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1.
目的探讨惊恐障碍患者的述情障碍及其相关因素.方法采用多伦多述情障碍量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表对伴或不伴广场恐怖的47名惊恐障碍患者和37名健康对照者进行评估.结果(1)伴或不伴广场恐怖的惊恐患者TAS因子Ⅱ分[分别为(3.30±0.70)分和(3.13±0.75)分]高于正常对照组[(2.58±0.67)分](均P<0.05),伴广场恐怖的惊恐患者的TAS总分[(75.4±10.1)分]高于对照组[(66.3±8.9)分](P<0.01),两患者组的因子Ⅰ、Ⅲ和Ⅳ分与对照组之间的差异无显著性(P>0.05),两患者组TAS及四个因子之间的差异亦无显著性(P>0.05);(2)伴与不伴广场恐怖的惊恐患者的HAMA和HAMD得分[HAMA分别为(17.0±6.13)分和(18.6±7.94)分,HAMD分别为(13.0±6.2)分和(15.3±6.96)分]均高于对照组[分别为(0.94±1.22)分和(1.08±0.27)分](P<0.001);(3)伴或不伴广场恐怖的惊恐障碍的TAS因子Ⅱ得分与病程及HAMA和HAMD的相关关系无显著性(P>0.05).结论伴与不伴广场恐怖的惊恐障碍患者均存在述情障碍,以认识和区别情绪和躯体感受的能力欠缺明显,与其病程和焦虑抑郁状态无相关;其描述情感、幻想及外向型思维的能力可能未受损害.  相似文献   

2.
目的 :探讨心身疾病与神经症患者的述情障碍情况。方法 :以多伦多述情障碍量表 (TAS)对 30例心身疾病、31例神经症患者进行测评 ,并与正常人作对照。结果 :心身疾病、神经症患者 TAS总分分别为 (74.10± 7.86 )分、(73.2 2± 9.98)分 ,明显高于对照组 (6 6 .0 6± 6 .38)分。因子分中的 、 、 因子为显著。结论 :述情障碍常见于心身疾病及神经症患者 ,临床医师应予以重视。  相似文献   

3.
抑郁症患者短期治疗前后述情障碍的研究   总被引:2,自引:1,他引:1  
目的 探讨抑郁症患者短期治疗后述情障碍的变化及治疗后述情障碍的影响因素.方法 采用多伦多述情量表(TAS)中文版、Beck抑郁自评量表(BDI),对80例抑郁症患者于治疗前后(新型抗抑郁剂3周以上)进行评定,并与95名健康志愿者(对照组)比较.结果 (1)治疗前抑郁症组TAS与BDI评分均显著高于对照组(P<0.01).重度抑郁组TAS因子I、II及总分均高于轻、中度抑郁组(P<0.05);中度抑郁组仅TAS因子II得分高于轻度抑郁组(P<0.05).(2)治疗后抑郁症患者TAS总分[(52.73±9.41)分]、因子I[(17.88±5.61)分]、因子II[(13.08±3.42)分]、BDI总分[(8.74±7.27)分]较治疗前均降低[分别为 (58.45±10.17)分、(21.56±5.45)分、(16.64±3.35)分、(23.86±9.27)分;P<0.01].治疗后抑郁症组TAS因子I[(17.88±5.61)分]、因子III[(21.78±4.01)分]、总分[(52.73±9.41)分]仍高于对照组[分别为(15.90±4.26)分、(19.09±3.03)分、(48.04±8.79)分;P<0.01].(3)治疗后抑郁总分、服务满意度、治疗信心、对疾病的了解依次进入TAS总分的回归方程.结论 抑郁症存在明显的述情障碍,抑郁总分等是述情障碍的重要影响因素,短期治疗可降低述情障碍的严重程度.述情障碍可能既是一种人格特质,又是对抑郁的一种反应.  相似文献   

4.
抑郁发作患者的述情障碍特征   总被引:2,自引:3,他引:2  
目的了解抑郁发作患者的述情障碍特征;探讨述情障碍与抑郁、焦虑之间的关系。方法符合CCMD3抑郁发作诊断标准的172例患者和对照组172例正常人分别完成多伦多述情障碍20个条目量表(TAS20)中文版、流调中心用抑郁自评量表(CESD)和状态特质焦虑问卷(STAI)。结果抑郁组在TAS20、CESD和STAI的得分上均明显高于正常对照组;抑郁组的述情障碍发生率(42.4%)高于对照组(9.9%);抑郁组中,述情障碍者的CESD得分[(33.72±10.71)分]显著高于非述情障碍者[(24.64±11.27)分],但STAI的得分差异无显著性;TAS20总分与因子1与CESD和STAI均显著相关,且TAS20与特质焦虑的相关(0.318)高于与状态焦虑的相关(0.274)。结论抑郁发作患者表现出明显的述情障碍特征;述情障碍更倾向于作为一种人格特质。  相似文献   

