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1.
To confirm the clinical therapeutic effects of acupuncture and moxibustion on Bell's palsy. Methods: 480 cases from 4 hospitals were enrolled for this study, among whom 439 cases completed the whole course of the study. The patients were randomly divided into the following 3 groups, a control group(treated with prednisone, vitamin B 1, vitamin B 12 and dibazol), an acu-moxibustion group (treated with filiform needle plus moxibustion), and a basic treatment plus acu-moxibustion group (treated with oral medicine like those in the control group plus acupuncture, and with moxibustion like in the acu-moxibustion group). The whole treatment course lasted 4 weeks. The therapeutic effects were evaluated according to the symptoms and signs, House-Brackmann grading scale and facial disability indexes(FDI). Results: All the 4 centers (hospitals) completed this study well, with no statistically significant difference found among the 4 centers in therapeutic effects. The patients with different conditions were well distributed in the 3 groups, thus the basic general data were comparable (P〉0.05). The therapeutic effects of the two treatment groups were better than the control group (respectively P〈0.05 and P〈0.01), and it was the best in the acu-moxibustion group (P〈0.01). Conclusion: Acupuncture and moxibustion may exert definite therapeutic effects on Bell's palsy, better than that of the basic treatment group or the basic treatment plus acu-moxibustion group. 相似文献
2.
《中医杂志(英文版)》2006,(1)
To confirm the clinical therapeutic effects of acupuncture and moxibustion on Bell's palsy.Methods:480 cases from 4 hospitals were enrolled for this study,among whom 439 cases completed thewhole course of the study.The patients were randomly divided into the following 3 groups,a controlgroup(treated with prednisone,vitamin Bl,vitamin B_(12)and dibazol),an acu-moxibustion group(treatedwith filiform needle plus moxibustion),and a basic treatment plus acu-moxibustion group(treated withoral medicine like those in the control group plus acupuncture,and with moxibustion like in theacu-moxibustion group).The whole treatment course lasted 4 weeks.The therapeutic effects wereevaluated according to the symptoms and signs,House-Brackmann grading scale and facial disabilityindexes(FDI).Results:All the 4 centers(hospitals)completed this study well,with no statisticallysignificant difference found among the 4 centers in therapeutic effects.The patients with differentconditions were well distributed in the 3 groups,thus the basic general,data were comparable(P>0.05).The therapeutic effects of the two treatment groups were better than the control group(respectivelyP<0.05 and P<0.01),and it was the best in the acu-moxibustion group(P<0.01).Conclusion:Acupuncture and moxibustion may exert definite therapeutic effects on Bell's palsy,better than that ofthe basic treatment group or the basic treatment plus acu-moxibustion group. 相似文献
3.
OBJECTIVE: There are no convenient techniques to evaluate the degree of facial nerve injury during a course of acupuncture treatment for Bell's palsy. Our previous studies found that observing the electrical response of specific facial muscles provided reasonable correlation with the prognosis of electroacupuncture treatment. Hence, we used the new method to evaluate the degree of facial nerve injury in patients with Bell's palsy in comparison with the House-Brackmann scale. The relationship between therapeutic effects and prognosis was analyzed to explore an objective method for evaluating Bell's palsy. METHODS: The facial nerve function of 68 patients with Bell's palsy was assessed with both electrical response grading and the House-Brackmann scale before treatment. Then differences in evaluation results of the two methods were compared. All enrolled patients received electroacupuncture treatment with disperse-dense wave at 1/100 Hz for 4 weeks. After treatment, correlation analysis was conducted to find the relationship between electrical response and therapeutic effects or prognosis. RESULTS: Checking consistency between electrical response grading and House-Brackmann scale: Kappa value 0.028 (P = 0.578). Correlation analysis: the two methods were correlated with the prognosis, and electrical response grading (rER = 0.789) was better than the House-Brackmann scale (rHB = 0.423). CONCLUSION: Electrical response grading is superior to the House-Brackmann scale in efficacy and reliability, and can conveniently assess the degree of facial nerve injury. The House-Brackmann scale is suitable for the patients with mild facial nerve injury, but its evaluation quality for severe facial nerve injury is poor. 相似文献
4.
