Assessment of Effect of Shexiang Baoxin Pill for Labour Angina Pectoris Patients with Computerized Tomography Myocardial Imaging

Assessment of Effect of Shexiang Baoxin Pill for Labour Angina Pectoris Patients with Computerized Tomography Myocardial Imaging@齐华阁@朱永春@许彩茹@郝玉明     

Effect of Xinmaitong Capsule on Total Insche mia Burden in Coronary Heart Disease Patients with Myocardial Ische mia and Analysis of Its The rapeutical Mechanis m

Effect of Xinmaitong Capsule on Total Insche mia Burden in Coronary Heart Disease Patients with Myocardial Ische mia and Analysis of Its The rapeutical Mechanis m@丘瑞香@邝翠仪@刘红健@冯君@贺敬波@蓝军     

Protective Effect of Low-dose Sevoflurane Inhalation and Propofol Anesthesia on the Myocardium after Carotid Endarterectomy: A Randomized Controlled Trial

Background:Myocardial infarction is an important cause of mortality after carotid endarterectomy (CEA).Sevoflurane provides myocardial protection to patients undergoing coronary surgery,but whether it ...     

Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery?

Myocardial revascularization therapy of coronary artery disease is one of the most important medical advances of the past 50 years. Coronary revascularization by either bypass surgery or coronary angioplasty relieves angina and may improve the prognosis in patients with coronary artery disease. Randomized comparisons reveal no difference in survival free from myocardial infarction     

A case of sudden death due to myocardial bridging of the left anterior descending coronary artery

To the editor： Myocardial bridging （MB） is anatomically defined as a segment of a major epicardial coronary artery, which goes through the myocardium. It occurs most frequently in the midportion of the left anterior descending coronary artery. Although traditionally considered as a congenital and benign anatomic variant of the coronary artery, this condition is now associated with angina,     

Quantitative Assessment of Coronary Flow Reserve by the Variables of Time—intensity Curve with Myocardial Contrast Echocardiography

The intrinsic limitations of traditional coro-nary angiography in diagnosis of coronary arterydisease are exposed increasingly.However,the as-sessment of coronary flow reserve ( CFR) is be-coming more and more important,which can rem-edy the disadvantages of traditional coronary an-giography.Myocardial contrast echocardiography( MCE) is a novel technique based on quantifyingmyocardial perfusion.However,the measurementand the resultof variables derived from time- inten-sity curve( TIC) with…     

Genetic epidemiological survey of esophageal cancer in one-tenth of the population of Yangquan city

Genetic epidemiological survey of esophageal cancer in one-tenth of the population of Yangquan city@李卫东 @王秀琴 @张春林 @韩小友 @陈德权 @张卫华 @潘秀芬 @贾运堂 @毛学正 @张睿 @周传农 @吴旻     

Myocardial Viability Favorably Influence On Left Ventricular Remodeling After Acute Myocardial Infarction

Myocardial Viability Favorably Influence On Left Ventricular Remodeling After Acute Myocardial Infarction     

THE EFFECTS OF ELECTRICAL ACUPUNCTURE OF NEIGUAN ON THE PO_2 OF THE BORDER ZONE BETWEEN ISCHEMIC AND NON-ISCHEMIC MYOCARDIUM IN DOGS

Myocardial PO_2 has been determined direct-ly by micro-oxygen electrodes in dogs.Resultsshow that electrical acupuncture of Neiguan re-tarded the reduction of PO_2(partial oxygenpressure)and decreased the amplitude ofreduction in the border zone between ischemicand non-ischemic myocardium after ligation ofthe left descending coronary artery.Thus re-gional isehemia could be reduced while electricalacupuncture of Zusanli showed no such effect.This indicates that the Neiguan point has certainspecificity in the improvement of myocardialoxygen supply.     

Effect of Dauricine on Redistribution of Glycoprotein Ⅳ in Platelet Membrane of Patients with Mitral Stenosis

Effect of Dauricine on Redistribution of Glycoprotein Ⅳ in Platelet Membrane of Patients with Mitral Stenosis@张彦周@刘东旭@李裕舒@冯义柏@毛焕元     

心肌缺血后心肌水肿的磁共振成像研究进展

心肌水肿是缺血性心肌病最常见的病理生理改变之一,磁共振成像(MRI)能评估缺血后心肌水肿的形态和程度。该文综述了MRI对缺血性心肌水肿的分析方法,阐述了其临床应用价值和局限性。其中,T2加权像、23Na MRI可对心肌水肿的形态做出评价,而心肌水肿的弥散加权成像、T2映射、钆对比剂注射后早期成像等技术已日益成熟,可进一步定量评估组织水肿的程度,且能够先于形态学检测到心肌信号的变化。这些分析对缺血性心肌病的病程发展及临床治疗结果的判定很有意义。     

