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1.
目的 探讨实时虚拟超声成像系统(real-time virtual sonography systen,RVS)与钼靶X线成像(molybdenum X-ray photography,MX-rP)对良恶性乳腺病灶的鉴别诊断.方法 对83例女性乳腺肿块患者共101个病灶术前行RVS与MX-rP检查,手术病理为诊断金标准,分析RVS与MX-rP诊断乳腺疾病的准确性.结果 RVS诊断乳腺恶性病变的敏感性、特异性、准确性、阳性和阴性预测值分别为87.06%,93.05%,91.08%,94.36%,80.01%.MX-rP诊断乳腺恶性病变的敏感性、特异性、准确性、阳性和阴性预测值分别为72.4%,83.33%,80.19%,89.55%和63.52%, RVS诊断准确性高于MX-rP(P<0.05),结论 RVS在诊断乳房良恶性病灶时较MX-rP有更高的准确性,两者结合可以提高乳腺良恶性病灶诊断的准确性.  相似文献   

2.
目的:探讨超声弹性成像(UE)与彩色多普勒超声在乳腺良恶性占位病变诊断中的价值。方法:选择乳腺占位性病变的女性患者195例,共234个病灶,所有病灶均行彩色多普勒超声检查及UE检查,并以病理检查为金标准,比较彩色多普勒超声检查及UE对病灶良、恶性诊断的敏感性、特异性及准确性。结果:共有234个乳腺占位性病灶,病理诊断为良性病灶146个,恶性病灶88个。UE、CDFI血流分级、RI、CDFI血流分级联合RI对恶性占位性病灶诊断敏感性、特异性性、准确性分别为(87.5%、95.2%、92.3%)、(69.3%、71.9%、75.2%)、(76.5%、62.2%、68.7%)、(55.7%、84.9%、73.9%);UE诊断正确病灶数为216个,误诊病灶18个,而CDFI血流分级联合RI正确诊断病灶数为173个,误诊病灶61个,UE诊断乳腺良恶性病灶准确性高于彩色多普勒超声(P<0.05)。结论:UE对乳腺占位性病变的良恶性诊断的敏感性、特异性、准确性高于多普勒超声,但也存在一定的误诊率。因此,联合其他影像学检查可进一步提高UE对乳腺占位性病灶良恶性的诊断准确率。  相似文献   

3.
目的 探讨超声实时应变成像技术(量化超声弹性成像技术)诊断乳腺病变良、恶性的最佳诊断界点及其诊断价值.方法 分析经手术病理证实的83例不同病理类型良恶性乳腺结节的弹性成像检查结果,根据恶性肿瘤的特点,对病灶整体硬度比(病灶整体与正常腺体组织比值)与局部硬度比(病灶局部(1cm2)最高值-病灶局部最低值)进行量化分析;通过受试者工作特征( ROC)曲线了解该技术对乳腺疾病性质鉴别诊断的价值.结果病灶整体硬度比值对乳腺病灶良、恶性诊断ROC曲线下面积为0.926,其敏感性、特异性、阳性预测值、阴性预测值及准确性分别为:81.30%、92.20%、93.75%、92.15%和92.55%.病灶局部硬度比值对乳腺病灶良、恶性诊断的ROC曲线下面积为0.939,其敏感性、特异性、阳性预测值、阴性预测值及准确性分别为:90.60%、96.10%、96.87%、94.08%和95.18%.结论 超声实时应变成像技术使用更为简便、客观、准确,有助于乳腺肿块的良、恶性鉴别.  相似文献   

4.
目的:探讨弹性成像(UE)、弹性应变率比值法(SR)与钼靶X线(molybdenum X-ray photography,MX-rP)在乳腺癌诊断中的价值。方法:对114例患者,139个病灶术前行UE,SR与MX-rP检查,以手术病理为诊断金标准,分析在病灶诊断、病灶周围浸润、腋窝转移淋巴结等方面,UE、SR与MX-rP的诊断价值。结果:SR和MX-rP诊断乳腺恶性病灶的敏感性、特异性、准确性分别为90%、95.4%、94.2%和66.7%、80.7%、77.6%,两者差异有统计学意义(P<0.05);SR和MX-rP的受试者工作特征曲线下面积(AUC)分别为0.935和0.803,两者比较差异有统计学意义(P<0.05);常规超声、弹性成像对转移性淋巴结的检出率高于钼靶X线(P<0.05);弹性成像对病灶病理测值的符合度较常规超声高(P<0.05)。结论:常规超声、弹性成像联合钼靶X线可以进一步提高乳腺恶性肿块的检出率。  相似文献   

