惠州市不同人群丙型肝炎病毒感染状况分析

目的了解不同人群的丙型肝炎感染状况,为丙型肝炎防治工作提供科学依据。方法采用分层抽样方法抽取了惠州市19 219例对象,采用酶联免疫吸附法(ELISA)检测丙型肝炎病毒(HCV)抗体。结果本次调查人群的HCV平均感染率为3.55%,略高于全国3.22%的平均水平;不同群体中丙型肝炎阳性率差异显著,吸毒群体阳性率最高,为54.8%;不同年龄组的抗-HCV总阳性率差异有统计学意义,吸毒人群不同年龄组的抗-HCV阳性率差异有统计学意义(χ2=77.431,P<0.01);男性抗-HCV阳性率(4.94%)明显高于女性(0.88%)。结论静脉吸毒是HCV主要传播途径,通过对高危行为人群开展健康干预、抗HCV筛查和临床治疗,有效防止丙型肝炎在人群中扩散。     

江苏省2005~2008年吸毒人群艾滋病病毒哨点监测结果分析

目的:通过对2005～2008年江苏省吸毒人群艾滋病病毒(HIV)哨点监测结果的分析,了解该人群艾滋病感染状况及高危行为状况变化趋势,评价近年对吸毒人群的干预效果。方法:采用SPSS11.5统计软件对2005～2008年江苏省7个吸毒人群艾滋病哨点监测数据进行统计分析。结果:吸毒人群中艾滋病病毒抗体(HIV抗体)阳性率为0.7%,丙肝(HCV)阳性率为34.04%。注射吸毒率逐年呈下降趋势且有统计学差异(χ2=156.66,P<0.01);注射吸毒且共用针具者与注射吸毒但不共用针具者艾滋病感染状况有统计学差别(χ2=18.173,P<0.01);发生商业性行为时从不使用安全套的比例有逐年下降趋势(χ2=11.67,P<0.01)。此外,注射吸毒者HCV感染率与非注射吸毒者HCV感染率有统计学差异(χ2=708.945,P<0.01)。结论:在吸毒人群中普遍存在艾滋病、HCV等血源传染性疾病流行的风险,加强对吸毒人群的监测和防病知识宣传教育及行为干预,有利于控制诸如艾滋病、HCV等血源性疾病的传播和蔓延。     

南宁市吸毒人群丙肝抗体阳性率检测分析

目的通过对南宁市吸毒人群丙型肝炎(抗-HCV阳性率)感染情况的检测分析,探讨吸毒人群传播丙肝的危险性,为预防和控制吸毒人群传播丙肝提供科学依据.方法采用酶联免疫吸附法(ELISA)检侧449例吸毒人员和400例普通人群的血清丙肝抗体(抗一HCV).结果吸毒组血清抗-HCV阳性率91.09%,对照组血清抗-HCV阳性率0.25%,吸毒人员丙肝阳性率显著高于对照组(χ2=699.09, P<0.01).共用注射器具吸毒者HCV阳性率(95.57%)显著高于不共用注射器具吸毒者(52.63%)(χ2=47.38, P<0.01).结论吸毒人群是丙肝病毒的重要携带者和传染源,是丙肝防治的重点人群,应加强对吸毒人群的管理和干预,防止丙肝在人群之间的传播.     

蚌埠市吸毒人群丙肝抗体调查分析

目的:了解蚌埠市吸毒人群丙型肝炎感染情况,探讨吸毒人群传播丙肝的危险性。方法:应用酶联免疫吸附法(ELISA)检测153例吸毒人员和130例普通人员的血清丙肝抗体(抗-HCV)。结果:吸毒组血清抗-HCV阳性101例,感染率66.0%,对照组血清抗-HCV阳性2例,阳性率1.5%。吸毒人群丙肝病毒感染率是普通人群的44倍。结论:吸毒人群是丙肝病毒的重要携带者和传染源,应加强吸毒人群的管理,进一步推广关沙酮替代疗法。     

广西中越边境2012—2019年吸毒人群HIV和HCV感染状况及影响因素

目的 了解广西中越边境地区吸毒人群中HIV、丙肝病毒（HCV）及HIV/HCV合并感染情况及其影响因素,为在该人群中开展高危行为干预提供参考依据。方法 2012—2019年间每年4—6月,采用国家统一制定的问卷对广西中越边境哨点监管场所、社区和美沙酮门诊最近1个月吗啡尿检阳性者开展连续横断面调查,并采集调查对象血液标本进行HIV和HCV抗体检测。结果 2012—2019年共监测12 842名毒品使用者。HIV感染率为3.84%,HCV抗体阳性率为43.34%,HIV/HCV合并感染率为3.14%。HIV、HCV及HIV/HCV合并感染率整体上呈逐年下降的趋势。不同行为特征的吸毒人群感染情况不同。Logistic回归分析显示,女性、小学学历、有注射吸毒史是感染HIV的危险因素。年龄≥20岁、离异或丧偶、除汉族和壮族外的其他少数民族、传统毒品和混合毒品使用者、有注射毒品史是感染HCV的危险因素。而女性、小学文化、有注射毒品史是HIV/HCV合并感染的危险因素。结论 广西边境吸毒人群整体HIV感染率和HCV抗体阳性率较高,HIV/HCV合并感染率较低,新型毒品使用者比例呈上升趋势。提示需针对女性、高年龄组及有注射吸毒史的吸毒人群开展有效干预措施。     

