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1.
目的 观察输尿管镜气压弹道碎石术治疗上尿路结石急性梗阻性肾功能衰竭的疗效.方法 2003年4月至2008年12月对该院11例17侧上尿路结石急性梗阻性肾功能衰竭患者急诊行输尿管镜检查、气压弹道碎石术,术后留置双J管引流.结果 10例16侧一次性击碎结石,留置双J管,1例患者因其孤立肾的输尿管结石较大、肉芽组织包裹改行开放手术取石.术后3~14 d,7例患者血肌酐(Cr)由456~1 369 μmol/L降至 89~127 μmol/L,2例患者于术后1个月Cr水平恢复正常,另2例患者术后3个月处于氮质血症(Cr 189~317 μmol/L).所有患者术后1个月复查腹部平片(KUB)无结石残留.结论 输尿管镜气压弹道碎石术治疗上尿路结石致急性梗阻性肾功能衰竭的疗效确切,创伤小,同时处理双侧输尿管结石,可作为急性梗阻性肾功能衰竭的首选治疗方法.  相似文献   

2.
程波 《中外医疗》2013,(18):95-96
目的探讨采取措施对输尿管镜气压弹道碎石术治疗输尿管结石、梗阻性急性肾功能衰竭的疗效。方法从医院收治的输尿管结石梗阻性急性肾功能衰竭患者中选取10例,其中男6例,女4例,他们的年龄在25~80岁之间。患者的血清肌酐(Cr)与血尿氮素(BUN)的含量升高。这些患者中,输尿管中段结石的有7例,输尿管下段结石的有3例。单侧输尿管结石并对侧的肾功能衰竭的有6例,两侧输尿管结石的有4例。利用输尿管镜气压弹道碎石术的方法对患者进行治疗,并对治疗疗效进行有效性观察与研究。结果经过手术治疗与护理,10例输尿管结石梗阻性急性肾功能衰竭患者的病情均得到有效缓解。10例患者均为1次性将输尿管腔打通,放置双J管。术后没有患者出现输尿管断裂、撕脱、穿孔等一些较为严重的临床并发症,患者的血清肌酐与血尿氮素含量恢复正常,在手术结束1个月后患者体内的双J管拔除。结论利用输尿管镜气压弹道碎石术对输尿管结石梗阻性急性肾功能衰竭患者进行治疗,不仅减轻了患者所承受的生理与心理痛苦,而且临床疗效好,具有极强的临床研究与应用价值。  相似文献   

3.
目的探讨输尿管镜气压弹道碎石治疗急性输尿管结石梗阻性无尿的效果。方法对12例急性输尿管结石梗阻性无尿患者进行输尿管镜气压弹道碎石治疗。结果一次行双输尿管碎石者8例。一侧插双J管碎石者4例,5~7天后再行插双J管侧碎石。治疗后11例肾功能恢复正常(91.7%),1例(8.3%)于术后3个月血肌酐仍达213umol/1。结论输尿管镜气压弹道碎石是治疗急性输尿管结石梗阻性无尿的有效方法,可作为首选。  相似文献   

4.
目的 探讨经输尿管镜碎石取石术在急性上尿路结石梗阻肾功能衰竭中的疗效.方法 对48例因上尿路结石梗阻引起急性肾功能衰竭的患者急诊行输尿管镜气压弹道碎石术治疗,术后均留置双J管.结果 除2例因术中进镜受阻改行输尿管切开取石术外,余46例均可在输尿管镜下行碎石术,5例因术中结石移位至肾盂肾盏造成结石残留者于术后2周行体外冲击波碎石术治疗.所有患者的肾功能均得到明显改善.结论 采用输尿管镜气压弹道碎石术急诊处理上尿路结石梗阻引起的急性肾功能衰竭患者,具有微创、安全、效果显著的优点,可作为首选的治疗方法.  相似文献   

