虫类中药溻渍结合生肌玉红膏涂药治疗糖尿病足溃疡疗效观察

目的观察虫类中药溻渍结合生肌玉红膏涂药治疗糖尿病足溃疡的临床疗效。方法将40例糖尿病足溃疡患者随机分为对照组和治疗组,每组20例。对照组采用常规治疗和护理方法,治疗组在对照组基础上加用虫类中药溻渍和生肌玉红膏涂药,每日1次,两组均以1个月为1个疗程,2个疗程后,根据观察记录的健康肉芽首次出现时间(GT)和溃疡面愈合时间(HT)对疗效进行判定和记录。结果治疗组治疗后总有效率为90%,对照组为65%,治疗组疗效优于对照组,两组比较差异具有统计学意义(P0.05)。两组患者治疗后不同程度的GT、HT比较,差异有统计学意义(P0.05)。结论虫类中药溻渍结合生肌玉红膏涂药治疗糖尿病足溃疡疗效明显,充分体现了中医药"简、便、验、廉"的特点,值得临床推广。     

中医祛腐生肌法换药促进肛周脓肿患者创面愈合的临床观察

目的：观察中医祛腐生肌法换药促进肛周脓肿患者术后疮面愈合的临床效果。方法：选取2015年2月～2016年6月在我院行手术治疗的肛周脓肿患者56例,将其随机分为观察组和对照组,每组各28例,观察组采用中医祛腐生肌法换药,对照组采用生肌玉红膏纱条换药,观察对比两组患者的临床疗效及创面分泌物评分、创缘水肿情况评分。结果：观察组总有效率为96．4％,明显高于对照组,P＜0．05,差异具有统计学意义;观察组患者治疗后的创面分泌物评分和创缘水肿情况评分均明显低于对照组,P＜0．05,差异具有统计学意义。结论：肛周脓肿术后采用中医祛腐生肌法换药可有效促进创面愈合,缩短愈合时间,减轻患者痛苦,具有良好的疗效。     

中医祛腐生肌法促进肛周脓肿及肛瘘术后创面愈合的临床研究

目的分析和探讨中医祛腐生肌法促进肛周脓肿及肛瘘术后创面愈合的临床效果情况。方法选取本院肛肠外科所收治的肛周脓肿及肛瘘手术后的患者共计74例作为本次调查研究的对象,秉承随机双盲原则,将本次调查研究的74例患者随机分为观察组和对照组,每组各37例。为观察组患者采用祛腐生肌治疗,初期应用生肌红粉膏换药,创面红活而腐肉脱落后进行生肌玉红膏治疗。对照组采用单独生肌玉红膏治疗,在治疗28天后,观察两组患者治疗有效率等方面情况,分析不同治疗方法下的疗效差异。结果经过结果对比和分析可以显著发现,观察组患者临床治疗总有效率等方面情况显著优于对照组,其差异较为明显,具备统计学意义(P0.05)。结论通过临床数据分析可以显著发现,为肛周脓肿及肛瘘术后患者采用中医祛腐生肌法来进行治疗,可以较好地促进患者创面愈合,临床治疗有效性相对单独使用生肌玉红膏的患者来说有显著提高,值得进行临床实际应用。     

溃疡油治疗糖尿病足溃疡临床疗效观察

目的观察溃疡油治疗糖尿病足溃疡的临床疗效。方法将50例湿热蕴结型糖尿病足溃疡患者随机分为治疗组28例、对照组22例,2组除相同的基础治疗外,治疗组使用溃疡油外敷,对照组使用祛腐生肌膏外敷,2组均以28d为1个疗程。对2组溃疡面愈合情况疗效及治疗后溃疡面积分进行比较。结果溃疡面愈合情况疗效治疗组28例中治愈12例(42.86%),显效10例(35.71%),有效4例(14.29%),无效2例(7.14%),总有效率为92.86%;对照组22例中治愈5例(22.73%),显效5例(22.73%),有效4例(18.18%),无效8例(36.36%),总有效率为63.64%。治疗组临床疗效优于对照组(P<0.05)。治疗后溃疡面积分中创周浸润带积分2组比较差异无统计学意义(P>0.05);治疗组肉芽生长时间积分、创周肿胀积分、脓液渗出积分、创面缩小率积分及疼痛积分较对照组明显减少,2组比较差异有统计学意义(P<0.05)。结论溃疡油外用治疗糖尿病足溃疡具有良好的临床疗效。     

祛腐生肌膏治疗低位肛瘘的临床观察

目的为探讨祛腐生肌膏用于肛瘘术后促进创面愈合的疗效.方法将60例肛瘘手术患者分为治疗组和对照组各30例,治疗组除采用与对照组相同的治疗外,加用祛腐生肌膏.结果治疗组在减轻创面疼痛、渗出及创面愈合时间方面均明显优于对照组(P＜0.01).结论祛腐生肌膏可明显缩短创面愈合时间,解除组织炎症水肿,缓解疼痛渗出,具有临床应用价值.     

