首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 140 毫秒
1.
简易智能精神状态检查量表检测老年期痴呆患者的应用探讨   总被引:20,自引:1,他引:19  
目的 研究简易智能精神状态检查量表(mini-mental state examination。MMSE)的人群分布特征、临床适用性、痴呆筛查的界定值及痴呆早中期的分界值。方法 采用随机分层抽样方式。对北京城乡40岁及以上常模、痴呆及易混淆疾病人群进行MMSE调查研究及统计分析。结果 MMSE检测结果表明.在城乡常模人群间差异有显著性。其分值随年龄增长而下降.文化程度越高分值越高;痴呆筛查的界定值文盲组≤24分、文化组(初小及以上)≤26分.痴呆早中期分界值文盲组为17分、文化组(初小及以上)为19分。结论 MMSE涵盖的认知项目广泛。操作简单方便。筛查痴呆敏感度较高。适于临床广泛应用,但MMSE判断的认知功能下降是非特异性的.受许多疾病及意识、精神状态干扰,故应结合临床综合判断。  相似文献   

2.
上海城乡55岁以上居民认知功能筛查分析   总被引:24,自引:0,他引:24  
目的 了解上海城乡 5 5岁及以上居民简易智能筛查量表 (mini mentalstateexamination ,MMSE)分布特征 ,为制定合适的MMSE筛查分界值提供科学依据。方法 对上海市 10个区 (县 )居民采用分层多级整群抽样方法确定调查对象 ,抽样单位中的全部 5 5岁及以上符合入选条件的居民共 170 18。调查采取二阶段法。结果 完成测试的 15 90 4名居民MMSE分布 ,结果显示各教育程度及各年龄段的第 10百分位数和均值比国内其他报道高出 1~ 2分 ,MMSE分界值 60岁第10个百分位数文盲组≤ 2 1分、小学组≤ 2 5分、初中及以上组≤ 2 8分。影响MMSE得分的因素依次为教育 ,年龄和性别 ,受高等教育的居民MMSE测试成绩在不同年龄、性别和城乡间的差别较小 ,教育程度对上海城、乡居民MMSE影响的差异( 0 99和 1 5 6)较北京小 ( 0 89和 2 0 8)。结论 MMSE得分是判断认知功能是否正常的非特异性指标 ,MMSE分界值标准的选择需根据情况作适当的调整 ,有助于早期发现痴呆病人 ,减少漏诊。  相似文献   

3.
对97例脑梗塞后痴呆的危险因素分析   总被引:1,自引:0,他引:1  
目的 探讨脑梗塞后血管性痴呆(VD)的发生率及其危险因素。方法 采用简易智力状态检查表(MMSE)和流调用抑郁自评量表(CES-D);对97例住院脑便塞病人进行筛选与检测。对其中认知受损者则采用日常生活能力量表(ADL)和Hachincki缺血指数量表(HIS)进上步检测。并对痴呆组5和非痴呆组病人的临床资料进行统计分析。结果 (1)27例确诊为VD,VD发生率为27.84%,≥65岁为34.33  相似文献   

4.
痴呆患者423例MMSE和BBS测试结果分析   总被引:18,自引:0,他引:18  
为了深入探讨智能的亚项及其影响因素,对临床诊断为痴呆的423例患者进行了简易精神状态检查表(MMSE)和Blesed行为量表(BBS)的测试,应用多元回归分析、相关分析及t检验对测试结果进行了智能亚项及其影响因素的深入分析。结果显示:文化程度与MMSE总分及其4个智能亚项(认知、记忆、语言、运用和视空间技能)和BBS总分均有密切关系(P<0.001);MMSE总分及其4个智能亚项和BBS总分各项之间均密切相关(P<0.001);轻度和中度痴呆患者两组间各智能亚项差异显著(P<0.001)。结论:MMSE和BBS结合使用是评价痴呆的好方法。各智能亚项均能反映痴呆的程度。文化程度为影响痴呆患者智能的最主要的和独立的因素。  相似文献   

5.
HDS、MMSE、BBS在痴呆筛查中的应用   总被引:9,自引:0,他引:9  
目的:评价长谷川痴呆量表(HDS)、简易精神状态检查表(MMSE)、Blessed行为量表(BBS)3种量表在痴呆筛查中的可行性。方法:对50例50岁以上可疑智能减退的患者进行HDS、MMSE、BBS测试,并对其智能水平独立做出判断,比较3种量表在痴呆筛查中的有效性及优缺点。结果:3种量表得分在痴呆组和非痴呆组之间有显著差异,HDS、MMSE、BBS的敏感性分别为66.67%、80%、93.33%。特异性分别为100%、85.71%、28.57%。痴呆和非痴呆患者相比较在时间定向力、记忆、计算、视空间等方面损害较重,而命名相对保存。结论:3种量表中,MMSE敏感性、特异性均较好,HDS特异性最好,而BBS在排除痴呆诊断中意义较大。主观测试与客观评价结合是全面评估智能水平的有效途径。因简易量表得分受多种因素影响,更适用于大样本试验。  相似文献   

