先天性主动脉瓣下狭窄超声心动图6例分析

主动脉瓣下狭窄是一种罕见的先天性心脏病,是指左室流出道内的狭窄,可分为膜型主动脉瓣下狭窄、肌性主动脉瓣下狭窄和混合性主动脉瓣下狭窄.膜型主动脉瓣下狭窄又称孤立性主动脉瓣下狭窄:系由主动脉瓣瓣下水平的左室流出道内形成的纤维隔膜或纤维肌性组织所造成的狭窄.室间隔与左室后壁多呈对称性肥厚,它可以并发室间隔缺损、法乐氏四联症、肺动脉瓣狭窄及动脉导管未闭.若误诊可导致严重后果,故术前诊断颇为重要.超声心动图对本病诊断帮助很大,为此将我院接受超声检查诊为主动脉瓣下狭窄的6例患者进行分析.     

主动脉瓣置换术后左室流出道流速增加患者的防治策略

目的探讨主动脉瓣置换术后左室流出道流速增加的危害及防御治疗策略。方法选取62例单纯主动脉瓣膜置换术患者，术后复查超声检测左室流出道流速明显增加（〉2．5m/s）患者的发生率及与病种的关系。重度主动脉瓣狭窄患者保证合适充分容量负荷，降低心肌应激性（舒缓心肌），防治心律失常，低血压患者提高灌注压力的防御性治疗策略，分析患者的治疗效果。结果本组62例患者，左室流出道流速增加〉2．5m／s11例（17．5％），其中5例并发轻度SAM征象；12例重度单纯主动脉狭窄（AS，,中发生7例（58．3％）；36例AS合并单纯主动脉关闭不全（AI）中发生4例（11．1％）；本组AI患者中无一例发生流速增加。本组死亡1例，2例患者左室流出道梗阻诱发血压降低、心率增加危象，其余病例未发生典型，临床危象，顺利度过围术期。结论重度主动脉瓣狭窄患者术后左室流出道流速增高的发生率较高，左室流出道梗阻严重时如果不能及时明确诊断正确处理，会有致命性后果发生；积极采取有效的防御治疗措施，尽量避免心律失常的发生。     

瓣膜置换术治疗钙化性主动脉瓣狭窄29例的体会

目的 探讨钙化性主动脉瓣狭窄的手术治疗要点.方法 回顾性分析29例行主动脉瓣置换术治疗钙化性主动脉瓣狭窄患者的临床资料.结果 术后随访8个月,29例患者症状明显改善,心功能Ⅰ级23例,Ⅱ级4例,Ⅲ级2例;左室射血分数为52%～73%,人工瓣跨瓣压差为10～22 mmHg,室间隔及左室后壁厚度8～10 mm,重度低心排综...     

超声心动图评价PCI术前后非ST段抬高急性冠脉综合征左心室结构与心功能变化

目的应用超声心动图量化评价经皮冠状动脉介入(PCI)术前后非ST段抬高急性冠脉综合征(NSTEACS)患者左心室结构与心功能变化。方法选择经冠状动脉造影(CAG)证实存在冠状动脉狭窄或闭塞并接受PCI术的NSTEACS患者20例,比较术后与术前超声心动图反映左心室结构与收缩功能指标的变化:室间隔(IVS)与左室后壁(LVPW)厚度,左心室舒张末期内径(LVDd)和收缩末期内径(LVDs),左室射血分值(LVEF)和左室短轴缩短率(FS),左室舒张末期容量(LVVd)和收缩末期容量(LVVs)等。结果LVEF、FS术后与术前相比具有统计学意义(P<.01),其余各指标术后与术前相比差异均无统计学意义。结论20例患者PCI术后左室收缩功能显著提高;左心室结构无明显改变。     

应用心脏彩超评价经导管主动脉瓣植入术对老年主动脉瓣狭窄患者的影响

[目的]研究心脏彩超评价经导管主动脉瓣植入术(TAVI)对老年主动脉瓣狭窄患者的价值。[方法]选取我院2016年1月至2018年2月收治入院行TAVI的老年主动脉狭窄患者34例,分析患者基线资料和手术结果,比较术前与术后4周、术后12周心脏彩超各指标的结果。[结果]34例患者均顺利完成TAVI,无患者死亡;比较患者术前经胸超声心动图(TTE)、术中经食管超声心动图(TEE),主动脉瓣环内径、主动脉窦部内径、主动脉窦部高度、左室流出道内径和左室射血分数(LVEF)等指标测量值,差异无统计学意义(P>0.05);患者左室舒张末期内径在术前与术后4周、术后12周之间比较,差异无统计学意义(P>0.05),患者左室收缩末期内径、峰值跨瓣压差、平均跨瓣压差、LVEF和有效瓣口面积在术前与术后4周、术后12周之间比较,差异有统计学意义(P<0.05)。[结论]TAVI治疗老年严重主动脉瓣狭窄患者,疗效显著,在术前、术中和术后应用心脏彩超检查及随访具有重要意义。     