祛腐生肌膏促进感染创面愈合作用的实验研究

目的观察祛腐生肌膏对感染创面的作用,为中医古方和临床用药提供科学依据。方法采用新西兰大白兔12只,制作感染创面动物模型,形成36个创面,随机分为实验组、药物对照组和空白对照组,每组12个创面。实验组用祛腐生肌膏,药物对照组用红霉素软膏,空白对照组用生理盐水进行换药治疗,分别于伤后7天在创面肉芽组织取材,测定肉芽组织蛋白质含量,计数成纤维细胞、毛细血管,检查脓液中吞噬细胞数,记录创面愈合率、愈合时间。结果祛腐生肌膏可以促进创面成纤维细胞及毛细血管的增殖（P〈0.01）;增加创面蛋白质含量（P〈0.01）,促进肉芽组织生长,提高创面愈合率（P〈0.01）,缩短创面愈合时间（P〈0.01）。结论祛腐生肌膏具有促进感染创面愈合的作用,其机制包括促进组织修复细胞和炎性细胞的增殖,促进肉芽组织生长。     

祛腐生肌膏治疗低位肛瘘的临床观察

目的:为探讨祛腐生肌膏用于肛瘘术后促进创面愈合的疗效。方法:将60例肛瘘手术患者分为治疗组和对照组各30例,治疗组除采用与对照组相同的治疗外,加用祛腐生肌膏。结果:治疗组在减轻创面疼痛、渗出及创面愈合时间方面均明显优于对照组(P<0.01)。结论:祛腐生肌膏可明显缩短创面愈合时间,解除组织炎症水肿,缓解疼痛渗出,具有临床应用价值。     

祛腐生肌膏促进创伤感染创面愈合作用的临床观察

摘要:目的:探讨祛腐生肌膏促进创伤感染创面愈合的作用。方法:依据创伤感染标准入选60例门诊和住院创伤感染的患者,随机分为治疗组和对照组。分别动态观察创面色泽、愈合时间、新生上皮组织、肉芽组织、吞噬细胞数、创面周缘炎症带面积等变化。结果:2组创面色泽、愈合时间、新生上皮组织、肉芽组织、吞噬细胞数、创面周缘炎症带面积及临床疗效比较有明显差异(P<0.05～0.01)。结论:祛腐生肌膏有较好的促进创伤感染创面愈合作用。      

活络祛寒汤加味内服结合生肌愈溃膏外用治疗糖尿病足溃疡体会

目的:探讨活络祛寒汤加味内服结合生肌愈溃膏外用治疗糖尿病足溃疡的效果。方法:选择2010年6月~2016年6月我院内分泌科接诊的30例糖尿病足溃疡患者,均给予活络祛寒汤加味内服结合生肌愈溃膏外用治疗,观察治疗效果。结果:全部病例经过三个疗程的治疗,治愈20例,显效5例,有效4例,无效1例,总有效率96.6%。结论:活络祛寒汤加味内服结合生肌愈溃膏外用治疗糖尿病足溃疡创面的愈合具有很好的效果。     

自制祛腐生肌膏联合吹氧法治疗压疮效果观察

目的探讨重度（Ⅲ～Ⅳ期）压疮的治疗方法。方法选择60例Ⅲ～Ⅳ期压疮患者随机分为观察组和对照组各30例,对照组采用常规方法及雷佛奴尔液湿敷创面;观察组采用常规方法加上自制祛腐生肌膏联合吹氧法治疗创面。结果观察组的疗效及愈合时间均显著优于对照组（P〈0.05）。结论在常规护理基础上采用自制祛腐生肌膏联合吹氧法治疗创面可以显著提高Ⅲ～Ⅳ期压疮疗效。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.