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1.
肺动脉/主动脉血流时间间期比定量估测肺动脉压   总被引:2,自引:0,他引:2  
为探索改良肺动脉/主动脉血流时间间期比定量估测肺动脉的方法,利用多普勒超声测量,主,肺动脉血流F值「F=PEP×PV(AT×ET),F1=PEP/AT,F2=PEP/ET,FE=PEP/(AT×ET),F4=PEP×PV/AT,F5=PEP×PV/ET」,按FPA/FAO法估测肺动脉压,并与心导管值对比。  相似文献   

2.
对彩色超声多普勒(CDFI)估测肺动脉收缩压(PASP)的实用价值进行评价,用CDFI测量23例患者的三尖瓣返流速度,推算出PASP,并与右心导管或手术中的测量值进行比较。结果表明,用三尖瓣返流法估测的PASP与右心导管或术中测得的PASP密切相关,r=0942,P<001。认为用CDFI可准确估测PASP。  相似文献   

3.
通过右心漂浮导管检测了20例临床缓解期慢性阻塞性肺病(COPD)患者的血流动力学参数,并用放射免疫分析法分别测定了体动脉和肺动脉血浆内皮素-1(ET-1)水平。结果显示:体动脉血浆ET-1水平(57.00±8.89)pg/ml小于肺动脉血浆ET-1水平(75.92±17.36)pg/ml(P<0.001):COPD并PAH组肺动脉混合静脉血浆ET-1水平的(83.90±17.12)pg/ml明显高于COPD非PAH组肺动脉混合静脉血浆ET-1水平(62.73±4.43)pg/ml(P<0.05);肺动脉混合静脉血浆ET-1水平与肺动脉平均压(PAPm)及肺血管阻力(PVR)呈显著的正相关(r=0.88,P<0.001;r=0.081,P<0.001),与心输出量(CO)、氧饱和度(SAT%)呈显著的负相关(r=-0.47,P<0.05:r=-0.79,P<0.001)。提示ET-1在COPD并PAH的发生发展中起着重要的病理生理学作用。  相似文献   

4.
应用低O2高CO2肺动脉高压大鼠模型,观察了不同低O2高CO2时间血浆内皮素含量(ET)、平均肺动脉压(mPAP)、右心室重量(RV/100gBW、RV/TV)的变化。结果显示,随低O2高CO2时间的延长,mPAP与ET均逐渐升高,二者呈良好正相关(r=0.742,P<0.001)。各实验组的RV/100gBW和RV/TV均高于对照组(P<0.01或0.001)。血浆ET浓度与RV/100gBW呈良好正相关(r=0.586,P<0.001)。表明慢性常压低O2高CO2肺动脉高压大鼠血浆内皮素浓度增加,与肺动脉高压的形成及右心室肥大有关。  相似文献   

5.
目的:探讨肺动脉高压(PH)对左心室舒张功能(LVDF)的影响及其发生机理。方法:用彩色多普勒超声心动图结合右心导管检测观察28例继发有PH先心病(CHD)病人的LVDF,并与20例无PH的CHD病人对比分析。结果:继发有PH的病人二尖瓣口血流频谱A峰流速(AV)、速度时间积分(AVI)较对照组明显增高(P<0.05~0.01),E峰流速(EV)、速度时间积分(EVI)无明显改变(P>0.05),AV/EV、AVI/EVI增大(P<0.01),左室等容舒张期(LIVRT)延长(P<0.05),且肺动脉压与AV/EV比值成中等相关(r=0.4189~0.4246,P<0.01)。结论:PH可致LVDF减退,并推测其机理可能与PH所引起的室间隔运动异常、肥厚、两室间充盈的相互影响及左室三维几何形态的改变等因素有关。  相似文献   

