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1.
陈莉  刘丽 《中国医疗前沿》2011,(12):76-76,50
目的观察桡动脉穿刺点使用TR-Band压迫型止血器压迫止血的效果。方法选择住院经桡动脉路径行冠脉介入术后患者100例,按术后是否使用压迫型止血器分为2组,观察组50例使用TR-Band动脉压迫止血器对穿刺部位进行压迫止血,另选取对照组50例使用弹力绷带对穿刺部位进行包扎止血,观察两组患者穿刺点出血情况,以及局部并发症的发生率,包括肢体肿胀麻木、桡动脉急性闭塞、迷走反射性晕厥发生率。结果桡动脉急性闭塞及迷走反射性晕厥发生率,差异无统计学意义(P〉0.05),而观察组肢端肿胀、麻木发生率及穿刺点出血发生率明显低于对照组(P〈0.05)。结论应用压迫止血器明显优于弹力绷带压迫,且具有良好止血效果,操作简便,血管并发症少。  相似文献   

2.
周琳  任继刚  李嘉俊 《西部医学》2013,(12):1828-1830
目的 探讨经桡动脉穿刺行介入性冠脉诊疗术后局部止血相关处理方法.方法 将324例经桡动脉穿刺行冠脉诊疗术后的患者随机平均分成对照组、观察A组、观察B组各108例,对照组患者术后使用传统止血方法,观察A组患者术后采用弹力纱布止血,B组使用桡动脉止血器压迫4小时后换弹力纱布止血.观察3组患者穿刺出血、手部瘀肿及疼痛情况.选择出现手部中度瘀斑的32例病例,再次随机分为安慰组10例和实验A、B组各11例,实验A组使用硫酸镁加高糖维生素B12外敷,实验B组在A组基础上加利多卡因外敷,观察3组患者瘀肿的消失度.结果 观察B组穿刺出血、手部瘀肿及疼痛改善情况均低于观察A组,且明显低于对照组,差异有统计学意义(P<0.05);实验B组手部瘀斑缓解高于A组,差异亦有统计学意义(P<0.05).结论 使用桡动脉止血器止血后换用弹力纱布继续止血效果确切.术后局部瘀斑处理时硫酸镁加高糖维生素B12联合利多卡因外敷可明显改善预后.  相似文献   

3.
目的评价经桡动脉行冠状动脉造影术(CAG)后桡动脉穿刺部位应用动脉止血器止血的效果和安全性。方法经桡动脉途径行CAG的200例患者,随机被分为两组,实验组术后采用动脉止血器压迫止血,对照组患者术后均使用传统止血方法。结果两组伤口渗血、皮下血肿、迷走神经反射性晕厥发生率,差异无统计学意义(P〉0.05),而肢端肿胀、麻木、发绀发生率低于对照组,两组相比较差异具有显著性(P〈0.01)。结论经桡动脉行冠状动脉造影术(CAG)后桡动脉穿刺部位应用动脉止血器止血安全有效且易操作。  相似文献   

4.
目的 比较经桡动脉穿刺行冠状动脉介入术后绷带压迫和螺旋压迫器压迫止血的效果.方法 将经桡动脉途径行冠状动脉介入术的200例患者随机分为观察组(螺旋压迫器压迫止血,100例)和对照组(绷带包扎止血,100例);比较2组的出血情况、肢体肿胀程度.结果 观察组止血成功率及避免肢体肿胀均优于对照组(P<0.05).结论 桡动脉螺旋压迫器压迫止血可缩短止血时间,减少穿刺点出血和手背部肿胀.  相似文献   

5.
目的:比较TR-Band充气止血绷带两种不同放气方式对经桡动脉冠状动脉介入术后穿刺部位的影响.方法:将经桡动脉行冠状动脉介入术后患者395例随机分为A组206例和B组189例.A组术后压迫1h开始初次放气,6~8h放完;B组术后压迫4h开始初次放气,8~10 h放完.比较2组患者末梢经皮血氧饱和度、压迫总时间、穿刺部位并发症发生情况.结果:2组患者末梢经皮血氧饱和度均在正常范围,差异无统计学意义(P>0.05),A组压迫总时间显著少于B组(P<0.01).2组出血、血肿发生率差异均无统计学意义(P>0.05);A组肿胀、淤斑及患者主观不适情况发生率均低于B组(P<0.05~P<0.01).结论:TR-Band充气止血绷带压迫1h后开始放气,6~8h放完的放气方式比较合理,既可有效压迫止血,又可减少相关并发症的发生.  相似文献   