Objective: To study the curative effect of acupoint stimulation on the earthquake-caused post-traumatic stress disorder (PTSD). Methods: The 91 PTSD patients in Wenchuan hit by a strong earthquake were randomly divided into a control group of 24 cases treated by the cognitive-behavior therapy, and a treatment group of 67 cases treated by both cognitive-behavior therapy and acupoint stimulation. The scores were evaluated according to Chinese version of the incident effect scale revised (IES-R) and the self-compiled questionnaire for the major post-traumatic psychological condition, and the curative effect was compared between the two groups. Results: The total scores of IES-R, the scores of all factors and the total scores of the questionnaire in the two groups after treatment were much lower than those before treatment (P<0.01). The comparison of reduction in the factor scores between the two groups showed that the curative effect in the treatment group was better that ofin the control group. Conclusion: The acupoint stimulation is effective for the PTSD patients, with better results than that of cognitive-behavior therapy used alone 相似文献
5.
Objective:To observe the clinical efficacy and adverse reactions of Paroxetine combined with electro-acupuncture (EA) in treating depression.Methods:Forty-two patients with depression were randomly assigned to the observation group (22 patients) treated with EA combined with Paroxetine,and the control group (20 patients) treated with Paroxetine alone,and the therapeutic course for both groups was 6 weeks.The therapeutic efficacy and adverse reactions were evaluated with scores by Hamilton depression scale (HAMD) and treatment emergent symptoms scale (TESS), respectively.Results:HAMD scores determined at the end of the 1st,2nd,4th,and 6th week of the treatment course were significantly lower in the observation group than those in the control group (P<0.05).The significant improvement rate evaluated at the end of the 6-week treatment was remarkably higher in the observation group than that in the control group (72.7% vs 40.0%).No significant difference of TESS scores was found between the two groups.Conclusion:EA combined with Paroxetine has better clinical efficacy than that of Paroxetine alone,with milder adverse reaction and quicker initiation of effect. 相似文献
6.
Effectiveness of Bushen Huoxue Granule (补肾活血颗粒) on 5-Serotonin and Norepinephrine in the Brain of Parkinson''s Disease Patients with Depressive State 下载免费PDF全文
Objective:To observe the clinical curative effect of Chinese medicine Bushen Huoxue Granule(补肾活血颗粒,BHG) on Parkinson's disease(PD) patients with depressive state.Methods:Sixty-two PD patients with depressive state were randomly assigned to two groups by using a random number table,31 in each group.Madopar was given to all as the conventional treatment.The fluoxetine hydrochloride dispersible tablet was given to the patients in the control group and BHG was given to those in the treatment group.The therapeutic course for all was 12 weeks.Before and after treatment,Hamilton depression rating scale(HAMD) was applied to judge the curative effect,and the changes of cerebral neurotransmitters levels in the brain of patients were detected by encephalofluctuograph technique.Results:The scores of HAMD in the two groups were decreased markedly after 12-week treatment.It was lower in the treatment group than that in the control group with significant difference(P〈0.01).The contents of norepinephrine(NE) and 5-serotonin(5-HT) in the PD patients were obviously lower than normal value.There was no significant difference between the two groups before treatment(P〉0.05).The contents of NE and 5-HT were all increased in the two groups after treatment(P〈0.05),with significant differences between the two groups(P〈0.01).Conclusion:BHG could increase the contents of NE and 5-HT in PD patients' brain to improve the depressive state of PD patients. 相似文献
7.
Hongwei Zhang Liyou Wei Zhenyu Zhang Shuzheng Liu Gang Zhao Jing Zhang Yanling Hu 《中医杂志(英文版)》2013,(1):70-73
OBJECTIVE: To investigate the effect of the periplaneta americana extract on the intestinal mucosal barrier and prognostic implications in patients with sepsis. METHODS: Sixty and six patients with sepsis were assigned randomly to treatment group (32 cases) and control group (32 cases). The extractfrom periplaneta americana plus conventional medication for sepsis was administered to the treatment group, while the control group only received conventional treatment. The gastrointestinal function scores and acute physiology and chronic health evaluation II (APACHEⅡ) scores of all subjects were documented at baseline, at days 1, 3 and 7 after treatment respectively and their blood endotoxin was tested at the same time points as well.The incidence of death was recorded for both groups throughout the trial. RESULTS: At days 3 and 7 after treatment, gastroin-testinal function score, APACHE II, and endotoxin level in treatment group wasbetter than that in control group and the difference between them was significant (both P<0.05). Although the incidence of death in treatment group was less than that in control group, the difference between the two groups was not significant (P> 0.05). CONCLUSION: The extract of periplaneta americana had protective effect on intestinal mucosal barrier and could improve the condition and prognosis in patients with sepsis. 相似文献
8.
