孔源性视网膜脱离环扎加压术后视力和屈光改变等临床研究

为评价孔源性视网膜脱离成功地不扎加压手术后视力，眼屈光状态，前房深度，晶体厚度和眼轴长度的改变，用ＴｏｐｃｏｎＲＭ－Ａ２３００屈光计测量眼屈折力，Ｔｏｐｃｏｎ－ＯＭ－４角膜曲率计测量角膜屈折力，前房深度，晶体厚度和眼轴长度用ＤＧＨ／Ｊｅｄｍｅｎ４０００型Ａ超定，随访６个月，５２例ＲＲＤ依环扎程度分为Ａ组２８眼和Ｂ组２４眼。结果在手术后近视有明显增加，眼轴长度增加，前房深度减少，而晶体厚度无明显改变     

PRK近视患者角膜屈光力、眼轴和角膜中央厚度的相关分析

目的 :通过测量近视眼的角膜屈光力、眼轴和角膜中央厚度 ,分析角膜屈光力、眼轴和角膜中央厚度与近视程度的关系。方法 :在进行PRK治疗的患者中 ,根据屈光度将 2 78例 (538只眼 )患者分成低、中、高和超高度四组 ,应用角膜地形图仪测定角膜屈光力 ,A型超声波测定眼轴及角膜中央厚度 ,数据用Exce 197软件计算处理。结果 :垂直径角膜屈光力 (4 4 0 1± 1 54D)明显大于水平径角膜屈光力 (4 3 10± 1 4 0D) ,P <0 .0 1。 (角膜总屈光力与屈光度的大小无关 ) ;角膜中央厚度与屈光度的大小无关 ,各屈光度组间差异无显著性。眼轴随屈光度的增大而延长 ,差异非常显著。结论 :在近视眼中 ,眼轴起着决定性的作用 ,度数越高 ,眼轴越长 ,而角膜屈光力不起作用或作用甚微。角膜中央厚度与近视程度无关。     

近视眼屈光系统超声测定值临床分析

作者采用日产NIDEKUS－2000型超声生物测量仪对近视眼患者661例（322眼）进行角膜中央厚度，眼轴长度，前房深度，晶体厚度，玻璃体腔纵径测量。结果：角膜中央厚度与屈光度、性虽、眼别无关；随着屈光度增高，眼轴长度明显延长，前房深度逐渐变浅，晶体厚度稍变厚，主要是玻璃体纵径明显延长。结果提示：眼轴延长是轴性近视的主要原因。同时强调了角膜中央厚度的精确测量及测定值的分析对近视眼屈光手术有重要的临床意义。     

近视眼屈光系统超声测定值临床分析

本文采用日产ＮＩＤＥＫＵＳ－２０００型超声生物测量仪对近视眼患者６６１例进行角膜中央厚度，眼轴长度，前房深度、晶体厚度、玻璃体腔纵径测量。结果：角膜中央厚度与屈光度、性虽、眼别无关；随着屈光度增高，眼轴长度明显延长，前房深度逐渐变浅，晶体厚度稍变厚，主要是玻璃体纵径明显延长，眼轴延长是轴性近视的主要原因，同时强调了角膜中厚度的精确测量及测定值的分析对近视眼屈光手术有重要的临床意义。     

近视眼角膜中央厚度,角膜中央屈光力,眼轴关系分析

探讨角膜中央厚度、角膜中央屈光力、眼轴与近视程度的关系。利用Ａ超、角膜地形图仪测定６８８只近视眼的上述参数,分低度、中度、高度、超刘度近视４组进行统计分析。结果显示随近视程度增高,眼轴相应延长,两者呈高度正相关;角膜中央屈光力相对保持稳定;角膜有变薄趋势,但变化幅度很小。眼轴测定有助于近视程度与近视手术疗效的评估。     

不同屈光度对角膜塑形镜控制近视进展的影响

目的 探讨不同近视屈光度对夜戴型角膜塑形镜(orthokeratology,OK镜)控制近视进展疗效的影响.方法 回顾性分析2016年1月至2019年12月于四川大学华西第四医院眼科行角膜塑形镜治疗的青少年儿童29例(58眼)的临床资料,按照等效球镜度数分为低度近视组(n=14,28眼)(等效球镜度≤3.00 D)和中度近视组(n=15,30眼)(3.00 D<等效球镜度≤6.00 D),记录两组戴镜前的裸眼视力、眼轴长度、平均角膜屈光度(AveK)、角膜厚度、角膜内皮,戴镜1年后的裸眼视力及眼轴长度,比较两组戴镜1年后裸眼视力的变化及眼轴的增长值.结果 戴镜1年后,两组裸眼视力均显著高于戴镜前,差异有统计学意义(P<0.05);戴镜1年后,中度近视组眼轴的增长值低于低度近视组,差异有统计学意义(P<0.05).结论 角膜塑形镜能显著提升患儿的裸眼视力,其控制眼轴增长的疗效在近视度数较高者中效果较好.     