6.
目的:探讨创可贴纱块双压法在经桡动脉行冠状动脉介入治疗后穿刺局部创口加压止血的效果。方法选择心血管内科100例经桡动脉行冠心病介入治疗的患者,按住院先后分为对照组和观察组,各50例。对照组患者在经桡动脉行冠心病介入拔鞘管后穿刺部位采用桡动脉介入穿刺部位止血器压迫止血的方法,观察组患者采用创可贴联合纱块双压法进行加压止血的方法。观察比较两组患者在按压止血时间、渗血、淤血、肢端肿胀等情况。结果两组平均持续加压止血时间观察组明显短于对照组,在渗血、淤血、肢端肿胀方面的发生率明显低于对照组,两组比较有明显差异性(P<0.05),具有统计学意义。结论采用创可贴联合纱块双压法应用于穿刺拔鞘后局部创口的压迫止血时间明显缩短,止血效果好,对静脉回流受阻小,能降低拔鞘后的并发症,提高患者的舒适度,减轻病人的经济负担,能代替桡动脉介入穿刺部位止血器的应用,且能适应于各种穿刺创口的加压止血,能增加社会效益和经济效益。  相似文献   

7.
路世红 《中国现代医生》2010,48(28):103-103,105
目的探讨经桡动脉穿刺行冠脉造影及介入治疗术后使用自制桡动脉辅助压迫止血垫后的效果。方法将356例经桡动脉穿刺行冠脉造影及介入治疗后的患者随机分成两组。对照组180例患者术后使用传统止血方法,观察组176例患者术后使用自制桡动脉辅助止血垫压迫止血。观察两组患者穿刺口压痛、瘀血、手部肿胀、局部过敏情况及患者舒适度。结果观察组术后穿刺处的各种并发症均明显优于对照组,两组差异有统计学意义(P均〈0.05)。结论使用自制桡动脉辅助压迫止血垫在冠脉介入术后对桡动脉止血效果满意,穿刺周围皮肤并发症少,患者舒适度明显提高,不适感时间缩短而且价格低廉,值得临床推广。  相似文献   

8.
目的 探讨动脉压迫止血器在桡动脉入路冠状动脉介入治疗术后的应用.方法 200例经桡动脉行冠状动脉介入治疗的患者,随机分为两组,对照组96例,采用传统弹性粘贴固定绷带压迫止血;观察组104例,采用动脉压迫止血器压迫止血.比较两组术后平均止血时间、并发症发生率以及患者肢体疼痛程度等指标.结果 所有患者均顺利完成冠状动脉介入治疗,观察组平均止血时间(348.4±18.7) min,与对照组平均止血时间(357.1±21.5) min相比,差异无统计学意义(P>0.05);观察组血管并发症肢体肿胀、麻木、发绀发生率,创口渗血、血肿发生率,患者肢体疼痛评分均明显低于对照组,差异有统计学意义(P <0.05或0.01).结论 动脉压迫止血器与传统弹性粘贴固定绷带均有较高的止血成功率,但前者具有较低的并发症发生率,并可以减轻患者疼痛,增加患者舒适感.  相似文献   

9.
目的 探讨经桡动脉途径行冠状动脉介入治疗术(PCI)治疗患者术后应用替罗非班后压迫止血的减压时间和如何通过临床护理观察干预减少桡动脉穿刺并发症的发生.方法 600例经桡动脉行PCI治疗的患者,其中317例患者术后使用替罗非班.所有患者均使用TR Band压迫止血器对桡动脉进行压迫止血.按替罗非班是否使用和止血减压时间不同分为对照组(293例),替罗非班使用A组(137例)、B组(180例)共三组,观察三组术后止血效果及压迫止血的并发症.结果 PCI术后应用替罗非班明显增加桡动脉穿刺点渗血,局部血肿等并发症的发生,通过调整减压时间能显著降低此类并发症的发生.  相似文献   

10.
目的总结一次性桡动脉充气式止血器(TR Band)的临床应用及护理方法 ,提高TR Band止血器使用效果,减少桡动脉穿刺并发症。方法回顾性分析内科2011年12月—2013年6月经桡动脉冠状动脉介入患者114例,所有患者术前给予心理护理、充分沟通,告知桡动脉穿刺益处及可能并发症和术后注意事项,术中密切观察,术后立即拔除桡动脉鞘,按照TR Band止血器使用方法注入13~15 ml气体,最多不超过18 ml压迫止血,分别于术后每2 h放气2 ml,放气8~10 ml后观察,10~20 h去除压迫器。观察TR Band对桡动脉穿刺处压迫止血效果、并发症及患者的适应程度等。结果所有患者均有效止血,不影响患者休息体位及大小便,其中并发手部肿胀10例,皮肤局部压伤1例,桡动脉闭塞2例,压迫处不同程度疼痛25例,其他患者无任何并发症及不良反应。结论 TR Band用于桡动脉穿刺后压迫止血操作简单、疗效可靠、安全、不良反应少。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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