6.
社区老年期痴呆的发病率及相关因素研究   总被引:6,自引:0,他引:6  
目的 了解社区老年期痴呆的发病率及相关因素。方法 以1992年上海县8个乡(镇)老年期痴呆患病率调查时的1515例样本对象(按整群分层随机抽样方法抽出的实访样本数),4.5年后进行老年性痴呆的发病率调查,并对初筛中MMSE分值较低者226人作载脂蛋白E基因分型。结果在55岁以上老年人群中,痴呆的年发病率为0.53%,其中AD的年发病率为0.34%,VD(血管性痴呆)为0.15%,其它痴呆为0.04  相似文献   

7.
茴拉西坦治疗62例Alzheimer′s病的临床疗效   总被引:1,自引:0,他引:1  
伍毅  高之旭 《上海精神医学》1997,9(A00):227-228
目的 观察茴拉西坦片剂治疗62例Alzeimer′s病的临床疗效,方法 茴拉西坦200mg~300mg,po,tid疗程2日。结果 总有效率72.58%,其中轻度痴呆90%,中度痴呆为66.29%,各量表治疗前后平均分值均有显著差异,(P〈0.01),其中HDS-R,MMSE,ADL治疗前事各提高约4.5分WAIS和WMS分别提高5.8分和10分。治疗中仅有轻度口干,便泌,嗜睡副反应,能自行消失,  相似文献   

8.
何燕玲  张明园 《上海精神医学》2001,13(B12):23-25,40
目的 探索高龄老人认知功能的动态变化规律和相关因素,以及在痴呆诊断中的意义。方法 随访75岁以上非痴呆社区老人9年,分别在基础时,4年后和9年后用简易痴呆筛查量表(BSSD)检查认知功能,并根据DSM-Ⅲ-R做痴呆诊断,资料完整者共122例。结果 1.BSSD总均分在9年中的下降呈加速趋势,非痴呆组的下降幅度有限,痴呆组的下降幅度明显,且呈突然快速下降;2.各检测阶段得分均为非痴呆组高于痴呆组;3.BSSD得分女性低于男性,低教育程度低于高教育程序;4.BSSD以19/20分作为分界值诊断痴呆的敏感性91.0%,特异性70.5%。结论 痴呆的认知功能呈病理性衰退特点;BSSD对识别痴呆和早期筛查有用。  相似文献   

9.
脑血管性痴呆局部脑血流的定量分析   总被引:12,自引:0,他引:12  
目的探讨血管性痴呆的脑循环变化。方法采用单光子发射计算机断层显像(SPECT),99m-ECD标记,定量测定血管性痴呆(VD)、多发性脑梗塞(MI)及正常老年人各10例的局部脑血流量。结果VD组各脑叶及基底节区平均脑血流量均显著低于对照组(P<0.01);VD组比MI组额颞叶皮质血流量明显减少(P<0.01,P<0.05);VD额叶皮质脑血流量改变与神经心理测试MMSE呈正相关(r=0.692,P<0.05)。结论VD存在全脑广泛的脑血流灌注降低。额叶皮质血流灌注降低与痴呆的发生及痴呆的严重程度密切相关。SPECT局部脑血流定量测定对于VD的预测及早期发现有重要意义  相似文献   

10.
用放射免疫法测定了30例多发梗塞性痴呆(MID)、35例无痴呆多发脑梗塞患者(MCI)及30名健康人的血浆生长抑素(SS)、精氨酸加压素(AVP)及β-内啡肽(β-EP)含量,同时测定了部分MID和MCI患者脑脊液(CSF)中SS、AVP、β-EP含量。发现MID患者血浆SS、AVP含量比MCI组和健康对照组均降低(P<0.05),且随痴呆程度的加重,其含量有递减趋势。而血浆中β-EP在这三组间差异无显著性意义(P>0.05)。MID组CSF中SS、β-EP含量低于MCI组(P<0.05),而CSF中AVP含量在两组间无差异(P>0.05),CSF中AVP含量与痴呆的关系有待进一步研究。  相似文献   

