跟骨骨折治疗的疗效分析

目的:探讨手术与非手术治疗跟骨骨折的疗教和治疗方法.方法:总结5年间手术治疗的跟骨骨折38例(42足),手术方式均为钢板内固定,手术入路均为外侧"L"形扩大入路,术后不用石膏固定,2～3 d后即行不负重功能锻炼,6～8周后逐渐负重锻炼.并与40例(42足)采用非手术方法治疗的患者进行比较,所有病例随访12～36个月,平均18个月.结果:手术治疗组:优良率93%,其中Ⅰ型骨折优良率为100%,Ⅱ型骨折优良率为96%.Ⅲ型骨折优良率为75%.非手术治疗组:优良率67%,其中Ⅰ型骨折优良率为92%,Ⅱ型骨折优良率为77%.Ⅲ型骨折无优良患者.结论:对跟骨骨折治疗方式的选择应据患者的个体状况、骨折类型等综合考虑才能达到最佳效果.     

跟骨骨折手术治疗的疗效观察

目的 观察跟骨骨折的手术治疗效果.方法 对54例(58足)跟骨骨折施行切开复位内固定手术.其中SandersⅡ型16例(16足),Ⅲ型28例(30足),Ⅳ型10例(12足).手术采用跟骨外侧切口,行植骨跟骨钢板螺钉内固定.术后行踝关节功能位石膏固定3-4周后开始功能锻炼.随访5个月～7年,平均44.2个月.结果 优40足(占68.97%),良10足(占17.24%),可8足(占13.79%).优良率达86.21%.术前Bohler角10.8°,术后28.8°.结论 切开复位内固定治疗跟骨骨折复位满意,功能恢复理想,后遗症少.     

重建跟骨钢板内固定治疗Sanders Ⅱ、Ⅲ型跟骨骨折的疗效探讨

目的 评价切开复位跟骨钢板内固定治疗Sanders Ⅱ、Ⅲ型跟骨关节内骨折的效果.方法 32例(34足)跟骨骨折均采用Sanders分型,应用外侧入路,重建跟骨钢板内固定,应用美国足踝协会的后足评分系统进行结果评价,患者全部获随访.结果 随访Ⅱ型骨折22足,Ⅲ型骨折12足.术前平均B(o)hler角是6.17°,随访时平均B(o)hler角是30.0°,Gissane角术前平均为110.4°,术后平均为132.8°.81%的患者取得关节面的解剖复位或近解剖复位.优良率在Ⅱ型骨折为81.8%,Ⅲ型骨折为62.0%.总优良率为79.4%.结论 对于SandersⅡ型和Ⅲ型骨折采用切开复位重建跟骨钢板内固定治疗,近远期效果均较好.     

钛合金钢板内固定治疗Sanders Ⅲ、Ⅳ型跟骨骨折

目的评价开放复位钛合金钢板内固定治疗SandersⅢ、Ⅳ型跟骨骨折疗效。方法对32例患者46足SandersⅢ、Ⅳ型跟骨骨折采用钛合金钢板内固定。按踝-后足评分评价足部功能。结果32例患者46足跟骨骨折随访时间2～30个月。其中38足优(82.6%),6足良(13.0%),2足可(4.3%),优良率95.7%。结论钛合金钢板能够有效支撑塌陷的跟骨关节面,是一种合理的跟骨骨折内固定器。     

跗骨窦切口治疗SandersⅡ、Ⅲ型跟骨骨折

目的:探讨跗骨窦切口治疗SandersⅡ、Ⅲ型跟骨骨折的疗效。方法:采用跗骨窦切口入路治疗SandersⅡ、Ⅲ型跟骨骨折患者30例(32足)。结果:患者VAS评分2～4分(平均2.2分),AOFAS评分72～96分(平均80.3分),优12例,良14例,可4例,差0例,优良率87.5%。Bohler角、Gissane角、跟骨宽度和高度较术前明显改善(P<0.05)。4例足外侧感觉异常,术后3个月均明显改善。无术后感染、皮肤软组织坏死、内固定失败、骨不愈合及骨畸形愈合发生。术后创伤性骨关节炎:Ⅰ级13足,Ⅱ级17足,Ⅲ级2足。结论:对于SandersⅡ、Ⅲ型跟骨骨折的治疗应用跗骨窦切口是一种较好的选择,尽量恢复跟骨的解剖形态,达到较好的临床疗效。     

