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1.
目的探讨腹股沟嵌顿疝肠坏死的发生时间。方法采用回顾性分析4年间收治的腹股沟嵌顿疝157例,其中23例肠坏死行肠切除术,对其发病特点及诊断治疗方法进行总结。结果腹股沟嵌顿疝超过8h后肠管坏死。结论应早期诊断并治疗腹股沟嵌顿疝,以降低肠管坏死切除率,减少并发症。  相似文献   

2.
目的 讨论婴幼儿腹股沟斜疝嵌顿后易并发肠管坏死、睾丸坏死等并发症的原因及疗效.方法 回顾性分析106例经手术治疗的婴幼儿嵌顿疝,分析发生并发症的主要原因.结果 106例患儿7例发生肠坏死,行肠切除、肠吻合术;4例回盲部嵌顿行阑尾切除术;5例女婴卵巢嵌顿行还纳术;4例睾丸坏死,予切除;术后均痊愈出院,随访6个月至2年,2例发生睾丸萎缩.结论 对有腹股沟包块,一经确诊或不能排除嵌顿疝者,应放宽手术指征,尽快手术探查,以减少并发症的发生.  相似文献   

3.
新生儿嵌顿性腹股沟斜疝45例临床分析   总被引:7,自引:0,他引:7  
目的总结新生儿嵌顿性腹股沟斜疝的诊治经验。方法回顾分析45例新生儿嵌顿性腹股沟斜疝的临床资料。结果非手术疗法15例,手术30例,其中肠坏死13例,睾丸坏死11例,卵巢坏死1例,均需手术切除。全部病例均治愈出院,无死亡病例。结论早期诊断反正确处理是治疗新生儿嵌顿性腹股沟斜疝的关键。  相似文献   

4.
新生儿嵌顿性腹股沟斜疝治疗   总被引:1,自引:0,他引:1  
郑练  陈伦家 《河北医学》2005,11(4):353-354
目的:探讨影响新生儿嵌顿疝治疗的因素。方法:对我院1995年至2003年收治的39例新生儿嵌顿疝进行回顾性研究。结果:手术治疗28例,肠管坏死12例,睾丸坏死8例,手法,复位11例,无死亡病例。结论:早期诊断和治疗及正确的围手术期处理是新生儿腹股沟嵌顿疝治疗的关键。  相似文献   

5.
目的探讨重度营养不良患儿腹股沟嵌顿疝并部分坏死回肠切除术后的护理。方法对16例重度营养不良腹股沟嵌顿疝患儿采取保暖、预防感染、营养支持、保持置管通畅、保护切口及皮肤、观察并发症、指导喂养等护理措施。结果16例均痊愈出院,无护理并发症。结论积极有效的护理方法是重度营养不良腹股沟嵌顿疝患儿术后康复的关键。  相似文献   

6.
目的:研究嵌顿疝患儿血浆中二胺氧化酶(diamine oxidase,DAO)及肠脂肪酸结合蛋白(intestinal fatty acid binding protein,I?FABP)在不同嵌顿时间段的变化情况及对预测嵌顿肠管血运情况的价值。方法:收集临床资料,分为嵌顿疝组和对照组,嵌顿疝组收集32例嵌顿疝患儿术前30 min血标本,其中非肠切组22例与肠切组10例,肠切组标本送病理诊断,另外对照组收集腹股沟斜疝患儿血标本10例。离心提取上层血清,采用酶联免疫吸附法测定样品血清中DAO和I?FABP的浓度。结果:嵌顿疝组与对照组相比,DAO、I?FABP水平明显提高(P < 0.05)。DAO、I?FABP水平随着嵌顿的进展有明显增高,呈正相关(P < 0.05)。肠切组患儿的DAO、I?FABP水平与非肠切除组相比,均有明显提高(P < 0.05)。DAO>27.10 U/mL时,诊断考虑肠管处于濒临坏死或坏死状况的灵敏度为70.0%,特异度为95.5%;I?FABP>1 654.50 ng/L时,诊断考虑肠管处于濒临坏死或坏死状况的灵敏度为90.0%,特异度为86.4%。结论:小儿嵌顿疝中,血浆中的DAO与I?FABP水平有着明显的时间依赖性,且能相对较敏感地反映实际肠管血运情况,特别对于早期了解嵌顿疝患儿肠管缺血情况有较大帮助,能为临床医师的治疗措施提供证据。  相似文献   

7.
郭德贵  李油山 《西部医学》2007,19(5):878-878
目的总结婴儿嵌顿性斜疝致器官坏死的原因,预防严重并发症的发生。方法对20例嵌顿性斜疝致器官坏死患儿的临床资料进行回顾性分析。结果6例大网膜坏死者予以切除;14例小肠坏死者行肠切除吻合术;8例合并睾丸坏死者行睾丸及精索切除。结论临床遇到不明因的哭闹、腹胀、呕吐、拒食的患儿应仔细全面查体,高度警惕腹股沟肿物的性质;及时细致地手术探查是避免漏误诊和预防脏器嵌顿坏死的重要措施。  相似文献   

8.
目的总结52例老年人腹股沟嵌顿疝的治疗经验。方法嵌顿疝松解还纳术,修补后壁,应用Bassini法20例;Halsted法29例;有腹膜炎体征,经腹手术缝合内环口,未行修补术3例。对手术方法、并发症、死亡原因进行了分析。结果肠管坏死8例,切口感染3例。治愈46例,死亡6例。结论老年人腹股沟疝应尽早择期手术,出现嵌顿后并发症多,病死率高。  相似文献   

9.
目的:讨论阴茎环状异物嵌顿致阴茎绞窄的病因、分级、诊断、治疗及预后.方法:对1例所收治阴茎环状异物嵌顿致阴茎绞窄及复习文献资料所报道病例进行病因、分级、诊治的综合分析.结果:阴茎环状异物嵌顿致阴茎绞窄易于诊断,及时根据特定嵌顿物采用特定的方法解除嵌顿是主要治疗手段.结论:阴茎环状异物嵌顿敛阴茎绞窄可引起严重并发症,及时有效解除嵌顿可有效避免并发症的发生.  相似文献   

10.
目的 提高对宫内节育器并发症的诊断。方法 回顾性分析1例宫内节育器嵌顿合并肠坏死的临床资料。结果 急诊体检发现,盆腔内有边界不清的肿块,后穹隆穿刺抽得3ml血性液体,剖腹探查发现,子宫后壁有节育环嵌顿,部分肠段坏死,遂行次全子宫切除,回肠部分切除,术后8d出院。结论 放置金属单环IUD后应行B超随访。及时发现问题,避免严重并发症发生。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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