11.
BACKGROUND AND PURPOSE: The Short-Memory Questionnaire (SMQ) developed by Koss et al. is a standardized, validated reliable informant-based scale to assess everyday memory problems. In the previous study, we prepared its Japanese version and validated the reliability in assessing patients with Alzheimer Disease. In the present study, we examined the relations between the performance evaluated by the Japanese version of the SMQ combined with the Mini-Mental State Examination (MMSE) and demographic variables (age, sex, and education). SUBJECTS AND METHODS: Subjects were a total of 613 elderly healthy individuals living in the rural residency of Nakayama, Japan. They consisted of 287 males and 326 females and ranged from 65 to 94 years in age and from 0 to 16 years in education. The MMSE was conducted by neuropsychiatrists to assess the severity of cognitive impairment, and the SMQ was conducted by public health nurses, who asked a family member of each subject. The effects of age, sex and education on the MMSE and SMQ scores were analyzed by analysis of variance (ANOVA) using post-hoc Scheffé test. RESULTS: The mean MMSE and SMQ scores (+/- SD) were 27.6 (+/- 2.5) and 44.5 (+/- 2.1), respectively. The post-hoc Scheffé test revealed significantly higher MMSE scores for individuals with 8 years or more in education than for those with less than 8 education years. Between males, no significant differences were observed in MMSE score; however, among females, significantly higher scores were noted in those aged 69 or younger than in those aged 70-74 or those aged 80 or older. Of individuals aged 80 or older, males showed significantly higher scores than females, whereas no significant differences were observed between sex in other age groups. As to the SMQ, higher scores were shown by persons with longer education years and by females than males. CONCLUSION: Low MMSE scores were related to low education level and older females. Low SMQ scores were not related to aging, but linked to low education level and males. Both the MMSE and SMQ, which can be easily administered, are affected by education years and sex. In addition, MMSE score depends on age. Therefore, careful consideration should be paid to age, education level and sex for future execution of the MMSE and SMQ.  相似文献   

12.
目的:调查拉萨市区藏族中老年人简易精神状态检查结果分布状态。方法:以拉萨市区55岁及以上藏族人群3776名作为调查对象。采用深入到居民区集中和家访相结合的普查方法。利用简易精神状态检查量表(MMSE)、日学活动功能量表(ADL)进行面对面问卷及配合必要的其他检查等。结果:中老年人MMSE结果低于分界值分布率为7.2%,其中男性为9.3%,女性为6.3%。结论:拉萨市区中老年人MMSE结果低于分界值分布率结果与国内其他市区报道大致相似,但在年龄、教育程度、性别等分布上有其不同点,可能与西藏特殊的地理环境、生活习惯和历史文化风俗有关。  相似文献   

13.
This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy, perceived social support and subjective well-being. From January to February 2022, 620 participants (320 rural and 300 urban residents) from three provinces of China were selected by convenience sampling. A general data questionnaire, mental health literacy scale, perceived social support scale and subjective well-being scale were administered. The mental health literacy scores of urban residents were 3.34 ± 0.57 and those of rural residents were 2.73 ± 0.79. The results of multiple regression analysis showed that the mental health literacy scores of rural residents were more significant than those of urban residents in terms of sex and age, while urban residents’ mental health literacy scores were more significant than those of rural residents in terms of monthly income. Mental health literacy, perceived social support and subjective well-being of young and middle-aged urban and rural residents were all positively correlated (P < 0.01). While the level of mental health literacy is better among urban residents than rural residents, perceived social support plays a partial mediating role between mental health literacy and subjective well-being of both urban and rural residents, and should be the focus of researchers seeking to improve the level of well-being of residents.  相似文献   

14.
The Mini-Mental State Examination (MMSE), a brief test to assess cognitive status, is heavily influenced by age and education. It was administered to 1019 elderly subjects (aged 65–89 years) living in three different Italian cities. A statistical non-linear regression model was built up in order to obtain adjustment coefficients to reduce the influence of demographic variables on the MMSE raw scores. Age and educational level were significantly and independently associated with the MMSE score. Results of a multiple linear regression with transformation of age and education provided adjustment coefficients of the MMSE raw scores. Data from this study will ameliorate the overall reliability of MMSE as a screening test for cognitive impairment in elderly people.  相似文献   

15.
Norms for the Mini-Mental State Examination in a healthy population.   总被引:7,自引:0,他引:7  
BACKGROUND: Although the Mini-Mental State Examination (MMSE) is widely used in clinical practice, few norms exist for healthy populations covering a broad range of ages. OBJECTIVE: To obtain MMSE norms specific for age, gender, and education in healthy adults. METHODS: From the population registers of seven communities across Italy, we selected a proportionate random sample of residents age 20 to 79 years to evaluate their health status with respect to conditions affecting cognitive performance. This sample yielded 908 persons who were deemed to be without cognitive impairment and who were then given the MMSE. We calculated fifth percentile norms and presented them as step functions. We then validated the norms as a screening tool for dementia in persons age 65 to 79 years. The validation was based on unpublished data from a separate study and involved estimates of sensitivity and specificity. RESULTS: The norms declined with advancing age, especially for less educated women. Given any age and sex, the norms were higher for individuals with higher educational levels. In screening for dementia, the norms had a sensitivity of 85% and a specificity of 89%. CONCLUSIONS: When using MMSE scores, it is important to account for age, gender, and education, especially in populations where the educational level is low. Expressing MMSE norms as step functions provides an easy-to-use tool for neurologists and other clinicians.  相似文献   

