首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   5971篇
  免费   362篇
  国内免费   102篇
耳鼻咽喉   59篇
儿科学   164篇
妇产科学   92篇
基础医学   509篇
口腔科学   58篇
临床医学   609篇
内科学   904篇
皮肤病学   64篇
神经病学   342篇
特种医学   1389篇
外国民族医学   3篇
外科学   334篇
综合类   526篇
预防医学   255篇
眼科学   67篇
药学   530篇
  4篇
中国医学   85篇
肿瘤学   441篇
  2024年   7篇
  2023年   107篇
  2022年   174篇
  2021年   253篇
  2020年   220篇
  2019年   230篇
  2018年   212篇
  2017年   175篇
  2016年   189篇
  2015年   167篇
  2014年   404篇
  2013年   421篇
  2012年   306篇
  2011年   313篇
  2010年   231篇
  2009年   300篇
  2008年   327篇
  2007年   270篇
  2006年   254篇
  2005年   219篇
  2004年   175篇
  2003年   173篇
  2002年   125篇
  2001年   126篇
  2000年   79篇
  1999年   105篇
  1998年   67篇
  1997年   96篇
  1996年   59篇
  1995年   88篇
  1994年   94篇
  1993年   64篇
  1992年   45篇
  1991年   47篇
  1990年   19篇
  1989年   16篇
  1988年   30篇
  1987年   16篇
  1986年   22篇
  1985年   32篇
  1984年   35篇
  1983年   20篇
  1982年   28篇
  1981年   23篇
  1980年   15篇
  1979年   11篇
  1978年   6篇
  1977年   13篇
  1976年   10篇
  1973年   5篇
排序方式: 共有6435条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.

Background

The purpose of this analysis is to describe the differences in cardiac magnetic resonance characteristics between benign and malignant tumors, which would be helpful for surgical planning.

Methods

This was a prospective cohort study of 130 patients who underwent cardiac magnetic resonance imaging for evaluation of a suspected cardiac mass. After excluding thrombi and tumors without definitive diagnosis, 66 tumors were evaluated for morphologic features and tissue composition.

Results

Of the 66 patients, 39 (59.0%) had malignant tumors and 27 (41.0%) had benign tumors. Patients with malignant tumors were younger when compared with those with benign tumors (age 51 years [42.8-60.0] vs 65 years [60.0-71.0] median). Malignant tumors more often demonstrated tumor invasion (69% vs 0% P < .001) and were more often associated with pericardial effusion (41% vs 7.4% P = .004). Presence of first-pass perfusion (100% vs 33% P < .001) and late gadolinium enhancement (100% vs 59.2%, P < .001) were significantly higher in malignant tumors. In logistic regression modeling, tumor invasion (P < .001) and first-pass perfusion (P < .001) were independently associated with malignancy. Furthermore, using classification and regression tree analysis, we developed a decision tree algorithm to help differentiate benign from malignant tumors (diagnostic accuracy ~90%). The algorithm-weighted cost of misclassifying a malignant tumor as benign was twice that of classifying a benign tumor as malignant.

Conclusions

Our study demonstrates that cardiac magnetic resonance imaging is a useful noninvasive method for differentiating malignant from benign cardiac tumors. Tumor size, invasion, and first-pass perfusion were useful imaging characteristics in differentiating benign from malignant tumors.  相似文献   
5.
Objective: To investigate the ability of contrast enhancement patterns of contrast-enhanced ultrasound in differentiating benign and malignant soft tissue tumours.  相似文献   
6.
Purpose:It has been reported previously that intravenously administered gadolinium-based contrast agent (GBCA) leaks into the subarachnoid space around the cortical veins at 4 h after injection in all old people over 37 years, but not in younger people up to 37 years of age in 3D-real IR images. The purpose of this study was to investigate whether there was a strict threshold of 37 years of age for the leakage of the GBCA into the subarachnoid space.Methods:The subjects included 190 patients, that were scanned for 3D-real IR images at 4 hours after intravenous injection of GBCA as a diagnostic test for endolymphatic hydrops. The patient’s age ranged from 14 to 81 years. Two experienced neuroradiologists evaluated the images to determine whether the GBCA leakage around the cortical veins was positive or negative. Any discrepancies between the two observers were discussed and a consensus was obtained.A Mann–Whitney U test and receiver operating characteristic (ROC) curve analysis were used to compare the positive and the negative group and to set the age cut-off value for the prediction of GBCA leakage.Results:The GBCA leakage around the cortical veins was negative in 35 patients and positive in 155 patients. The average age was 33 ± 11 years in the negative group, and 55 ± 12 years in the positive group (P < 0.01). In the ROC analysis for the age and leakage of the GBCA, an area under the curve was 0.905 and the cut-off age was 37.317 years (sensitivity of 0.942 and specificity of 0.771).Conclusion:Intravenously administered GBCA leaks into the subarachnoid space around the cortical veins in most patients over 37 years of age. However, it should be noted that it can be found occasionally in patients under 37 years of age.  相似文献   
7.
高压氧治疗急性一氧化碳中毒174例护理效果观察   总被引:5,自引:0,他引:5  
急性CO中毒是我国北方地区冬季的常见病,多发病。若治疗不及时或不彻底又有发生CO中毒迟发性脑病的危险。自从高压氧医学产生和发展以来,目前已成为CO中毒首选的主要治疗手段,取得了很好的治疗效果。本文对近3年来用高压氧(HBO)配合临床药物治疗CO中毒及迟发性脑病174例的治疗护理效果进行了观察,认为对急性CO中毒患者的治疗护理应及早发现、及早就医、及早HBO治疗并坚持足够的疗程,可以提高CO中毒的治愈率,降低死亡率,减少或减轻迟发性脑病的发生,同时认为整个HBO治疗过程中做好每个环节的护理工作是CO中毒患者救治成功的关键。1…  相似文献   
8.
目的 探讨各种脑膜病变脑膜MRI强化类型与病因的关系。方法 回顾性分析78例资料完整,MRI增强扫描脑膜异常强化的非脑膜瘤。结果 78例中,脑膜癌病16例(硬脑膜-蛛网膜型2例,软脑膜-蛛网膜下腔型11例,混合型3例);感染性脑膜炎18例(硬脑膜-蛛网膜型3例,软脑膜-蛛网膜下腔型13例,混合型2例);脑梗死22例(软脑膜-蛛网膜下腔型18例,混合型4例);开颅术后15例(硬脑膜-蛛网膜型10例,混合型5例);硬膜下积液(血肿)7例,均为硬脑膜-蛛网膜型。结论 MRI双倍剂量Gd-DTPA增强扫描对脑膜病变敏感性高,脑膜强化类型与各种病因侵犯脑膜三层结构的方式和程度有关。  相似文献   
9.
Enhanced and non-enhanced computed tomography (CT) brain scans were performed within 72 h of surgery on 21 children in whom brain tumors had been resected totally or subtotally, and scans were repeated at varying intervals thereafter. Biopsies of the resection margins were performed in 12 patients at the end of the surgical procedure. The immediate CT scan showed enhancement in the resection margin in 13 of the 21 patients and in 9 of the 13, the enhancement disappeared on follow-up scans. There was discordance between the results of immediate CT scan examination and the biopsies of the resection margins in 7 of the 12 cases. The advantages and disadvantages of an immediate postoperative scan versus a more delayed CT scan are discussed.  相似文献   
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号