三(3-乙炔基苯胺)-苯基硅烷改性含硅芳炔树脂的性能

以苯基三氯硅烷、3-氨基苯乙炔为原料,通过胺解反应合成了三（3-乙炔基苯胺）苯基硅烷（SZTA）,并通过傅里叶变换红外光谱（FT-IR）和核磁共振氢谱（¹H-NMR）表征了其结构。随后通过熔融共混的方法制备了不同配比的改性含硅芳炔树脂（PSA/SZTA）,借助黏度计、流变仪、差示扫描量热仪（DSC）、电子万能试验机、热重分析仪（TG）等考察了改性树脂的工艺性能、固化特性、弯曲性能、热稳定性能和热解动力学等。结果显示,引入SZTA后,改性PSA树脂的黏度降低62%;改性PSA树脂固化物的弯曲强度最高达到34.6 MPa,比未改性的PSA树脂提高了约54%;且改性树脂固化物在N₂中的5%热失重温度（T_d5）均高于500 ℃,保持了良好的耐热性能;PSA/SZTA-20固化物的热解表观活化能（E_a）的平均值为249 kJ/mol。     

PLLA-PDLA共混熔体的流变性能

将两种不同构型的聚L-乳酸（PLLA）与聚D-乳酸（PDLA）共混、熔融、挤出、压制成圆形薄片,利用高级旋转流变仪测试其流变性能。结果表明,聚乳酸共混熔体(PLLA-PDLA)属于典型的切力变稀非牛顿流体,其黏流活化能较大,表观黏度对温度变化敏感度高;随温度的升高共混熔体PLLA-PDLA的结构黏度指数减小,非牛顿指数增加。成核剂（TMP）的加入,使共混熔体PLLA-PDLA的非牛顿指数n减小、结构黏度指数Δη增大、可纺性下降,当m(TMP)/m(PLLA-PDLA)=0.5%时共混熔体PLLA-PDLA的可纺性相对较好。     

RTM用苯乙炔封端聚(甲基次乙炔基硅烷)树脂的流变特性

以可用于RTM成型的含硅炔杂化树脂体系为研究对象,深入研究了树脂体系的流变特性,并根据双阿仑尼乌斯方程,建立了流变修正模型,该模型可揭示树脂在不同温度下的黏度行为。研究表明：恒温与动态条件下的树脂流变行为符合阿仑尼乌斯流变模型,模型的计算结果和实验测试结果吻合得较好。     

PP/EPDM共混体系的辐射效应

聚丙烯和三元乙丙橡胶(EPDM)的γ辐射效应及辐射后的聚丙烯熔体流动速率的测定表明，在限定空气中聚丙烯随着辐照剂量的增加，熔体流动速率急剧下降，而三元乙丙橡胶随辐射剂量的增加，凝胶含量逐渐增加。在20kGy的剂量辐照下，凝胶含量为22．7％，加入2％的三聚异氰酸三烯丙酯，在相同的剂量辐照下，凝胶含量达到68％。在低剂量下辐照对共混物的拉伸强度影响不大，对冲击强度有很大的影响。在20kGy的剂量辐照下，加入50％EPDM的聚丙烯的缺口冲击强度由1．95kJ／m^2提高到30kJ／m^2，维卡软化温度由85．9℃提高到97．0℃。     

乙炔基封端液晶-含硅芳炔共聚树脂的固化机理

将热致性乙炔基封端液晶单体（MPBE）与含硅芳炔树脂（PSA）进行共聚,制得乙炔基封端液晶改性含硅芳炔树脂（PSA-MPBE）。采用FT-IR在线表征了PSA-MPBE树脂固化过程的结构变化,用裂解-气相色谱-质谱联用仪（Py-GC-MS）分析了其高温裂解产物,研究了其固化机理,用偏光显微镜（POM）、扫描电子显微镜（SEM）和透射电子显微镜（TEM）分析了共混树脂的相结构、断裂形貌和微观结构。结果表明：MPBE与PSA发生了共聚反应,使介晶域固定在交联网络中,形成结构均匀的以介晶相为小岛的海岛结构,PSA-MPBE树脂的断裂行为从典型的脆性断裂转变为微塑性断裂。     

