2000～2003年我院收治的宫外孕年发生率变化趋势分析

目的：了解本地区宫外孕发生率变化趋势、主要原因及变化特征，方法：采用回顾性资料分析方法，对我院收治的妇科手术患者及其中的宫外孕患者的临床资料进行分析结果：宫外孕占妇科手术的年发生率2000年为8．9％，2001午为13．9％，2002年10．0％，2003年为24．1％．呈现逐年上升趋势。发病年龄由2000年31岁左右，以30岁-39岁年龄段为多：2002年24岁左右。2003年22岁左右，即发病年龄趋于年轻化。发病人群由2000年的城市人群占主要转变为二者基本持平，发病的主要原因仍然为妇科炎症，4年间无明显变化。结论：4年间本地区宫外孕占妇科手术的年发生率呈现上升趋势，发病年龄趋于年轻化．发病人群由城市人群占主要转变为二者基本平衡。发病的主要原因仍然为妇科炎症。     

1981～2010年鼻咽癌高发地区鼻咽癌患者发病年龄变化分析

目的 了解1981 ～2010年鼻咽癌高发地区鼻咽癌患者的发病年龄变化情况,分析变化原因,为制订鼻咽癌防治措施提供参考.方法 收集1981年1月至2010年12月14 993例首次住院初治鼻咽癌患者的病历资料;用Cox-Stuart趋势性检验法分析发病年龄变化趋势,并比较不同年份男女性患者的发病年龄,以及不同户籍、不同省区患者的发病年龄.结果 1981 ～2010年鼻咽癌男女比例为2.76∶1;1981～ 1986年、1987 ～1992年、1993 ～1998年、1999 ～ 2004年男性发病年龄均明显高于女性(P＜0.05);2005 ～ 2010年男女发病年龄比较,差异无统计学意义(P＞0.05);Cox-Stuart趋势检验结果显示1981 ～2010年鼻咽癌患者发病年龄呈上升趋势(P＜0.05).非农业患者发病年龄大于农业患者(P＜0.05),广西患者发病年龄大于广东患者(P＜0.05).结论 鼻咽癌高发地区的鼻咽癌发病年龄呈上升趋势,应当采取一级预防措施.     

4255例消化道恶性肿瘤的统计分析

目的　调查本地区消化道恶性肿瘤的年龄、性别、疾病构成及血型分布特点。方法　收集 42 5 5例消化道恶性肿瘤患者的相关资料进行统计分析。结果　消化道恶性肿瘤高发年龄为 5 0～ 60岁。发病居前 5位的肿瘤依次是食管癌、胃癌、贲门癌、直肠癌和结肠癌。常见消化道肿瘤除直肠癌女性发病高于男性外 ,其余 4种肿瘤男性发病均高于女性。与ABO血型的关系 ,与正常对照相比 ,男性 :A型血胃癌、贲门癌、B型血结肠癌发生频率较高 ,女性 :B型血贲门癌发生频率较高。女性O型血食管癌、贲门癌发生频率较低 ;男女AB型血直肠癌发生频率均较低。χ2 检验P <0 .0 5～P <0 .0 1。结论　消化道肿瘤中 ,食管肿瘤和胃肿瘤最常见 (约占 88% ) ,5 0～ 60岁是消化道肿瘤的高发年龄 ,应重点防治。不同肿瘤在不同血型分布的频率似与肿瘤部位及性别有关。     

大肠癌临床特征的变化趋势

目的:分析广东地区大肠癌临床特征的变化趋势,探讨大肠癌发病模式的变化规律。方法:总结分析广东四个地区五间医院1988年~2008年收治的8 172例大肠癌患者的临床资料。结果:2006~2008年段与1988~1990年段比较,中位发病年龄从52岁上升至60岁,上升了8岁,性别比由1.7∶1下降到1.4∶1,右半结肠癌从19.7%上升到25.8%,DukesA期的比例由4.5%升到7.7%。结论:近20年中位发病年龄上升了8岁,右半结肠癌比例上升,发病部位右移提示应重视全结肠镜检查。     

某院2002～2007年恶性肿瘤住院病例统计分析

目的:分析恶性肿瘤患者的年龄﹑性别及种类构成特点,为肿瘤防治工作提供依据。方法:选择南通大学附属医院2002～2007年6年住院恶性肿瘤15570例,对相关资料进行Excel统计学分析。结果:恶性肿瘤高发年龄为50～70岁,50岁以上老年人所占构成比为79.18%。男女性别比1.45:1,发病居前3位的依次为支气管肺癌、胃癌、肝和肝内胆管癌。高发年龄支气管肺癌为60～69岁,胃癌为60～69岁,肝胆恶性肿瘤为50～59岁。结论:恶性肿瘤发病呈逐年增长的趋势,肿瘤发病存在性别、年龄差异(P<0.05),根据恶性肿瘤发病特征对高危人群做好防治工作是降低发病率、提高生存率的关键。     

