太白蓼挥发油的化学成分和抗菌实验初步研究

目的：研究太白蓼挥发油的化学成分及其抗菌活性。方法：采用水蒸气蒸馏的方法提取太白蓼挥发油，运用气相色谱-质谱联用技术（GC—MS）对其化学成分进行鉴定并对该挥发油的抗菌活性（MIC and MBC）进行了测定。结果：通过NIST质谱库检索，鉴定了其中的13个化合物，运用峰面积归一法确定各个组分的含量，药理实验表明太白蓼挥发油对所选取得8种菌株均有很好的活性。结论：太白蓼的挥发油具有抗菌作用。     

Chemical composition,antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha Boiss. and Heldr. (var. erythrantha and var. cedretorum P.H. Davis) endemic in Turkey

In the present study, chemical compositions, antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha var. erythrantha (SE) and Sideritis erythrantha var. cedretorum (SC), which are endemic taxa in Turkey, were investigated. The essential oils obtained by hydrodistillation were analyzed by gas chromatography–mass spectrometry (GC–MS). α-Pinene was the major component of the essential oils of SC and SE. SC essential oil was as effective as antibiotic against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant Enterococcus faecalis (VRE), ampicillin resistant Haemophilusinfluenzae and vancomycin sensitive E. faecalis. Similarly, SE essential oil was also as effective as antibiotic against VRE and ampicillin resistant H. influenzae. Antioxidant activities of the essential oils of SC and SE were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH), β-carotene/linoleic acid and reducing power. Both essential oils exhibited weak antioxidant activity. This is the first report on antimicrobial and antioxidant activities of the essential oils of SC and SE.