经皮扩张气管切开术在外科危重病人中的临床应用价值

目的　通过比较开放性气管切开术 (OT)和经皮扩张气管切开术 (PDT)在 SICU的应用情况来评价PDT的临床应用价值。方法　采取前瞻性随机性研究方法比较 PDT(Portex法 )组和 OT组在住院期间的并发症发生率、与操作相关的死亡率和操作时间。结果　 PDT组的并发症发生率明显低于 OT组 (P<0 .0 5 )。 OT组与操作相关死亡率为 1.1% ,PDT组则没有与操作相关的死亡情况发生。 OT组平均操作时间为 2 3.8± 12 .9分钟 ,PDT组为 9.0± 4.1分钟 ,PDT操作时间明显比 OT短 (P<0 .0 1)。结论　经皮扩张气管切开术可在床边进行 ,操作时间短 ,并发症少 ,明显优于传统开放性气管切开术 ,尽管其一次性消耗费用较高 ,但依然在外科危重病人中有广泛的应用价值。     

经皮扩张与常规气管切开术在重型颅脑损伤昏迷病人中的应用比较

目的:通过比较开放式气管切开术(OT)和经皮扩张气管切开术(PDT)在重型颅脑损伤昏迷病人中的应用情况来评价PDT的临床应用价值.方法:采取前瞻性随机性研究方法比较PDT组和OT组在住院期间的并发症发生率及操作时间.结果:PDT组的并发症发生率明显低于OT组(P＜0.05).PDT组平均操作时间为(7.8±2.9) min,OT组为(21.3±4.2) min.PDT组操作时间明显比OT组短(P＜0.01).结论:PDT操作简单快速,并发症少,可由神经外科医师独立完成,在重型颅脑损伤昏迷病人中有较广泛的应用价值.     

经皮扩张气管切开术在危重患者抢救中的应用

目的 探讨经皮扩张气管切开术在基层医院危重病患者救治中的临床应用价值.方法 回顾性分析行气管切开术的危重病例77例,根据手术方法不同分为经皮扩张气管切开术(PDT)组(31例)和传统气管切开术(OT)组(46例),比较两组手术患者在手术时间、切口大小、出血量、并发症发生率的差异.结果 PDT组手术时间、切口长度、出血量均小于OT组(P<0.05).PDT组出现皮下气肿1例;OT组出现皮下气肿4例,切口出血3例,气管导管脱出1例.PDT组并发症发生率小于OT组(P<0.05).结论 PDT简单、快捷,并发症少,在基层医院危重病患者救治中值得推广应用.     

经皮扩张气管切开术在急危重症病人中的应用

目的 讨论经皮扩张气管切开术（PDT）在危重病患者中的应用.方法 应用PDT技术40例,对照与同期传统开放性气管切开术（OT）40例.对照两组在手术时间、切口大小、术中出血、切口愈合时间及各种并发症发生率之间的差异.结果 PDT组成功进行手术39例,操作时间为（7.35±2.45）min;切口长度为（1.62±0.35）cm;手术中出血量（6.15±2.30）ml,手术后并发症发生率低予传统开放性气管切开术组.结论 PDT在操作安全性、简单、快速、组织损伤少、愈合瘢痕小、并发症发生率低等方面要好于OT,适合对危重患者的应用.     

经皮扩张气管切开术在ICU中的临床应用价值

目的：通过比较传统开放性气管切开术（OT）和经皮扩张气管切开术（PDT）在ICU中的应用情况来评价PDT的临床应用价值。方法：将84例需要气管切开的危重患者随机分成两组，即传统开放性气管切开组（OT组）和经皮扩张气管切开组（PDT组），各42例。OT组行传统开放性气管切开术，PDT组行经皮气管切开术，观察手术时间、切口大小、术中出血量、伤口愈合时间及术后并发症。结果：PDT组手术时间为（8．35±1．76）min．切El大小为（1．27±0．20）cm，术中出血量为（6．03±1．70）ml，伤口愈合时间为（4．5±0．5）d，明显低于对照组（P〈0．01），术后并发症发生率也低于对照组。结论：经皮扩张气管切开术操作简单，安全快速，出血量少，创伤小，伤口愈合时间快，并发症少，明显优于传统开放性气管切开术，在ICU危重患者抢救中，有广泛的应用价值。     

