首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 62 毫秒
1.
目的研究比较不同病理类型伴钙化乳腺癌的X线征象,提高对乳腺癌的诊断水平。方法搜集术前行数字化钼靶X线检查术后经病理证实的伴钙化乳腺癌患者82例,将不同病理类型乳腺癌的X线征象进行对照。结果伴钙化乳腺癌中,单纯钙化多见于导管原位癌和浸润性导管癌,钙化伴肿块在各种病理类型乳腺癌中均可见,以浸润性导管癌为多,钙化伴结构紊乱者多见于浸润性导管癌。结论乳腺钼靶X线检查可作出乳腺癌组织类型的初步诊断。  相似文献   

2.
目的 研究比较不同病理类型伴钙化乳腺癌的X线征象,提高对乳腺癌的诊断水平.方法 搜集术前行数字化钼靶X线检查术后经病理证实的伴钙化乳腺癌患者82例,将不同病理类型乳腺癌的X线征象进行对照.结果 伴钙化乳腺癌中,单纯钙化多见于导管原位癌和浸润性导管癌,钙化伴肿块在各种病理类型乳腺癌中均可见,以浸润性导管癌为多,钙化伴结构紊乱者多见于浸润性导管癌.结论 乳腺钼靶X线检查可作出乳腺癌组织类型的初步诊断.  相似文献   

3.
目的研究乳腺癌X线征象,提高对乳腺病变尤其是乳腺癌的诊断水平。方法搜集术前行钼靶X线检查术后经病理证实的伴钙化的乳腺癌患者82例及伴钙化的乳腺良性病变患者12例进行回顾性分析,将伴钙化的不同病理类型乳腺癌的X线征象进行对照;以伴钙化的乳腺癌为研究对象,设对照组,对其钙化的大小、形态、密度是否一致进行分析。结果不同病理类型乳腺癌其钼靶X线表现不一,含有钙化的病变多见于导管原位癌和浸润性导管癌,钙化伴肿块在各种病理类型乳腺癌中均可见,以浸润性导管癌为多,钙化伴结构紊乱者多见于浸润性导管癌;乳腺癌的钙化多为细钙化,且形态、密度不一致。掌握这一特征,可发现隐匿性及早期乳腺癌。结论钼靶乳腺摄影是诊断和鉴别诊断乳腺癌的重要方法。  相似文献   

4.
目的:通过分析乳腺浸润性导管癌的钼靶X线表现,以进一步提高乳腺浸润性导管癌的钼靶X线影像诊断水平.方法:回顾性分析经手术病理证实的76例女性乳腺浸润性导管癌的钼靶X线影像学资料和数据.结果:乳腺浸润性导管癌钼靶X线表现多样,最常出现的征象是肿块71例(93.4%),浸润性导管癌中有恶性钙化46例(60.5%),肿块同时伴钙化者42例(55.3%),表现为结构扭曲者浸润性导管癌的3.9%.结论:乳腺浸润性导管癌常见的X线表现为肿块、钙化、和结构扭曲.  相似文献   

5.
目的:分析钼靶片中乳腺癌微钙化与人类上皮生长因子受体-2(C-erbB-2)表达及临床病理关系,评价微钙化征象预测C-erbB-2表达的可行性。方法:乳腺癌病例55例,钼靶X线片均由两位有经验的影像诊断医师阅片,明确钙化并根据钙化及相关表现分组。免疫组化采用SP法,根据癌细胞核内染色判断C-erbB-2表达情况。各钙化分组分别与C-erbB-2表达情况进行比较分析。结果:乳腺癌微钙化多见于DCIS及浸润性导管癌,占57.5%(23/42),是钼靶片中无肿块表现乳腺癌的主要X线征象。乳腺癌钼靶片中微钙化的有无、微钙化数目、钙化类型与癌细胞C-erbB-2表达有相关性(P〈0.05)。结论:微钙化在钼靶片乳腺癌诊断中,特别是在早期癌以及无肿块表现的乳腺癌诊断中具有重要意义,在一定程度上反映了C-erbB-2的表达状态。  相似文献   

6.
目的分析全数字化乳腺钼靶X线摄影在乳腺癌诊断中的价值。方法回顾性分析95例乳腺癌患者的临床资料。结果 95例均经数字化乳腺钼靶X线摄影诊断为乳腺癌,并经手术病理证实。其中直接征象仅有肿块者54例,肿块伴钙化33例,腺体结构紊乱9例,局部致密影6例,仅有钙化7例。间接征象异常血管征33例,腋窝淋巴结肿大21例,皮肤增厚29例,乳头凹陷21例,主乳导管扩张4例。浸润性导管癌73例,浸润性小叶一导管癌6例,导管原位癌10例,混合性癌3例,粘液癌2例,Pagets病1例。结论全数字化乳腺钼靶X线摄影诊断乳腺癌的诊断及鉴别诊断有重要意义。  相似文献   