6.
单纯性室间隔缺损的彩色多普勒超声心动图诊断   总被引:4,自引:0,他引:4  
应用二维伪彩色多普勒超声心动图(CDE)检测单纯性室间隔缺损(IVSD)1000例,其中膜周部缺损854例,漏斗部缺损131例,肌部缺损15例。经手术证实,CDE诊断IVSD的敏感性达100%;对缺损的定位准确率为98%;对缺损大小的估侧与手术结果呈显著正相关(r=0.893,P<0.001)。与心导管测值比较,用连续波式多普勒技术估测的肺动脉收缩压与之具有良好相关性(r=0.838,P<0.001);结合M型超声测量右心室腔内径、肺动脉与主动脉根部内径比值(MPA/Ao),发现MPA/Ao>1.27和右心室增大常提示肺动脉高压。随访表明:IVSD自然闭合率26.3%,自然闭合情况与缺损部位有关  相似文献   

7.
张棣 《广西医学》1996,18(3):232-234
本应用二维及多普勒超声心动图测量64例主动脉瓣返流(AR)患的多项超声参数并结合心脏听诊进行对比研究。结果表明,各杂音组的AR峰值速度(Vmax)、AR峰值压差(PGRAD)、左室舒张末期内径(LVDd)、左室收缩末内径(LVDs)、返流束长度(ARL)均明显高于听诊未检出杂音组。Vmax与杂音的相关性最好,r=0.8110。其次分别为LVDd,r=0.7012。ARL,r=0.6512。LV  相似文献   

8.
目的:应用经胸超声心动图技术估测左心室舒张压。方法:对68例病人通过二维及脉冲多普勒记录二尖瓣、肺静脉血流及左心房参数,并与心导管检查相结合,分析超声指标与左心室舒张压的相关性。结果:(1)肺静脉参数比二尖瓣参数与左室舒张压更具相关性;(2)左室舒张末压(leftventricularenddiastolicpresure,LVEDP)明显升高时,肺静脉逆流峰速(PA)及PA的速度时间积分(PAVTI)增高,PA的持续时间(PAd)延长,肺静脉与二尖瓣A峰时限(PAdAd)延长,左房径(leftatriumdiameter,LAd)增大,左房射血分数降低;(3)PAdAd与LVEDP及LVa(左房收缩时左室压上升值)的相关系数分别为r=0.52,r=0.48,P<0.001;(4)多元回归分析示LVEDP与PAdAd,LAd,E/A,PAVTI及SFract相关,以此建立判别函数对LVEDP明显升高进行预测的敏感性是72%,特异性是78%。结论:综合肺静脉、二尖瓣血流及左房参数,可提高预测左心室舒张压的可靠性。  相似文献   

9.
多普勒超声心动图评估左心室舒张末压的研究   总被引:1,自引:0,他引:1  
目的探讨多普勒超声心动图评估左室舒张末压的有效方法与指标。方法对68例病人采用左心导管测压及经胸多普勒超声心动图检测。结果对比研究显示,联合肺静脉与二尖瓣血流频谱分析优于二尖瓣血流频谱分析,肺静脉A峰和二尖瓣A峰时限差值(PAd-Ad)与左室舒张末压实测值呈最佳相关性(r=0.72,P<0.01)。结论认为应用多普勒超声心动图测定PAd与Ad,并以其差值估测左室舒张末压,是一项简便、可靠的无创性评估左室舒张末压的方法。PAd-Ad≥0可作为临床判断左室舒张末压增高[≥2.0kPa(15mmHg)]的一项半定量指标。  相似文献   

10.
为探讨返流口面积大小对评价二尖瓣返流严重性的价值,本文对35例二尖瓣返流(MR)患者进行了多普勒超声有效返流口面积(ROA)测定及心导管检查。发现彩色多普勒血流会聚法(FCM)及多普勒血流量法测得的ROA与心导管左室造影返流程度、每搏返流量及返流分数均密切相关(r分别为0·86,0.84;0.89,0.87;0.80,0.78;P均<0.001)。两种超声方法的ROA测值总体上无显著差异(P>0.05),但FCM的结果优于多普勒血流量法,且FCM计算ROA更为方便。本文亦提出以ROA估计MR程度的定量标准  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…  相似文献   

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