改性甲基二苯乙炔基硅烷的固化及其复合材料

制备了双（N-间乙炔基苯基邻苯二甲酰亚胺）醚（BE）改性甲基二苯乙炔基硅烷（MDPES）（BE／MDPES）。研究表明，选择BE／MDPES的固化温度时，必须同时考虑网络的形成反应和BE中醚键的断裂反应。当最终固化温度控制在300℃时，mBE／mMDPES=4／5的玻璃纤维复合材料的弯曲强度高达275MPa，235℃时的高温弯曲强度为241MPa，保留率达88．5％，且优异的耐热性能与介电性能保持不变。     

聚苯乙炔基苯基硅氧硼烷树脂及其复合材料的性能

将双(N-间乙炔基苯基邻苯二甲酰亚胺)醚(DAIE)和双酚A型氰酸酯(CE)分别加到聚苯乙炔基苯基硅氧硼烷(PSOB)和三苯乙炔基苯基硅烷（PTPES）混合体系中进行改性,制得两种纤维增强复合材料PSOB-PTPES-DAIE和PSOB-PTPES-CE。研究了固化后树脂的热稳定性能、力学性能、介电性能和耐水性能。结果表明：两种改性树脂高温下均保持了良好的耐热性能,在氮气中质量损失5%时的温度(T5%)最高可达534 °C,800 °C下质量保留率最高可达62.9%。所制备的两种复合材料体系常温下弯曲强度可达250 MPa以上,240 °C下的弯曲强度最高可达202 MPa。饱和吸水率最低可达1.4%,耐水性能优良。不同处理条件下的复合材料介电常数与介电损耗角正切值变化较小,介电性能良好。     

聚甲基二间苯二乙炔基硅烷改性二氧化双环戊二烯环氧树脂及其复合材料的性能

用聚甲基二间苯二乙炔基硅烷树脂(PSA）改性二氧化双环戊二烯（R122环氧树脂）得到R122/PSA树脂体系,并以该树脂为基体制备了玻璃纤维复合材料。通过FTIR、DSC和TGA研究了R122/PSA树脂的固化反应及其耐热性能,同时研究了R122/PSA基复合材料的力学性能、耐热性能、介电性能和耐水性能。结果表明：改性树脂在高温下保持了良好的耐热性能,mPSA/mR122=02的固化物在800 °C下质量保留率比纯R122树脂的提高了30%。所制备的复合材料常温下弯曲强度达到735 MPa,220 °C下的弯曲强度达到4184 MPa,不仅保留了良好的力学性能,而且耐热性能得到了很好的提升,同时其浸泡96 h后的吸水率仅为065%,耐水性能优异。     

顺酐化聚丁二烯改性DAIP树脂的性能

研究了顺酐化聚丁二烯(MPB)对间苯二甲酸二烯丙基酯(DAIP)树脂浇铸体冲击性能、耐热性能、介电性能以及耐盐水性能的影响.结果表明,随着 MPB 含量的增大,DAIP的韧性增大;体系中加入 20%MPB 后,树脂浇铸体的冲击性能达到了 9.2 kJ/m2,比纯 DAIP 的提高了298%;浇铸体的耐盐水性能也大大地提高,在 w=0.10 的 NaCl 溶液中浸泡7 d后,浇铸体的质量变化百分率仅为纯 DAIP 的40%,介电损耗角正切的变化量也仅为纯DAIP的 18.9%;耐热性能和介电性能都略微有下降,但是降低的幅度不大.     