血清丙氨酸转氨酶在汉族中年人群中随年龄的变化趋势

 目的  了解汉族中年人群中血清丙氨酸转氨酶(alanine aminotransferase,ALT)随年龄增长的变化趋势。方法  在泰州人群健康跟踪调查的基线中选取2012年3月至2013年2月的资料,对11 553名30～64岁常住居民的ALT与年龄进行横断面分析。年龄按五分位数分成5组(30～41岁、42～45岁、46～51岁、52～57岁、58～64岁),多因素调整后,比较各年龄组的ALT水平。结果  男性ALT水平(25.35±13.24) IU/L高于女性ALT水平(19.80±9.94) IU/L,差异有显著统计学意义(P<0.01)。5组男性ALT水平分别是29.49、27.04、25.93、24.26和22.01 IU/L,组间差异有显著统计学意义(P<0.01);5组女性ALT水平分别是18.35、18.23、19.86和21.60、21.00 IU/L,组间差异有显著统计学意义(P<0.01)。汉族中年男性中ALT水平随着年龄增长而降低,而女性ALT水平在52～57岁出现峰值。在调整了吸烟、饮酒、教育程度、体质指数等因素后,男性和女性的ALT水平随年龄增长的变化趋势基本不变。结论  在30～64岁汉族人群中,血清ALT水平随年龄的变化趋势在男性和女性中不同。     

2001-2010年六灶社区恶性肿瘤发病率分析

目的:了解六灶社区居民近10年来主要恶性肿瘤发病趋势和流行病学特征。方法:对六灶社区2001-2010年主要恶性肿瘤发病资料进行年龄、性别、时间趋势上的分析。结果:10年来六灶社区居民肿瘤发病率居于前6位的是肺癌、胃癌、肝癌、直肠癌、乳腺癌、结肠癌,男性发病率呈明显上升趋势,女性则保持相对平稳态势。结论:上海市六灶社区肺癌、肝癌、胃癌是发病率最高的恶性肿瘤,40岁以上年龄段人群是六灶社区恶性肿瘤的重点防治人群。只有对重点人群进行早发现、早诊断、早治疗,才能有效控制肿瘤发病。     

诸城市1998～2007年恶性肿瘤发病情况回顾性分析

目的了解中小城市恶性肿瘤发病的基本情况,为肿瘤防治工作提供基本数据和参考依据。方法以潍坊地区诸城市二级医院经病理确诊的恶性肿瘤患者为研究对象,初步分析这一地区人群恶性肿瘤的发病趋势、发病病因。结果 10年间经病理确诊的恶性肿瘤计8490例,男女之比1.57:1,排序前5位的分别是胃癌、肺癌、乳腺癌、食道癌、结肠癌。胃癌、肺癌分别占居第1位和第2位。吸烟、饮酒分别是肺癌、食道癌的主要致病因素。癌前病变与相关肿瘤发病相关。结论中小沿海发达城市肿瘤发病情况不容乐观,政府应加大肿瘤防治工作的资金投入。     

2004～2008年首次住院前10位恶性肿瘤构成分析

目的分析首次住院恶性肿瘤患者的年龄、性别及种类构成特点,为肿瘤防治工作提供依据。方法选择汕头大学医学院附属肿瘤医院2004～2008年5年首次住院恶性肿瘤20067例,对相关资料进行综合分析。结果恶性肿瘤高发年龄为45～64岁,占构成比为56．31％。男女性别比1．55：1,首次住院居前3位的依次为食管癌、肺癌和鼻咽癌;65岁及以上年龄组是食管癌、肺癌和胃癌;45-64岁年龄组是食管、肺和鼻咽恶性肿瘤;25～44岁年龄组是鼻咽、乳腺癌和宫颈癌。结论食管癌、肺癌、鼻咽癌和胃癌是本地区常见肿瘤,中老年组患病率高,根据恶性肿瘤发病特征对高危人群做好防治工作是降低发病率、提高生存率的关键。     

1627例肺癌的发病年龄趋势分析

目的 分析1980～2008年肺癌发病年龄变化趋势与规律,为肺癌防治提供依据. 方法 收集、整理梧州红会医院肿瘤科1980～2008年共1627例肺癌病例资料,对其进行分析. 结果年龄分布呈正态分布.20～和40～岁年龄组构成比分别从1980～年的6. 77%和44.79%上升至2000～年的7.90%和49.14%,经趋势检验有统计学意义(P<0.01);说明其构成比呈现上升趋势.女性在80～ 年代的构成比由17.84%,上升至21世纪的27.61%, P<0.01.结论 近年肺癌发病年龄呈现年轻化趋势.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.