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1.
目的:观察手术治疗儿童集合不足型间歇性外斜视的疗效,探讨影响术后效果的因素。方法:收集2012年3月至2015年6月南昌大学第二附属医院行斜视矫正手术的378例集合不足型间歇性外斜视患儿的病历资料,记录比较手术前后患儿的眼位及双眼视功能情况,术后随访6~12个月。结果:378例集合不足型间歇性外斜视患儿中有302例斜视度在25△~55△,术式为双眼外直肌后徙或单眼外直肌后徙联合内直肌缩短,术后正位率为91.06%,两种术式手术效果无统计学差异;76例患儿斜视度≥60△,手术方式选择双眼外直肌后徙联合单眼内直肌截除术,术后正位率为85.53%。患儿手术前后的视近、视远斜视度以及其差值的变化均有统计学意义(P < 0.05),术后双眼视功能亦较术前有明显提升。结论:双眼外直肌后徙术或单眼外直肌后徙联合内直肌缩短术均为治疗集合不足型间歇性外斜视的有效手术方式。  相似文献   

2.
目的探讨集合不足型外斜视的手术治疗方式。方法回顾性分析2015年至2019年3月我院手术的58例集合不足型外斜视患者的临床资料,总结患者的斜视度数与手术方式的关系。结果看近斜视度≤30△的15例患者行单眼内直肌缩短术,术后近期正位(≤±8△)者11例,正位率为:73.3%;正位患者中有8例术后3月(远期)复诊时出现小的外斜复发(外斜10~18△)。看近斜视度35△~80△的患者18例选择单眼外直肌后徙联合内直肌缩短;术后近期正位(≤±8△)者15例,正位率为:83.3%;远期正位(≤±8△)12例正位率为66.67%;欠矫6例(10△~15△),无过矫者。看近斜视度85△~110△的患者25例选择双眼外直肌后徙+单眼内直肌缩短,术后近期正位(≤±8△)者21例,正位率为:84.0%;看近正位看远过矫2例(10△~14△);看远正位看近欠矫2例(12△~15△)。远期正位(≤±8△)19例正位率为76.0%,1例过矫者发生继发性内斜视,5例欠矫。所有患者手术前后看近及看远的斜视度,及看近、看远的斜视度差值有统计学意义。(P0.05)术前13例患者有双眼视,术后增加到24例。结论集合不足型外斜视应根据看近斜视角度的大小以及看近看远的斜视度差值选择具体手术方式。手术原则当以加强内直肌为主,术后看近欠矫看远正位者远期易发生眼位回退,看远轻微过矫者眼位不易回退,但过矫要避免发生继发性内斜视。  相似文献   

3.
目的观察双眼外直肌后徙与单眼外直肌后徙联合内直肌缩短术治疗间歇性外斜视病人术后不同时期眼位,探讨其矫正效果。方法选择195例于我院手术的间歇性外斜视病人,依据不同的手术方式分为A、B两组,分别行双眼外直肌后徙术、单眼外直肌后徙联合内直肌缩短术。比较两组术后0.5、1.5、3.0年的眼位正位率。结果术后0.5年,A组眼位正位率低于B组,差异有显著性(χ2=8.83,P〈0.05);术后1.5年,两组眼位正位率比较差异无显著性;术后3.0年,A组眼位正位率高于B组,差异有显著性(χ2=6.29,P〈0.05)。结论术后短期内单眼外直肌后徙联合内直肌缩短术眼位矫正效果优于双眼外直肌后徙术,然而,后者术后长期眼位正位率高于前者。  相似文献   

4.
儿童间歇性外斜视95例手术疗效分析   总被引:2,自引:1,他引:1  
目的观察儿童间歇性外斜视的手术治疗效果。方法对95例儿童间歇性外斜视,在氯胺酮全身麻醉下进行双眼外直肌后徙术或单眼外直肌后徙加同一眼的内直肌缩短术,并进行了6-30个月的随访观察。结果术后85例患者眼位正位,占手术总数的89.47%,术前47例无双眼单视功能的患者有28例恢复了双眼单视功能,占术前无双眼单视功能的59.57%。结论手术是治疗儿童间歇性外斜视的有效方法。  相似文献   

5.
目的 探讨不同类型间歇性外斜视手术前后双眼视功能的变化及不同手术方式对手术效果的影响.方法 将120例间歇性外斜视病人按照斜视类型分为基本型(29例)、集合不足型(80例)、分开过强型(11例),对3种类型病人术后正位率、立体视功能恢复率、融合功能恢复率进行比较.集合不足型80例病人根据手术方式是单或双眼外直肌后徙术,还是单眼外直肌后徙加内直肌缩短术分为A、B两组,比较两组术后正位率、融合功能恢复率、立体视功能恢复率及残余性外斜视、连续性内斜视发生率.结果 3种类型间歇性外斜视术后正位率差异均无显著性(P>0.05).集合不足型立体视功能恢复率、融合功能恢复率与其他两型间比较差异均有显著性(χ2=3.86~6.47,P<0.05),而基本型和分开过强型间差异无显著性(P>0.05).A、B两组术后正位率、术后融合功能恢复率、立体视功能恢复率、残余性外斜视率比较差异有显著性(χ2=4.75~6.70,P<0.05),而连续性内斜视率两组间差异无显著性(P>0.05).结论 集合不足型间歇性外斜视术后双眼视功能恢复差,手术应主要缩短内直肌以加强集合能力,一般选择单眼外直肌后徙加内直肌截除术,以达到术后较高的正位率和恢复一定双眼视功能目的.  相似文献   

