单片微机化微弱发光测量仪及其在肿瘤研究中的初步应用

单片微机化微弱发光测量仪由中科院生物物理所和北京科龙生物医学技术开发公司研制成功。该仪器适用于肿瘤研究中生物医学样品的微弱发光的测量。测量样品的重复性优于０．８％，稳定性优于０．５％，线性相关系数达０．９９９７，不仅可以进行样品的发光强度测量，还可以进行动力学曲线的测量以及样品发射光谱的测量。光谱在４００ｎｍ－７５０ｎｍ范围内。测量方式可选择手动、半自动和自动计时三种。测量结果表明，荷瘤裸鼠血液微     

中子和γ线微观能量沉积谱的测量

我们用自制的组织等效圆柱形正比计数管和低噪声前置放大器测量了⁶⁰Co、¹³⁷Cs,²²⁶Ra,²⁴¹Am～Be中子积14MeV中子的微观能量沉积谱.为保证计数管内所充的组织当置气体成分恒定,使用了流气系统.实验结果表明.3种γ线的能量沉积谱很相似,其y值分布在0.06～15keV/μ范围内,而中予的y值分布在0.03～930keV/μ范围内.剂量平均线能yD是一个重要的微剂量参数,借助于它可预示生物效应.我们计算了不同射线的yD值,发现中子的yD值要比γ线大几十倍.     

INVESTIGATION OF TUMORIGENIC EFFECT ON ULTRAWEAK LUMINESCENCE FROM NUDE MOUSE FOR ANIMAL MODEL

With nude mouse for animal model, this paper has investigated its whole body luminescence after or before it was inoculated with tumor, and the relationship between tumorigenesis and the luminescence, then, studied the luminescence difference from different mouse organs and find out sensitive luminescence organs. Furthermore, it has tested possibie luminescence mechanism with beta- carotene, NaN3 and D2O. This paper is supposed to provide a new feasible method for cancer diagnosis.