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1.
吉杉  汪晓军 《北京医学》2016,(9):945-947
目的 探讨健康人、肝硬化代偿期及失代偿期患者面部区位点的色度值及关系.方法 应用DS-01A中医四诊仪实测肝硬化代偿期患者198例,肝硬化失代偿期患者164例,健康人134例,检测受试者面部整体、额区、鼻区、唇区、左右脸颊区、眼区各部位的HSV值[H(色度)、S(鲜艳度)、V(明度)],对所得数据进行比较分析.结果 健康人群和肝硬化(代偿期、失代偿期)患者面部色部区位点色度值的差异有统计学意义(P<0.05).肝硬化患者面部整体、颊区、眼区区位点H值、V值较健康人群低.肝硬化失代偿期患者面部整体、颊区、眼区区位点S值较代偿期患者高.结论 健康人群和肝硬化患者不同脏腑面部色部区位点色度值有明显差异.肝硬化患者颊区、眼区及面部整体的颜色较健康人晦暗,且失代偿期患者较代偿期患者面色更晦暗.  相似文献   

2.
目的:观察健康人群和亚健康状态人群面部不同点位的光谱色度情况,为健康状态的评价提供客观依据。方法:用"健康状态评价问卷"H20V2009对470名无明确急慢性疾病者进行健康状态评估,根据主观量表得分分为健康状态、亚健康状态,并根据中医辨证对亚健康进行五脏定位分析。采用CM-2600D分光测色仪,观测额部、眉间部、鼻部、下颏、左颧部、右颧部、左眼胞及右眼胞8处的L、a、b、C值以及400~700nm不同波长段的面色反射率。结果:与健康组比较,亚健康组整体面部色度特征L值偏高(P〈0.05),a、b、C值偏低(P〈0.05),提示亚健康组面色较健康组浅淡、色度偏低;在400~560nm段波长反射率,亚健康组偏高(P〈0.05),显示亚健康组面色偏青;亚健康组面部额部、眉间、鼻部a、b和C值差异明显。亚健康五脏分型各组L值较健康组升高(P〈0.05);亚健康不同脏腑辨证组间色度值存在一定差异,其中肺型与其他各型差异最显著,a、b和C值较其他各型降低;亚健康不同脏腑辨证组间光谱反射率比较,肺型在400~520nm、脾型在420~600nm段与其他各组差异有统计学意义(P〈0.05),肺型低于其他脏型,脾型高于其他脏型。结论:亚健康状态不同五脏辨证分型者的面部不同点位光谱色度不同,可以为健康的评价提供客观依据。  相似文献   

3.
目的 探讨慢性病毒性肝炎不同G、S分期与门、脾静脉血流动力学变化的关系.方法根据肝穿刺活检结果将348例慢性病毒性肝炎患者分为无肝纤维化(S0)~肝硬化(S4)5期,按炎症分级为G1~G4 4级.比较慢肝患者不同G/S分期之间门、脾静脉血流的差异.结果不同G分期之间Drpv、RPVFV差异有显著性,且随分期增高值明显增大.不同S分期之间Dpv、Drpv、Dspv、VsSPV、VmSPV差异有显著性.S1~3分期内Dpv、Drpv随S分期增高而增宽;S1~4分期内Dspv随S分期增高而增宽;S0~4分期内VsSPV、VmSPV随S分期增高而降低.慢肝不同程度之间Drpv、Dspv、RPVFV差异有显著性,且随慢肝程度越重数值越大.VsPV与VsRPV、VsLPV、VsSPV的相关系数r分别为0.496、0.377、0.442.PVFV与RPVFV、LPVFV、SPVFV的相关系数r分别为0.482、0.334、0.370.结论门、脾静脉血流动力学改变与慢性肝炎不同G、S分期相关.动态测定门、脾静脉速度及血流量可以反映慢肝患者肝纤维化的程度.  相似文献   

4.
目的:探讨病毒性肝病(VH)生化检验指标变化特点及诊断价值.方法:选取该院2014年8月至2016年8月间收治的64例VH患者作为观察组;选取同时段入院进行健康体检的健康人64例作为对照组,对比两组受检者各项生化指标差异,判定病毒性肝炎的诊断结果.结果:经检查显示观察组AS、TBil、CHE、ALT等指标均明显高于健康受检者(P<0.05),同时观察组上述指标的阳性率明显高于对照组(P<0.05);急慢性肝炎患者的PA值、慢性肝炎和肝癌患者的ADA值以及肝癌患者的LAP值均显著高于其他类患者,数据差异显著,P<0.05.结论:在病毒性肝病患者的临床诊断中,肝功能指标AS、TBil、CHE、ALT等异于健康人群,而且肝功能指标阳性率显著升高.通过生化检验,能够准确判断患者肝病类型及预后,值得椎广应用.  相似文献   

5.
目的:测定总胆红素(TB)、总胆汁酸(TBA)、前白蛋白(PA)在不同类型肝脏疾病中的含量变化。方法:纳入250例不同类型的肝脏疾病患者,每种50例,包括急性肝炎、慢性肝炎、肝硬化代偿期、肝硬化失代偿期以及原发性肝肿瘤。对照组为健康人群50例。分别测定PA、TBA、TB在上述受试者的血清水平。结果:急性肝炎组、慢性肝炎组、代偿性肝硬化组、失代偿肝硬化组PA值与正常对照比较(P<0.05),均有统计学意义,其中原发性肝肿瘤组数值最低,与正常对照比较(P<0.01)。各组的TBA值与正常对照比较( P<0.05),均有统计学意义。对于TB值仅急性肝炎组与正常对照比较(P<0.01),均有统计学意义,其余各组与正常对照比较没有统计学意义。在急性肝炎组和原发性肝肿瘤组,TB阳性率最高,其余各组均为TBA阳性率最高。结论: TB和TBA对各类肝脏疾病具有一定的诊断价值;PA、TBA、TB的不同测定对肝脏疾病的鉴别诊断有指导作用。  相似文献   