Objective To objectively evaluate the clinical therapeutic effect of Tongfengkang (TFK) in treating acute gouty arthritis. Methods: Adopting randomized single blinded controlled trial, the 40 patients were equally divided into two groups. The tested group was treated with TFK, the control group was treated with indomethacin and allopurinol, the therapeutic course for both groups was 10 days. Results: The clinical cure rate in the tested group and the control group was 30% and 35% respectively, and the total effective rate 90% and 95% respectively, with no significant difference between the two groups (P>0.05).The scores of blood uric acid and symptom significantly lowered in both groups after treatment (P <0.01), but showed no significant difference between them (P>0.05). Adverse reaction to the treatment was shown in 3 patients in the control group. Conclusion: The therapeutic effect of TFK is similar to that of indomethacin plus allopurinol but with less adverse reaction, it is an effective and safe re 相似文献
9.
A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris by auricular therapy combined with optimized Yinxieling Formula (银屑灵优化方) 下载免费PDF全文
Objective:To explore the therapeutic effect of auricular therapy combined with optimized Yinxieling Formula(银屑灵优化方) on psoriasis vulgaris.Methods:A randomized controlled single-blind clinical trial on 84 outpatients with psoriasis vulgaris was conducted.The patients were randomized to a treatment group(43 cases treated by auricular therapy combined with optimized Yinxieling Formula) and a control group (41 cases treated by optimized Yinxieling Formula alone) according to a random number generated by SPSS 17.0 software.The treatment duration for both groups was 8 weeks.The therapeutic effect was comprehensively measured by the primary outcome measure[Psoriasis Area and Severity Index(PASI) reduction rate]and the secondary outcome measure[PASI,Visual Analogue Scale(VAS),Dermatology Life Quality Index(DLQI), Self-rating Depression Scale(SDS),and Self-rating Anxiety Scale(SAS)].The outcomes of both groups were obtained and compared before and after the intervention.Results:The PASI reduction rate in the treatment group was 74.4%(32/43),which was higher than that in the control group(36.6%,15/41,P<0.01).The PASI scores decreased in both groups after treatment and was lower in the treatment group compared with the control group (P<0.01).With stratified analysis,there were significant differences between the PASI scores in the following subgroups:age 18-30,baseline PASI>10 and stable stage(P<0.05).DLQI decreased in both groups on some categories after treatment,but there were no significant differences between the two groups in SDS,SAS and VAS(P>0.05).No obvious adverse reactions were found in either group.Conclusion:The therapeutic effect of auricular therapy combined with Optimized Yinxieling Formula was superior to Optimized Yinxieling Formula alone with no obvious adverse reaction. 相似文献
10.
Objective: To observe the intervention effects of Tiaobu Xinshen Recipe(调补心肾方, TXR) on patients with mild cognitive impairment caused by Alzheimer's disease(MCI-AD). Methods: Totally 88 MCI-AD patients with syndrome of Xin(Heart) and Shen(Kidney) deficiency were assigned to the experimental group(47 cases, treated with TXR) and the control group(41 cases, treated with donepezil hydrochloride) using a random number table. Final recruited qualified patients were 44 cases in the experimental group and 39 cases in the control group. The therapeutic course was 12 weeks. Neuropsychological scales [mini mental state examination(MMSE) and Montreal cognitive assessment(MoCA)], and Chinese medicine(CM) dementia syndromes scales were performed in all patients, and results were compared between groups or intra-group before and after treatment. Results: MMSE and Mo CA scores of the two groups were increased after treatment compared with those before treatment(P0.05). But there was no statistical difference in MMSE or MOCA scores after treatment between the two groups(P0.05). CM dementia syndrome score was significantly decreased after treatment in the experimental group compared with the control group(P0.01). Visual spatial and executive function scores and delayed recall scores of the two groups were increased compared with those before treatment(P0.01). Conclusion: TXR could effectively improve cognitive impairment of MCI-AD patients with syndrome of Xin and Shen deficiency. 相似文献
11.
