双源CT对下肢动脉阻塞性疾病的诊断及其临床价值

目的:探讨双源CT对下肢动脉阻塞性疾病的诊断价值. 方法:对38例疑为下肢动脉阻塞性疾病患者行双源下肢动脉血管成像(CTA)扫描,并对13例患者1周内同时行数字减影血管造影(DSA).将下肢血管分成12段,每段血管的狭窄程度被分为:正常、轻度狭窄、中度狭窄、重度狭窄、闭塞5个级别,并将CTA与DSA结果进行比较. 结果:CTA与DSA在显示狭窄程度方面一致性非常好(Kappa值为0.896).以DSA为参照标准,在血管节段基础上,CTA诊断下肢动脉闭塞的敏感度、特异性、准确性分别为100.0%、99.2%、99.3 %,诊断管腔中度以上狭窄的敏感度、特异性、准确性分别为100.0 %、96.7 %、97.9 %. 结论:双源CTA在评估下肢动脉阻塞性疾病方面与DSA有很好的一致性,是下肢动脉阻塞性疾病的可靠诊断方法.     

多层螺旋CT在下肢动脉闭塞性疾病中的诊断价值

目的 探讨多层螺旋CT血管成像术在下肢动脉闭塞性疾病中的诊断价值.方法 对63例临床可疑的外周动脉闭塞性疾病患者行下肢动脉多层螺旋CT血管造影(CTA),扫描范围从肾动脉水平达足底.薄层重建横断面图像传入HP xw8000工作站,进行血管三维重建.结合常规血管造影(DSA)评价CTA诊断的准确性.结果 在1 323个动脉节段中,1 305个节段在CTA与DSA均可以显示,DSA显示狭窄和闭塞的节段共390个,其中轻度狭窄48个,中度狭窄36个,重度狭窄66个,闭塞240个;CTA显示狭窄和闭塞的节段共393个,其中轻度狭窄51个,中度狭窄30个,重度狭窄72个,闭塞240个.最大密度投影(MIP)显示CTA对中度及中度以上狭窄诊断的敏感性、特异性及准确性分别为99.1%、99.7%和99.5%.结论 多层螺旋CT在评估下肢动脉闭塞性疾病方面与常规血管造影结果无明显差别,是下肢动脉闭塞性疾病理想的影像学检查手段.     

高分辨率磁共振成像与CT血管造影评价大脑中动脉狭窄和斑块性质的效果对比

目的 比较高分辨率磁共振成像(HR-MRI)与CT血管造影(CTA)对大脑中动脉狭窄和斑块性质的评价效果.方法 选取20例经数字减影血管造影(DSA)确诊大脑中动脉狭窄的患者,均行HR-MRI和CTA检查,比较两种方法对大脑中动脉狭窄的诊断效能及对斑块性质的评估效果,并评价两种方法与DSA评价管腔狭窄程度的一致性.结果 DSA显示共24支大脑中动脉发生血管狭窄.CTA与HR-MRI对大脑中动脉狭窄的检出率、诊断大脑中动脉狭窄的灵敏度、特异度及准确性比较,差异均无统计学意义(P>0.05).在评价血管狭窄程度方面,HR-MRI与DSA呈高度一致性(κ=0.770,P=0.016),CTA与DSA呈中度一致性(κ=0.528,P=0.031).HR-MRI对大脑中动脉斑块的总检出率及易损斑块、稳定斑块的检出率均高于CTA(P<0.05).结论 HR-MRI在评估大脑中动脉狭窄和斑块性质方面比CTA更具优势.     