6.
吸毒人群中医病理因素的临床研究   总被引:1,自引:0,他引:1  
目的 研究吸毒人群的中医病理因素特点.方法 对吸毒者和健康者进行对照研究,中医病理因素采用证素辨证方法采集.结果 吸毒组肝证素积分频数最高;与健康组相比,吸毒组的五脏病位证素积分值均差异有统计学意义(P<0.01);吸毒组痰、湿、气滞和阴虚等病性证素积分频数最高;与健康组相比,吸毒组的病性证素积分值均差异有统计学意义(P<0.01).结论 毒品成瘾形成是多脏腑(肝、肾、脾)功能失调的表现,多属虚实夹杂之证.虚证病性证素主要以阴虚为主;实证病性证素主要以痰、湿、气滞为主;病位主要在肝、肾.  相似文献   

7.
目的:分析慢性乙型重型肝炎(以下简称慢重肝)患者外周血各亚群淋巴细胞绝对值的特点.方法:慢重肝患者61例,乙肝引起的肝硬化26例,慢性乙型肝炎21例,健康志愿者10例.采用流式细胞仪检测各自外周血淋巴细胞CD3 、CD4 、CD8 、NK细胞(CD3-/CD16 /CD56 )、NKT细胞(CD3 /CD16 CD56 )等亚群表达百分比,计算各淋巴细胞亚群绝对值,并进行统计学分析.结果:与乙肝引起的肝硬化、慢性乙型肝炎患者以及健康志愿者相比,慢重肝患者CD3 、CD4 及CD8 T淋巴细胞的绝对值均明显降低(P<0.01或P<0.05);与存活者相比,慢重肝死亡患者外周血淋巴细胞、CD3 、CD4 、CD8 、NK细胞、NKT细胞绝对值均有一种降低的趋势但尚未达到统计学意义.结论:慢重肝患者存在一定程度的细胞免疫功能紊乱,可能与其预后存在一定的相关性.  相似文献   

8.
目的:探讨慢性肝炎患者肝纤维化指标与脾静脉超声联合检查对肝纤维化的诊断价值。方法:选择73例慢性肝炎患者进行肝纤维化与脾静脉、脾容积超声联合检查,并与同期住院的30例急性肝炎患者对比,做相关性分析。结果:慢性肝炎各项指标均显著高于对照组(P<0.01),各项指标与肝纤维化呈正相关。结论:肝纤维化与脾静脉超声联合检查对肝纤维化的诊断有较大价值。  相似文献   

9.
目的 分析不同肝病患者的血脂变化规律.方法 检测260例肝病患者与57例健康对照者的TG、TC、HDL-C、LDL-C.结果 健康对照组、急性肝炎组、轻度慢性肝炎组、中度慢性肝炎组、重度慢性肝炎组、肝硬化组、重型肝炎组之间TG、TC、HDL-C、LDL-C差异均有统计学意义(P<0.05);急性肝炎组、轻度慢性肝炎组TG、TC、HDL-C、LDL-C与健康对照组相比差异均无统计学意义(P>0.05);中度慢性肝炎组、重度慢性肝炎组、肝硬化组、重型肝炎组TG、TC、HDL-C、LDL-C与健康对照组相比差异均有统计学意义(P<0.05);中度慢性肝炎组、重度慢性肝炎组、肝硬化组、重型肝炎组之间TG相比差异无统计学意义(P>0.05),但TC、HDL-C、LDL-C相比差异均有统计学意义(P<0.05).结论 中重度慢性肝炎、肝硬化、重型肝炎常合并明显的血脂代谢紊乱,且不同肝病的血脂代谢紊乱程度不一致.  相似文献   

10.
思美泰干预肝内胆汁淤积性病毒性肝炎临床体会   总被引:1,自引:0,他引:1  
辜金莲  丘惠嫦 《河北医学》2007,13(4):406-409
目的:观察思美泰治疗胆汁淤积性病毒性肝炎的疗效.方法:110例肝内胆汁淤积性病毒性肝炎患者随机分为A(治疗组)、B(对照组)两组,分别用思美泰和门冬氨酸钾镁治疗,疗程均为4周.结果: 思美泰对淤胆型肝炎皮肤瘙庠的有效率为86.67%(13/15),与对照组比差异有显著性P<0.05;对慢性肝炎合并肝内胆汁淤积患者皮肤瘙痒、纳差的有效率分别为88.24%(15/17)、82.35%(14/17),与对照组比差异有显著意义P<0.05;思美泰治疗后,淤胆型肝炎和急、慢性肝炎合并肝内胆汁淤积患者血清总胆红素(STB)、血清结合胆红素(SCB)、ALT、AST的降幅明显高于对照组P<0.05;治疗后ALP的下降有显著性意义P<0.05,STB、SCB的复常率显著高于对照组P<0.05;淤胆型肝炎和慢性肝炎合并肝内胆汁淤积患者ALT的复常率较对照组差异有显著意义P<0.05;慢性肝炎合并肝内胆汁淤积患者血清白蛋白在治疗后的增高也有显著性意义P<0.05.结论:思美泰治疗胆汁淤积性病毒性肝炎疗效较好,优于门冬氨酸钾镁,没有明显不良反应.  相似文献   

11.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

12.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

13.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

14.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

15.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

16.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

17.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

18.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

19.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

20.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

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