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1.
目的:探讨胸骨后甲状腺肿的外科治疗方法.方法:回顾性分析1999年1月~2006年10月我院收治的17例胸骨后甲状腺肿患者临床资料.结果:17例患者均行手术切除胸骨后甲状腺肿物,15例(88.2%)经颈部低位领式切口,2例(11.8%)经颈部低位领式切口加胸骨劈开.病理证实为结节性甲状腺肿13例(76.5%),滤泡性腺瘤3例(17.6%),甲状腺滤泡状腺癌1例(5.9%).术后出现喉返神经损伤表现1例(5.9%),无其他严重并发症和手术死亡病例.结论:CT检查有助于胸骨后甲状腺肿的诊断和术前评估.经颈部低位领式切口入路手术切除胸骨后甲状腺肿适用于大部分病例,手术创伤较小,安全可靠.  相似文献   

2.
目的:探讨胸骨后甲状腺肿的临床特点、诊断与外科治疗.方法:回顾分析经术后病理证实为胸骨后甲状腺肿14例的临床资料.结果:14例胸骨后甲状腺肿均为坠入性,良性病变12例,甲状腺癌2例,9例颈部低位领式切口;5例颈部低位领式切口辅以正中切口,其中2例仅胸骨上段劈开;3例胸骨全劈开.喉返神经损伤1例.结论:胸骨后甲状腺肿一经确诊,均应手术治疗,只要正确选择手术入路,术中仔细操作,都可避免严重手术并发症,取得良好的治疗效果.  相似文献   

3.
目的探讨胸骨后甲状腺肿的手术治疗方法及入路。方法回顾性分析28例胸骨后甲状腺肿的临床资料,25例行颈部低位领式切口,3例行颈部领式切口+胸骨劈开入路。结果28例患者接受手术治疗均获得成功,术后病理示结节性甲状腺肿22例,甲状腺腺瘤6例。术后并发症发生率11%(3/28),无死亡。随访3年以上,未见复发与癌变。结论颈部低位领式切口切除胸骨后甲状腺肿损伤小,容易操作,安全可靠。  相似文献   

4.
胸骨后甲状腺肿的外科治疗   总被引:1,自引:0,他引:1  
目的探讨胸骨后甲状腺肿的外科治疗方法。方法回顾性分析1990年1月-2007年10月收治的34例胸骨后甲状腺肿患者临床资料。结果 34例患者中30例(88.2%)经颈部低位领式切口,4例(11.8%)经颈部低位领式切口加胸骨劈开。病理证实为结节性甲状腺肿27例(79.4%),甲状腺腺瘤7例(20.6%),术后出现喉返神经损伤表现2例(5.9%),无手术死亡病例。结论 CT检查有助于胸骨后甲状腺肿的诊断和术前评估。经颈部低位领式切口入路手术切除胸骨后甲状腺肿适用于大部分病例,手术创伤较小,安全可靠。  相似文献   

5.
目的 探讨胸骨后甲状腺肿物的诊断、外科治疗的手术路径.方法 回顾性分析1998~2008年手术治疗胸骨后甲状腺肿患者23例的临床资料,19例采用颈部低领式切口,4例采用颈部低领式切口并胸骨正中劈开.结果 23例患者手术治疗均获得成功,其中结节性甲状腺肿16例,甲状腺腺瘤5例,甲状腺乳头状癌2例;术后并发症发生率13% (3 /23),无1例死亡.结论 颈部低位领式切口入路是切除胸骨后甲状腺良性肿瘤的理想入路方式,具有操作简单、损伤小、并发症少等优点;恶性肿瘤手术径路有待进一步探讨.  相似文献   

