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1.
目的:观察纳米银敷料在神经外科褥疮患者中的护理效果。方法将70例褥疮患者随机分为2组:纳米银敷料组和对照组,各35例。纳米银敷料组患者使用纳米银敷料护理褥疮。对照组患者使用普通无菌纱布护理褥疮。观察2组患者2周后创面愈合情况,记录2组患者的住院时间和住院费用。结果纳米银敷料组的创面愈合情况(治愈15例,好转11例,无效9例)优于对照组(治愈8例,好转11例,无效16例)(Z=-2.007, P=0.045),纳米银敷料组的住院时间(47.8±9.7)d短于对照组(54.5±13.3)d(t=3.152,P=0.0026),而住院费用(13658.3±384.8)元则少于对照组(16846.8±428.9)元(t=2.775,P=0.0041)。结论纳米银敷料对褥疮患者有良好的护理效果。  相似文献   

2.
目的分析纳米银医用抗菌敷料在烧伤患者治疗中的应用效果,并对护理干预体会进行总结。方法选取2013年3月至2017年2月60例烧伤患者,随机分组,对照组(n=30)给予常规护理模式,观察组(n=30)在此基础上给予纳米银医用抗菌敷料,并给予对症护理,比较2组患者临床护理效果。结果观察组疼痛评分低于对照组,且发热时间、创面愈合时间均低于对照组(P0.05)。结论烧伤患者应用纳米银医用抗菌敷料期间,护理人员为其做好对症护理干预,对促进患者预后意义重大。  相似文献   

3.
目的:观察纳米银抗菌敷料和凡士林敷料在治疗老年Ⅱ度烧伤中的疗效。方法:治疗组:创面消毒清创后使用纳米银抗菌敷料覆盖,每日换药;对照组:创面消毒清创后使用凡士林敷料覆盖,每日换药;定期检测血常规、细菌培养,观察两组创面愈合情况。结果:治疗组的白细胞和中性粒细胞值在治疗过程中下降的趋势高于对照组,但差异均无统计学意义(P0.05);治疗组和对照组细菌培养检出率分别为15.6%和40.6%;治疗组创面愈合时间明显短于对照组,其差异具有统计学意义(p=0.048)。结论:纳米银抗菌敷料在治疗老年II度烧伤患者中,可以明显降低创面感染风险,缩短愈合时间。  相似文献   

4.
孙权 《当代医学》2014,(35):55-56
目的探讨银离子敷料加清创胶治疗糖尿病足的临床疗效。方法选取邵阳市医学高等专科学校附属医院收治的因感染引起的糖尿病足患者98例,随机分为实验组和对照组,实验组(n=50)给予银离子敷料加清创胶治疗,对照组(n=48)给予常规换药治疗,对比分析2组患者的疗效、创面愈合情况和并发症情况。结果实验组总有效率为98.0%,显著高于对照组的81.3%,2组差异有统计学意义(P〈0.05);实验组创面愈合时间较短,愈合情况显著优于对照组,2组差异有统计学意义(P〈0.05);2组并发症情况差异无统计学意义。结论银离子敷料加清创胶治疗糖尿病足效果显著,能有效提高患者糖尿病足的治疗情况,且无明显并发症,值得临床推广应用。  相似文献   

5.
目的:探讨纳米银敷料联合人表皮生长外溶因子凝胶制剂在深Ⅱ度烧伤创面治疗中的应用效果。方法:选取汕头市第二人民医院收治的74例深Ⅱ度烧伤患者作为研究对象,以随机数表法分为对照组与观察组,每组各37例。全部患者均实施彻底清创,对照组在清创后采用人表皮生长外溶因子凝胶制剂治疗,观察组在对照组基础上加用纳米银敷料治疗,比较两组患者治疗效果。结果:相较于对照组,观察组治疗后视觉模拟评分法(VAS)评分与创面细菌阳性率更低,差异有统计学意义(P<0.05);观察组治疗1周与2周后的创面溶痂率更高,差异有统计学意义(t=11.501、10.102,P<0.05);观察组完全溶痂时间与创面愈合时间更短,差异有统计学意义(t=7.481、5.990,P<0.05);观察组治疗2周后的降钙素原(PCT)与高敏C反应蛋白(hs-CRP)均低于对照组,差异有统计学意义(t=6.259、12.689,P<0.05)。结论:纳米银敷料联合人表皮生长外溶因子凝胶制剂在深Ⅱ度烧伤创面治疗中的应用效果确切,可缩短创面愈合时间。  相似文献   

