75岁以上老年腔隙性脑梗死临床特征117例分析

目的 探讨老年腔隙性脑梗死的类型与临床特征.方法 对以腔隙性脑梗死就诊的老年患者117例回顾分析.结果 经做头部CT或核磁共振成像、脑血管多普勒超声并结合临床资料诊断:纯运动性轻偏瘫71例,纯感觉性卒中29例,共济失调性轻瘫7例,构音障碍-手笨拙综合征6例,感觉运动性卒中4例.全部做低密度脂蛋白胆固醇、超敏C-反应蛋白、幽门螺旋杆菌、同型半胱氨酸,其阳性率依次为83.0%、96.6%、68.4%、75.2%.结论 老年腔隙性脑梗死病因复杂,临床类型多样,应详细询问病史及查体,系统性做相关辅助检查,综合分析后确定诊断.     

75岁以上老年腔隙性脑梗死临床特征117例分析

目的 探讨老年腔隙性脑梗死的类型与临床特征.方法 对以腔隙性脑梗死就诊的老年患者117例回顾分析.结果 经做头部CT或核磁共振成像、脑血管多普勒超声并结合临床资料诊断:纯运动性轻偏瘫71例,纯感觉性卒中29例,共济失调性轻瘫7例,构音障碍-手笨拙综合征6例,感觉运动性卒中4例.全部做低密度脂蛋白胆固醇、超敏C-反应蛋白、幽门螺旋杆菌、同型半胱氨酸,其阳性率依次为83.0%、96.6%、68.4%、75.2%.结论 老年腔隙性脑梗死病因复杂,临床类型多样,应详细询问病史及查体,系统性做相关辅助检查,综合分析后确定诊断.     

腔隙性脑梗死156例临床分析

目的 研究腔隙性脑梗死的危险因素、 临床特点及其在诊断和治疗中的价值.方法 对156例腔隙性脑梗死患者的危险因素、首发症状、影像学检查以及治疗转归进行综合分析.结果 腔隙性脑梗死危险因素众多,占比最高的危险因素由高到低排列:高血压、吸烟、颈动脉狭窄超过50%及糖尿病,其他因素占比不足20%;患者症状多以肢体无力、语言不清及肢体麻木、 头晕为主,临床分型分为纯运动性轻偏瘫(PMH)、纯感觉性卒中(PSS)、共济失调性轻偏瘫(AH)、构音障碍-手笨拙综合征(DCHS)、感觉运动性卒中(SMS)等.多发生于基底节区、脑叶及脑干,小脑少见.经治疗,68例痊愈,72例好转,16例病情恶化.结论 正确认识腔隙性脑梗死,对于其治疗及预防复发有重要意义.     

老年人腔隙性脑梗死72例临床分析

通过回顾性分析72例老年人腔隙性脑梗死(LI)的临床资料,以探讨老年人LI的临床特点及防治。结果显示72例老年人中纯运动性轻偏瘫及其变异型32例,纯感觉型2例,感觉运动型卒中7例,构音不全手笨拙综合征7例,腔隙状态6例,无症状LI 13例。提示本病预后良好,MRI对LI的诊断优于CT。因此,积极防治高血压病、冠心病、糖尿病、高脂血症及戒烟、适量饮酒是防治老年人LI的关键。     

腔隙性脑梗塞100例临床分析

本组报道经磁共振成像(MRI)证实的腔隙性脑梗塞100例中有纯运动性偏瘫、纯感觉性卒中、感觉运动性卒中、呐吃-手笨综合征、共济失调性轻偏瘫等临床较常见的类型。此病大都起病缓慢,症状较轻,预后良好。一过性脑缺血发作可以是腔隙性脑梗塞的症状之一,也可能是发病前期的临床表现。高血压常是发生本病的直接原因。因此早期防治高血压病,是防止本病发生的关键。抗凝疗法对本病不宜使用。     

腔隙性脑梗死的病因探讨及防治(附197例临床分析)

