satisfactory result for the patients.     

跖肌腱移植的应用解剖

目的:为临床进行跖肌腱移植提供解剖学依据。方法:对68例(共120侧,其中男84侧,女36侧)防腐固定标本下肢进行跖肌腱移植的应用解剖及形态学测量。结果:跖肌腱长(30.59±2.49)cm,与下肢长度之比为0.38±0.02。根据外形特点跖肌腱可划分为上、中、下3段,宽度分别为(3.58±0.76)mm,(2.44±0.52)mm,(1.67±0.30)mm;厚度分别为(0.45±0.11)mm,(0.56±0.13)mm,(0.74±0.17)mm。跖肌腱终止方式分为A,B,C,D4型,构成比分别为55.00%,28.33%,13.33%和3.33%;跖肌腱止端横截面积为(11.52±7.45)mm2。结论:提供的跖肌腱解剖学数据,为临床跖肌腱取材提供了形态学依据。     

PAX3/7 expression coincides with MyoD during chronic skeletal muscle overload

Paired box (Pax) proteins 3 and 7 are key determinants for embryonic skeletal muscle development by initiating myogenic regulatory factor (MRF) gene expression. We show that Pax3 and 7 participate in adult skeletal muscle plasticity during the initial responses to chronic overload (< or =7 days) and appear to coordinate MyoD expression, a member of the MRF family of genes. Pax3 and 7 mRNA were higher than control within 12 h after initiation of overload, preceded the increase in MyoD mRNA on day 1, and peaked on day 2. On days 3 and 7, Pax7 mRNA remained higher than control, suggesting that satellite cell self-renewal was occurring. Pax3 and 7 and MyoD protein levels were higher than control on days 2 and 3. These data indicate that Pax3 and 7 coordinate the recapitulation of developmental-like regulatory mechanisms in response to growth-inducing stimuli in adult skeletal muscle, presumably through activation of satellite cells.     

Porokeratosis plantaris,palmaris et disseminata mit multiplen filiformen Hyperkeratosen und Nageldystrophie

Zusammenfassung Wir berichten über eine Familie mit Porokeratosis plantaris, palmaris et disseminata (PPPD). Als besondere klinische Variante konnten wir beim Vater eine Assoziation mit multiplen filiformen Hyperkeratosen dokumentieren. Ebenfalls erstmalig bei dieser Entit?t beobachteten wir einen Nagelbefall mit sekund?rer Nageldystrophie. Bei der Tochter sind die Porokeratoseherde anf?nglich am Stamm aufgetreten und haben sich erst sp?ter palmoplantar ausgebildet. Diese Chronologie der Krankheitsentwicklung ist seltener in der Literatur erw?hnt worden. Normalerweise manifestiert sich die PPPD zuerst palmoplantar und breitet sich sp?ter auf das restliche Integument aus. Eingegangen am 18. August 1994 Angenommen am 25. Oktober 1994     

平阳霉素局部注射治疗多发性跖疣

目的观察平阳霉素局部注射治疗多发性跖疣的疗效。方法126例多发性跖疣患者随机分为治疗组及对照组,治疗组采用平阳霉素局部注射进行治疗,对照组采用液氮冷冻治疗法。结果治疗组有效率为90．48％,对照组有效率为74．60％,2组比较,差异有统计学意义（χ2=5．51,P〈0．05）。结论平阳霉索局部注射治疗多发性跖疣,效果好,复发率低,不良反应少。     

中草药治疗掌跖脓疱病临床疗效的理论研究

目的 研究中草药治疗掌跖脓疱病疗效的理论规律。方法 采用中药方剂治疗相应证型的掌跖脓疱病病人,并阐述疗效的内在规律。结果 治疗后疗效十分显著,疗效与中药方剂的药理作用有明确的对应性。结论 西医理论与中医理论的有机结合是认识与治疗掌跖脓疱病的重要指南。     

艾拉光动力治疗尖锐湿疣及多发性跖疣临床疗效观察

目的:观察艾拉光动力疗法(5-盐酸氨酮戊酸光动力疗法,5-aminolevulinie acid photodynamic therapy,ALA-PDT)治疗尖锐湿疣(Condyloma acuminatum,CA)及多发性跖疣(Verruca phmtaris,PS)的安全性与疗效.方法:以ALA-PDT治疗151例CA及PS患者,末次治疗后第1周进行疗效评价,第4、8周和12周观察复发率和不良反应.结果:疗程结束后CA及PS的疣体清除率分别为96.5%和75.4%,治疗后复发率分别为12.1%和16.3%.未发生系统不良反应,局部不良反应发生率分别为10.47%和3.08%,主要为烧灼感,局部红肿.结论:ALA-PDT治疗CA及PS治愈率均较高,但治疗CA疗效更好.复发率低,安全性好.