夜戴型角膜塑形镜矫治青少年近视的临床观察

目的观察青少年近视患者配戴夜戴型角膜塑形镜对角膜曲率、角膜厚度和眼轴长度影响。方法随访满1年且资料完整的患者56例（112眼）,年龄9～15岁,男性22例,女性34例,近视度数均〈-6.00D。患者夜戴Boston XO角膜塑形镜,采用博士伦公司的ORBSCANⅡZ角膜地形图检查角膜厚度和角膜曲率,采用蔡司公司的IOL Master（光学生物测量仪）测量眼轴长度。结果与戴镜前相比,戴镜3～12个月后,角膜地形图显示角膜曲率均明显变平,差异有统计学意义（P〈0.01）;角膜厚度有所变化,但差异无统计学意义（P=0.5992）;戴镜12个月后,眼轴长度有所增加,但差异无统计学意义（P=0.389 7）。结论夜戴型角膜塑形镜矫治青少年近视效果确切、安全。     

夜戴型角膜塑形镜矫治青少年近视的临床观察研究

目的 观察青少年近视患者配戴夜戴型角膜塑形镜(Ortho-KCL)后裸眼视力、角膜曲率、角膜厚度、眼轴长度的变化.方法 应用欧普康视科技股份有限公司提供的梦戴维夜戴型角膜塑形镜,对2010年6月至2012年6月于第二军医大学长征医院门诊就诊并随访的近视度数＜-6.00 D的50例患者(100眼)进行矫治.采用综合验光仪检测患者配戴前和配戴3、6、12、24个月后的裸眼视力,角膜地形图检测角膜曲率和角膜厚度,眼科A/B超测量眼轴长度.结果 患者配戴夜戴型角膜塑形镜3、6、12、24个月后裸眼视力较戴镜前均稳定提高;角膜曲率平均K值均减小(P均＜0.01).左右眼配戴夜戴型角膜塑形镜3、6、12、24个月后角膜厚度与戴镜前相比均无明显改变(P均＞0.05);眼轴长度略增加,但与戴镜前比较差异均无统计学意义(P均＞0.05).结论 配戴夜戴型角膜塑型镜能够有效提高近视青少年的裸眼视力,有效、安全地减缓近视发展.     

先天性近视儿童的屈光参数变化规律及与近视度数的相关性探讨

目的:探讨先天性近视中屈光参数的变化规律及其与近视度数之间的相关性。方法:对2013年2月至2016年2月在我院眼科选取近视儿童86例172只眼,参照儿童近视度数SE指数大小,将其分低度、中度、高度、超高度近视组四个组,测量所有患者的前房深度(ACD)、晶体厚度(LT)和眼轴长度(AL)、角膜前表面曲率(AC),总结分析近视度数与各参数之间的相关性。结果:对比分析检测结果发现:AL与SE、ACD呈正相关,而与LT、AC呈负相关关系;近视度数与LT/AL,ACD+LT/AL呈负相关,与AL/CR则呈正相关。结论:先天性近视儿童其眼球发育早于常人,眼轴变长,近视度数的增加主要是由于眼轴长度的增长。不同度数的患者其AC和AL差异显著,AC、LT与AL的比值变化趋势也不一致。     

近视眼前房深度、晶体厚度及眼轴长度分析

应用ＤＧＨ－４０００型眼部Ａ型超声测量仪检测了７２例近视眼及１８例正常对照眼的前房深度、晶体厚度及眼轴长度。结果表明：晶体厚度与前房深度二项平均值近视祖均大于对照组，晶体厚度在轻、中度与高度近视相比及眼轴长度在轻、中、高度近视各组间，差异均有高度显著性。由此，对近视眼的发病机理进行了回顾和讨论。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…