应用平阳霉素碘油乳剂及明胶海绵行子宫动脉栓塞治疗子宫肌瘤

目的：评估平阳霉素碘油乳剂及明胶海绵联合应用栓塞子宫动脉治疗丁宫肌瘤的临床价值。寻找理想的栓塞剂及使用方法。方法：对16例有症状的子宫肌瘤患者行双侧子宫动脉造影。根据血供情况经导管向双侧子宫动脉注入平阳霉素碘油乳剂及明胶海绵进行栓塞。结果：子宫肌瘤血供丰富多数由双侧动脉供血，栓塞后3－6个月复查B超，子宫肌瘤体积平均缩小45．8％及67．3％（P＜0．01）。月经周期恢复正常、月经量恢复正常或减少占96．7％，腹痛、贫血等症状明显改善，尿频、排尿障碍、便秘等压迫症状也有不同程度的缓解。结论：平阳霉素碘油乳剂及明胶海绵联合应用栓塞子宫动脉治疗子宫肌瘤效果好且价廉、安全，值得推广。     

子宫动脉栓塞术治疗子宫肌瘤的疗效观察

目的探讨子宫动脉栓塞术治疗子宫肌瘤的临床效果。方法采用超选择性子宫动脉栓塞术治疗8例子宫肌瘤患者。用Seldinger技术穿刺股动脉，将导管选择性插至双侧子宫动脉，经导管注入PVA颗粒或真丝线段，阻断肿瘤血供。结果经血管造影发现，子宫肌瘤瘤体血供丰富，均由双侧子宫动脉供血，栓塞双侧子宫动脉后，肿瘤血供完全阻断。治疗后随访3-6mo，临床症状明显缓解，月经量及月经周期恢复正常，肌瘤和子宫体积明显缩小。结论子宫动脉栓塞术治疗子宫肌瘤简便易行，创伤小，临床效果肯定，值得大力推广。     

选择性子宫动脉栓塞治疗子宫肌瘤的临床研究

目的探讨选择性子宫动脉栓塞治疗子宫肌瘤的临床效果及应用价值。方法采用Seldinger’s技术作选择性子宫动脉栓塞治疗15例子宫肌瘤患者。经股动脉穿刺,将导管选择性进入双侧子宫动脉,经导管注入真丝线段和明胶海绵,阻断肌瘤血供。结果经血管造影发现,子宫肌瘤血供丰富．均由双侧子宫动脉供血,栓塞双侧子宫动脉后．子宫肌瘤血供可完全阻断,治疗后6个月的随访结果表明：月经量及月经周期恢复正常,疼痛明显改善,肌瘤和子宫体积明显缩小。临床有效率86.67％。结论选择性子宫动脉栓塞治疗子宫肌瘤是一种创伤小,临床效果好的新方法。     

选择性子宫动脉栓塞治疗子宫肌瘤的临床研究

目的 观察选择性子宫动脉栓塞治疗子宫肌瘤的临床效果。方法 21例子宫肌瘤患者采用Seldinger‘s方法作选择性子宫动脉栓塞治疗，经股动脉穿刺，将导管插入子宫动脉，造影，再经导管注入真丝线段，栓塞子宫动脉。结果 造影发现子宫肌瘤血供丰富，部分肌瘤血供来自肌瘤侧子宫动脉，部分肌瘤双侧子宫动脉均参与供血。栓塞肌瘤供血侧或双侧子宫动脉后子宫肌瘤血供可完全阻断。定期随诊结果月经量及月经周期恢复正常，肌瘤和子宫体积明显缩小，临床有效率达95．24％。结论 选择性子宫动脉栓塞治疗子宫肌瘤是一种微创伤、临床效果好的新方法。     

选择性子宫动脉栓塞术治疗子宫肌瘤的临床研究

目的 研究经导管行选择性子官动脉栓塞术治疗子宫肌瘤。方法 选择27例子宫肌癯患者。采用Seldinger方法行双侧选择性子宫动脉插管。造影证实后经导管注入PVA栓塞颗粒。阻断肌瘤供血。结果，经造影证实。子宫肌瘤多由双侧子宫动脉供血。一侧为主。且血流丰富。行双侧子宫动脉栓塞后。肌瘤供血可完全墨薪。治疗后3个月、6个月随访，肿瘤体积明显缩小。月经量及月经周期恢复正常。贫血及压迫症状改善。结论 选择性子宫动脉栓塞术治疗子宫肌瘤是一种疗效显著的微创治疗新方法。     