6.
目的:观察双眼外直肌后徙术治疗儿童类似分开过强型间歇性外斜视的手术疗效。方法回顾性分析行双眼外直肌后徙术治疗儿童类似分开过强型间歇性外斜视22例连续性病例的病历资料。采用三棱镜加交替遮盖法测量患儿,经1 h诊断性遮盖前后注视6 m及33 cm调节性视标第一眼位的斜视度。检查患儿的融合功能和立体视锐度。依据诊断性遮盖后测量的最大看远斜视度,行双眼外直肌对称性定量后徙术。术后1d、1个月、3个月、6个月检查患儿的斜视度和双眼视功能。疗效评价标准为斜视度≤±8 PD为正位。结果22例诊断性遮盖前看远与看近斜视度的差值为(17.3±7.9)PD,诊断性遮盖后看远与看近斜视度的差值为(0.5±3.3)PD。双眼外直肌后徙量(7.2±1.2)mm。术后平均随访(8.6±5.4)月。末次随访的正位率为81.8%(18/22)、过矫率为4.5%(1/22)、欠矫率为13.6%(3/22)。手术前后融合和立体视锐度的差异无统计学意义(P>0.05)。结论根据诊断性遮盖后测量的最大看远斜视度行双眼外直肌后徙术,可有效的矫正儿童类似分开过强型间歇性外斜视。  相似文献   

7.
目的 分析继发性内斜视手术方式及二次手术前、后双眼视觉.方法 对59例均有外斜视手术矫正病史的继发性内斜视进行手术治疗并观察两次手术术前、术后双眼视觉的变化.结果 对有外转受限和侧方非共同性的患者,采用外直肌复位或缩短复位,不足联合内直肌后徙术,对无外转受限和侧方非共同性的患者,采用内直肌后徙,不足联合外直肌复位或缩短复位术.间歇性外斜视过矫所致的继发性内斜视对双眼视觉损害更大,手术前、后双眼视觉对比有统计学意义.结论 外直肌复位联合内直肌后徙是治疗继发性内斜视的有效方式,尽早手术治疗,有利于双眼单视功能的恢复.  相似文献   

8.
目的:比较基本型间歇性外斜视患者2种术式临床疗效的差异。方法:回顾分析南京医科大学第一附属医院手术治疗的基本型间歇性外斜视患者68例,因术式不同随机分为2组,A组36例,行双眼外直肌等量后徙术;B组32例,行单眼外直肌后徙联合内直肌截除术。所有患者术后随访时间>1年,分别比较2组基本型间歇性外斜视的患者手术矫正后在眼位正位率、斜视度回退量、近立体视功能恢复率方面的差异。结果:A、B组术后1周眼位正位率无统计学意义(χ2=0.051,P=0.822);术后1年B组斜视度回退明显,A组眼位正位率高于B组,有统计学意义(χ2=4.600,P=0.032);A、B组术后1年近立体视功能恢复率比较差异无统计学意义(χ2=0.148,P=0.700)。结论:基本型间歇性外斜视患者采用不同手术方式,术后1周正位率无差异;术后1年单眼一退一截手术方式患者斜视回退明显,双眼外直肌后徙术临床疗效稳定。  相似文献   

9.
目的:探究不同术式对Ⅴ型外斜视的临床疗效及其远期效果观察。方法:选取进行手术治疗的Ⅴ型外斜视患者230例为研究对象,按照术前不同检查结果实施不同手术方式。同时需按照AC/A值大小,在矫正水平斜视时取双眼外直肌后徙术和或内直肌缩短术,当存在较大的水平斜视度,则需联合实施非主导眼内直肌缩短。结果:230例患者中,实施水平肌的斜行重叠的6例,是单纯行单眼水平肌手术,无下斜肌亢进患者;实施水平直肌垂直移位术的30例,是下斜肌亢进为(+)的患者,V征度数术前为8△~10△,实施单侧下斜肌切断术联合水平直肌加强减弱术105例,是下斜肌亢进为(++)的患者;V征度数是10△~25△,实施双侧下斜肌切断术联合直肌移位术的89例,是下斜肌亢进为(+++)患者,V征相差分别为25△~45△。术后1年复查,对手术效果满意者占190例(82.61%),双眼上中下注视均位正;2例(0.09%)过矫,5例V征(+),依旧存在高低眼位;欠矫者占5例(2.17%),水平位依旧有外斜视。此组患者中,术前存在立体视者45例(19.57%),双眼视者64例(27.82%);术后经随访发现,存在立体视者92例(40.00%),双眼视者130例(56.52%),20例自发产生双眼单视功能,未经任何训练,其中10例6岁,5例8岁。结论:针对V型外斜视患者,下斜肌亢进是主要的发病原因,按照亢进程度不同选择不同手术方式,并加以增强双眼视功能训练,从而获得双眼视,改善患者的生活质量,具有临床应用价值。  相似文献   

10.
目的 观察外直肌超常量后徙固定在知觉性外斜视手术中的远期疗效,分析其应用价值.方法 回顾性分析我科2012年5月至2013年9月行外直肌超常量后徙固定的知觉性外斜视病例12例.外斜视度数均>50△,患眼固视功能差.在斜视眼行外直肌超常量后徙固定(缝合于原肌止点后12.0 mm)联合内直肌缩短术(4.0~7.0 mm),观察术后眼位、眼球运动、眼面外观及视功能远期疗效.结果 随访13 ~ 27个月后,12例患者术后眼位正位,眼球外转稍有受限;眼面外观良好;均获得较稳定的患眼固视能力,但未建立明确的双眼视功能.结论 外直肌超常量后徙固定稳定了后徙外直肌的位置,减少了手术肌肉条数,具有安全可行、远期疗效稳定等优点.  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

20.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

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