广西百色市首例人感染H7N9禽流感病例流行病学调查

目的对2017年百色市首例人感染H7N9禽流感病例进行流行病学调查,为今后防控人间禽流感疫情提供依据。方法采用流行病学调查方法对病例诊疗经过、暴露因素和实验室检测资料进行分析。结果确诊的人感染H7N9禽流感病例有明确的家禽接触史,病人下呼吸道分泌物H7N9核酸检测呈阳性,购买禽类的摊点外环境检出H7N9核酸阳性样本。结论病例感染来源可能与其购买家禽周边的农贸市场外环境暴露有关,未发现人传人现象。应加强宣传教育,提高医疗机构临床医生的诊疗水平,及时发现及治疗。     

广州市番禺区人感染H7N9禽流感流行病学和外环境监测

目的分析广州市番禺区人感染H7N9禽流感的流行特征和外环境监测结果,为防控H7N9禽流感工作提供科学依据。方法采用流行病学个案调查与描述性分析方法,收集2014-2015年番禺区出现的人感染H7N9禽流感确诊病例的流行病学调查资料,以及全区外环境监测点的监测资料。结果 2014-2015年番禺区共确诊6例人感染H7N9病例,均在2月份发病,死亡4例,发病前有活禽市场接触史5例;共采集外环境标本3 031份,检测阳性率为6.17%,肉菜市场、禽类批发市场、禽类养殖场检测阳性率分别为7.22%、2.04%、0.00%,差异有统计学意义(P0.05);外环境标本阳性检出率与病例发病时间分布上一致。结论冬春季节是本地人感染H7N9禽流感易发季节,活禽市场暴露是危险因素,规范活禽交易是防控人感染H7N9禽流感的关键。     

贵州省三都县1例人感染H7N9禽流感病例的流行病学调查

目的通过对贵州省三都县1例确诊的人感染H7N9禽流感病例进行流行病学调查,为禽流感科学防控提供依据。方法采用现场流行病学调查方法,调查病例发病经过、感染来源、传播途径等,并在病例救治痊愈后对病例进行回顾性访谈。结果 2017年贵州省新增1例确诊人感染H7N9病例,病人有活禽市场暴露史,并在其暴露活禽市场摊位外环境标本检出3份H7N9病毒核酸阳性。结论活禽市场暴露是人感染H7N9禽流感的风险因素,加强活禽市场的监管是禽流感防制的重要工作。     

广东省江门市首例人感染H7N9禽流感病例的流行病学调查

目的为了及时有效地控制人感染H7N9禽流感疫情,防制疫情扩散蔓延。方法采用流行病学调查方法,调查病例的发病经过、可能的感染来源、传播途径及暴露因素等,医学观察患者的密切接触者。结果确诊l例人感染H7N9禽流感病例,经抢救无效死亡。患者有明确的活禽市场接触史,咽拭子检测H7N9禽流感病毒核酸阳性。患者的密切接触者无继发病例。通过强化监测流感病例215例,均未发现H7N9禽流感病毒核酸阳性。患者暴露的活禽交易市场外环境20份标本检出3份H7N9禽流感病毒核酸阳性。结论以后仍有可能出现人感染H7N9禽流感病例,各项防控措施必须加强。     

河北省首例人感染H7N9禽流感疫情暴露危险因素探讨及对策

目的探讨河北省首例人感染H7N9禽流感病例的可能暴露危险因素及防控策略。方法描述流行病学研究方法。结果廊坊市共报告1例人感染H7N9禽流感确诊病例,安次区XX菜市场1处污水H7N9禽流感病毒核酸检测阳性,6名可疑暴露人员咽拭子标本H7N9禽流感病毒核酸检测阴性,175份禽类标本检测结果均为阴性。结论本次疫情的发生证实新型H7N9禽流感已在廊坊市家禽间存在并传播到人。在活禽宰杀市场,野鸟和家禽存在密切接触,受感染野禽排出的粪便会导致家禽的感染,可造成新型H7N9病毒的传播。在活禽市场环境接触禽类具有更高风险,前往活禽市场但无禽类接触同样具有危险。关闭市城区活禽宰杀市场,推行＂禽类定点屠宰、白条禽上市＂制度将大大降低疫情发生的风险。     

深圳市1例人感染 H7N9禽流感的流行病学调查

目的：通过对我市1例人感染 H7N9禽流感患者的流行病学调查,为人感染 H7N9禽流感的科学防控提供依据。方法：采用流行病学调查方法,调查病例的发病经过、可能的感染来源、传播途径及暴露因素等,对患者的密切接触者进行医学观察,同时对患者进行临床诊治、实验室检测。结果：确诊1例人感染 H7N9禽流感病毒,经救治后症状好转。患者无明确的活禽及市场暴露史,咽拭子检测 H7N9禽流感病毒核酸阳性。52名密切接触者中有1名出现呼吸道症状,经采样检测也均排除H7N9禽流感;其他密切接触者在观察期间均未出现发热、咳嗽、咽痛等呼吸道症状。通过扩大监测流感样病例（IL I ）1188例以及严重急性呼吸道感染病例（S A RI ）20例,均未发现人感染H7N9禽流感病例。结论：患者的感染来源不明,应加大宣传力度,减少人感染H7N9流感病毒的风险。     

