跟骨关节内骨折的手术治疗

目的:探讨跟骨关节内骨折的手术治疗效果。方法:回顾性总结27例跟骨关节内骨折切开复位钢板内固定的手术治疗方法。结果:本组27例31足均随访5个月~24个月,平均随访13个月。骨折全部愈合,术后按Maryland足部评分系统评价,优6足(19.4%),良21足(67.7%),可4足(12.9%),优良率87.1%。结论:切开复位内固定是治疗跟骨关节内骨折的有效方法。     

AO钢板内固定治疗跟骨骨折

目的总结跟骨关节内骨折手术治疗体会,为提高手术疗效、改进手术方法提供借鉴。方法对31例（36足）移位的跟骨关节内骨折切开复位AO跟骨钢板内固定,疗效评价根据Maryland Foot Score足部评分标准。结果31例（36足）均获随访12～36个月,患者足功能优良27例（32足）,总优良率88.89%。结论跟骨关节内骨折切开复位,AO钢板内固定是比较好的治疗方法。     

可塑性钛合金钢板治疗跟骨关节内粉碎性骨折

目的:总结跟骨关节内粉碎性骨折切开复位应用可塑性钛合金钢板内固定的手术治疗经验。方法:对20例22足跟骨关节内粉碎性骨折进行切开复位内固定治疗,内固定物为可塑性跟骨钛合金钢板,疗效评定标准采用Maryland足部评分系统。结果:20例22足骨折术后均得到随访,随访时间6～18个月,平均13个月,患足功能优12例(54.5%),良8例(36.4%),可2例(9.1%),优良率为90.9%。结论:切开复位可塑性钛合金钢板内固定是治疗Sanders 3、4型跟骨关节内粉碎性骨折比较安全、有效的方法。     

跟骨重建钢板内固定治疗跟骨关节内骨折的临床观察(附27例报告)

目的 探讨跟骨重建钢板内固定治疗跟骨关节内骨折疗效.方法 采用跟骨外侧"L",形切口入路,切开复位重建钢板内目定,治疗跟骨关节内骨折27例(30足).结果 所有患者均获6～18月随访,根据Maryland足部评分系统,优16足,良12足,可2足,优良率93.3%.结论 跟骨关节内移位骨折采用切开复位重建钢板内固定治疗,能早期功能锻炼,减少并发症.     

跟骨钢板治疗跟骨关节内骨折

目的:总结跟骨钢板治疗跟骨关节内骨折的临床疗效。方法:跟骨关节内骨折36例(42足),根据Sanders分型:Ⅱ型18足,Ⅲ型13足,Ⅳ型11足。采用扩大的外侧L形入路行切开复位钢板内固定。根据手术前后X线片对跟骨的长、宽、高以及跟骨Bhler角和Gissane角进行评价。采用Maryland足评分系统评价临床功能。结果:所有患者术后获得随访,时间6～36个月,平均18个月。术后X线显示跟骨长、宽、高以及Bhler角和Gissane角得到满意的恢复。Maryland足部评分系统显示优25足,良11足,可6足。优良率86%。术后早期出现切口皮缘坏死感染者2例,占总病例数4.7%。结论:切开复位跟骨钢板内固定是治疗跟骨关节内骨折的有效方法,术后早期切口并发症可以通过预防措施得到较好的控制。     

跟骨钛板内固定治疗跟骨关节内骨折26例

目的:评估切开复位跟骨钛板内固定治疗跟骨关节内骨折疗效。方法:移位跟骨关节内骨折26例27足,其中SandersII型4例4足,III型16例16足,IV型6例7足,采用外侧可延伸的L形切口入路,切开复位钛板内固定。结果:所有患者均获6~29个月随访,平均14.5个月,优20足,良5足,中1足,差1足,优良率92.6%。结论:跟骨关节内移位骨折采用切开复位钛板内固定治疗,能早期行功能锻炼,疗效满意。     

切开复位钢板内固定治疗跟骨关节内骨折32例

目的探讨切开复位钢板内固定治疗跟骨关节内骨折的疗效.方法 回顾性分析2009年1月~2011年8月治疗的32例38足跟骨骨折患者,均行跟骨外侧“L”型切口切开复位、解剖型钢板内固定治疗.结果 所有患者术后随访6~24个月,按照Mary land 评分系统评测足部功能,其中21足为优,13足为良,4足为可,优良率达89.47%.其中2足切口渗出,经换药后自愈,1足腓肠神经损伤.结论 切开复位钢板内固定是治疗跟骨关节内骨折有效的方法.     

重建钢板治疗跟骨关节内移位骨折

目的:探讨切开复位重建钢板内固定治疗跟骨关节内移位骨折的临床疗效。方法:回顾性分析2005年5月-2010年5月笔者所在医院采用切开复位重建钢板内固定治疗跟骨关节内移位骨折32例(36足)的临床资料。结果:32例获得随访,随访时间8~42个月,平均21个月。优14足,良16足,可6足,优良率83.3%。术后跟骨长度、高度、宽度及Bhlerr角和Gissane角均得到良好的恢复。骨折均愈合,愈合时间为8~18周。结论:应用重建钢板治疗新鲜跟骨关节内移位骨折,可以获得满意的临床效果,利于患者的功能恢复。     

钢板内固定治疗跟骨关节内骨折32例疗效分析

目的:探讨切开复位钢板内固定治疗跟骨关节内骨折的疗效。方法:对32例切开复位内固定治疗的跟骨关节内骨折进行随访,随访结果采用Kerr百分制评分系统评定疗效。结果:随访12~24个月,术后4个月骨折全部愈合。Kerr评定优12例,良16例,差3例,极差1例,优良率87.5%。结论:切开复位钢板内固定治疗跟骨关节内骨折是一个较好的方法,切开复位能有效恢复关节面的平整和跟骨的外形、力线。     

移位跟骨关节内骨折的手术治疗

目的：探讨应用跟骨钢板治疗跟骨关节内移位骨折的手术技巧和临床疗效。方法：对28例31足有移位的跟骨关节内骨折给予了切开复位,跟骨钢板加植骨的内固定手术治疗。根据Sanders跟骨骨折分型,Ⅱ型骨折14足,Ⅲ型骨折15足,Ⅳ型骨折2足。结果：有28足切口正常愈合,3足切口延迟愈合,无皮肤坏死和感染。患者骨折均正常愈合,所有患者都得到了随访,随访时间为8～16个月,平均12.4个月。术后功能按Maryland足部评分标准进行评分。其中,优15足,良11足,中4足,差1足,优良率84%。结论：切开复位,用跟骨钢板内固定治疗移位的跟骨关节内骨折,可以获得满意的治疗效果。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…