国人主动脉瓣狭窄主动脉根部解剖的研究

目的:随着经导管主动脉瓣置换术的发展,了解主动脉根部的解剖对于主动脉瓣瓣膜支架的选择和减少并发症是非常必要的?方法:34例主动脉瓣狭窄患者及39例正常对照行双源CT(Dual Source CT,DSCT)及经胸心脏超声(transthoracic echocardiography,TTE)检查,DSCT在斜冠状面及矢状面分别测量收缩末期及舒张末期主动脉根部各径线,瓣环直径和左室流出道直径?超声测量主动脉根部及左室流出道直径,并且和DSCT测量值对比?结果:主动脉瓣狭窄组左冠状动脉(left coronary ostia,LCO)高度?右冠状动脉(right coronary ostia,RCO)高度?冠状窦(sinus of Valsalva,SV)直径?左右冠状窦高度与对照组相比,差异无统计学意义;主动脉瓣狭窄组瓣环(aortic annulus,AA)直径?主动脉窦和升主动脉连接处(Sino-Tubular Junction,STJ)直径?升主动脉 (ascending aorta,AO) 直径?左室流出道 (left ventricular outer tract,LVOT) 直径?主动脉瓣和二尖瓣之间纤维结构(continuity fibrous,CF)距离,室间隔 (interventricular septum,IVS) 厚度明显比对照组大(P < 0.05)?主动脉瓣狭窄组及对照组收缩末期AA?SV?STJ?AO直径?IVS厚度明显比舒张末期大(P < 0.05),收缩末期LVOT直径明显比舒张末期小(P < 0.05)?主动脉瓣狭窄组及对照组AA及LVOT直径冠状面测量值均大于矢状面测量值?主动脉根部直径(AA?SV?STJ?AO)TTE测量值与DSCT测量值相比,相关性好(相关系数分别为r = 0.84,r = 0.87,r = 0.82,r = 0.82),差异均有统计学意义(P < O.05)?结论:主动脉瓣狭窄患者主动脉根部扩张?左室流出道变长扩张?室间隔变厚及冠状动脉变异较大,由于TTE的诊断作用有限,因此经导管主动脉瓣置换患者术前进行DSCT检查对于瓣膜支架的选择及减少并发症有重要意义?     

高血压病左房内径增大与左室结构改变的关系

目的 :探讨高血压病患者左房增大与左室结构改变的关系及临床意义。方法 :使用日本SSD 63 0超声心动图仪对 60例高血压病患者行超声心动图检查 ,测定左房内径 ,左室舒张末期内径 ,左室后壁厚度和室间隔厚度及左室重量。结果 :左房内径≥ 40mm组 ,左室扩大或肥厚的发生率显著高于 <40mm组 (P <0 .0 5 ) ;左房内径变化与左室内径及左室重量的变化呈显著相关 (P <0 .0 1)。结论 :高血压病患者随着左房内径增大常伴有左室结构改变的趋势 ,可能是高血压性心脏病的早期表现。     

肥厚型梗阻性心肌病2例

例 1　男 ,2 3岁。反复晕厥 3 + 年。超声心动图示室间隔非对称性增厚 ,左室后壁增厚 ,二者比例 2 .7。左心造影示左室肌肥厚 ,心腔狭窄 ,尤其主动脉瓣下明显。于 1988年 7月手术 ,术中见左室、右房增大 ,右室前壁心外膜有直径约 1cm增厚斑块 ,术前测左室平均压 9.6k Pa ( 72 mm Hg) ,主动脉平均压 10 .4k Pa( 78mm Hg)。常规建立体外循环 ,经主动脉根部切口探查见室间隔增厚 ,向左室腔凸出 ,主动脉瓣下左室流出道狭窄。直视下切除部分增厚室间隔 ,长约 2 cm ,宽约 1cm ,厚约 0 .5 cm。停机拔管后测左室压 5 .1k Pa( 3 8m m Hg) ,术后恢…     

超声心动图对PCI术后ST段抬高急性冠脉综合征左心室损害恢复程度的评价

目的应用超声心动图量化评价经皮冠状动脉介入(PCI)术后ST段抬高急性冠脉综合征(STEACS)患者左心室结构和收缩功能损害的恢复程度。方法选择经冠状动脉造影(CAG)证实存在冠状动脉狭窄或闭塞并接受PCI术的STEACS患者20例,比较术后与术前超声心动图指标及超声征象的变化,指标包括室间隔(IVS)与左室后壁(LVPW)厚度、左心室舒张末期内径(LVDd)和收缩末期内径(LVDs)、左室射血分值(LVEF)和左室短轴缩短率(FS)、左室舒张末期容量(LVVd)和收缩末期容量(LVVs);超声征象包括左室室壁瘤和附壁血栓等。结果(1)20例患者PCI术后与术前超声心动图指标相比:LVEF、FS术后明显提高(P<0.01);LVVd术后明显增大(P<0.05)。(2)术前梗死区延展4例(20%)、术后室壁瘤形成1例(5%);术前无左室附壁血栓,术后发生1例(5%)。结论PCI术后左室收缩功能明显提高,左室舒末容量增大,超声心动图为评价PCI术后STEACS患者左心室损害恢复程度提供了量化指标。     

超声心动图在主动脉瓣下狭窄诊断中的应用价值分析

目的：探讨超声心动图诊断主动脉狭窄的应用价值。方法：对本院2年内60例超声检查诊断的主动脉瓣下狭窄患者（观察组）进行回顾性诊断分析,并与60例健康查体者（对照组）进行对比,总结本病的超声诊断方法。结果：SAS组与对照组的左室舒张末内径（LVDd）比较差异无统计学意义（P〉0.05）。两组患者的室间隔及左室后壁的收缩期、舒张期厚度（Ts,Td）及增厚率（△T%）,左室舒张末内径（Dd）,左室流出道血流速（Vmax）及压差（PG max）比较差异均有统计学意义（P〈0.05）。结论：超声心动图在诊断SAS方面有极大的优势,为临床提供准确的参考依据。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.     

Development Is A High Level Inheritance for China Time-honored Brand Products

<正>As culture is the soul of a nation,the three books,"History of Chinese Philosophy,""History of Chinese Culture"and"History of Chinese Science and Technology"have demonstrated the superiority of our great Chinese culture,and its significant impact in the field of international culture.Both core value and practical value of the Chinese culture are very clear,reflected in the views of universe,nature,life,health,disease,and therapy and related considerations,concepts,and technical methods.