HR-MRI评估大脑中动脉粥样硬化性狭窄程度的价值探讨

目的探讨高分辨率磁共振成像(High-resolution magnetic resonance imaging,HR-MRI)诊断大脑中动脉粥样硬化性狭窄程度的价值。方法回顾性分析2009年1月至2014年2月我院门诊部收治的50例经手术病理证实的大脑中动脉粥样硬化性狭窄临床资料,患者均行HR-MRI及数据减影血管造影(Digital subtraction angiography,DSA)检查,以DSA为诊断金标准评估HR-MRI在大脑中动脉粥样硬化性狭窄程度中的诊断价值。结果 50例患者共100段大脑中动脉M1段,HR-MRI及DSA均显示未见狭窄血管、轻度狭窄血管、中度狭窄血管、重度狭窄血管及闭塞血管分别为48段、8段、18段、15段、6段;HR-MRI对大脑中动脉硬化狭窄程度与DSA诊断一致的有95段,诊断符合率为95.00%,HR-MRI诊断偏高2段,百分比为2.00%,诊断偏低3段,百分比为3.00%。结论 HR-MRI对大脑中动脉粥样硬化性狭窄程度诊断与DSA诊断方法具有较高符合率,HR-MRI在颅内血管病变狭窄程度的诊断具有一定诊断价值,值得临床推广应用。     

SCTA在急性脑梗死患者颈动脉系统检查中的应用研究

目的探讨螺旋CT血管造影(SCTA)应用于急性脑梗死患者颈动脉系统检查中的临床价值。方法选取从2015年10月至2016年10月在就诊于我院的急性脑梗死患者50例进行分析。在治疗前,对所有患者进行数字减影血管造影(DSA)、颈部血管超声(CVUS)以及SCTA,并且以DSA结果作为参照标准,对比经CVUS和SCTA检查的颈动脉狭窄检出率、颈动脉狭窄率、颈动脉狭窄程度以及颈动脉斑块检出率,对SCTA检查做出评价。结果 (1)经SCTA和CVUS检查检出颈动脉狭窄的检出率分别为52%和50%,差异不具有统计学意义(P0.05);(2)SCTA和C V U S检出的颈动脉狭窄率分别为(32.98±10.92)%和(31.07±10.33)%,两者差异并无统计学意义(P0.05);(3)经SCTA和CVUS检查检出颈动脉狭窄情况的准确率分别为74%和46%,差异具有显著的统计学意义(P0.05);(4)经SCTA和CVUS检查检出颈动脉斑块检出率分别为93.22%和73.73%,差异具有显著的统计学意义(P0.05)。结论相比于同样是无创的CVUS,螺旋CT血管造影(SCTA)在急性脑梗死患者颈动脉系统检查中不仅能更好地判断颈动脉狭窄情况,还能更好地检出动脉斑块。     

大脑中动脉狭窄的TCD、MRA、DSA测对比研究

目的 以数字减影脑血管造影(DSA)为参照,比较经颅多普勒彩色超声(TCD)、核磁共振血管成像(MRA)、DSA诊断大脑中动脉狭窄的准确性,评价其临床价值.方法 对24例经DSA确诊的单双侧43处大脑中动脉狭窄的患者,回顾分析TCD、MRA的检查结果.比较其对大脑中动脉(MCA) M1段、M2段狭窄诊断的准确率.结果 TCD、MRA、DSA诊断MCAM1段、M2段狭窄的准确率分别为82.4％、94.1％、100.0％及22.2％、77.8％、100.0％.三者对MCA M1段狭窄的诊断差异无统计学意义(P＞0.05),而对M2段狭窄的诊断,TCD与MRA、DSA比较差异有统计学意义(P＜0.05),而MRA与DSA差异无统计学意义(P＞0.05).结论 MRA、DSA均能准确显示MCA狭窄,TCD有局限性,三者均能为临床提供参考价值.     

磁共振血管成像判断颅内动脉狭窄程度的应用价值

目的：探讨磁共振血管成像（MRA）对颅内动脉狭窄程度的应用价值。方法：收集MRA显示颅内动脉血管不同程度狭窄162支,采用目测法根据血管形态、血流信号、远段血管显示状况进行分析,主要观察颈内动脉海绵窦段,大脑中动脉M1/M2段,大脑前动脉A1/A2段,大脑后动脉P1/P2段。结果：MRA诊断颅内血管轻度狭窄92支,占56.8%,中度狭窄45支,占27.8%,重度狭窄或闭塞25支,占15.4%。结论：MRA血管成像对颅内血管狭窄诊断敏感,但常常因为血流的特性造成信号缺失而造成假象。运用标准尺测量血管管径误差率较高,综合分析血管管腔形态、走行、局部和远段血流信号改变来评估血管狭窄程度较为可靠。     

