聚丙撑碳酸酯增韧环氧树脂的研究

研究了聚丙撑碳酸酯（ＰＰＣ）对环氧树脂（ＥＰ）的改性作用、加入２０～３０Ｐｈｒ的ＰＰＣ，环氧树脂力学性能可以大幅度提高，粘接剪切强度为１２３３ＭＰａ，冲击强度为１６．７８ｋＪ／ｍ２；而纯环氧树脂固化物，其剪切强度为９．３６ＭＰａ，冲击强度为９．９９ｋＪ／ｍ２。ＳＥＭ和ＤＳＣ观测表明ＰＰＣ／ＥＰ体系呈两相结构。     

亚微米级无机抗菌剂的有机湿法改性

采用硬脂酸与钛酸酯偶联剂联用对超细亚微米级载银TiO2进行了表面改性，使表面由亲水性变为亲油性，并探讨了改性前后的表面结构。用IR、TEM等多种手段表征其改性效果，用X射线荧光光谱测定了改性对银离子含量的影响。结果发现硬脂酸和钛酸酯成功包覆在粉体表面，包覆量可达0.92%，使粉体表面性质由亲水变为亲油；但用振荡烧瓶法测定改性前后抗菌剂对大肠杆菌的抗菌率，仍然达到99.7%。     

甲阶酚醛树脂的贮存稳定性

甲阶酚醛树脂在贮存过程中容易自缩聚,稳定性低。采用两种方法对其进行改性：一种是引入氯丙烯以降低羟甲基活性,另一种是合成高邻位酚醛树脂并加入聚乙二醇。通过红外光谱（FT-IR）、差示扫描量热法（DSC）分别表征了改性前后树脂的基团变化、热性能,并进行了固化动力学分析,考察了酚醛树脂的黏度变化以研究其贮存性能。研究表明：成功地运用这两种方法合成了改性树脂,且热分析结果说明羟甲基的活性有所减弱;固化动力学结果表明树脂活化能变化较小,说明树脂贮存稳定性提高且对固化影响不大,烯丙基改性将酚醛树脂的贮存期由30 d提高到108 d,聚乙二醇改性后也可以贮存至108 d。     

氯丙烯改性甲阶酚醛树脂的性能

针对甲阶酚醛树脂贮存稳定性低、耐碱性差的缺点,用氯丙烯对其进行改性。通过红外光谱分析（FT-IR）、热重分析（TGA）、差示扫描量热法（DSC）、动态力学分析（DMA）等手段表征了改性前后酚醛树脂的基团变化、热性能和动态力学性能。研究表明：烯丙基团成功地接入了酚醛树脂,并使酚醛树脂的贮存期由原来的30 d提高到了102 d;固化物玻璃化转变温度（T_g）从改性前的58℃提高到改性后的122℃;耐腐蚀性和耐热性也均有一定程度的提升,力学性能则随着烯丙基质量的增加呈现先增强后减弱的趋势。     

聚氨酯改性氟代聚丙烯酸酯的合成、表征与膜形态

在二月桂酸二丁基锡(T-12)作用下,将1,6-已二异氰酸酯(HDI)与聚乙二醇(PEG-200)在70℃反应合成—NCO封端的聚氨酯预聚体(PU),然后滴加甲基丙烯酸十二氟庚酯(RfAA)、丙烯酸羟丙酯(HPAA)和偶氮二异丁腈(AIBN)在甲基异丁基甲酮(MIBK)溶液中聚合反应4～6 h,再经丁酮肟(EtAO)封端,制得了一种新型聚氨酯改性氟代聚丙烯酸酯易去污整理剂(FPUA)。用红外光谱(IR)、核磁共振氢谱(1H-NMR)、核磁共振碳谱(13C-NMR)、原子力显微镜(AFM)和扫描电镜(SEM)等对FPUA的结构、成膜形态及应用性能进行了研究。结果表明:FPUA在亲水性纤维织物和单晶硅表面均能形成非单一结构的疏水膜。该膜附着在纤维表面,能使处理后织物表面水的静态接触角达到146.5°,色拉油的接触角达到132°,且易去污效果良好。     