经皮扩张气管切开术与气管切开术的临床应用对比

目的 探讨危重患者行经皮扩张气管切开术的可行性和安全性.方法 总结本院重症监护病房(ICU)中气管切开患者共32例,随机分为经皮扩张气管切开术(percutaneous dilatational tracheostomy,PDT)组16例,外科气管切开术(open tracheostomy,OT)组16例.比较两组术中切口大小、手术时间及出血量,术后切口感染、气管闭合时间、切口闭合时间及切口渗血量.结果 PDT组与OT组相比,PDT组操作切口小、手术时间短、出血量少、切口感染率降低、术后渗血少、气管闭合时间及切口闭合时间缩短.结论 经皮扩张气管切开术(PDT)与外科气管切开术(OT)相比,具有安全、操作简单、手术时间短、并发症少等优点,尤其适用于危重患者的抢救治疗.     

经皮气管旋切术在危重患者人工气道建立中的应用价值

目的:探讨经皮气管旋切术(PDT)在危重患者人工气道建立中的应用价值.方法:38例患者行PDT,观察其手术情况,围手术期及后期并发症,切口愈合时间,手术安全性等,并与传统的开放式气管切开术(OT)进行比较.结果:PDT组的手术时间(9.5±6.3)分钟,术中出血量(11±9.5)ml,切口长度(1.45+0.15)cm,切口愈合时间(4±2)d;OT组手术时间(26.60±8.15)min,术中出血量(25.5±12.2)ml,切口长度(4.1±0.32)cm,切口愈合时间(9±2)d.两组上述指标比较差异均有统计学意义(P＜0.05).结论:PDT组手术时间短,愈合快,出血量少,围手术期和后期并发症发生率低,该术式是一种微创的、快捷的急救技术,适用于需建立人工气道的危重患者.     

经皮扩张气管切开术在综合ICU中的临床应用

目的:探讨经皮扩张气管切开术(Percutaneous dilational tracheostomy,PDT)在综合ICU危重患者人工气道建立中的临床应用价值。方法:选取本院综合ICU在2011年3月-2013年10月开展PDT术的48例患者,并选取同期行传统气管切开术(Open tracheostomy,OT)的45例患者作为对照,观察比较两组术中、术后的一般情况及并发症等方面的差异。结果:PDT组的手术时间明显短于OT组,出血量明显少于OT组,切口大小明显小于OT组,差异均有统计学意义(P0.05);PDT组的并发症发生率6.25%明显低于OT组的40.00%,差异有统计学意义(P0.05)。结论:经皮扩张气管切开术具有术中及术后出血量少、创伤小、并发症少、手术操作过程简单、手术时间短等优点,适合于综合ICU的危重患者的应用,值得临床推广。     

纤维支气管镜引导下经皮扩张气管切开术在ICU中的应用

目的：对比分析经皮扩张气管切开术（PDT）与常规气管切开术（OT）在ICU中的临床应用。方法：选取ICU需气管切开机械通气的40例患者,随机分为PDT和OT两组。PDT组20例行经皮穿刺气管切开术,OT组20例行常规气管切开术。结果：PDT组平均手术时间（9±4.60）min,出血量（8.6±3.0）ml,OT组平均手术时间（36.5±11.5）min,出血量（25.4±4.5）ml,两组比较差异有统计学意义（P〈0.01）。术后并发症发生率较常规气管切开术无增多倾向（P〉0.05）。结论：经皮穿刺气管切开术与常规气管切开术比较,具有手术时间短、切口小、出血量少等优点,术后并发症未见增多,适合在急救中普及应用。     

EICU重症患者应用经皮扩张气管切开术后的效果观察

目的 观察经皮扩张气管切开术(percutaneous dilational tracheostomy,PDT)在急诊重症监护室(emergency intensive care unit,EICU)重症患者中应用效果.方法 54例行气管切开术的EICU重症患者中28例行经皮扩张气管切开术(percutaneous dilational tracheostomy,PDT),另26例行传统的开放气管切开术(open tracheostomy,OT).观察2组手术经历时间、切口大小、术中出血量、拔管后切口愈合时间及术后并发症情况.结果 PDT组手术经历时间、切口大小、术中出血量、拔管后切口愈合时间明显小于或短于OT组,术后并发症发生率也明显低于OT组.结论 EICU危重患者的抢救治疗措施中,PDT较OT更具有优越性.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.