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1.
目的 探讨CT在胃肠道间质瘤诊断中的价值.方法 回顾性分析我院近期收治的30例经手术病理证实为GIST的CT表现临床资料.结果 30例GIST中,良性6例,恶性24例;发生于胃14例;小肠8例;十二指肠3例;小肠系膜5例.CT表现为病灶密度不均匀,增强后明显不均匀强化.结论 CT检查对胃肠道间质瘤的定位和定性诊断具有重要价值.  相似文献   

2.
胃肠道间质瘤的CT诊断与临床病理分析   总被引:3,自引:2,他引:1  
目的 探讨胃肠道间质瘤(GIST)的CT表现,以提高对GIST的诊断水平.方法 搜集经手术和病理证实的胃肠道间质瘤32例,回顾性分析其CT和病理表现.所有病例均行CT平扫及增强扫描.结果 32例肿瘤均为单发,位于胃部17例,空肠和回肠7例,结肠及直肠3例,食管1例,十二指肠和肠系膜各2例.良性9例,恶性23例.CT表现为黏膜下富血供性肿块,肿瘤倾向于腔外生长,可有囊变、坏死及钙化.双期增强扫描见静脉期较动脉期强化显著.结论 CT是GIST的主要影像学检查方法 ,CT表现有一定的特征性,对胃肠道间质瘤的定位和定性判断以及鉴别诊断有重要价值,但定性诊断需依赖免疫组化和电镜检查.  相似文献   

3.
目的探讨胃肠道间质瘤(gastrointestinal stromaltumor,GIST)的螺旋CT表现及临床诊断价值。方法回顾性分析经病理证实的30例胃肠道间质瘤的螺旋CT表现。结果本组中食管间质瘤1例,胃间质瘤15例,小肠间质瘤7例,直肠间质瘤1例,结肠系膜间质瘤1例,腹膜后间质瘤1例,肿块太大难以确定来源部位4例(主要位于腹腔及盆腔)。低度危险5例,中度危险6例,高度危险19例。低度危险的GIST为类圆形的肿块,密度较均匀;高度恶性肿瘤直径均〉5cm,强化欠均匀,坏死囊变多,形态不规则;中度危险的GIST大小形态无特征性。结论对胃肠道间质瘤的螺旋CT检查有助于发现肿块,准确定位,帮助判断肿瘤的良恶性程度,对其早期发现,及时治疗和判断预后有重要意义。  相似文献   

4.
目的 对间质瘤(GIST)的影像学表现进行比较,提高该肿瘤的诊断正确率.方法 对经病理证实的32例病例进行影像学表现比较分析.结果 32例GIST中,恶性23例,良性7例,交界性2例.各种影像表现中肿瘤大小、有无分叶、钙化与良性差别较明显,而边界、血供丰富程度无明显差别.结论 各种影像学手段对检出GIST各有利弊,良恶性区别也不甚明显,确诊仍有赖于病理学检查.  相似文献   

5.
目的探讨胃肠间质瘤(gastrointestinal stromal tumor,GIST)CT诊断价值。方法回顾性分析39例经手术病理和免疫组织化学证实的GIST患者的临床及CT检查资料,并将CT表现与病理诊断进行对照。结果39例GIST中,良性共9例,恶性共30例。发生在胃肠道26例恶性19例,发生在胃肠道外13例恶性11例;肿瘤5cm组14例恶性7例,肿瘤≥5cm组25例恶性23例;有囊变坏死30例恶性29例,无囊变坏死9例恶性1例;11例有转移均为恶性,28例无转移恶性19例。GIST的发病部位、大小、有无囊变坏死及转移对肿瘤的良恶性的鉴别有统计学差异(P0.05)。发生在胃肠道外的GIST恶性程度高,肿瘤≥5cm组恶性程度较高,且肿瘤的大小与肿瘤恶性程度呈显著正相关,有囊变坏死及转移的GIST恶性程度高。结论CT检查对GIST的定位、定性诊断有重要价值,多种CT征象有助于对GIST良、恶性做出准确判断。  相似文献   

6.
目的探讨胃肠道间质瘤CT检查的临床价值。方法对30例经证实为胃肠道问质瘤患者的CT表现、病理特征及随访情况进行回顾性分析。结果30例GIST患者中病变位于胃部17例,小肠8例,结肠5例。良性16例,恶性14例。肿瘤病理危险度评估:极低危8例(27%)、低危7例(23%),中危6例(20%),高危9例(30%)。CT影像、预后与病理对照分析.肿瘤形态不规则、浸润性生长、严重瘤内坏死、强化程度和较差预后更多见于高危险度胃肠道GIST(P〈O.05):肿瘤生长部位与GIST的病理危险度之间没有显著相关性(P〉0.05)。结论CT扫描对GIST诊断有特征性影像表现.在定位、定性等方面有较大的临床价值。  相似文献   

7.
目的 探讨胃肠道间质瘤(GIST)的CT表现.方法 回顾性分析10例经手术病理证实的GIST的CT表现.结果 CT主要表现为胃或肠腔的偏心性狭窄、局部倾向于向外生长的肿块、肿块内见出血或不规则坏死区,CT增强扫描肿块不均匀明显强化.结论 CT影像学表现与病理特点一致,对临床诊断有帮助.  相似文献   

8.
目的 探讨多排螺旋CT对胃肠道间质瘤的诊断价值.方法 回顾性分析2005~2008年共30例经手术及病理证实的胃肠道间质瘤的CT表现,所有患者术前均行CT平扫和增强扫描.结果 30例胃肠道间质瘤发生在胃16例,十二指肠5例,空肠5例,回肠4例;良性5例,潜在恶性4例,恶性21例;多表现为边界清楚的圆形或类圆形肿块.良性GIST密度均匀,强化均匀;恶性者密度不均匀,强化不均匀.结论 CT能准确显示GIST的部位、形态和大小,并可初步鉴别肿瘤的良恶性,具有重要临床价值.  相似文献   

9.
目的:探讨不同生长类型胃肠道间质瘤(GIST)与病理危险度的关系,评价CT对GIST诊断及预后判断的价值。方法:回顾性分析26例经病理证实的GIST的多排螺旋CT资料。结果:26例GIST中,发生于胃14例,小肠7例,胃肠外5例;其中跨壁型3例,壁内型3例,壁外型10例,腔内型5例,胃肠外型5例;不同病理分级的GIST,肿瘤生长类型有统计学差异(P0.05),生长部位无统计学差异(P0.05)。结论:不同生长类型GIST的影像学表现可以在一定程度上提示其恶性程度。  相似文献   

10.
胃肠道间质瘤的CT诊断   总被引:1,自引:0,他引:1  
目的:探讨胃肠道间质瘤(GIST)的CT表现特征及诊断价值。方法:回顾性分析经手术和病理证实的14例胃肠道间质瘤患者的CT影像学资料和临床资料。结果:肿瘤位于胃部9例,十二指肠1例,空肠2例,回肠1例,胃肠道外1例。14例中恶性7例,交界性4例,良性3例。CT表现为腔内外肿块,最大径范围1~23cm,<5cm者5例,≥5cm者9例,呈类圆形、不规则形,密度均匀及不均匀,增强后实性部分中度强化至明显强化。瘤内点状钙化灶3例。结论:GIST的CT表现具有一定特点,对诊断有重要价值。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

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