128排螺旋CT在脑梗死患者脑血管狭窄临床诊断中的价值

目的观察128排螺旋CT血管造影(CTA)在脑梗死患者脑血管狭窄临床诊断中的价值。方法选取2018年10月至2019年10月本院收治的120例脑梗死患者作为研究对象,均经CTA和数字减影血管造影术(DSA)检查,以DSA为"金标准",比较脑血管狭窄位置、数量及直径,并统计CTA诊断准确率和误诊率。结果 120例患者共检测可疑脑血管485支,CTA检查脑血管狭窄位置及数量总符合率为96.72%;CTA诊断脑血管狭窄准确率为95.26%,其中诊断轻度狭窄准确率为82.61%,中度狭窄准确率为95.71%,重度狭窄准确率为100.0%,误诊率为4.74%(23/485);DSA和CTA检测大脑前动脉、大脑中动脉、大脑后动脉、椎动脉、颈内动脉及基底动脉狭窄直径比较差异无统计学意义(P0.05)。结论 CTA可准确判断脑梗死患者脑血管狭窄位置、数量、直径及狭窄程度,且费用较低,安全性较高,值得临床进一步推广。     

颈部血管超声与DSA在颈部动脉狭窄诊断中的比较

目的 评价血管超声检查在颈部动脉狭窄检测中的敏感度、特异度和准确度.方法 对68例患者408条颅外动脉血管同时进行血管超声及数字减影血管造影(DSA)检查,以DSA为金标准,用四格表法分析血管超声检查对轻度、中度、重度狭窄及闭塞的颈部动脉血管病变检出的敏感度、特异度及准确率,超声与DSA诊断的一致性采用Kappa检验.结果 对轻度血管狭窄检出的敏感度、特异度及准确率分别为45.0%、96.6%、94.4%;中度狭窄者分别为35.0%、99.5%、96.3%;重度狭窄者分别为47.6%、99.5%、96.9%;闭塞者分别为64.7%、99.5%、99.0%.与DSA比较,对轻度、中度、重度狭窄及闭塞的Kappa值分别为0.409、0.467、0.591、0.723.超声对于狭窄诊断的总体敏感度、特异度、准确率分别为66.7%、99.4%、83.1%,Kappa值为0.749.结论 血管超声检查技术对于轻度、中度、重度血管狭窄及闭塞的检出准确率、特异度均较高,但是灵敏度较低,轻、中、重度狭窄与金标准的吻合度一般,对闭塞的吻合度较高,提示超声对中度狭窄以上病变有较好的诊断价值.     

多普勒超声联合CT血管造影在糖尿病下肢血管病变诊断中的价值研究

目的探讨多普勒超声联合CT血管造影(CTA)在糖尿病下肢血管病变(LEAD)诊断中的价值。方法回顾性分析我院接诊的103例LEAD患者的临床资料,以X线数字减影血管造影(DSA)检查结果为诊断依据,均行多普勒超声和CTA检查,分析多普勒超声联合CTA诊断LEAD的准确性。结果 103例LEAD患者共检测1648段血管,DSA检出狭窄血管610段(37.01%),CTA检出狭窄血管600段(36.41%),多普勒超声检出狭窄血管535段(32.46%);DSA与CTA狭窄血管检出率比较,差异无统计学意义(χ^2=0.13,P>0.05);DSA狭窄血管检出率显著高于多普勒超声(χ^2=7.53,P<0.05);下肢动脉各节段多普勒超声联合CTA诊断与DSA比较,符合的1566段,准确率为95.02%,高估狭窄程度31段,低估狭窄程度51段,kappa值=0.901。结论多普勒超声联合CTA有助于提高诊断LEAD的准确性,联合成像与DSA的一致性较好。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.