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1.
目的:介绍两种入路显露鞍区不同部位及不同类型肿瘤48例显微外科手术治疗经验。方法:经额颞联合耳前颞下入路露,经翼点入路晕露,显微外科手术切除颅中窝底鞍旁肿瘤,显微外科手术切除鞍内及鞍上肿瘤。手术入路根据肿瘤具体位置而定,颅中窝底鞍旁多采用经额颞联合耳前颞下入路^[1],鞍内及鞍上肿瘤则经翼点入路。结果:全切除47例,1例脊索瘤向海绵窦颅底生长行次全切除。结论:经额颞联合耳前颞下入路显露及翼点入路,鞍区肿瘤显露良好,采用显微手术治疗,是提高全切除率、降低死亡率的重要手段。  相似文献   

2.
垂体瘤、颅咽管瘤是鞍区最常见的肿瘤,其它还有鞍结节脑膜瘤、视神经胶质瘤和下丘脑胶质瘤等,翼点人路因其路径短、视角大,视为手术治疗鞍区肿瘤的经典入路。我们回顾性分析17例鞍区肿瘤的临床资料,探讨经翼点入路鞍区肿瘤的显微外科手术治疗方法。  相似文献   

3.
曾白云  胡滨 《广东医学》1997,18(7):439-440
利用MR检查结果指导63例鞍区肿瘤手术的入路选择,对MR检查示蝶窦气化良好,位于鞍内或轻度向鞍上发展的肿瘤,特别是肿瘤破坏鞍底、突向蝶窦者用经蝶手术入路;对蝶窦气化不良,肿瘤巨大、突破鞍隔向鞍旁发展,甚至呈蔓状生长者应用开颅入路;而对两者兼备者可应用上述两种联合入路。本组手术疗效良好,故MR对鞍区肿瘤的手术入路选择是有重要作用的。  相似文献   

4.
显微神经外科技术及翼点入路在鞍区肿瘤手术的应用   总被引:1,自引:0,他引:1  
目的:总结98例鞍区肿瘤患者经翼点入路显微手术治疗及翼点入路应用体会。方法:按照翼点入路各项操作步骤行鞍区肿瘤切除98例,介绍了操作方法并讨论显微神经外科技术在鞍区肿瘤手术中的应用,及不同部位肿瘤作相应手术操作调整的方法。结果:鞍区肿瘤应用翼点入路进行显微手术操作可良好显露鞍区及肿瘤各显微解剖结构以及手术操作平台,使其肿瘤全切率及患者预后得到明显提高。结论:显微神经外科技术及翼点入路手术操作的掌握和熟练程度的提高是显微神经外科技术的关键及获得良好手术效果的基础。  相似文献   

5.
鞍区肿瘤术后常见并发症循证护理的研究进展   总被引:2,自引:2,他引:0  
靳玉萍 《安徽医学》2010,31(7):847-849
鞍区肿瘤是颅内最常见的肿瘤之一。目前鞍区肿瘤手术入路基本有开颅肿瘤切除术,经鼻蝶入路肿瘤摘除术及经眉弓锁孔入路。鞍区肿瘤术后并发症较多,开展术后并发症的循证护理可以提高护理质量,利于患者的早日康复。本文综述了近几年来循证护理模式在鞍区肿瘤术后并发症的应用,以期指导临床实践。  相似文献   

6.
目的探讨眶上额外侧锁孔入路切除前颅窝底和鞍区肿瘤的临床效果。方法对30例采用眶上额外侧锁孔入路和30例传统经额下入路治疗的前颅窝底和鞍区肿瘤病例进行前瞻性对照研究。结果眶上额外侧锁孔入路与传统额下入路相比,肿瘤切除程度、主要术后并发症和术后复发率无显著性差异。但是锁孔入路手术创伤小.术中出血少,术后平均住院日缩短。结论眶上额外侧锁孔入路治疗前颅窝底和鞍区肿瘤创伤小且疗效满意。  相似文献   

7.
经颅微创手术治疗鞍区肿瘤   总被引:1,自引:0,他引:1  
乔鹏  戴刚 《中原医刊》2007,34(24):63-64
目的探讨鞍区肿瘤的经颅微创手术治疗方法。方法12例鞍区肿瘤应用开颅经眉眶上锁孔入路切除。结果12例视力均有恢复,随访2个月,无并发症。结论经眉眶上锁孔入路是切除鞍区肿瘤的理想手术方式。  相似文献   

8.
目的:总结经颅显微外科切除鞍区肿瘤的经验,探讨经颅切除鞍区肿瘤手术入路的选择。方法:回顾分析南通大学附属医院神经外科自2012年5月-2014年3月手术的鞍区肿瘤80例(脑膜瘤56例、垂体瘤12例、颅咽管瘤9例、皮样囊肿2例、神经内分泌源恶性肿瘤1例)的临床资料;手术入路包括翼点入路、额下入路和额外侧入路,肿瘤采用显微外科技术切除。分析全切除率、手术效果和并发症发生的情况。结果:采用翼点入路者50例,全切除率为66.0%;采用额下入路者16例,全切除率为75.0%;采用额外侧入路者14例,全切除率为71.4%。结论:显微手术是治疗鞍区肿瘤的主要手段,选择手术入路时应根据肿瘤的大小、生长方式以及肿瘤和周围重要结构的关系,遵循最优化和个体化原则,结合手术者的经验来决定。  相似文献   

9.
目的:探讨鞍区不同部位手术入路的选择。方法:介绍几种常用的鞍区手术入路。结果:眶颧额颞下入路对鞍旁肿瘤、翼点入路对蝶骨嵴肿瘤或海绵窦肿瘤、枕下入路对鞍背或脚间窝肿瘤可取得明显的手术显露。结论:根据鞍区不同部位而采取相应的手术入路对提高手术的全切率、降低致残率很有价值。  相似文献   

10.
鞍区肿瘤手术入路临床分析   总被引:2,自引:0,他引:2  
目的:对鞍区肿瘤手术切除的入路进行评价.讨论额下、翼点、经蝶、纵裂等手术入路的缺点.方法:鞍区肿瘤103例,经额下入路42例;经翼点入路22例;经纵裂入路11例;经蝶入路23例;胼胝体入路3例;经侧脑室入路2例.结果:本组病例肿瘤全部切除76例,全切除率73.79%.结论:正确的手术入路选择对于肿瘤切除有着决定作用,全切肿瘤以适当的并发症为代价是值得的.视神经减压效果以及手术创伤,经蝶以及内窥镜垂体瘤切除手术十分具有优势.在鞍区巨大肿瘤操作中,切除彻底与否,下丘脑以及垂体的保护,翼点入路具备优势.在侵入三脑室内的鞍区肿瘤,纵裂入路给我们提供可开阔的操作术野.  相似文献   

11.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

12.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

13.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

14.
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…  相似文献   

15.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

16.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

17.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

18.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

19.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

20.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

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