Shahidullah M Haque A Islam MR Rizvi AN Sultana N Mia BA Hussain MA 《Mymensingh medical journal : MMJ》2011,20(4):605-613
The antiviral drug acyclovir or its analogue, valacyclovir, has been applied in various trials on Bell's palsy with inconsistent results. We compared the therapeutic effect of famciclovir plus prednisolone with prednisolone alone, in patients with Bell's palsy. In a randomized, prospective trial, 68 patients were randomized to treatment with famciclovir and prednisolone (34 patients) or prednisolone alone (34 patients). All patients underwent supportive therapy. Severity of Bell's palsy was evaluated using the House-Brackmann scale (HBS). Follow-up was done after 1 week, 1 month and 3 months, with complete recovery defined as House-Brackmann grade I. The analysis revealed that recovery rates at month 1 and 3 were significantly higher in combination group than that of prednisolone only group (94.1% vs. 61.8% and 97.1% vs. 74.5% respectively). Again recovery from mild to moderate (HBS-II, III, IV) Bell's palsy occurred completely at month 3 and that of severe (HBS-V, VI) Bell's palsy was two-third of the patients. Again in severe Bell's palsy combination treatment increased the chance of complete recovery more than 10-fold than that of steroid only. The study results suggest that better outcome for Bell's palsy patients occurred if they were treated with prednisolone and famciclovir combination instead of prednisolone alone. In fact a considerable number of patients were benefited from additional antiviral therapy with famciclovir. 相似文献
12.
Bell's palsy is a common neurological problem causing considerable loss of self-esteem among patients. A prospective observational study was conducted to determine the short-term outcome of Bell's palsy at 1 month and 2 months after the onset and the relationship between these outcomes with facial nerve degeneration. We also determined if gender, age, diabetes, systolic and diastolic blood pressure influence the severity of facial nerve degeneration and the clinical outcome at 2 months after the onset. After clinically grading the newly diagnosed unilateral Bell's palsy patients using the House-Brackmann facial nerve grading system, nerve conduction studies of the facial nerve were done to determine the severity of facial nerve degeneration. The recovery of the facial paralysis was clinically graded again at the end of 1 month and 2 months from the onset. A total of 37 patients were recruited. There was a strong positive correlation between facial nerve degeneration and the clinical outcome of Bell's palsy at 1 month (r = 0.794; p < 0.0005) and 2 months (r = 0.732; p < 0.0005) after the onset. There was no significant correlation between either the facial nerve degeneration or the clinical outcome at 2 months with the patients' age (p = 0.288 and p = 0.799 respectively), systolic blood pressure (p = 0.425 and p = 0.933 respectively) or diastolic blood pressure (p = 0.243 and p = 0.579 respectively). Neither the severity of facial nerve degeneration nor the clinical outcome at 2 months were significantly different between male and female patients (p = 0.460 and p = 0.725 respectively) or diabetic and non-diabetic patients (p = 0.655 and p = 0.655 respectively). 相似文献
13.
目的 观察运用火针治疗中枢性面瘫的临床疗效,并探讨其作用机制。方法 按照随机数字表法随机选取108例中枢性面瘫患者,将其分为对照组(普通针刺疗法)和治疗组(火针疗法),每组54例。比较两组患者临床疗效,治疗前后分别采用修订的面神经功能量表(modified house-brackmann,MHBN)和面部残疾指数(face disability index,FDI)评价面部神经功能。结果 两组临床疗效的分布比较,差异具有统计学意义(P<0.05)。两组患者治疗后MHBN评分均较治疗前显著提高(P<0.05),且治疗组治疗后MHBN评分提高程度高于对照组(P<0.05)。两组患者治疗后各项评分较治疗前均明显提高(P<0.05),且治疗组在进食困难、喝饮料困难、流泪困难、刷牙或漱口困难的改善程度上优于对照组(P<0.05)。结论 与普通针刺法相比,火针法能更有效地改善中枢性面瘫后面部的感觉及运动功能,更有利于面神经功能的恢复,尤其适用于难治性面瘫患者。 相似文献
14.
