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1.
高血压脑出血125例手术治疗分析   总被引:8,自引:1,他引:7  
目的 探讨手术治疗对高血压脑出血的临床效果.方法 对我科2000-05~2008-11收治的125例高血压脑出血患者的临床资料进行回顾性分析.结果 骨窗开颅手术45例,存活32例(71.1%),恢复良好13例(40.6%),中、重残19例(59.4%),死亡13例(28%);微创血肿清除80例,存活70例(87.5%),恢复良好36例(51.4%),中、重残34例(48.6%),死亡10例(12.5%).微创血肿清除术后,病人的存活率和恢复情况均高于开颅手术组,病死率明显低于开颅手术组.结论 手术治疗能明显提高存活率,微创血肿清除术要比开颅手术优,既能提高存活率,又能大大提高生存质量,是一种治疗高血压脑出血安全、及时、有效的手术方式.  相似文献   

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目的探讨微创颅内血肿清除术与小骨窗开颅血肿清除术治疗重症高血压脑出血的疗效。方法回顾性分析2010-02—2014-03我院收治的重症高血压脑出血患者102例,采用微创颅内血肿清除术治疗的52例患者为观察组,采用小骨窗颅内血肿清除术治疗50例患者为对照组,观察2组患者手术前后血肿量、神经功能缺损情况与并发症发生率。结果观察组术后第1、3天血肿量高于对照组(P<0.05);第7天血肿量与对照组比较差异无统计学意义(P>0.05),2组神经功能缺损情况均有所改善,观察组改善程度优于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05)。结论微创颅内血肿清除术对重症高血压脑出血患者神经功能缺损改善程度与并发症控制程度优于小骨窗开颅血肿清除术,值得临床推广应用。  相似文献   

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目的:观察微创血肿冲洗引流术治疗中等量高血压脑出血的临床疗效,并分析对其神经功能恢复的影响。方法中等量高血压脑出血患者85例,根据治疗方法分为观察组(微创血肿冲洗引流术治疗)与对照组(小骨窗开颅血肿清除术治疗),使用改良Rankin量表(MRS)与Barthel指数(BI)评估临床疗效,观察神经功能恢复状况。结果观察组治疗后神经功能评分(SSS)与BI评分显著提高,明显高于对照组,MRS明显降低且低于对照组,差异有统计学意义(P<0.05)。结论微创血肿冲洗引流术治疗中等量高血压脑出血,有助于改善临床症状,恢复神经功能状况,并有效提高患者生活能力,值得临床应用。  相似文献   

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微创术和小骨窗开颅术治疗高血压脑出血临床疗效分析   总被引:2,自引:1,他引:1  
目的探讨微创治疗高血压性脑出血的疗效。方法高血压脑出血患者70例,随机分为小骨窗组及微创组。小骨窗组予以小骨窗开颅术治疗,微创组予以微创颅内血肿清除术治疗,观察并比较2组间的疗效。结果微创组在血肿清除率、病死率以及神经功能恢复方面均明显优于对照组(P<0.05)。结论微创颅内血肿清除术治疗高血压脑出血是一种较好的方法,能明显减少患者的病死率,并能有效改善患者的神经功能缺损程度。  相似文献   

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微创小骨窗开颅血肿清除治疗高血压脑内血肿   总被引:12,自引:0,他引:12  
目的 评价小骨窗开颅治疗高血压脑出血的疗效。方法 采用小骨窗开颅清除血肿,同时在血肿腔内置人引流管,术后应用尿激酶溶解残留血肿。结果 术后3d复查头CT,16例血肿清除70%左右,4例血肿清除70%-80%,1例血肿清除95%。随3血个月,GOS良18例,中3例。结论 小骨窗开颅手术具有微创,减压满意,术后病人并发症少等优点。  相似文献   

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目的对比高血压脑出血三种手术方式的疗效。方法研究对象为2013-02—2015-05我院收治的126例高血压脑出血患者,依据入院顺序分为甲组、乙组、丙组各42例,甲组实施去骨瓣开颅术,乙组实施小骨窗开颅术,丙组实施微创穿刺清除术,观察3组手术相关指标(术中出血量、住院时间、手术时间)、临床疗效及术后并发症发生情况。结果丙组术中出血量明显少于甲组、乙组,住院时间及手术时间明显短于甲组、乙组,差异均有统计学意义(P0.05);乙组术中出血量明显少甲组,住院时间、手术时间均明显短于甲组,差异均有统计学意义(P0.05);术后丙组总有效率90.48%,较甲组的52.38%、乙组的73.81%明显提高,乙组术后总有效率较甲组显著提高,差异均有统计学意义(P0.05);3组术后并发症发生率比较无明显差异(P0.05)。结论高血压脑出血三种手术方式的疗效差异明显,微创穿刺清除术手术相关指标及临床疗效较去骨瓣开颅术、小骨窗开颅术有明显优势。  相似文献   