乌鲁木齐市2017年2起人感染H7N9禽流感疫情分析

目的 对乌鲁木齐市2017年监测发现的2例人感染H7N9禽流感病例疫情进行调查分析,为人禽流感疫情防控提供有效参考依据。方法 对患者、密切接触者和活禽市场开展流行病学调查,采集病例呼吸道标本和外环境标本应用实时荧光定量PCR (real-time PCR)方法,检测甲型流感病毒及H7N9禽流感病毒特异的核酸片段,进行分析。结果 调查发现2例毫无关系患者同一天发热,先后检测出H7N9流感病毒核酸。2例患者均为男性,年龄相近,都有基础性疾病,经过救治,其中1例患者核酸检测转阴,症状消失救治成功。另1例患者核酸检测持续阳性,最终救治无效死亡。流行病学调查患者发病前7天均无活禽接触史,有相同的活禽宰杀点暴露史,经外环境采样,多份标本检测出禽流感病毒核酸。结论 2例感染H7N9禽流感病例感染来源于受H7N9病毒污染的活禽宰杀店的可能性较大,建议加强沿街商铺的规范管理和卫生消毒工作,规范禽类宰杀与销售。医疗机构加强流感样病例监测和不明原因肺炎监测是及时发现人禽流感病例的重要手段。     

广州市1起人感染H7N9禽流感家庭聚集性疫情调查分析

目的分析广州市首起人感染H7N9禽流感家庭聚集性疫情的流行病学特征,追溯感染来源,为预防控制人感染H7N9禽流感疫情提供科学依据。方法对病例、密切接触者和涉禽场所进行详细的流行病学调查,采集呼吸道标本和环境标本,采用RT-PCR方法检测H7N9病毒核酸。结果首例患者2014年1月3日发病,11日确诊为人感染H7N9禽流感病例,有活禽市场暴露史,病情危重;其密切接触者(女儿)14日发病,18日确诊为人感染H7N9禽流感病例,轻症病例,感染途径可能为活禽市场暴露或与患病父亲的密切接触。经积极处理和救治,疫情得到有效控制,两病例康复出院。结论此疫情为人感染H7N9禽流感家庭聚集性疫情,感染途径可能为活禽市场暴露和有限的人传人。及时开展流行病学调查和涉禽市场环境污染监测;加强病例及密切接触者管理、规范市场管理是控制人感染H7N9禽流感疫情的有效措施。     

深圳市龙岗区一例人感染H5N6禽流感病例调查分析

目的分析龙岗区1例人感染H5N6禽流感病例的流行病学特征,为人感染H5N6禽流感的防控提供参考依据。方法运用现场流行病学调查方法,对病例的发病情况、感染来源和途径及暴露危险因素等进行现场调查,并结合相关标本实验室检测结果进行分析。结果患者于2016年1月1日出现发热,体温39.5℃,有禽类密切接触史,采咽拭子H5N6禽流感病毒核酸检测阳性。患者无外出史和病例密切接触史。经抗病毒治疗20 d痊愈。密切接触者20名均未出现发热及相关呼吸道症状,采集其中16人份咽拭子H5N6病毒核酸检测均阴性。采集病家周围2家市场的7个活禽档口外环境标本35份,H5N6病毒核酸检测阳性11份,阳性率为31.43%;活禽从业人员标本6份,均为阴性;采集患者所在街道的18家活禽市场外环境标本90份,H5N6病毒核酸检测阳性29份,阳性率为32.22%,13个市场检出H5N6禽流感病毒,市场检出率为72.22%。结论患者感染原因为活禽市场暴露,属本地散发个案,未见人间传播,市场活禽摊档污染严重,应加强市场卫生管理。     

开封市首例人感染H7N9禽流感调查报告

目的确定人感染H7N9禽流感疫情,查明感染来源,以便采取相应措施控制疫情,为今后预防控制工作提供科学依据。方法对河南省开封市1例不明原因肺炎病例进行现场流行病学调查,同时采集患者咽拭子,采用荧光定量PCR方法进行流感病毒核酸检测,包括甲型、H1亚型、H3亚型、H5亚型、H7亚型和N9亚型。根据现场流行病学调查和实验室检测结果对该病例进行诊断和分析。结果该患者厨师职业,病初表现为流感样症状,并伴有胸闷,病情持续性加重,临床诊断为重症肺炎、急性呼吸窘迫综合征,不排除人感染H7N9禽流感病毒的可能。患者咽拭标本禽流感病毒(H7N9)核酸阳性。患者发病前未接触过类似病人,但接触过屠宰的禽类。所有密切接触者经医学观察8 d均未出现类似症状。结论该病例确诊为开封市首例人感染H7N9禽流感病例,未发现人传人的现象。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.     

Development Is A High Level Inheritance for China Time-honored Brand Products

<正>As culture is the soul of a nation,the three books,"History of Chinese Philosophy,""History of Chinese Culture"and"History of Chinese Science and Technology"have demonstrated the superiority of our great Chinese culture,and its significant impact in the field of international culture.Both core value and practical value of the Chinese culture are very clear,reflected in the views of universe,nature,life,health,disease,and therapy and related considerations,concepts,and technical methods.