心肌缺血再灌注损伤与心肌细胞凋亡的研究进展

心肌缺血再灌注损伤中存在着不同程度的心肌细胞凋亡的现象。如何减少心肌细胞凋亡已成为心肌保护的研究热点之一,随着研究的不断深入,其在心肌缺血再灌注损伤中应用具有广泛的前景。综述缺血再灌注损伤引起心肌细胞凋亡的证据、可能的相关机制、参与调节的相关基因分子和信号转导、以及初步阐述了目前减少心肌细胞凋亡的方法(缺血预适应和药物预适应)。     

超声二次谐波心肌造影与双核素心肌显像对心肌灌注的评价

[目的] 对比研究超声二次谐波心肌声学造影与双核素心肌显像对心肌灌注的诊断价值.[方法] 对14例冠心病人和6例可疑冠心病者进行冠脉造影(CAG)、经静脉超声二次谐波心肌声学造影(MCE)和双核素单光子发射计算机体层摄影术(SPECT)心肌显像三项检查,共入选冠脉60支和心肌区段180个.MCE和SPECT以左心室9段分法进行心肌灌注记分,以CAG结果为金标准进行MCE和SPECT的对比分析.[结果] 对冠心病的诊断价值MCE和SPECT敏感性均为92.8%,特异性分别为83.3%和66.7%,阳性预测值分别为92.8%和86.7%,阴性预测值分别为83.3%和80.0%,P均＞0.05.两种方法对左前降支、左回旋支病变检出的敏感性、特异性均较右冠状动脉高.根据冠脉狭窄程度将60支冠脉分为4组,各组之间MCE分值差异显著,狭窄程度越大,分值越小,P＜0.05～0.001,同一组中,MCE与SPECT分值差异均无显著性.MCE分值与SPECT分值呈显著正相关(r=0.78,P＜0.01).[结论] 经静脉MCE与双核素SPECT均能有效地检出病变心肌范围和病变冠状动脉,两者对评价心肌灌注有很好的相关性.     

心肌缺血/再灌注损伤与细胞凋亡

在心肌缺血/再灌注损伤中,不仅有细胞坏死,还有细胞凋亡。细胞凋亡与心肌缺血/再灌注损伤呈正比,是心肌缺血/再灌注损伤中的重要病理生理机制。如何减少心肌细胞凋亡已成为心肌保护的研究热点之一。现就缺血/再灌注损伤引起心肌细胞凋亡的证据、可能的相关机制以及参与调节的相关基因分子和信号转导予以综述。     

心肌酶谱检测在急性心肌梗死诊断中的价值

目的:探讨心肌酶谱测定在诊断急性心肌梗死中的应用价值。方法:选取我院2009年1月-2010年1月住院的急性心肌梗死患者40例。测定其肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、同型半胱氨酸(HCY)含量,并与40例正常对照组比较,观察其在诊断急性心肌梗死中的应用价值。结果:AMI组CK、CK-MB、LDH以及HCY检测结果明显高于正常对照组,具有统计学意义(P<0.01)。CK-MB、CK、LDH以及HCY的检出敏感性分别为87.5%、82.5%、75%和57.5%。结论:心肌酶谱测定在诊断急性心肌梗死中具有较好的临床应用价值。     

急性心肌梗死诊断中心肌损伤标志物联合应用的临床价值

目的 比较不同心肌损伤标志物组合诊断急性心肌梗死(AMI)的临床价值.方法 观察四川大学华西医院2005年7月至2006年10月住院的急性胸痛症状患者,根据2007ESC/ACCF/AHA/WHF标准将研究对象分为确诊AMI患者与心梗疑似患者.计算临床常用的心肌损伤标志物[AST,CK,CK-MB,LDH,HBDH,肌钙蛋白I(cTnI), CK-MB mass]各指标诊断AMI的敏感性、特异性、准确性、阳性预测值、阴性预测值、阳性似然比和阴性似然比,采用t检验或方差分析比较不同心肌损伤标志物单项及多项联合指标检测浓度、阳性率、诊断符合率的差异.结果 ①cTnI的敏感性和特异性分别为85%和92.5%,其临床诊断的符合率最高,且差异具有统计学意义(P<0.05);②心肌酶谱和cTnI并联诊断AMI的敏感性和特异性分别为100%和37.29%,其临床诊断符合率较其它并联组高,且差异具有统计学意义(P<0.05);③心肌酶谱和cTnI串联诊断AMI的敏感性和特异性分别为50%和100%,临床诊断符合率较其它串联组高,且其差异均有统计学意义(P<0.05).结论 cTnI具有最高的敏感性和特异性,是诊断和鉴别诊断AMI的较好指标;心肌酶谱的敏感性、特异性较差,应联合cTnI、CK-MB mass进行AMI的诊断和鉴别诊断;纳入cTnI的心肌酶谱组合表现出了最高的敏感性和特异性,即并联试验明显提高了灵敏度,串联试验明显提高了特异性.