16.
A culturally relevant form the Mini-Mental State Examination was administered to 502 persons aged 60 years and over living in three locations representing rural and urban settings in southwestern Nigeria. Multivariate statistical methods show that variables like sex, age, education and self-assessed health affect the scores on MMSE. The coefficient alpha for the instrument was low for those with less than complete primary education, but for those with full primary education or more, it gave a value similar to those obtained in some studies in western countries.  相似文献   

17.
上海城乡帕金森病患病率研究   总被引:5,自引:0,他引:5  
目的 :明确我国老年人口中帕金森病的患病率以及观察帕金森病的动态变化。方法 :抽样方法采用分层多级整群抽样方法确定调查对象。抽样结果为 2 2个居委会和 14个村委会的 5 5岁和以上的居民 170 18。调查采用二阶段法。采用统一调查表和标准化调查用语 ,按名单入户调查。结果 :实查 16 0 30人 ,拒查等失访 988人 ,实查率 94.2 % ,总的粗患病率为 0 .99% ,6 0岁或以上、 6 5岁或以上 PD患病率分别为 1.13%和 1.42 % ,其中男性患病率为 0 .86 % ,女性患病率为 1.1% ,城市患病率为 1.1% ,农村患病率为 0 .76 %。 PD患病率随年龄的增长而增加 ,到 85岁下降。男女有相似的趋势。帕金森病综合征以血管性的帕金森综合征最多。结论 :上海帕金森病患病率高于以往的调查 ,和 10年前相比有上升趋势  相似文献   

18.
Age-specific norms for the Mini-Mental State Exam   总被引:3,自引:0,他引:3  
We administered the Mini-Mental State Exam (MMSE) to 194 healthy men and women, ages 40 to 89 years. Total score was significantly associated with age (p less than 0.0001), but not vocabulary, education, Beck's Depression Inventory Score, or sex. The lowest quartile cutoff scores for the MMSE by decade were 40s - 29; 50s - 28; 60s - 28; 70s - 28; and 80s - 26. When screening for progressive decline in cognitive performance, the use of age-specific norms may provide greater sensitivity than the present recommended cutoff score of less than 24.  相似文献   

19.
OBJECTIVE: This article examines the influence of sociodemographic, biological, and health variables on Mini-Mental State Exam (MMSE) performance, and assesses how the diversity of the population should be reflected in the MMSE cutoff scores used for screening. METHODS: The sociodemographic profiles and MMSE scores of adults aged 65-years and over who participated in the Australian National Mental Health and Well-being Survey were assessed (N = 1,792). RESULTS: The regression models showed that older age, education levels, language spoken at home and in country of birth, socioeconomic status (SES), occupation, sex, and presence of a mood disorder made significant and unique contributions to performance on the MMSE. The individual (univariate) influence of each factor ranged from -2.61 to 0.09 points, with non-English speaking background (NESB) making the biggest impact. Based on a MMSE score of < or =23 points, 7.7% of the Australian elderly population screened positive for cognitive impairment that may be indicative of dementia. In those scoring < or =23 points, the multivariate model accounted for 24.61% of the variance. CONCLUSION: Many sociodemographic variables and the presence of a mood disorder influence MMSE performance. Using conventional cutoff scores for screening will lead to a high rate of false positives in older adults (75+ years), those with NESB, and those with low SES, and is insensitive for those with high education. The authors suggest simple rules for the correction of the impact of these variables.  相似文献   

20.
An epidemiological survey of age-related dementia in an urban area of Beijing   总被引:12,自引:0,他引:12  
An epidemiological survey of age-related dementia among community residents of an urban of Beijing was conducted in 1986. Initial screening of 1331 subjects aged 60 and above was made using the Mini-Mental State Examination (MMSE) with a cutoff point of 17. All suspected cases of dementia and 5.5% of all others were then given a full clinical examination, with subjects being diagnosed and classified according to DSM-III criteria. The MMSE was found to have satisfactory sensitivity, although scores were significantly correlated with education. Prevalence rates of moderate and severe dementia were 1.28% for those aged 60 and above and 1.82% for those aged 65 and above. Rates for multi-infarct dementia were higher than those for primary degenerative dementia; females had higher rates than males and rates increased sharply with age. All the dementia cases were cared for in their own homes, by relatives. There is a need for increased knowledge and services for elderly people in the community.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号