6.
彭杨  秦花  覃岭 《西部医学》2020,32(3):430-433
【摘要】 目的 观察纳米银敷料联合中药补阳还五汤对糖尿病足溃疡的临床疗效。 方法 选取我院2016年3月~2018年3月收治的128例糖尿病足溃疡患者,将其随机分为对照组、治疗组1、治疗组2和联合治疗组,每组32例。对照组给予常规外科换药处理及糖尿病足内科治疗,治疗组1采用隔日更换1次纳米银敷料覆盖,治疗组2给予口服中药补阳还五汤,联合治疗组采用隔日更换1次纳米银敷料覆盖和口服中药补阳还五汤治疗。治疗前及治疗后第12、24、48 d取伤口分泌物行细菌培养,每次更换敷料时测量伤口面积,检测红细胞沉降率、CRP、胱抑素C。 结果 联合治疗组12、24、48 d糖尿病足溃疡病原菌阳性率低于同期对照组 (P<0.05),联合治疗组12、24、48 d后伤口面积明显小于同期对照组(P<0.05),伤口愈合率高于对照组(P<0.05),红细胞沉降率、CRP和胱抑素C低于同期对照组(P<0.05)。治疗组1和治疗组2疗效与同期对照组比较差异无统计学意义(P>0.05)。 结论 纳米银敷料联合中药补阳还五汤治疗糖尿病足溃疡能有效抑制溃疡局部细菌生长,促进伤口愈合,提高糖尿病足溃疡愈合的临床疗效。  相似文献   

7.
目的:观察皮肤创面无机诱导活性敷料联合高压氧治疗糖尿病足慢性溃疡的临床疗效。方法选择糖尿病足慢性溃疡患者100例,随机分为实验组和对照组(n=50)。在常规治疗的基础上,实验组采用皮肤创面无机诱导活性敷料联合高压氧治疗,对照组采用皮肤创面无机诱导活性敷料治疗,比较2组的临床疗效及治疗前后患者皮肤感觉、溃疡面积、血糖血脂方面的变化。结果实验组在治疗疗效方面、改善血糖、降低血脂等方面都显著优于对照组,差异有统计学意义(P<0.05)。结论皮肤创面无机诱导活性敷料联合高压氧治疗糖尿病足慢性溃疡有明显疗效。  相似文献   

8.
目的比较纳米银敷料与磺胺嘧啶银霜两种方法治疗烧伤创面的临床效果。方法将124例烧伤患者随机均分为纳米银敷料组和磺胺嘧啶银霜组,通过两组患者的细菌感染率、创面愈合时间、手术植皮率、瘢痕发生率和毒副反应发生率比较两组临床疗效差异。结果两组患者细菌感染率和毒副反应发生率比较无显著差异;纳米银敷料组患者创面愈合时间为(89±1.5)d,明显短于磺胺嘧啶银霜组的(13.2±1.2)d(P〈0.05);纳米银敷料组患者手术植皮率和瘢痕发生率分别为6.5%和24.2%,均显著少于磺胺嘧啶银霜组的41.9%和54.8%(P〈0.05)。结论纳米银敷料治疗烧伤创面效果明显优于磺胺嘧啶银霜,能缩短创面愈合时间,提高创面愈合率,值得临床广泛推广使用。  相似文献   

9.
目的:观察金因肽联合纳米银医用敷料在治疗Ⅱ度烧伤创面的疗效。方法:Ⅱ度烧伤创面患者78例,随机分为治疗组40例,应用金因肽联合纳米银医用敷料换药;对照组38例,应用0.5%碘伏纱布,观察两组创面愈合情况和抑(杀)菌效果。结果:与对照组比较,治疗组创面愈合时间明显缩短,差异有统计学意义(P〈0.05),抑(杀)菌效果显著。结论:金因肽联合纳米银医用敷料能有效抑制或杀灭烧伤创面病原菌,明显缩短烧伤创面愈合时间。  相似文献   

10.
目的:观察银离子敷料联合高压氧治疗在糖尿病足溃疡创面护理中的效果。方法:68例糖尿病足患者随机分成对照组34例和试验组34例,对照组采用银离子敷料置于溃疡,试验组采用银离子敷料联合高压氧治疗,比较两组患者之间的视觉疼痛评分(VAS)、创口创面评分(WBS)、换药次数和满意率。结果:对照组VAS评分为(3.4±0.4),试验组VAS评分为(2.1±0.3),两组相比较差异有统计学意义(P<0.05);对照组WBS评分为(11.4±1.5),明显低于试验组的(16.6±2.8),差异有统计学意义(P<0.05);对照组和试验组换药次数分别为(26.4±4.1)次和(15.4±2.7)次,两组比较有统计学差异(P<0.05);对照组患者满意率为61.8%,明显低于试验组的(94.1%),两组相比较差异有统计学意义(P<0.05)。结论:银离子敷料联合高压氧治疗糖尿病足溃疡可显著加速创面愈合,减少换药次数、缓解患者疼痛并减轻护理工作量。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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