5.
目的探讨彩色多普勒血流显像(CDFI)与实性弹性组织成像(URTE)对乳腺实性病灶良恶性鉴别诊断的价值。方法对经病理证实的260例患者373个乳腺实性病灶,在高频超声检出病灶后,对病灶进行CDFI与URTE检查前瞻性研究。病灶的血流分级采用Adler半定量法;URTE评分采用改良5分法。结果 CDFI对乳腺病灶良恶性鉴别诊断的敏感性85.7%、特异性74.4%、准确性77.0%、阳性预测值49.3%、阴性预测值94.7%、约登指数0.6。而URTE的敏感性83.3%、特异性93.8%、准确性91.4%、阳性预测值79.6%、阴性预测值95.1%、约登指数0.8。结论 URTE在诊断特异性、准确性和阳性预测值方面较CDFI有明显的优势,反映诊断试验真实性的综合指标约登指数也优于CDFI。URTE应和CDFI一样作为临床鉴别乳腺实性病灶良恶性的重要影像技术手段。  相似文献   

6.
目的观察分析乳腺MR动态增强扫描联合扩散加权成像的临床应用。方法分析高州市人民医院22例乳腺病变患者乳腺病灶时间-信号强度曲线情况,比较动态增强扫描、扩散加权成像及两者相联合的诊断结果。结果动态增强扫描联合扩散加权成像用于诊断乳腺病变的敏感性(95.2%)、特异性(90.1%)、准确性(93.8%)、阳性预测值(96.2%)及阴性预测值(90.1%)均显著高于MRI诊断和DWI诊断。应用动态增强扫描联合扩散加权成像诊断乳腺良恶性病灶的敏感性、特异性和准确性均高于二者分别用于诊断的情况。结论动态增强扫描联合扩散加权成像技术用于乳腺病变的诊断不仅可相互弥补因平台期和ADO重叠部分带来的不足,还可照单一的诊断形式提高诊断的敏感性、特异性和准确性,为乳腺良、恶性病灶的诊断提供了更为有力的依据。  相似文献   

7.
目的:比较超声弹性成像与乳腺钼靶X线检查在乳腺病变诊断中的应用价值。方法:搜集乳腺外科就诊的95例患者的128个病灶,行常规超声检查、弹性成像检查及钼靶X线检查,根据美国放射学会的BI-RADS诊断标准进行分级,分别与病理结果对照分析,分析比较其敏感性、特异性、准确性,评价诊断效果。结果:在乳腺病变诊断中,超声弹性成像的敏感性为91.89%,特异性为85.71%,准确性87.50%,阳性预测值和阴性预测值分别为72.34%和96.30%;乳腺钼靶X线检查的敏感性为62.16%、特异性为82.42%、准确性为76.56%,阳性预测值和阴性预测值分别为58.97%和84.27%。弹性成像检查的准确率高于乳腺钼靶X线检查,两者比较存在显著性差异(P<0.05)。结论:超声弹性成像在诊断乳腺病变时较钼靶X线更有价值。  相似文献   

8.
黄巧燕  蔡石兰  黄毅锋 《广西医学》2012,34(7):895-896,904
目的 比较超声弹性成像(UE)比值法与Itoh 5分评分法对乳腺实性肿块良恶性的诊断价值.方法 应用UE比值法与Itoh 5分评分法对44例患者共49个乳腺肿块分别进行检查,结果 与病理对照.结果 UE比值法诊断乳腺病灶良恶性的敏感性、特异性、准确性分别为87.50%、93.94%、91.47%,Itoh 5分评分法分别为68.75%、78.79%、75.51%.结论 UE比值法对乳腺肿物的诊断价值优于Itoh 5分评分法,为UE检查提供一有价值的、更为客观的诊断标准.  相似文献   

9.
目的 探讨自动乳腺全容积成像技术(ABVS)对乳腺导管内乳头状瘤(IDP)的诊断价值。方法 研究对象为2010年8月至12月在北京协和医院行乳腺病变切除活检的213例患者,共239个乳腺病变,均获得手术病理结果。以病理诊断为金标准,计算并比较ABVS和常规超声对IDP的诊断效力。结果 239个病变中,病理证实良性154个,恶性85个,其中IDP病变26个。ABVS共发现41个(17.2%)病灶符合IDP诊断标准,诊断敏感性、特异性、阳性预测值、阴性预测值、准确性分别为88.5%、91.5%、56.1%、98.5%、91.2%。常规超声共发现32个(13.4%)可疑IDP病灶,诊断敏感性、特异性、阳性预测值、阴性预测值、准确性分别为73.1%、93.9%、59.4%、96.6%、91.6%。结论ABVS冠状面成像可以更好地显示乳腺导管结构,提高对IDP的诊断敏感性,为IDP的诊断及鉴别诊断提供更多信息。  相似文献   

10.
目的对比分析超声弹性成像(UE)与乳腺影像学报告及数据系统(BI-RADS)在乳腺肿块诊断中的价值。方法对483例(541个肿块)乳腺肿块患者(良性358个,恶性183个)分别进行BI-RADS评分及UE检查,以病理诊断为金标准,对比分析UE与BI-RADS评分诊断乳腺肿块良恶性的准确性。结果 UE诊断乳腺肿块的敏感性89.1%、特异性91.9%、准确性90.9%,BI-RADS评分诊断乳腺肿块的敏感性95.6%、特异性70.4%、准确性78.9%。结论 UE对乳腺肿块诊断的准确性高于BI-RADS评分,但临床上应将二者联合应用。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

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