跟骨解剖型接骨板治疗跟骨骨折

目的 评价跟骨解剖型接骨板治疗跟骨骨折的疗效.方法 回顾性分析2006年4月至2008年6月收治的采用切开复位解剖形接骨板内固定治疗严重跟骨骨折26例(30足),按Sanders分型:Ⅱ型8足,Ⅲ型20足,Ⅳ型2足.结果 所有患者均得随访,平均随访15个月(10～20个月).根据Maryland足部评分系统评价术后疗效:优17足(56.7%),良8足(26.7%),可5足(16.6%),优良率83.4%.结论 切开复位跟骨解剖型接骨板是治疗严重跟骨骨折的一种有效可靠的方法 ,固定稳定,可早期功能锻炼,减少骨折关发症,治疗效果满意.     

锁定钢板与植骨治疗距下关节内跟骨骨折30例效果观察

目的:探讨锁定钢板与植骨治疗距下关节内跟骨骨折疗效。方法:单足跟骨距下关节面骨折30例按Sanders分型Ⅱ型8例、Ⅲ型13例、IV型9例,25例为坠落伤,5例为撞击伤,左侧跟骨骨折18例,右侧12例,采用跟骨外侧锁定钢板与关节面下支撑植骨的方法治疗关节内跟骨骨折。结果:30例均获得随访3～18个月,平均8.3个月,末次随访按Maryland足部评分系统评价术后功能:SandersⅡ型优6足,良1足,优良率87.5%,SandersⅢ型优11足,良0足,优良率84.62%,SandersIV型优6足,良1足,优良率77.78%,总优良率83.33%。结论:外侧锁定钢板联合植骨是治疗距下关节内跟骨骨折的有效方法。     

经跗骨窦切口空心螺钉内固定治疗Sanders Ⅱ、Ⅲ型跟骨骨折疗效观察

目的:探讨经跗骨窦切口空心螺钉内固定治疗SandersⅡ、Ⅲ型跟骨骨折的疗效。方法:收集38例(43足)关节内跟骨骨折患者进行随机分组,对照组21例(23足)例行外侧扩大"L"形切口切开复位钢板内固定,试验组17例(20足)行经跗骨窦切口空心螺钉内固定,记录术后并发症并得出手术优良率,术后关节功能按踝-后足评分系统(AOFAS)进行评分。结果:比较两组一般资料无明显统计学差异;比较两组术后跟骨宽度、Bohler角、Gissane角均有明显改善且有明显统计学差异;对照组组术后皮肤相关并发症发生率为17.4%,试验组组无皮肤相关并发症,两组比较有明显统计学差异;比较两组末次随访关节功能AOFAS评分及手术优良率无明显统计学差异。结论:对于SandersⅡ型和部分Ⅲ型跟骨骨折,跗骨窦切口空心螺钉内固定术切口小,术后皮肤相关并发症发生率低,是治疗关节内跟骨骨折的有效方法。     

应用跟骨解剖板治疗跟骨Sanders Ⅲ、Ⅳ型骨折的疗效分析

目的 探讨跟骨解剖板对Sanders Ⅲ、Ⅳ型跟骨骨折的疗效.方法 对20例28足Sanders Ⅲ、Ⅳ型跟骨骨折,采用跟骨解剖板加自体髂骨植骨进行复位内固定治疗.结果 本组病例随访6-38个月,平均随访时间20.5个月.按Maryland足部评分标准评价,优9足,良13足,中4足,差2足,优良率78.5%.结论 本方法治疗Sanders Ⅲ、Ⅳ型跟骨骨折复位满意,固定牢靠,术中自体髂骨植骨,术后早期关节功能锻炼,疗效肯定,是一种目前治疗Sanders Ⅲ、Ⅳ型跟骨骨折的较好方法.     

应用跟骨解剖板治疗跟骨Sanders III、IV型骨折的疗效分析

目的探讨跟骨解剖板对SandersⅢ、Ⅳ型跟骨骨折的疗效。方法对20例28足SandersⅢ、Ⅳ型跟骨骨折,采用跟骨解剖板加自体髂骨植骨进行复位内固定治疗。结果本组病例随访6-38个月,平均随访时间20.5个月。按M aryland足部评分标准评价,优9足,良13足,中4足,差2足,优良率78.5%。结论本方法治疗SandersⅢ、Ⅳ型跟骨骨折复位满意,固定牢靠,术中自体髂骨植骨,术后早期关节功能锻炼,疗效肯定,是一种目前治疗SandersⅢ、Ⅳ型跟骨骨折的较好方法。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…