肝炎肝硬化螺旋CT门静脉造影扫描延迟时间的合理选择

目的　应用时间—密度曲线选择正常人和肝炎肝硬化患者螺旋 CT门静脉造影的合理扫描延迟时间 .方法　 2 0例正常人和 1 8例肝炎后肝硬化患者于第一肝门水平门静脉主干分叉以下 1 0 mm处行同层动态增强扫描 .造影剂量 1 .5m L· kg-1 ,注射速率 3 m L· s-1 ,经外周静脉注射造影剂后1 5 s开始扫描 ,以后每隔 5 s扫描 1次 ,持续至 1 2 0 s.分别测量同一层面门静脉、肝脏的 CT值 ,并计算各点门静脉与肝脏的密度差 (P- L) ,描绘时间 -密度曲线 .结果　正常组与肝硬化组门静脉平均强化峰值分别为 (1 81± 34) Hu,(1 59± 2 9)Hu(P<0 .0 5) ,峰值到达时间分别为 (54± 7) s,(65± 9) s(P<0 .0 5) .肝脏平均强化峰值分别为 (1 1 8± 1 9) Hu,(96±1 3) Hu(P<0 .0 5) ,峰值到达时间分别为 (64± 9) s,(75±1 0 ) s(P<0 .0 5) .门静脉和肝脏密度差最大值两组分别为(9 0± 2 8) Hu,(73± 1 6) Hu(P<0 .0 5) ,其达到最大密度差时间分别为 (50± 7) s,(65± 3) s(P<0 .0 1 ) .结论　行肝脏螺旋 CT门静脉造影成像显示肝内门静脉分支 ,造影剂量为 1 .5m L· kg-1 ,注射速率为 3m L· s-1 ,正常人最佳扫描延迟时间为 40 s,肝炎后肝硬化患者最佳扫描延迟时间为 50 s     

螺旋CT双期扫描对诊断小肝癌的应用价值

目的　评价螺旋CT扫描的动脉期、静脉期以及双期联合应用对小肝癌的诊断评价。方法　对 2 3例拟诊小肝癌患者行螺旋CT动、静脉双期增强扫描 ,增强动脉期于造影剂注射后 3 0s开始扫描 ,静脉期于 60～ 70s开始扫描 ,造影剂注射速率为 3 .0ml/s ,用量 80～ 10 0ml。结果　 2 3例小肝癌共发现 2 8个结节病灶。平扫、动脉期、静脉期、动静脉双期的检出率分别为 75 .0 0 %、93 .86%、82 .14 %、96.43 % ,动脉期和动静脉双期的检出率较平扫和静脉期高 (P <0 .0 5 ) ,动脉期和动静脉双期间 ,平扫和静脉期间比较差异无显著性 (P均 >0 .0 5 )。 71.43 % (2 0 /2 8)的小肝癌动脉期呈均匀高密度影 ,与同期肝组织比较 ,CT值增加 2 4.9± 13 .8Hu ;17.86% (5 /2 8)呈不均匀高密度影。 82 .14 % (2 3 /2 8)静脉期呈低密度影 ,与同期肝组织比较 ,CT值减少 13 .8± 8.5Hu ;17.86% (5 /2 8)为等密度影。双期扫描的定性准确率为 96.43 %。结论　螺旋CT动静脉双期扫描对小肝癌诊断有很高的敏感性和特异性。     

多层螺旋CT双期增强扫描对胰头—壶腹区肿瘤的诊断价值

目的评价多层螺旋CT双期增强扫描对胰头—壶腹区肿瘤的诊断价值。方法对29例经手术、病理证实的胰头—壶腹区肿瘤的螺旋CT平扫及双期增强扫描进行回顾性分析。结果9例胰头癌胰腺期胰腺—肿瘤密度差为(67±14)Hu,高于实质期的(36±19)Hu,差异有统计学意义(P<0.01);7例胰头段胆总管癌胰腺期肿瘤—胰腺密度差为(35±21)Hu,低于实质期的(57±18)Hu,差异有统计学意义(P<0.05);13例壶腹癌胰腺期胰腺—肿瘤密度差为(35±18)Hu,实质期为(30±17)Hu,差异无统计学意义(P>0.05)。结论多层螺旋CT双期增强扫描在胰头—壶腹区肿瘤的诊断与鉴别诊断中具有重要价值。     