Objective: To compare the clinical effects of thick-needle therapy (TNT) and acupuncture therapy(AT) on patients with Bell''s palsy (BP) at the recovery stage. Methods: A total of 146 eligible participants from 3 hospitals in China were randomized into the TNT group (73 cases) and the AT group (73 cases) using a central randomization. Both groups received Western medicine thrice a day for 4 weeks. Moreover, patients in the TNT group received subcutaneous insertion of a thick needle into Shendao (GV 11) acupoint, while patients in the AT group received AT at acupoints of Cuanzhu (BL 2), Yangbai (GB 14), Dicang (ST 4), Xiaguan (ST 7), Jiache (ST 6), Yingxiang (LI 20) and Hegu (LI 4), 4 times a week, for 4 weeks. Both groups received 2 follow-up visits, which were arranged at 1 month and 3 months after treatment, respectively. The primary outcome measure was House-Brackmann Facial Nerve Grading System (HBFNGS) grade. And the clinical recovery rates of both groups were evaluated according to the HBFNGS grades after treatment. The secondary outcome measures included the facial disability index (FDI) and electroneurogram (EnoG). The adverse events were observed and recorded in both groups. Results: Three cases withdrew from the trial, 2 in the TNT group and 1 in the AT group. There was no significant difference in the clinical recovery rates between the TNT and AT groups after 4-week treatment [40.85% (29/71) vs. 34.72% (25/72), P>0.05]. At the 2nd follow-up visit, more patients in the TNT group showed reduced HBFNGS grades than those in the AT group (P<0.01). No significant difference was observed between the two groups in FDI score, EnoG latency and maximum amplitude ratio at all time points (all P>0.05). Conclusion: The clinical effect of TNT was equivalent to that of AT in patients with BP at recovery stage, while the post-treatment effect of TNT was superior to that of AT. (Registration No. ChiCTR-INR-16008409) 相似文献
15.
目的观察中药敷贴综合治疗特发性面神经麻痹的疗效。方法采用随机对照研究,将首次诊断为特发性面神经麻痹的患者随机分为2组。治疗组30例用中药敷贴加基础治疗;对照组30例用强的松加基础治疗。基础治疗包括多种维生素治疗、针灸、理疗等。结果治疗组总有效率与对照组比较,无统计学差异。面瘫恢复时间2组亦无明显差异。结论中药敷贴治疗特发性面神经麻痹疗效好,安全性高。 相似文献
16.
目的 探讨星状神经节阻滞配合滞针牵拉疗法在顽固性面瘫患者中的应用效果。方法 选取2017年3月至2020年7月西安市阎良区中医医院收治的68例顽固性面瘫患者,按照治疗方法不同分为研究组与对照组(各34例),对照组患者给予星状神经节阻滞治疗,研究组患者给予星状神经节阻滞配合滞针牵拉疗法治疗,比较两组患者面神经功能(House-Brackmann,H-B)分级、H-B积分、面部残疾指数(FDI)量表积分、面神经电图评价及总有效率。结果 治疗后,研究组患者H-B分级与积分、FDI量表积分、眼轮与口轮匝肌波幅等观察指标均显著高于对照组(P<0.05),研究组总有效率(94.12%),显著优于对照组(80.43%,P<0.05)。结论 星状神经节阻滞配合滞针牵拉疗法具有显著加速顽固性面瘫患者的面神经功能的恢复,提高治愈率,有效改善患者的临床症状,提高治疗依从性等优势。 相似文献
17.
目的初步验证贺氏火针治疗特发性面神经麻痹的临床疗效。方法采用随机临床对照研究方法,将100例患者分为对照组和治疗组,各50例。对照组为毫针针刺,治疗组在对照组基础上加贺氏火针疗法。主要评价指标面部残疾指数(FDI),次要评价指标Sunnybrook面神经评分系统、House-Brackmann分级标准。分别对2组在入组后、4周末、8周末进行疗效评价。结果与对照组比较,治疗组躯体功能评分、Sunnybrook面神经评分在第4、8周末明显提高(P0.05),而社会功能评分在第8周末有明显降低(P0.05);经过4周的治疗,治疗组有54%完全恢复(功能正常),优于对照组的38%(P0.05);治疗8周末,治疗组有86%完全恢复(功能正常)优于对照组的64%(P0.05)。结论贺氏火针能够有效改善患者面神经功能评分,促进面神经功能的恢复,提高生活质量。 相似文献
18.
目的 运用灵龟八法配合面瘫针治疗Bell麻痹患者,探讨该法治疗Bell麻痹的有效性及其机理.方法 随机分组的4组Bell麻痹患者,A组:灵龟八法配合面瘫针组、B组:面瘫针组、C组:常规针刺组、D组:西药组.治疗≤2个疗程,每个疗程4周,治疗前及发病2,4,8周后进行House-Brackmann面神经分级与症状积分、瞬目反射(BR)、肌电图(EMG)、神经电图(ENoG)及红外热像测定.结果 根据House-Brackmann面神经分级与症状积分评定疗效,4组有效率比较A组疗效最好,疗程最短(P<0.05).各项神经电生理检查及红外热像结果在治疗后变化中A组变化差异均最显著(P<0.05).结论 灵龟八法配合面瘫针治疗Bell麻痹在疗效及疗程方面均有较大的优势.且该疗法取穴简便、安全,使患者易以接受,值得临床推广. 相似文献