7.
目的探讨数字化钼靶检查诊断乳腺浸润性导管癌的诊断价值.方法收集2009年10月至2011年10月经手术病理证实的62例乳腺浸润性导管癌,回顾分析乳腺浸润性导管癌钼靶X线征象,参照BI-RADS标准进行读片分析.结果乳腺浸润性导管癌分布于外上象限居多,占50%,内下象限最少,占6.45%;91.49%的肿块钼靶X线所见均较触诊体积小;肿块、病灶边缘模糊、中间性或高度可疑恶性钙化、分叶征和毛刺征分别占75.81%、95.16%、87.10%、46.77%、43.55%.结论肿块、病灶边缘模糊、中间性或高度可疑恶性钙化、分叶征和毛刺征是诊断乳腺浸润性导管癌的可靠征象,其他间接征象可为诊断提供帮助.  相似文献   

8.
目的:分析乳腺浸润性导管癌的钼靶X线征象,研究各类征象的X线诊断价值,提高乳腺浸润性导管癌的诊断水平。方法:乳腺手术后病理证实的48例浸润性导管癌,回顾性研究术前乳腺钼靶X线征象。结果:48例乳腺浸润性导管癌中,肿块41例,伴有毛刺32例,恶性钙化灶29例,局部结构扭曲11例,局部血运增加13例,局部皮肤增厚12例,乳头凹陷5例,腋下淋巴结肿大13例。  相似文献   

9.
目的 探讨浸润性导管癌(IDC)钼靶X线表现和雌激素受体(ER)、孕激素受体(PR)及人类上皮生长因子2之间(c -erbB- 2)的关系,评价导管癌钼靶X线表现,术前预测浸润性导管癌的ER、PR、c- erbB- 2的表达的可行性。方法 35例乳腺钼靶和临床病理证实的浸润性导管癌,术后大体标本经免疫组织化学染色判断这些免疫因子的表达情况。把浸润性导管癌钼靶X线表现中的恶性钙化、肿块边缘的毛刺与ER、PR及c -erB- 2表达情况进行对比。结果 35例导管癌中, 肿块伴毛刺者25例,有钙化者14例;ER阳性者21例,毛刺组ER阳性率与无毛刺组相比有显著性差异(P<0 .05)。无钙化组ER阳性率较有钙化组高,但无统计学意义;PR表达阳性者23例,毛刺组PR阳性率较无毛刺组高,钙化组PR阳性率较无钙化组略高,无统计学意义; c- erbB- 2表达阳性者25例,无毛刺组c -erbB -2阳性率较毛刺组高,无统计学意义。钙化组c -erbB -2阳性率与无钙化组相比有显著性差异(P<0. 05 )。结论 IDC中毛刺性肿块与ER表达、钙化性肿块和c- erB- 2、PR表达之间有相关性,钼靶X线征像可以粗略反映ER、PR及c- erB -2表达情况。  相似文献   

10.
目的探讨乳腺癌钼靶X线表现与癌细胞雌激素受体(ER)、孕激素受体(PR)及人体抑癌基因(P53)生物学相关性,旨在为乳腺癌的早期诊断及预测预后提供依据。方法回顾性分析经手术病理证实的152例乳腺浸润性导管癌患者为研究对象。患者均于术前行钼靶X线检查,重点观察病变肿块、钙化、结构紊乱、局部密度增高等。以病理组织学结果做对照。术后标本测定ER、PR、P53的表达情况,分析其与钼靶X线表现间的关系。结果 152例浸润性导管癌中,表现为肿块伴毛刺或形态不规则与ER、PR表达关联(χ2=8.108,P〈0.05;χ2=5.571,P〈0.05);有钙化与ER、PR表达有统计学差异(χ2=4.851,P〈0.05;χ2=4.579,P〈0.05);乳腺结构紊乱或局部密度增高与ER、PR表达差异有统计学意义(χ2=6.521,P〈0.05;χ2=5.602,P〈0.05);乳腺结构紊乱或局部密度增高与P53表达有统计学差异(χ2=7.883,P〈0.05)。结论乳腺癌的一些重要钼靶X线征象与ER、PR、P53之间存在一定相关性,在一定程度上反映了乳腺癌细胞的生物学行为和预后,为临床早期诊断和治疗提供更多客观依据。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号