目的 探讨腔隙性脑梗死的病因、临床CT、MRI特点及防治中应注意的问题.方法 对197例腔隙性脑梗死作回顾性分析.结果 197例患者有高血压史155例(78.7%),糖尿病124例(62.9%),冠心病102例(51.8%),高脂血症110例(55.8%),短暂性脑缺血发作35例(17.8%),烟酒嗜好89例(45.2%).按Fisher分型标准进行分型:单纯运动性轻偏瘫(PMH)98例,PMH变异型12例,感觉运动性卒中(SMS)9例,单纯感觉性卒中 (PSS)6例,构音-手笨拙综合征(DHS)3例,腔隙状态(LS)23例,无症状腔隙性梗塞(ALI)35例,丘脑内囊综合征(TICS)11例.病灶于基底节区最多见,(121例,61.4%),其次为内囊、侧脑室、侧脑室旁及放射冠,少见部分有丘脑、额叶、顶叶及脑干.结论 治疗高血压、糖尿病、高脂血症等合并症乃是防治本病的     

腔隙性脑梗死50例临床分析

目的探讨腔隙性脑梗死(LCL)的临床特点。方法回顾性分析50例LCL患者的临床资料。结果本组50例患者中高血压病41例(82%),高脂血症17例(34%),高粘血症20例(40%),糖尿病12例(24%)。常见临床类型为单纯运动性偏瘫22例,单纯感觉性卒中10例,无症状腔隙性梗塞6例,共济失调性卒中5例,腔隙状态5例,CT漏诊2例,后经MRI检查确诊。病灶部位主要在基底节区22例,内囊6例,丘脑区4例。结论高血压是LCI的直接原因,腔隙病灶主要位于基底节;腔隙状态的预后差,MRI对脑干、小脑及Φ<5mm或发病24h内的病灶优于CT。     

脑腔隙综合征154例临床分析

本文对154例脑腔隙综合征结合临床及CT所见进行了分析。年龄在50岁以上者占91.6%,有高血压者占72.7‰。临床表现以纯运动性偏瘫最多见(48.7%),其次为感觉运动性卒中(20.8%),纯感觉性卒中约占4.7%。本组149例均经CT检查,发现有腔隙灶占97%。共检出腔隙灶258个,基底节区最多,其它依次为放射冠、内囊、额叶、丘脑、脑干及其它部位白质。本文还对临床表现典型而CT检查阴性的5例进行了讨论,提出了提高CT扫描阳性率的几种方法。观察了本组的治疗过程,认为本病预后良好。     

内囊腔隙梗塞45例分析

本文４５例内囊腔隙梗塞中，有明确诱因者１７例，表现为纯云霞生偏瘫者６例，纯感觉性卒中３例，构音障碍－手笨拙综合征６例，感觉运动性卒中２例，轻偏瘫－痴呆７例，纯精神障碍１６例，其他５例，ＣＴ检查发现腔隙灶共１１８个，双内囊前肢１６例，左内囊前肢２１例，右内囊前肢１例，其他５例。     

39例不典型腔隙综合征患者的临床研究

本研究旨在描述不典型腔隙综合征（ALS）患者的临床特征，资料来源于前瞻性急性卒中登记处。12年内根据前瞻性卒中登记处提供的资料共有2500例急性卒中患者住院治疗，其中39例患者被确诊为ALS并经影像学（CT或MRI）证实有腔隙灶。所有急性卒中患者的1．8％、急性缺血性卒中患者的2．1％以及腔隙综合征患者的0．8％出现ALS。ALS包括构音障碍轻面瘫（n=12）或孤立性构音障碍（n=9）、孤立性偏侧共济失调（n=4）、伴有短暂性核间性眼肌麻痹的纯运动性轻偏瘫（n=4）、伴有短暂性皮质下失语的纯运动性轻偏瘫（n=3）、单侧（n=2）或双侧（n=3）丘脑旁正中梗死综合征以及偏侧舞蹈症-偏侧投掷症（n=2）。96％的ALs患者源于小血管病变，动脉粥样硬化性血栓性脑梗死及心源性梗死各有1例患者，二者均表现为纯构音障碍，患者的预后良好（院内死亡率为0％，出院时无症状率为28．2％）。经多变量分析，发现语言障碍、恶心（呕吐）、缺血性心脏病和感觉症状与ALS密切相关。总之。ALS是一种罕见的卒中亚型（1／14腔隙性卒中），占腔隙性卒中的6．8％，孤立性构音障碍或构音障碍轻面瘫是最常见的表现形式。该罕见ALS的预后良好。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.