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1.
异位妊娠期待治疗适应证的初步探讨   总被引:2,自引:0,他引:2  
对经腹镜检查、剖腹手术或B超检查确诊的65例稳定型妊娠有性研究。初步探讨并总结了异位妊娠期待治疗的适应证为:(1)一般情况好,症状不明显;(2)血β亚单位-绒毛膜促性腺激素(β-hCG)呈现持续性下降;(3)尿hCG弱阳性或阴性(4)基础体温<26.6℃(口表);(5)诊断性刮宫(诊刮)的子宫内膜病理表现为增生反应;(6)输卵管妊娠完全流产型。凡符合上述第一条及以后任何一条者,均可进行期待治疗。但  相似文献   

2.
目的探讨诊断性刮宫(简称诊刮)结合血人绒毛膜促性腺激素(hCG)测定,在诊断早期异位妊娠中的作用。方法对临床症状、体征及实验室检查可疑异位妊娠的61例患者进行了诊断性刮宫、病理检查及血hCG测定。结果子宫刮出物有绒毛组织,确诊为子宫内妊娠患者有17例;刮出物无绒毛组织,24小时后血hCG继续升高诊断为异位妊娠患者26例;子宫刮出物无绒毛组织,24小时后血hCG下降者18例,其中有子宫内妊娠也有异位妊娠患者,多数毋需处理。结论采用诊刮结合血hCG测定可以鉴别子宫内妊娠和早期异位妊娠,并为进一步处理提供参考依据。  相似文献   

3.
目的 探讨诊断性刮宫(简称诊刮)结合血人绒毛膜促性腺激素(hCG)测定,在诊断早期异位妊娠中的作用。方法 对临床症状、体征及实验室检查可疑异位妊娠的61例患者进行了诊断性刮宫、病理检查及血hCG测定。结果 子宫刮出物有绒毛组织,确诊为子宫内妊娠患者有17例;刮出物无绒毛组织,24小时后血hCG继续升高诊断为异位妊娠患者26例;子宫刮出物无绒毛组织,24小时后血hCG下降者18例,其中有子宫内妊娠也  相似文献   

4.
腹腔血β-人绒毛膜促性腺激素测定诊断异位妊娠的价值   总被引:1,自引:0,他引:1  
腹腔血β-人绒毛膜促性腺激素测定诊断异位妊娠的价值许岚,陈竹钦(第三军医大学大坪医院妇产科)630042静脉血β-人绒毛膜促性腺激素(β-hCG)测定是诊断异位妊娠的敏感指标,但有些患者初次就诊时血β-hCG正常,易漏、误诊,本文比较了妇科内出血患者...  相似文献   

5.
隋龙  王成海 《上海医学》1999,22(6):358-360
目的 探讨血浆抑制素在异位妊娠中的含量变化及临床意义。方法 设置宫内妊娠组(26例)和异位妊娠组(18例),并设对照组,应用改良的INH放射免疫测定(RIA)方法测定早期宫内及异位妊娠血浆INH含量变化,并将血浆β-hCG与INH浓度进行相关性分析。结果 1.异位妊娠组血交INH和β-hCG均地宫内妊娠组,差异显著,P均〈0.05;2.宫内妊且血乐INH与β-hCG间呈显著相关关系:r宫内=0.4  相似文献   

6.
米非司酮治疗异位妊娠临床观察   总被引:3,自引:0,他引:3  
尚学英 《中原医刊》2001,28(7):28-29
异位妊娠是严重危害妇女生命和健康的常见妇科疾病,近年来,国内外的发病率均呈逐年上升趋势[1],对异位妊娠的保护性药物治疗,常用氨甲喋呤(MTX),其效果确切,但其毒性反应较大。据文献报道[2],米非司酮可用于治疗输卵管妊娠,药物副作用小,效果满意。我们自1996年12月开始试用米非司酮治疗异位妊娠,取得了满意疗效,现报道如下。 1 资料与方法 1.1 研究对象:自1996年12月到1999年12月确诊异位妊娠35例。每例诊断均根据病史、妇科检查、血β-hCG及B超检查,其中血β-hCG采用放射免疫法…  相似文献   

7.
目的 探讨保守治疗异位妊娠以达到最低限度的外科干预和药物不良反应,提供新的治疗方法。方法 采用宫腔注射氨甲喋呤异位妊娠以血清β-绒毛膜促性腺激素(β-HCG)水平评价治疗效果,β-HCG下降至正常值为治愈,结果 16例中输卵管妊娠15例,有宫角妊娠1例,均为未破裂型。治疗后72h血清β-HCG水平下降较治疗前有显著差异,治愈15例(93.7%),失败1例(6.3%)。住院天数4-22d,平均11.  相似文献   

8.
腹腔血与静脉血β-HCG值测定在诊断异位妊娠中的应用   总被引:1,自引:0,他引:1  
腹腔血与静脉血β-HCG值测定在诊断异位妊娠中的应用田晶,惠宁,刘彦,周俊,戎霖随着人绒毛膜促性腺激素(HCG)测定技术的推广,β-HCG亚基的放射免疫测定法已用于异位妊娠的临床诊断。我们测定了34例可疑异位妊娠患者腹腔血和静脉血β-HCG含量,以探...  相似文献   

9.
目的:探讨快速准确监测血β-HCG的变化对氨甲喋呤(MTX)治疗异位妊娠效果的临床意义。方法:采用全自动微粒子化学发光检测系统血β-HCG的含量。结果:经MTX单次肌内注射后,患者血β-HCG含量不断下降直至恢复正常。结论:微粒子化学发光技术检测血β-HCG准确及时,是选择异位妊娠治疗方案及观察MTX疗效的有效手段。  相似文献   

10.
米非司酮治疗异位妊娠47例   总被引:64,自引:0,他引:64  
为探讨米非司酮治疗异位妊娠的效果及适应症,将47例宫外孕分三组服药。结果29例有效,18例手术治疗。观察手术治疗者输卵管妊娠结局,腹腔出血量及病灶部位病理变化。分析原因,发现疗效与药物剂量,服药前血β-hCG高低及手术干预过早有关。认为大剂量米非司酮治疗异位妊娠具有简便、安全、无毒副作用等优点,是异位妊娠保守治疗的一种较好方法。适合于生命体征平稳,无剧烈腹痛,血β-hCG〈10ng·ml^-1,盆  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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