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目的 观察微创穿刺血肿清除术治疗急性脑出血的临床疗效.方法 72例急性脑出血患者随机分为观察组36例和对照组36例.对照组行小骨瓣开颅血肿清除术,观察组行微创穿刺血肿清除术治疗.评价2组临床治疗效果、治疗前后NIHSS与ADL评分,同时观察2组术后1个月内的再出血率.结果 观察组总有效率86.11%,对照组为83.34% (P>0.05).观察组平均NIHSS、ADL评分均低于对照组(P<0.05).术后1个月内观察组再出血率8.33%,对照组为16.67%(P<0.05).结论 微创穿刺血肿清除术治疗急性脑出血的临床疗效优于传统小骨瓣开颅血肿清除术.  相似文献   

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目的探讨神经导航辅助微创穿刺血肿引流术(NAMIEH)、小骨窗开颅血肿清除术(SWCEH)与大骨瓣开颅血肿清除术(LBFEH)治疗高血压性脑出血的疗效及术后再出血影响因素Logistic回归分析。 方法回顾性分析自2016年9月至2019年3月解放军联勤保障部队第九一医院神经外科收治的134例高血压性脑出血患者的临床资料,根据手术治疗方式的不同将其分为NAMIEH组38例、SWCEH组45例与LBFEH组51例。记录2组患者术前及术后7、14 d出血量、GCS评分、NIHSS评分、Barthel指数以及治疗后临床疗效并进行比较,并将高血压性脑出血患者术后再出血影响因素采用Logistic回归分析。 结果3组患者术前出血量、GCS评分、NIHSS评分及Barthel指数比较,差异无统计学意义(P>0.05);3组患者术后7、14 d出血量、GCS评分、NIHSS评分及Barthel指数比较,差异均有统计学意义(P<0.05);3组患者术前及术后7、14 d出血量及NIHSS评分均依次明显降低,GCS评分及Barthel指数均依次明显升高,且组内任意两时间点比较差异均有统计学意义(P<0.05)。NAMIEH组、SWCEH组再出血、血肿残留及并发症发生率均分别明显低于LBFEH组,NAMIEH组再出血发生率(10.53%)、血肿残留发生率(5.26%)及术后并发症发生率(15.79%)均明显低于SWCEH组(P<0.05)。以高血压性脑出血患者术后再出血为因变量,对单因素分析中的可能术后再出血影响因素进行Logistic回归分析,结果显示合并糖尿病、术前收缩压、发病至手术时间、血肿形状、破入脑室、术前出血量、术前GCS评分、术前NIHSS评分、术前Barthel指数、凝血功能异常、术后并发症及总住院时间为高血压性脑出血患者术后再出血的独立影响因素(均P<0.05)。 结论NAMIEH治疗高血压性脑出血的临床效果明显优于SWCEH及LBFEH,可有效促进神经功能的恢复,明显降低再出血及术后并发症的发生率,且合并糖尿病、术前收缩压、发病至手术时间等为高血压性脑出血患者术后再出血的独立影响因素。  相似文献   

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目的分析高血压脑出血患者小骨窗开颅的治疗效果。方法对我院收治的40例高血压脑出血患者进行小骨窗开颅术血肿清除治疗,手术完成后4周对所有患者进行Glasgow预后评估,统计分析患者恢复和并发症情况。结果所有患者均成功进行手术,无术中死亡病例,术后17例持续高血压,11例发生消化道出血,9例发生肺部感染或泌尿系统感染,2例复发脑出血后死亡。结论小骨窗开颅术治疗高血压脑出血多数患者预后较好,但应注意围手术期的抗感染治疗。  相似文献   

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目的 探讨小骨窗开颅血肿清除术在高血压基底节区脑出血病人中的应用和疗效。方法 回顾性分析我院采取小 骨窗开颅血肿清除术治疗326例高血压基底节区脑出血患者,意识状况分级:Ⅰ级27例,Ⅱ级130例,Ⅲ级116例,Ⅳ级49例; 发病至手术时间6h内208例,6-24h内84例,24-72h以内34例;均行以OM线为基线的头颅CT扫描,利用CT提供的三维数 据在头颅标出血肿中心投影点,以此点为中心做颞部头皮直切口,颅骨钻孔,切开硬膜和皮层,直视下清除脑内血肿。结果 本 组术后血肿基本消失214例,残留10ml以下72例,残留20ml以下32例,残留30ml以下8例。本组无术中死亡病例,22例死于 术后并发症。有287例随访6-18月,按ADL分级:Ⅰ级51例,Ⅱ级93例,Ⅲ级107例,Ⅳ级31例,Ⅴ级5例。其恢复情况优 于综合文献,效果较满意。结论 小骨窗开颅血肿清除术用于高血压基底节区脑出血较之成型骨辩开颅迅速,创伤小;与血肿穿 刺抽吸术相比,可在直视下血肿腔内操作,避免损伤周围正常脑组织,清除血肿较彻底,止血充分,符合微创手术要求;可早期 解除脑压迫,减少继发损害,利于康复,改善生存质量;手术操作简便,易于推广。  相似文献   