6.
目的:探讨胸骨后甲状腺肿物的诊断及手术方法。方法:回顾分析11年间手术治疗的胸骨后甲状腺肿物26例临床资料。结果:26例胸骨后甲状腺肿物患者接受外科治疗,均获成功。颈部低位领式切口入路切除23例(88.5%),颈部低位领式切口 胸骨正中劈开入路3例(11.5%)。术后并发症5例(19.2%),其中喉返神经损伤3例。结论:胸内甲状腺肿物的诊断主要根据症状、体征、胸片以及CT。一旦诊断为胸骨后甲状腺肿物,应手术治疗。大多选择颈部低位领式切口入路,具有容易操作、损伤小、并发症少等优点。  相似文献   

7.
目的:探讨胸骨后甲状腺肿的诊断及外科治疗方法。方法:回顾性分析2002年1月~2009年4月我院收治的16例胸骨后甲状腺肿患者临床资料。结果:16例患者均行手术切除胸骨后甲状腺肿物,11例(68.8%)经颈部低位领式切口,3例(18.8%)单纯纵劈胸骨,2例(12.4%)经颈部低位领式切口加胸骨劈开,病理证实为结节性甲状腺肿11例(68.8%),滤泡性腺瘤5例(31.2%),其中有2例局部微小癌形成。术后并发迟发的胸骨后血肿1例。无其他严重并发症和手术死亡病例。结论:CT检查有助于胸骨后甲状腺肿的诊断和术前评估。经颈部低位领式切口入路手术切除胸骨后甲状腺肿适用于大部分病例,手术创伤较小,安全可靠。  相似文献   

8.
邓淼  陈登庭 《中原医刊》2009,(20):15-17
目的探讨胸骨后甲状腺肿的诊断、手术及并发症的预防和处理。方法回顾性分析经外科手术病理证实的22例胸骨后甲状腺肿患者的临床资料。结果22例中结节性甲状腺肿10例,甲状腺腺瘤7例,结节性甲状腺肿癌变3例,甲状腺乳头状癌伴气管旁淋巴结转移1例,甲状腺滤泡状腺癌伴气管旁淋巴结和纵隔淋巴结转移1例。20例颈部低位领式切口入路切除,2例颈部低位领式切口并胸骨正中劈开入路。术后并发症发生率为22.7%。22例胸骨后甲状腺肿物患者术后1~5年随访无复发。结论胸骨后甲状腺肿术前行CT和MRI有助手术入路的选择;颈部低位领状切口手术对大多数胸骨后甲状腺肿是一种安全可靠并可行的选择。  相似文献   

9.
梁晓敏  肖丽颜  肖翠群  区爱武 《广东医学》2002,23(11):1201-1201
胸骨后甲状腺肿物与纵隔关系密切 ,主动脉、头臂静脉、作用头臂静脉、迷走神经等重要血管神经分布在纵隔 ,给胸骨后甲状腺肿物的外科治疗造成较大的困难。我院头颈科自 1985年 8月至2 0 0 0年 8月对 2 7例胸骨后甲状腺肿物进行手术切除。其中 ,颈部低位领式切口入路胸骨后甲状腺肿物切除 2 3例 ;颈部领式切口的胸骨劈开入路 3例 ;开胸加颈部领式切口 1例 ;手术均获成功。现将有关手术配合情况报告如下。1 临床资料1985年 8月至 2 0 0 0年 8月头颈科共收治胸骨后甲状腺肿物患者 2 7例。女2 0例 ,男 7例 ;年龄 2 5~ 82岁 ,中位年龄5 3岁。发…  相似文献   

10.
目的:探讨胸骨后甲状腺肿手术治疗经验.方法:回顾性分析31例胸骨后甲状腺肿手术患者临床资料,其中27例胸骨后甲状腺患者选择颈部低领式手术入路,4例患者行颈部低领式切口+胸骨劈开入路.结果:所有31例患者均顺利完成手术,全部完全切除肿块,无术后出血,无手术及住院死亡;术后随访0.5~4年,31例患者均未见复发.结论:胸骨后甲状腺肿多为良性病变,CT是其术前重要的诊断手段.手术切除肿块是胸骨后甲状腺肿有效治疗手段,首选颈部手术入路,必要时可联合胸骨劈开入路.  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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