硅炔杂化树脂改性有机硅树脂及其复合材料的性能

用一种硅炔杂化树脂聚（甲基硅烷-二乙炔基苯）（PSP）改性有机硅树脂（HS）,通过FT-IR和TGA研究了树脂体系的固化反应及耐热性,并对制备的复合材料进行力学性能、耐热性能和介电性能研究。结果表明：当HS与PSP的质量比为5∶5时综合性能最优,树脂体系在氮气氛围下质量损失5％时的温度(Td5)为691 °C,1 000 °C时质量保留率为88%;HS-PSP树脂短切玻纤复合材料冲击强度为21 kJ/m2,弯曲强度为65 MPa,200 °C时的弯曲强度高温保留率为78%,介电常数为4.6,介电损耗因数为7.9×10-3,体积电阻为6.7×1013 Ω。改性后的复合材料具有优异的力学、耐热和介电性能。     

TEAS-DAIE树脂基玻璃纤维复合材料性能的研究

四（3乙炔苯胺）基硅烷(TEAS)具有合成简单、溶解性好、固化温度低且固化后耐热性好等优异的性能,但以其作为基体树脂制得的玻璃纤维增强复合材料的力学性能较低。将双（N间乙炔基苯基邻苯二甲酰亚胺）醚(DAIE)与四（3乙炔苯胺）基硅烷(TEAS)以适当的比例混合,制得复合材料基体树脂,即TEASDAIE。用TEASDAIE与玻璃纤维复合制得复合材料,并研究了该复合材料的耐热性、力学性能、介电性能、吸水性、断面形貌等。结果表明：复合材料具有优良的力学性能,其在常温下的弯曲强度为385.7 MPa,2     

含Zr聚乙炔基苯胺树脂的制备

以四氯化锆、苯乙炔和间乙炔基苯胺(APA)为原料,通过先驱体合成法制备新型含锆有机先驱体树脂——含Zr聚乙炔基苯胺树脂(ZAPA)。通过FT-IR表征了其结构,利用DSC及FT-IR研究了其固化反应,通过TG研究了其固化物的耐热性能,采用XRD和EDS研究了其固化物的烧结性能。结果表明：ZAPA树脂可以发生固化交联反应,其固化物相对于APA的固化物具有更好的耐热性能,在N2气氛下,ZAPA树脂固化物失重5%的温度为445 °C,1 000 °C下的质量残余率为43.7%;在空气气氛中,1 000 °C下烧结5 h后,可形成ZrO2晶体。     

改性硅炔树脂及其复合材料的耐热性能

通过格氏试剂反应制得了改性硅炔杂化树脂（GMD）。采用DSC、TGA等分析方法研究了GMD的固化反应及耐热性能。结果表明：GMD固化物在氮气气氛下质量损失5%时的温度(Td5)为631 °C,1 000 °C时的质量残留率为59%。所制备的玻璃纤维增强复合材料在常温下的弯曲强度为320 MPa,在240 °C的弯曲强度保留率高达90%,空气条件下经500 °C处理7 min后,质量保留率仍达到99.7%。该复合材料的玻璃化温度大于400 °C,具有优异的耐热性能、力学性能及介电性能。     

新型自阻燃联苯基二元氰酸酯树脂的合成、表征与性能

首先以4,4-联苯二甲醚(BMBP)和2,6-二甲基苯酚为单体、对甲苯磺酸(PTS)为催化剂,合成了联苯基酚单体(BDBP)。将BDBP进行氰化后,成功制备了一种新型联苯基二元氰酸酯(BDBPCy)。利用红外光谱(FT-IR)和质谱(MS)对酚中间体及氰酸酯单体结构进行了表征。通过差示扫描量热法(DSC)、动态热机械分析(DMA)等测试手段考察了固化后树脂的热性能、力学性能、介电性能、耐湿热性及阻燃性能。结果表明：BDBPCy树脂结构中引入的联苯结构,使得树脂在固化后具有良好的热稳定性及自阻燃性能,800 °C的质量残留率为42%,玻璃化转变温度为258 °C,UL-94垂直燃烧实验测试结果为V-0级别。同时,结构中的大体积联苯基团和邻位甲基基团进一步提高了树脂的介电性能和耐湿热性能。     

室温固化DAIP树脂体系的性能研究

对室温固化ＤＡＩＰ树脂体系的加工性能，树脂浇铸体的力学性能，介电性能，耐热性能以耐水性能进行了研究。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…