改性UHMWPE纤维/乙烯基酯树脂复合材料的研究

超高分子量聚乙烯纤维在过氧化物引发下，通过硅烷进行接枝改性。研究了改性纤维／乙烯基酯树脂复合材料的界面性能。采用层间剪切强度、扫描电镜、红外光谱(ATRIR)及浸润性测试等分析手段表征了接枝改性的效果。结果表明，经过硅烷接枝改性，改善了超高分子量聚乙烯纤维对乙烯基酯树脂的浸润性，提高了纤维与基体之间的粘结性，使复合材料的层间剪切强度大幅度提高。     

99Tcm-MIBI乳腺显像诊断乳腺癌受试者操作特性分析

目的用受试者操作特征（ROC）分析方法评价99Tcm甲氧基异丁基异腈（MIBI）显像诊断乳腺癌的评判方法。方法回顾性分析经手术与病理证实65例乳腺肿瘤患者，术前行99Tcm-MIBI平面显像，分别计算肿瘤与健侧对应部位（T／N）、肿瘤与胸骨（T／S）、肿瘤与心脏（T／H）的放射性比值，用受检者工作特性（ROC）曲线评价T／N、T／H和T／S诊断乳腺癌的价值，确定最佳临界点。结果（1）T／N的ROC曲线下面积（Az）和T／H、T／S、的ROC曲线下面积（Az）明显不同（P〈0．01），差异有统计学意义。T／N在诊断乳腺癌的价值最高明显优于T／H和T／S。（2）T／N比值在1．2～1．3之间准确性最高，能兼顾灵敏度和特异度。结论99Tcm-MIBI乳腺显像诊断乳腺癌较合适的评判方法为选择T／N为判断指标，比值取1．2～1．3。     

以切口-下端皮肤供皮在乳腺癌手术中的应用

1987年以来，对T3及部份T2乳腺癌的根治手术，在保证离癌肿3～5 cm皮肤要切 除的基础上，另外先在设计切口下端取中厚游离皮片用于手术创面的植皮。取得满意效果，报告如下。 1 资料与方法 1.1 临床资料本组29例全部为女性，年龄38～64岁，平均年龄46．8岁。病程11周～4年。肿瘤直径4～6 cm 11例，6～9 cm18例；N18例，N221例；浸润性导管癌17例，单纯癌10例，炎性乳癌2例。     

60Co-γ射线原位辐射聚合法制备近红外吸收滤光片

设计并合成了2个可溶性的金属酞菁类化合物（A和B）作为近红外吸收染料。其中,染料A是铜酞菁衍生物,在N,N-二甲基甲酰胺（DMF）中的最大吸收波长为710 nm,染料B是钒氧萘酞菁衍生物,在DMF中的最大吸收波长为800 nm。将它们加入到丙烯酸酯单体中,采用⁶⁰Co-γ射线原位辐射聚合的方法制得了交联型聚丙烯酸酯近红外滤光片。采用紫外-可见-近红外吸收光谱仪测定聚丙烯酸酯滤光片的吸收光谱曲线,结果表明：染料A和B均能均匀地分布在丙烯酸酯聚合物中,且聚丙烯酸酯近红外滤光片在DMF、丙酮、甲苯等溶剂中几乎不溶。在聚丙烯酸酯滤光片中,染料A与B的吸收峰范围分别为620~780 nm和700~870 nm。制备的交联型滤光片对上述波长范围的近红外光有较好的屏蔽作用,耐溶剂性能良好。     

静滴清开灵致面部皮丘疹1例

1 病历报告 患者，男，78岁，因急性上呼吸道感染于2006年7月18日入院，查体：T38．7℃，P88次／min，R20次／min，BP 120／83mmHg；实验室检查血常规：Hb114g／L，WBC7．84×10^9／L，N0．52，L0．40，尿常规、便常规均无异常；X线胸片示：心肺膈未见异常。入院当日给予清开灵注射液30ml加入生理盐水250ml内静滴后，患者出现面部轻度痒感，未在意。[第一段]     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…