子宫动脉栓塞术治疗子宫肌瘤

目的　探讨选择性子宫动脉栓塞术治疗子宫肌瘤的临床疗效。方法　经股动脉穿刺应用Seldinger技术引入导管鞘 ,将导管超选择性插入双侧子宫动脉 ,经导管注入PVA及明胶海绵颗粒 ,阻断肌瘤血供。结果　经子宫动脉DSA发现 ,子宫肌瘤血供丰富 ,均有双侧子宫动脉供血 ,栓塞双侧子宫动脉后 ,可以完全阻断子宫肌瘤的血供。栓塞后随访结果表明 ,肌瘤及子宫体积明显缩小 ,月经量及月经恢复正常 ,疼痛缓解 ,临床治愈。结论　子宫动脉栓塞术治疗子宫肌瘤 ,是一种创伤小、临床疗效良好、简单安全的新方法 ,其远期疗效有待进一步观察。     

选择性子宫动脉栓塞术治疗子宫肌瘤

目的探讨选择性子宫动脉栓塞术治疗子宫肌瘤的临床效果。方法97例子宫肌瘤，采用双侧子宫动脉插管栓塞治疗，术后1、3、6个月复查患者瘤体大小及临床症状改善情况。结果97例子宫肌瘤均表现为双侧子宫动脉供血，行双侧子宫动脉栓塞后，肌瘤直径明显缩小，临床症状大部分缓解，无严重并发症。结论超选择双例子宫动脉栓塞治疗子宫肌瘤是一种安全、有效的治疗方法。     

子宫动脉栓塞治疗子宫肌瘤临床疗效探讨（附32例报告）

①目的探讨子宫动脉栓塞治疗子宫肌瘤的临床应用及疗效评估。②采用导管选择性插入子宫动脉，经导管子宫动脉栓塞治疗，使用PVA颗粒(聚乙稀醇)栓塞靶动脉。③结果双侧子宫肌瘤供血动脉栓塞剂填充阻塞，术后3个月、6个月、1年随访．全部患的症状(出血，骨盆疼痛)缓解、消失，平均肌瘤缩小60％。④结论经子宫动脉栓塞子宫肌瘤疗效肯定，患临床症状改善明显，但尚有一些问题需进一步研究。     

动脉栓塞术治疗32例子宫肌瘤疗效观察

目的观察选择性子宫动脉栓塞治疗子宫肌瘤的疗效。方法行超选择性双侧子宫动脉插管栓塞治疗子宫肌瘤患者32例,术后3月、6个月随访复查患者临床症状及子宫肌瘤体积改变情况。结果32例患者子宫肌瘤均由双侧子宫动脉供血。双侧子宫动脉栓塞后,子宫肌瘤血供完全阻断,肿瘤血管消失。术后3月、6个月随访患者临床症状明显改善,肌瘤体积明显缩小。结论超选择性双侧子宫动脉栓塞治疗子宫肌瘤是一种微创、安全、疗效显著的新方法。     

选择性子宫动脉栓塞术治疗子宫肌瘤

目的探讨经皮选择性子宫动脉栓塞治疗子宫肌瘤的临床疗效相关因素.方法应用Seldinger技术,对26例子宫肌瘤患者超选双侧子宫动脉造影,经导管注入聚乙烯醇(PVA)颗粒栓塞阻断肌瘤血供.结果 26例患者血管造影显示子宫动脉明显增粗迂曲,分支增多,双侧子宫动脉供血,血供丰富,对比剂滞留染色;栓塞双侧子宫动脉后,完全阻断肌瘤血供,3～17个月随访结果表明,月经量恢复,经期缩短,疼痛缓解,超声显示肌瘤明显缩小.结论经皮子宫动脉栓塞术治疗子宫肌瘤创伤小,疗效可靠.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…