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1.
《中国现代医生》2017,55(32):106-109,封3
目的探讨动态三维子宫输卵管超声造影在输卵管阻塞中的应用。方法选取2015年6月~2016年10月来本院就诊的不孕症患者120例,均行动态三维子宫输卵管超声造影(3D-Hy Co Sy)和X线下输卵管碘海醇注射液造影检查,并与腹腔镜通染液实验(laparoscopy and dye test,CLP)就灵敏度、特异性、准确性进行比较。结果本研究40例患者,共80条输卵管,经3D-Hy Co Sy检测显示输卵管通畅48条,通而不畅15条,阻塞17条;经X线下输卵管碘海醇注射液造影检测显示输卵管通畅47条,通而不畅16条,阻塞17条。两种方法总体符合率为87.50%,有高度一致性(P=0.00,Kappa值=0.779)。以CLP检测结果为对照,3D-Hy Co Sy检测的灵敏度、特异性、准确性分别为90.90%、93.62%、92.50%;而X线下输卵管碘海醇注射液造影检测的灵敏度、特异性、准确性分别为87.88%、89.36%、88.75%。结论在输卵管阻塞患者中实施3D-Hy Co Sy较X线下输卵管碘海醇注射液造影更能全面、客观、安全的显示患者输卵管通畅情况,就其综合优点来分析,有望成为日后输卵管阻塞患者诊治的主要检测方法。  相似文献   

2.
输卵管通畅性的评估,已成为女性不孕症诊疗中不可或缺的重要环节。目前,腹腔镜通染液试验(1aparoscopy and dye test,CLP)被认为是输卵管评估的金标准[1],然而,由于此检查方法有创、成本高和潜在的手术并发症,不易被患者接受。输卵管造影既可以评估输卵管通畅情况又可以确定阻塞部位,具有重要的应用价值[2]。临床上广泛应用的输卵管造影方法包括X线子宫输卵管造影(hysterosalpingography,HSG)和经阴道三维子宫输卵管超声造影(transvaginal three-dimensional hysterosalpingocontrast sonography,TVS 3D-Hy Co Sy)等。  相似文献   

3.
目的:探讨经阴道三维超声输卵管造影(3D-HyCoSy)检查对女性输卵管阻塞不孕患者诊断准确率的影响。方法:选取我院就诊的不孕患者122例(244条输卵管),所有患者均行3D-HyCoSy、X线下输卵管碘海醇注射液造影、腹腔镜通染液实验(CLP)检查,并以CLP检查结果作为参照,统计对比3D-HyCoSy、X线下输卵管碘海醇注射液造影诊断结果。结果:以CLP诊断结果作为参照,3D-HyCoSy诊断出输卵管阻塞93条,X线下输卵管碘海醇注射液造影诊断出输卵管阻塞75条,3D-HyCoSy诊断特异度(92.91%)、敏感度(90.29%)、准确率(91.80%)均较X线下输卵管碘海醇注射液造影(79.43%、72.82%、76.64%)高(P<0.05)。结论:3D-Hy CoS检查可提高女性输卵管阻塞不孕患者诊断特异度、敏感度、准确率,为临床诊治提供重要参考依据。  相似文献   

4.
目的:评价经阴道三维子宫输卵管超声造影对输卵管阻塞病变诊断的临床价值.方法:对103例不孕患者以第2代造影剂SonoVue进行三维超声造影重建术.结果:阴道三维子宫输卵管超声造影显示103例患者200条输卵管中通畅127条,通而不畅42条,阻塞31条;103例患者单侧输卵管不通23例,双侧输卵管不通4例.结论:三维子宫输卵管超声造影是一种可靠、直观、准确评价输卵管通畅性的有效方法.  相似文献   

5.
目的分析及对比二维子宫输卵管超声造影(2D-Hy Co Sy)和子宫输卵管造影(HSG)在评估输卵管通畅性中的应用价值。方法收集本科室2015年8月至2016年8月间接收的患不孕症的50例妇女进行研究,均施行2D-Hy Co Sy检查所有患者的输卵管状况,且与患者的HSG检查结果进行比较分析。结果 2种检查方法的结果对比差异无统计学意义(P0.05)。结论 2D-Hy Co Sy在评估输卵管通畅性中的应用价值与HSG相当,值得推广。  相似文献   

6.
目的探讨三维子宫输卵管超声造影与X线子宫输卵管造影对输卵管通畅性诊断的临床价值。方法收集整理齐齐哈尔医学院附属第二医院不孕患者的临床资料,比较三维子宫输卵管超声造影与X线子宫输卵管造影对输卵管通畅性诊断的结果。结果三维子宫输卵管超声造影检出输卵管不通畅率为96.08%,X线子宫输卵管造影检出输卵管不通畅率为62.75%,三维子宫输卵管超声造影检出输卵管不通率明显高于X线子宫输卵管造影(χ20.05,1=10.67,P=0.001),差异有统计学意义。结论三维子宫输卵管超声造影对输卵管通畅性有较高的诊断精准性,临床应用价值高,可以作为临床首选检查手段。  相似文献   