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A number of cross-sectional population studies have shown that a strong sense of coherence (SOC) is associated with various aspects of good perceived health. The association does not seem to be entirely attributable to underlying associations of SOC with other variables, such as age or level of education. OBJECTIVE: The aim of the study reported here was to determine whether SOC predicted subjective state of health. METHODS: The study was carried out as a two-way panel mail survey of 1976 individuals with 4 years interval for two collections of data. The statistical method used was multivariate cumulative logistic modeling. Age, initial subjective state of health, initial occupational training level, and initial degree of social integration were included as potential explanatory variables. RESULTS: A strong SOC predicted good health in women and men. CONCLUSIONS: SOC can be interpreted as an autonomous internal resource contributing to a favorable development of subjective state of health. SOC data should, however, be regarded as complementary to and not a substitute for information already known to be associated with increased risk of future ill health.  相似文献   

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Tubocurarine (Tc) effect on membrane currents elicited by acetylcholine (ACh) was studied in isolated superior cervical ganglion neurons of rat using patch-clamp method in the whole-cell recording mode. The "use-dependent" block of ACh current by Tc was revealed in the experiments with ACh applications, indicating that Tc blocked the channels opened by ACh. Mean lifetime of Tc-open channel complex, tau, was found to be 9.8 +/- 0.5 s (n = 7) at -50 mV and 20-24 degrees C. tau exponentially increased with membrane hyperpolarization (e-fold change in tau corresponded to the membrane potential shift by 61 mV). Inhibition of the ACh-induced current by Tc (3-30 microM/1) was completely abolished by membrane depolarization to the level of 80-100 mV. Inhibition of ACh-induced current was augmented at increased ACh doses. It is concluded that the open channel block produced by Tc is likely to be the only mechanism for Tc action on nicotinic acetylcholine receptors in superior cervical ganglion neurons of rat.  相似文献   

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Fine structural characteristics of synapses in the spiral organ of Corti were examined, with reference to differences between inner and outer haircell systems, and to location of neurons of origin of efferent axons. Surgical interruption of crossed olivocochlear bundle, of vestibular nerve, of facial nerve, and excision of superior cervical ganglia were used to determine the pathways of efferent axons. Interruption of the vestibular nerve near the brainstem results in degeneration of all efferent terminals on outer hair cells. Mid-line lesions at, and caudal to, the facial colliculus result in degeneration of about half of these efferent terminals. Efferent synaptic bulbs to the inner hair-cell system are small, of the order of one micron, and form type 2 junctions with afferent dendrites. They tend to have more large dense-core vesicles (about 80 nm) than the large efferent terminals of the outer hair-cell system, and appear to be the terminals of axons in the habenula perforata, which exhibit varicosities laden with large dense core vesicles. The varicosities are unaffected by excision of the superior cervical ganglia. So far as our material can reveal, it appears that the varicosities in the habenula perforata do not survive vestibular root interruption, nor do the efferent processes in the internal spiral bundle or at the base of inner hair cells. Most interestingly, the afferent processes of the inner hair-cell system, as identified for example by their relation to pre-synaptic bodies in the inner hair cells, are subject to a trans-synaptic reaction after severance of the vestibular root. They undergo a dramatic cytological transformation, characterized by increase of volume, engorgement with microtubules, microfilaments, microvesicles of various sizes, and clusters of lysosomes. Thus, both the efferent and afferent terminals of the inner hair-cell system show marked cytological differences from the corresponding terminals of the outer hair cell system.  相似文献   

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Background Dementia occurs in the majority of patients with Parkinson’s disease (PD). Late onset of PD has been reported to be associated with a higher risk for dementia. However, age at onset (AAO) and age at baseline assessment are often correlated. The aim of this study was to explore whether AAO of PD symptoms is a risk factor for dementia independent of the general effect of age. Methods Two community-based studies of PD in New York (n = 281) and Rogaland county, Norway (n = 227) and two population-based groups of healthy elderly from New York (n = 180) and Odense, Denmark (n = 2414) were followed prospectively for 3–4 years and assessed for dementia according to DSM-IIIR. All PD and control cases underwent neurological examination and were followed with neurological and neuropsychological assessments. We used Cox proportional hazards regression based on three different time scales to explore the effect of AAO of PD on risk of dementia, adjusting for age at baseline and other demographic and clinical variables. Findings In both PD groups and in the pooled analyses, there was a significant effect of age at baseline assessment on the time to develop dementia, but there was no effect of AAO independent of age itself. Consistent with these results, there was no increased relative effect of age on the time to develop dementia in PD cases compared with controls. Interpretation This study shows that it is the general effect of age, rather than AAO that is associated with incident dementia in subjects with PD. Received in revised form: 22 December 2005  相似文献   

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After a hopeful beginning, the social process of the reintegration of those with severe mental illness has come to a standstill. I am led to wonder whether "the community" really wants to live together with people suffering from severe mental illness, and if so, how closely? As long as the medical treatment of mental illness provided by the general practitioners is fundamentally deficient, as they are not able to prescribe the necessary interventions--such as out-patient psychiatric nursing, and service providers in the out-patient sector are content with offering increasingly intensive forms of care for the less seriously ill at the cost of the Social Welfare System--the reintegration of those with serious mental illness remains an illusion--which is mainly to the benefit of providers of residential care in homes and hostels.  相似文献   

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