5.
目的 :探讨十二指肠溃疡患者述情障碍、个性特征及相互之间的关系 .方法 :采用多伦多述情障碍量表 (TAS)和艾森克成人个性问卷 (EPQ)对 6 5例十二指肠溃疡患者进行测评 ,并与正常健康者作对照 .结果 :十二指肠溃疡组TAS总分 (72 0 6± 11 0 5 )分 ,明显高于对照组 (6 6 39± 8 93)分 (P <0 0 1) ,各因子分比较也有显著性差异 (P <0 0 1) .溃疡组EPQ的N分和对照组相比差异有高度显著性 (P <0 0 1) .多元相关分析发现 ,十二指肠溃疡组TAS的Ⅲ、Ⅳ因子分和个性维度E呈负相关 ,TAS的Ⅰ、Ⅱ因子分和个性维度N呈正相关 .结论 :十二指肠溃疡患者存在述情障碍 ,且与个性特征等心理社会因素密切相关 .  相似文献   

6.
脑卒中患者睡眠障碍及影响因素研究   总被引:12,自引:0,他引:12  
目的观察脑卒中患者睡眠障碍发生情况及可能的影响因素。方法对入选病例分别采用匹兹堡睡眠质量指数(PSQI)、神经功能缺损程度评分(NDS)、改良Barthel指数(MBI)、汉密尔顿抑郁量表(HAMD)及汉密尔顿焦虑量表(HAMA)进行测评。结果在154例脑卒中患者中,睡眠障碍患者(PSQI总分>7分者)92例(59.7%)。睡眠障碍患者与非睡眠障碍患者在平均年龄[(68.6±11.7)岁vs(60.2±11.3)岁,P<0.01]、女性百分比[68.6%vs31.4%,P<0.01]、HAMD[(13.6±8.2)分vs(5.3±2.4)分,P<0.01]、HAMA[(8.3±1.2)分vs(3.5±0.8)分,P<0.05]、MBI[(58.7±14.3)分vs(70.2±15.6)分,P<0.01]及NDS[(19.1±6.3)分vs(12.6±5.4)分,P<0.01]评分方面比较,均差异有显著性(P<0.05或<0.01)。多元逐步回归分析显示,睡眠障碍与患者的日常生活能力、抑郁状态、神经功能缺损程度、脑卒中的部位及病变范围大小密切相关。结论脑卒中患者睡眠障碍较为常见,改善睡眠有助于患者的神经功能缺损康复和生活质量提高。  相似文献   

7.
目的探讨偏头痛患者述情障碍及综合护理干预。方法采用多伦多述情障碍量表(TAS)对58例偏头痛患者进行测评,并针对性的实施综合护理干预;结果偏头痛患者多伦多述情障碍量表(TAS)总分及各因子分均高于常模水平(P<0.05)。结论偏头痛患者存在述情障碍,由此进行针对性综合护理干预有利于缓解患者的负性情绪,促进病情缓解,减少复发。  相似文献   

8.
目的:探讨哮喘患者的述情障碍及其与个性的相关性.方法:采用多伦多述情障碍量表(TAS)、艾森克人格问卷简式量表中国版(EPQ-RSC)对52例哮喘患者进行测查.结果:与常模比较,哮喘患者存有明显的述情障碍.哮喘患者的TAS总分、Ⅰ、Ⅱ、Ⅲ及Ⅳ因子与EPQ-RSC的个性维度E、Ⅲ因子与个性维度N呈显著负相关;TAS总分、Ⅰ、Ⅱ因子与个性维度N、Ⅱ和Ⅳ因子与个性维度P均呈显著正相关.结论:哮喘患者普遍存在述情障碍,且与个性特征有密切关系.  相似文献   

9.
目的:探讨哮喘患者的述情障碍及其与个性的相关性。方法:采用多伦多述情障碍量表(TAS)、艾森克人格问卷简式量表中国版(EPQ-RSC)对52例哮喘患者进行测查。结果:与常模比较,哮喘患者存有明显的述情障碍。哮喘患者的TAS总分、Ⅰ、Ⅱ、Ⅲ及Ⅳ因子与EPQ-RSC的个性维度E、Ⅲ因子与个性维度N呈显著负相关;TAS总分、Ⅰ、Ⅱ因子与个性维度N、Ⅱ和Ⅳ因子与个性维度P均呈显著正相关。结论:哮喘患者普遍存在述情障碍,且与个性特征有密切关系。  相似文献   

10.
父母养育方式对躯体化障碍患者述情障碍的影响   总被引:1,自引:0,他引:1  
目的:探讨父母养育方式对躯体化障碍患者述情障碍的影响。方法:应用多伦多述情障碍量表(TAS)、父母养育方式评价量表(EMBU)对85例躯体化障碍患者和74例健康对照组进行测评。结果:研究组TAS总分和各因子分均高于对照组;父亲养育方式中因子Ⅱ、因子Ⅴ等2项高于对照组;母亲养育方式中因子Ⅰ、因子Ⅱ、因子Ⅲ、因子Ⅳ等4项高于对照组;tAS的因子Ⅰ与EMBU父亲因子Ⅱ呈正相关,与母亲因子Ⅰ呈负相关;TAS的因子Ⅱ、因子Ⅲ与母亲因子Ⅱ、因子Ⅲ、因子Ⅳ呈正相关;TAS的因子Ⅳ与父亲因子Ⅲ呈正相关。结论:躯体化障碍患者存在较严重的述情障碍,其父母养育方式对述情障碍有明显影响。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

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