7.
李娟 《医学理论与实践》2023,(15):2627-2629
目的:探讨与评价多维子宫输卵管超声造影对输卵管性不孕症患者的诊断效果。方法:选择2020年1月—2021年12月在本院进行诊断的输卵管性不孕症患者72例作为观察对象。所有患者均给予多维子宫输卵管超声造影及盆腔水造影检查,同时给予腹腔镜下输卵管通液术检查并判断诊断价值。结果:在72例(共144条输卵管)患者中,腹腔镜下输卵管通液术判断为输卵管通畅56条,输卵管阻塞88条。多维子宫输卵管超声造影判断为输卵管通畅54条,输卵管阻塞90条。盆腔水造影判断为输卵管通畅47条,输卵管阻塞97条。多维子宫输卵管超声造影诊断输卵管阻塞的敏感性、准确性为96.4%、98.6%,均明显高于盆腔水造影的80.4%、91.0%(P<0.05);而多维子宫输卵管超声造影诊断输卵管阻塞的特异性为100.0%,与盆腔水造影的97.7%对比无明显差异(P>0.05)。结论:多维子宫输卵管超声造影在输卵管通畅性评估评价中具有较好的效果,能提高输卵管性不孕症患者的诊断敏感性与准确性,可为不孕症的诊断筛查提供依据。  相似文献   

8.
李斌  严春阳  陈春鸿 《现代实用医学》2014,26(12):1520-1522
目的 探讨经阴道子宫输卵管四维超声造影在女性不孕症中的临床应用价值.方法 回顾性分析接受子宫输卵管四维超声造影的不孕症患者45例患者的临床资料.结果 45例90条输卵管四维子宫输卵管超声造影显示输卵管通畅59条,输卵管不通畅21条,输卵管通而不畅10条;造影显示不全纵膈子宫3例、单角子宫1例.四维子宫输卵管超声造影诊断输卵管阻塞15例共21条输卵管,其中双侧阻塞6例,单侧阻塞9例,均进行了腹腔镜检查与治疗,1例因输卵管壶腹部粘连扭曲,伞端粘连于腹壁超声造影诊断阻塞,腹腔镜为通而不畅,其余20条超声造影结果均与腹腔镜结果一致,两者符合率为95.2%.结论 子宫输卵管四维超声造影可实时动态观察子宫腔情况及输卵管各段通畅性,是不孕症患者诊治前观察和评估输卵管通畅性的重要影像方法.  相似文献   

9.
 目的 对比子宫输卵管三维超声编码造影技术与二维超声造影诊断不孕症患者输卵管通畅性的临床价值。方法 对拟在我院进行腹腔镜通染术的70例不孕患者于术前进行超声造影检查。随机分组后,30例进行二维超声造影,40例进行三维超声编码造影。注入SonoVue后,评估输卵管通畅性。造影后3~7 d进行腹腔镜通染术。结果 二维超声造影灵敏度92.3%、特异度91.2%、阳性预测值88.9%、阴性预测值93.9% 。三维超声编码造影技术灵敏度94.7%、特异度92.9%、阳性预测值92.3%、阴性预测值95.1%;三维超声造影的ROC曲线下面积0.951,二维超声造影的ROC曲线下面积0.849,二者差异具有统计学意义(P=0.021)。结论3D-HyCoSy的最新技术CCI造影对子宫宫腔病变和输卵管通畅性的诊断和鉴别有着明显优势。  相似文献   

10.
目的:探讨声诺维子宫输卵管声学造影(sonovue hysterosalpingo-contrast sonography,sonovue-hycosy)评价输卵管通畅性的价值?方法:对196例原发性或继发性不孕症患者389条输卵管(其中3例患者1侧输卵管切除)进行阴道超声监视下输卵管通水液hycosy检查,判断输卵管的通畅性,对怀疑输卵管阻塞或通而不畅的患者进行声诺维hycosy,判断输卵管的通畅性及阻塞部位,对诊断单侧或双侧输卵管阻塞或通而不畅患者,在进行声诺维hycosy 1周内行腹腔镜检查,将输卵管通畅情况及阻塞部位与腹腔镜通染液试验结果进行对照?结果:196例患者行输卵管通水液hycosy诊断145例患者双侧输卵管通畅,对其余51例(3例1侧输卵管切除)单侧或双侧输卵管阻塞或通而不畅患者进行了声诺维hycosy,诊断54条输卵管通畅,25条通而不畅,20条阻塞;对32例(其中1例1侧输卵管切除)共63条输卵管声诺维hycosy结果与腹腔镜通染液试验结果对照,二者评价输卵管通畅性方面差异无统计学意义?声诺维hycosy诊断阻塞部位的准确率为75%?结论:声诺维子宫输卵管声学造影能实时动态观察输卵管走形及其通畅情况,是一种可靠实用的检查方法,对评价输卵管的通畅性具有重要价值?  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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