5.
①目的探讨输尿管镜下气压弹道治疗上尿路结石梗阻并发急性肾功能衰竭有效性和安全性。②方法应用输尿管镜直视气压弹道碎石术治疗输尿管结石梗阻并急性肾功能衰竭10例。③结果术后7天患者血清BUN,Cr均恢复正常或接近正常,尿量恢复,术后3天结石排净率90%(9/10)。④结论输尿管镜下气压弹道治疗上尿路结石性梗阻并发急性肾功能衰竭,具有安全、疗效可靠、损伤小等优点,能同时处理双侧输尿管病变,可作为首选治疗方法。  相似文献   

6.
目的 探讨输尿管镜下弹道碎石术治疗输尿管结石梗阻导致的急性肾功能衰竭的临床疗效.方法 采用经输尿管镜气压弹道碎石术治疗输尿管结石梗阻导致的急性肾功能衰竭20例.结果 20例均一次性解除梗阻,一次性碎石成功17例,改开放手术1例,术后配合体外碎石术2例.术中均留置双"J"管,梗阻均解除.术后19例肾功能恢复正常,1例轻度异常.结论 输尿管镜下弹道碎石术治疗输尿管结石梗阻导致的急性肾功能衰竭安全、疗效好、恢复快.  相似文献   

7.
目的 探讨输尿管镜治疗急性上尿路梗阻性肾功能衰竭的作用及疗效.方法 对32例上尿路结石梗阻导致急性肾功能衰竭患者行输尿管镜下探查、气压弹道碎石、置双J管治疗.结果 32例均成功解除梗阻,31例术后肾功能复查正常.结论 对于上尿路结石梗阻引发急性肾功能衰竭,输尿管镜下气压弹道碎石术具有效果显著、实用安全的优点,值得推广应用.  相似文献   

8.
聂士富  王传圣  程华根  汪勇 《吉林医学》2011,(35):7535-7536
目的:探讨输尿管镜下气压弹道碎石治疗输尿管结石梗阻所致急性肾功能衰竭的安全性和有效性。方法:应用输尿管镜气压弹道碎石术治疗双侧输尿管结石梗阻所致肾功能衰竭17例,孤立肾输尿管结石梗阻所致肾功能衰竭4例。结果:4例孤立肾患者手术均一期成功,3例结石1周排除,1例配合体外冲击波碎石(ESWL)治疗,3周后复查无残留结石。17例双侧输尿管结石患者,15例手术一期解除梗阻,2例一侧成功置管,另一侧行肾脏造瘘术,4例配合ESWL治疗,3周后复查15例结石排尽。16例患者BUN和SCr2周内恢复正常,5例经长期治疗,BUN:11.8~13.4 mmol/L,SCr:180~260μmol/L。均未发生术中术后并发症21例。结论:输尿管镜下气压弹道碎石治疗上尿路结石致梗阻性肾功能衰竭安全、有效。  相似文献   

9.
目的 探讨急诊输尿管镜下气压弹道碎石术治疗输尿管结石致急性肾功能衰竭的效果.方法 对24例诊断明确的患者采用急诊行输尿管镜下气压弹道碎石术治疗,其中孤立肾5例,一侧输尿管结石对侧肾萎缩12例,双侧输尿管结石7例.结果 24例患者共31侧结石均碎石成功,梗阻解除,21例患者血肌酐及尿素氮恢复致正常,3例合并有慢性肾功能不全的患者血肌酐恢复到200umol/L以下,无严重并发症.结论 输尿管镜下气压弹道碎石术治疗输尿管结石致肾功能衰竭具有成功率高、损伤小、恢复快、并发症少、可同时处理双侧结石等优点,在具备条件的医疗单位应作为首先的治疗方法.  相似文献   

10.
目的探讨输尿管镜及气压弹道碎石术治疗急性梗阻性肾功能衰竭的效果。方法应用输尿管镜直视取石或气压弹道碎石术治疗输尿管结石梗阻合并急性肾功能衰竭89例。结果结石清除率93%(83/89),血尿素氮(BUN)、肌酐(Cr)恢复正常或接近正常。结论输尿管镜及气压弹道碎石术治疗急性梗阻性肾功能衰竭,具有安全、疗效可靠、创伤小、并发症少的优点,值得推广。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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