多层螺旋CT双期扫描技术在胰腺肿瘤中的应用

目的 探讨多层螺旋CT双期扫描技术对胰腺肿瘤检出,诊断和进行可切除性评估的意义.方法 对38例胰腺肿瘤患者行胰腺平扫、胰腺期和肝脏期扫描,对各时相的正常胰腺和肿瘤组织进行CT值测量,计算各时相两者的CT值差别,观察胰周血管和其他变化,作可切除性评估.结果 胰腺肿瘤双期扫描各时相的CT值差分别为平扫(6±3)Hu,胰腺期(43±18)Hu,肝脏期(23±16)Hu,胰腺期差别最大,对胰腺肿瘤的检出和诊断有意义.观察胰周小静脉扩张和其他变化进行手术可切除性评估.结论 多层螺旋CT的双期扫描技术优于普通螺旋CT,对胰腺肿瘤的检出和诊断及可切除性评估有重要意义.     

螺旋CT薄层三期增强扫描及CTHA在诊断小肝癌中的价值

目的 :分析小肝癌 (SHCC)螺旋 CT薄层三期增强扫描 (Triple- phase helical CT THCT)及肝动脉 CT造影 (CTHA)表现特征 ,评价其应用价值。方法 :研究分析 16例经肝穿细胞学检查或临床证实 SHCC患者 CT图像 ,采用高质量扫描模式 ,扫描参数为 :层厚 5 m m,螺距 5 mm,增强三期扫描分别为注射对比剂 2 0 s～ 2 5 s动脉期 ,4 5 s～6 0 s门脉期扫描 ,2 min～ 3min延迟期扫描 ,130 k V,2 70 m A～ 30 0 m A,高压注射器单相注射 ,非离子型对比剂注射速率 2 .5 ml/ s～ 3ml/ s,剂量为 1.2 ml/ kg～ 1.5 m l/ kg,CTHA采用 Seldinger法插管 ,将导管插入肝固有动脉 ,然后将患者搬入 CT室进行造影 CT,造影剂为 2 0 %非离子对比剂 10 ml～ 15 ml,以双盲法分析其各期及 CTHA表现。结果 :16例 SHCC中检查出 19个病灶 ,其中 12例在三期扫描上为典型表现 ,即动脉期为高密度 ,门静脉期和延迟期为低密度或等低密度 ,4例为非典型表现 ,CTHA 14例呈高密度 ,2例为低密度 ;后经碘油 CT证实。结论 :大多数 SHCC在三期扫描呈典型表现 ,动脉期是 SHCC定性诊断的关键 ,THCT应用可显著增强 SHCC检出率 ,CTHA可进一步提供血动力学特征 ,两者相结合可大大提高 SHCC诊断率和鉴别诊断能力。     

螺旋CT双期增强扫描在小胰腺癌诊断中的应用

目的　研究螺旋ＣＴ胰腺期、门脉期双期增强扫描在小胰腺癌早期诊断和正确分期中的作用。方法　对 14例小胰腺癌患者行螺旋ＣＴ双期增强扫描 ,扫描延迟时间分别为30ｓ和 6 5ｓ,对比剂用量 10 0ｍｌ,注射速度 3ｍｌ/ｓ。观察并比较正常胰腺及肿瘤在两期的增强情况。根据ＣＴ征象对肿瘤可切除性进行评价 ,并与手术结果比较。结果　肿瘤 胰腺对比胰腺期和门脉期分别为 (4 7 0 8± 2 0 39)ＨＵ和 (2 8 77±16 2 3)ＨＵ(Ｐ <0 0 1)。 14例肿瘤中 ,术前认为可以切除 11例 ,术中切除 9例。结论　螺旋ＣＴ双期增强扫描能更清晰地显示小胰腺癌 ,…     