二醋酸纤维素接枝聚乳酸的流变性能

采用毛细管流变仪对二醋酸纤维素接枝聚乳酸(CDA-g-PLA)的流变行为进行了研究,探讨其熔融纺丝的可纺性。结果表明：共聚物熔体为切力变稀流体,随着接枝链的增长,共聚物熔体的非牛顿指数(n)和表观黏度(ηa)减小,而稠度系数(K)、结构黏度指数(Δη)和黏流活化能(Eη)增加;随着温度的升高,非牛顿指数增大,稠度系数和表观黏度下降,共聚物加工过程黏度偏大,最佳熔融纺丝加工温度应控制在170~180°C。     

不同初始条件下聚乳酸的等温结晶动力学

用差示扫描量热法（DSC）研究聚乳酸（PLA）从熔体及玻璃态两种初始状态下的等温结晶行为,考查结晶动力学参数与结晶温度（Tc）及初始状态的关系。实验结果表明：从玻璃态结晶活化能(359 kJ/mol)较从熔体结晶活化能(103 kJ/mol)高;相应的Avrami指数n（2.3～2.7）小于从熔体的（2.5～3.1）;所测得的平衡熔点是一致的,分别为155.7 ℃（玻璃态）、156.4 ℃（熔体）;从玻璃态结晶诱导时间（ti）随着Tc升高而逐渐减小,从熔体结晶Tc=95 ℃时,出现最小ti为9.47 min;在整个Tc区间,从玻璃态结晶速率(G)都受生长控制,从熔体低温时G受生长过程控制,高温时受成核过程控制。     

甲基三苯乙炔基硅烷树脂的固化行为及其耐热性能

甲基三苯乙炔基硅烷树脂(MTPES)通过自由基机理,热聚合形成交联网络结构。TGA结果表明:氮气中树脂失重5%的温度(Td5)和800℃的质量保留率分别为695℃、92.9%,而两者在空气中却有较大幅度的下降,分别只有565℃和43.9%,聚合物表现出优异的耐热性能。通过FT-IR、DSC和流变性能研究了MTPES树脂的固化特性。利用动态DSC分析方法,采用Kissinger和Ozawa方法计算得到固化反应表观活化能分别为146.61、49.3 kJ/mol。固化反应遵循一级反应机理。     

EVA／PP共混体流变性研究

采用孟山都加工性能测试仪，测试了ＥＶＡ／ＰＰ共混体的流变性能。结果表明在２１０－２５０℃及剪切速率为６０—３×１０３／Ｓ的范围内，添加ＥＶＡ组分使共混物熔体的粘度增加，该熔体属于假塑性非牛顿流体。在剪切速率及温度较高的情况下，共混物表观粘度与组成的关系符合ｉｇηａ＝Ｗ１ｌｇη１ａ＋Ｗ２ｌｇη２ａ表示了混合律，共混物表观粘度与温度的关系符合Ａｒｒｈｅｎｉｕｓ方程。     

耐高温端乙炔基聚醚酰亚胺改性含硅芳炔树脂

采用预共聚法,以含硅芳炔树脂（PSA）和端乙炔基聚醚酰亚胺（PEI）为原料,制备了端乙炔基聚醚酰亚胺改性的含硅芳炔（PEI-PSA）树脂及其与T300碳纤维平纹布的复合材料T300/PEI-PSA。通过动态热机械分析（DMA）和X射线能谱仪（EDS）研究了溶剂、溶液浓度、反应温度对预共聚反应的影响,确定了预共聚反应的最佳条件,得到了均匀分散的PEI-PSA树脂。通过红外光谱（FT-IR）、核磁共振氢谱（¹H-NMR）、差示扫描量热（DSC）、热失重（TG）、DMA和EDS等表征了PEI、PEI-PSA树脂及T300/PEI-PSA复合材料的结构和性能。结果表明,当PEI质量分数为20%时,PEI-PSA树脂浇铸体的弯曲强度达44.5 MPa,较PSA树脂浇铸体提高了90.2%;T300/PEI-PSA复合材料的弯曲强度达602.7 MPa,较T300/PSA复合材料的弯曲强度提高了124%。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…