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1.
功能性消化不良(functional dyspepsia,FD)是指非器质性病变引起的一组上腹痛、上腹胀、早饱、嗳气、食欲不振、恶心、呕吐等上腹部不适症候群。欧美的流行病学调查表明,普通人群中有消化不良症状者占19%-41%。我国某市一份调查报道,FD占该院胃肠专科门诊患者的50%。笔者自2000年1月-2006年12月采用中药结合针灸治疗FD98例,现报道如下。  相似文献   

2.
李丕成 《基层医学论坛》2009,13(20):602-603
功能性消化不良是指持续或反复发作的,包括上腹痛、上腹饱胀、上腹胀感、早饱、嗳气、恶心、呕吐等上腹部症状的一组临床症状。经检查排除可引起这些症状的器质性疾病时,这一临床症状便称为功能性消化不良(FD),发病率高,普通人群有消化不良症状者达19%~41%。门诊资料统计,FD患者占我院消化门诊40%以上。除以上消化系统症状外,多数患者伴有失眠、焦虑等症状,  相似文献   

3.
刘放明 《中原医刊》2004,31(3):38-39
功能性消化不良(FD)发病率高,国外报道^[1],FD在总人群中患病率20%,在普通门诊中约占20%~40%,在消化专科中约为60%~70%。严重影响了患者的工作、学习和生活。本文就多塞平与西沙必利联合治疗FD40例取得满意效果,报道如下。  相似文献   

4.
百忧解治疗功能性消化不良疗效观察   总被引:1,自引:0,他引:1  
罗正义 《河北医学》2004,10(10):928-928
功能性消化不良(FD)发病率高。国外报道,FD在总人群中患病率20%。在普通门诊中约占20%~40%,在消化专科中约为60%-70%。通过心理调查,发现这部分人有较明显的焦虑等精神心理障碍,严重影响了患者的学习、工作和生活。我们于2001年11月至2003年6月用百忧解治疗FD98例,取得较满意疗效.现报告如下。  相似文献   

5.
功能性消化不良的精神心理因素及抗抑郁治疗   总被引:5,自引:0,他引:5  
韩志斌 《医学文选》2003,22(2):143-145
目的 探讨功能性消化不良(FD)与精神心理因素的关系及抗抑郁治疗对其的疗效。方法 对100名正常人和100例FD患者进行抑郁自评量表(Zung)评分;采用自身对照的临床研究,将伴有抑郁症状的FD患者随机分为A、B两组,分别给予抗消化不良、抗抑郁治疗,疗程为6—8周,两组治疗后再行量表评分。结果 Zung量表评分显示39%的FD患者有抑郁情绪,正常人与FD患者的量表评分比较有显著性差异(P<0.01);两组消化不良控制总有效率分别是45.0%、84.2%,有显著性差异(P<0.01)。结论 FD与精神心理因素关系密切,抗抑郁药治疗能有效地改善FD患者的抑郁和消化不良症状。  相似文献   

6.
功能性消化不良(functional dyspepsia,FD)是临床常见的症候群,发病率高,占消化道疾病患者的20%~40%,欧美流行病学调查发现,人群消化不良发病率为21%~40%,其中40%~70%为FD。不仅影响患者的生活质量,而且构成相当高的医疗费用,患者常主诉上腹不适、隐痛、早饱、上腹胀满、食欲不振等消化不良症状,但胃镜、B超等检查未能显示结构上的明显异常。  相似文献   

7.
功能性消化不良(FD)是指具有上腹痛,上腹胀,早饱,嗳气,食欲不振,恶心,呕吐等不适症状,经检查排除引起这些症状的器质疾病的一组临床综合征。症状可持续或反复发作,病程一般规定为>1个月或在12月中累计超过12周。FD是临床上最常见的一种功能性胃肠病,欧美的流行病学高查表明,普通人群中有消化不良症状者占19%~41%,我国某市一份调查报道,FD占该院胃肠病菌专科门诊患者的50%。FD不仅影响患者的生活质量,而且构成 相当高的医疗费用,因此已逐渐成为现代社会中一个主要的医疗保健问题。  相似文献   

8.
消化不良(dyspepsia)可有两部分构成,即器质性消化不良(organic dyspepsia)与功能性消化不良(function dyspepsia,FD)。消化不良是一个十分常见的症状群,它比消化性溃疡还要多2~8倍,在消化疾病专科门诊中约占全部病人20%~40%。众所周知消化系统疾病、全身疾病乃至某些药物等原因引起的消化不良,称为器质性消化不良;而相当一部分患者虽经过“全面检查”,也未能发现足以解释症状的器质性疾病,称为FD。  相似文献   

9.
陈成活  黄印 《医学文选》2005,24(4):568-569
功能性消化不良(FD)是常见的上消化道症候群,以慢性或复发性上腹部疼痛或不适为主要表现,其病因和发病机制至今尚未明了,发病率高达20%--30%,占消化道门诊患者的50%。国外研究认为1/3的人群患过此病,占门诊总数的20%-30;治疗上以症状治疗为主,目前西药对本病治疗效果尚不理想。我科1999年以来用中药平胃散加味治疗FD40例,并与40例西药对照组进行比较,取得良好的疗效,现报告如下。  相似文献   

10.
功能性消化不良(functional dyspepsia,FD)是指具有上腹痛、上腹胀、早饱、嗳气、食欲不振、恶心、呕吐等上腹不适症状,经检查排出引起这些症状的器质性疾病的一组临床综合征,症状可持续或反复发作,症程一般规定为超过1个月或在1年中累计超过12周。FD是临床上最常见的一种功能性胃肠病。据国内资料统计:占正常人群的18.9%,占消化内科病人数的40%,占胃肠专科门诊患者的1/3^[1]。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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