多层螺旋CT三期增强扫描对小肝癌的诊断

目的:分析小肝癌在螺旋CT三期(动脉期、门脉期和延迟期)增强扫描的表现,比较各期的病灶检出率,提高小肝癌的诊断水平。方法:18例小肝癌分别行多层螺旋CT平扫及三期增强扫描,扫描时间分别为动脉期25s、门脉期70s、延迟期5m in,用高压注射器经肘静脉注射,速率为3 m l/s,剂量为1.5 m l/kg。结果:共发现20个病灶,动脉期、门脉期和延迟期的检出率分别为80%,60%和65%。动脉期的敏感性高于门脉期和延迟期。三期联合后检出率明显增加达95%。结论:多层螺旋CT三期增强扫描能反映出小肝癌血供特点和表现,使其早期诊断成为可能。     

螺旋CT胰腺期增强扫描在胰腺癌诊断和分期中的价值

目的:研究螺旋CT胰腺期增强扫描在胰腺癌诊断和分期中的价值。方法:对34例胰腺癌患者行螺旋CT胰腺期和门脉期双期增强扫描,扫描延迟时间分别为30s和65s,对比剂用量100ml,注射速度3ml/s。观察并比较正常胰腺与肿瘤在两期增强中的对比情况,以及胰腺周围血管、组织和器官的受侵情况。根据CT征象对肿瘤可切除性进行评价,并与手术结果比较。结果:肿瘤—胰腺对比在胰腺期34例中对比明显32例,对比较明显2例;门脉期对比明显10例,对比较明显14例,对比不明显10例。胰腺期扫描能清晰显示胰周血管,其中胰周血管中断6例,包绕4例,部分包绕3例。术前认为可以切除21例,术中切除20例。结论:螺旋CT胰腺期增强扫描比门脉期增强扫描更清晰地显示胰腺癌,并有利于胰腺癌分期和可切除性的判断。     

螺旋CT双期扫描在小胰腺癌诊断中的价值

目的 :探讨螺旋CT双期扫描技术及其在小胰腺癌诊断中的价值。方法 :对12例小胰腺癌患者进行双期螺旋扫描 ,扫描延迟时间分别为30s和70s ,对比剂用量100ml,注射速度3ml/s ,观察比较正常胰腺和肿瘤在两期增强情况 ,根据CT表现对肿瘤可切除性进行术前评估 ,并与手术结果比较。结果 :胰腺期和门脉期的密度差分别为(43±9.0)HU和 (21±14)HU ,P<0.01,12例小胰腺癌术前认为可切除9例 ,与手术结果相符。结论 :胰腺期胰腺与肿瘤密度对比较门脉期更显著 ,螺旋CT双期扫描有利于小胰腺癌检出和正确术前评估。     

螺旋CT双期增强扫描在胰腺癌诊断中的应用及分析

目的:探讨螺旋CT双期增强扫描在诊断胰腺癌中的应用价值和临床意义。方法:26例胰腺癌患者先行CT平扫,再用高压注射器以3 ml/s的速率团注造影剂(非离子型)100ml分别行胰腺期(注入后30秒)与门脉期(注入后65秒)增强扫描,测定并计算2期中正常胰腺与肿瘤的平均CT值及正常胰腺与肿瘤在2期平均CT值的差值。结果:26例中肿块位于胰头颈部17例,钩突部5例,体部2例,尾部2例。直径小于2cm肿块4例。正常胰腺与肿瘤间的强化CT差值在胰腺期显著大于门脉期(P0.01),肿瘤在增强胰腺期显示更清晰,为相对低密度,胰周动脉和胰周静脉分别在胰腺期、门脉期显示满意。结论:螺旋CT双期增强扫描对胰腺癌的诊断和临床治疗方案的制定具有极大的应用价值及意义。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.