许昌市2002-2010年吸毒哨点艾滋病性病监测情况

目的了解许昌市吸毒人员的高危行为和艾滋病及性病的感染状况,为制定艾滋病性病的预防控制措施提供依据。方法按照国家艾滋病哨点监测实施方案的要求,对监测期间新入所的吸毒人员进行行为学调查和艾滋病、梅毒、丙肝血清抗体检测。结果口吸毒者及注射吸毒者分别占吸毒人员总数的93.2%和6.80%;该吸毒人群中HIV抗体阳性率为0.41%,梅毒感染率为1.04%。结论许昌市吸毒人员艾滋病、性病感染危险因素广泛存在,应加强针对该人群的高危行为干预。     

河北赵县献血村丙肝感染情况调查

目的了解1985年左右参与非法献血人数较多的赵县前大章乡城郎村村民受HCV感染的现状,为当地丙肝防治提供依据。方法采用横断面调查方法 ,将户每位成员基本情况录入数据库。采集每位村民4mL血清,现场分离血清,并检测血清ALT、抗-HCV抗体。结果河北赵县献血村人群抗-HCV阳性率为26.72%;感染人群主要集中在40~60岁之间;献血员抗-HCV阳性率高于非献血员;不同献血类型HCV感染情况不同,混合献血感染几率最大。抗-HCV阳性率随混合献血次数的增加而升高。结论河北赵县献血村HCV感染情况较严重,人群抗HCV感染率远高于全国水平。     

岑溪市394例吸毒人员HIV、HCV、TP感染情况分析

目的 了解掌握岑溪市吸毒人群的艾滋病病毒、丙型肝炎病毒、梅毒螺旋体感染情况,为该市艾滋病防治工作提供依据.方法 采用流行病学描述性研究方法对岑溪市394名吸毒人员人口、行为学资料分布情况分析;并开展艾滋病、丙肝、梅毒抗体检测,分析感染情况.结果 394例吸毒人员抗HIV、HCV、TP抗体阳性率分别为5.33％、80.96％、3.55％.30～岁组的HCV感染率高于≥40岁组.TP感染率女性高于男性.共针静脉注射吸毒者HCV感染率明显高于非共针静脉注射吸毒者.结论 岑溪市吸毒人群HIV、HCV、TP感染率较高,是重要的传染源之一,应加强对吸毒人群的监测、高危行为干预和健康教育.     

2010～2011年永济市吸毒人员艾滋病哨点监测结果分析

目的了解我市吸毒人群中艾滋病、梅毒和丙肝的感染率变化趋势以及吸毒行为的变化情况,以获得我市艾滋病流行趋势及危险因素,及时总结我市艾滋病哨点监测工作经验及监测工作中存在的问题,更好地有针对性地开展艾滋病宣传教育及防治工作。方法按照中国疾病预防控制中心性艾中心艾滋病哨点/丙肝哨点监测实施方案要求进行监测。结果 2010~2011年我市监测的吸毒人员均为男性,青壮年、已婚者居多,多数吸毒者为初中以下文化,吸毒人群的吸毒方式以口吸为主,大都吸食海洛因。2010年监测的421例吸毒人员中有商业性行为占14.01%,静脉注射吸毒者占16.15%,共用针具者占19.12%,HIV抗体阳性1例,阳性检出率为0.24%,梅毒抗体检测阳性8例,检出率为1.90%,丙肝抗体阳性46例,检出率为10.93%。2011年监测的411例吸毒人员中有商业性行为者占21.41%,静脉注射吸毒者占22.87%,共用针具者占37.23%,未检出HIV抗体阳性者,梅毒抗体检测阳性23例,检出率为5.59%,丙肝阳性56例,检出率为13.63%。结论我市被调查的吸毒人群中艾滋病感染率较低,梅毒、丙肝感染率较高,呈上升趋势;静脉注射吸毒、共用针具、商业性行为等危险行为发生率有所升高。在吸毒人群中加强艾滋病防治知识,进行健康教育和行为干预刻不容缓。     

包头市昆区2012年在押吸毒人群艾滋病监测结果分析

目的:了解包头市昆区吸毒人群艾滋病流行状况和流行因素,分析吸毒人群艾滋病流行趋势,为艾滋病疫情的估计和预测提供信息,为制定艾滋病防治策略和干预措施及效果评价提供科学依据。方法:采用统一的调查问卷,对监测期内在押的吸毒人员进行面对面的问卷调查,同时对每一个调查对象采集静脉血3～5 mL进行HIV抗体、HCV抗体、梅毒抗体检测。结果:共检测在押吸毒人员403人,HIV抗体阳性者2例,阳性率0.50%;HCV阳性者105例,阳性率26.05%;梅毒阳性者8例,阳性率1.99%。结论:包头市昆区吸毒人群的HIV感染率较低,但存在高危行为,应加强吸毒人员艾滋病、性病、肝炎知识的宣传教育及行为干预等工作,扩大综合干预覆盖面,提高干预工作质量,阻止艾滋病由高危人群向一般人群传播,防止HCV、梅毒的蔓延。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.