妊娠并发高脂血症性胰腺炎临床分析

目的探讨妊娠并发高脂血症性胰腺炎的临床特征、诊断及处理。方法回顾性分析自1995年至2005年间收治的11例妊娠合并急性胰腺炎（acute pancreatitis，AP）病例，其中妊娠合并急性胆石性胰腺炎（acute gallstone pancreatitis，AGP）8例，妊娠并发高脂血症性胰腺炎（hyperlipidemic pancreatitis，HLP）3例，以同期住院终止妊娠者作为对照，分析妊娠并发高脂血症性胰腺炎的实验室检查结果及治疗措施。结果高脂血症性胰腺炎血、尿淀粉酶升高程度较胆石性胰腺炎轻，血脂升高程度及发生多器官衰竭者的比例明显高于胆石性胰腺炎者。结论妊娠并发HLP对孕妇及胎儿危害大，早期诊断与手术治疗是阻止妊娠并发HLP出现器官功能障碍的最有效手段。     

不同临床结局重症急性胰腺炎患者临床特点的对比研究

目的探究不同临床结局的重症急性胰腺炎的临床特点。方法对我院收治的63例重症急性胰腺炎患者的临床资料进行回顾性分析,根据临床结局,分为存活组与死亡组,对比两组患者的临床特点。结果存活组与死亡组患者的例数分别为53例(84.13%)与10例(15.87%),特发性重症急性胰腺炎患者的清创手术率与病死率均显著高于高脂血症患者与胆源性患者,差异具有统计学意义(均P<0.05);死亡组急性生理与慢性健康(APACHE)Ⅱ评分、CT严重指数(CTSI)、年龄、多脏器功能障碍/衰竭发生率以及局部并发症发生率均显著高于存活组,差异具有统计学意义(均P<0.05)。结论重症急性胰腺炎患者的死亡与病因、年龄、多脏器功能障碍/衰竭、局部并发症等因素有关,值得进一步推广研究。     

氧代谢监测在重症急性胰腺炎病程发展过程中的应用价值

目的探讨在急性胰腺炎并发多器官功能障碍综合征（MODS）发生发展中氧代谢监测的价值。方法选择121例各类急性胰腺炎患者,采集相关氧代谢检测数据和参数,比较水肿组和重症组,MODS和NMODS组,存活组与死亡组各指标间的变化,以水肿组相应指标测定结果作为对照,依据病性严重程度及并发MODS情况对病情或预后进行量化评价。结果氧代谢水平在重症胰腺炎发病后即发生异常,与严重程度、低血容量性休克、全身炎症反应综合征（SIRS）以及是否并发呼吸系统合并症等有关;并发MODS患者氧代谢水平变化更为明显,与水肿组对照组和NMODS组比较相关氧代谢比值改变均有显著性差异。结论氧代谢水平变化与重症急性胰腺炎并发MODS的发生发展密切相关,动态监测组织细胞氧代谢状况对MODS具有一定的意义。     

重度子痫前期并发多器官功能障碍的诊治及预后

目的:探讨重度子痫前期并发多器官功能障碍(MODS)的临床特点、诊治和预后。方法:对34例重度子痫前期并发MODS的患者的临床资料进行回顾性分析。结果:34例患者中,孕28~32周的有6例,孕32~34周的20例,孕34~40周的8例;34例患者均于早期诊断后行剖宫产术终止妊娠,产妇结局良好,其中有2例胎儿胎死宫内,3例新生儿死亡,均为早产儿。结论:对于重度子痫前期并发多器官功能障碍综合征处理的关键是积极地预防和治疗重度子痫前期,适时地选择合适的方式终止妊娠,加强监护,保护相关脏器的功能和全身支持疗法可改善母婴结局。     

妊娠合并胰腺炎11例临床治疗分析

目的探讨妊娠合并急性胰腺炎的临床特点及治疗原则。方法回顾性分析我院11例妊娠合并急性胰腺炎的发病特点、辅助检查、治疗方法及结局。结果11例孕妇无1例死亡。5例轻型患者行保守治疗痊愈,母婴健康;6例重型患者中2例胎儿死亡,3例保守治疗后病情加重,行剖腹产终止妊娠后胎儿存活。结论妊娠合并急性胰腺炎的发生与胆结石和高脂血症有关,在临床上有其特殊性,及时诊断和"个体化"综合治疗是关键。     

脐带绕颈胎儿脐动脉血气变化的研究

为了了解脐带绕颈胎儿脐动脉血气变化,选取228例孕37～42周孕妇,脐带绕颈组167例(按绕颈松紧程度分组),对照组61例,产后均行脐动脉血气分析.结果发现脐带绕颈较紧组有25例发生酸中毒,与对照组有显著性差异(P＜0.05);其中混合性酸中毒占66%,代谢性酸中毒占8%.提示脐带绕颈较紧胎儿酸中毒的发生率较高,以混合性酸中毒和代谢性酸中毒多见.     

妊娠期糖尿病患者妊娠结局62例临床分析

目的 探讨妊娠期糖尿病(GDM)对孕妇妊娠结局及胎儿的影响.方法 将62例妊娠期糖尿病的患者与同期60例健康孕妇进行比较,分析两组患者妊娠结局资料.结果 妊娠期糖尿病患者出现妊娠高血压综合征、羊水过多、巨大儿、胎儿宫内窘迫、胎膜早破、高脂血症、早产、剖宫产等发生率和高胆红素血症发生率明显多于对照组(P＜0.05).结论...     

感染性休克并发多器官功能障碍综合征患者的急救和护理分析

目的：探讨感染性休克并发多器官功能障碍综合征患者的临床急救与护理方法。方法选取我院收治的感染性休克并发多器官功能障碍综合征患者84例随机分为护理组与对照组,每组42例。对照组患者给予对症护理,护理组患者给予系统护理,记录2组患者的病死率。结果经积极救治后,护理组患者死亡11例（26.19%）,对照组患者死亡14例（33.33%）,2组比较差异具有统计学意义（P〈0.05）。结论系统护理可以改善感染性休克并发多器官功能障碍综合征患者的存活率,但其预后主要与发生功能障碍的脏器数量相关。     

脐带绕颈胎儿脐动脉血气变化的研究

为了了解脐带绕颈胎儿脐动脉血气变化，选取228例孕37－42周孕妇，脐带绕颈组167例（按绕颈松紧程度分组），对照组61例，产后均行脐动脉血气分析。结果发现：脐带绕颈较紧组有25例发生酸中毒，与对照组有显著性差异（P＜0．05）；其中混合性酸中毒占66％，代谢性酸中毒占8％。提示：脐带绕颈较紧胎儿酸中毒的发生率较高，以混合性酸中毒和代谢性酸中毒多见。     

低钙血症对全身炎症反应综合征患者预后的影响

目的　探讨低钙血症对全身炎症反应综合征(SIRS)患者预后的影响。方法　对收治的118例SIRS患者,在入ICU第2天测定血钙值并进行病理生理学及慢性健康状况评分(APACHEII) ,分为:①正常血钙组及低钙血症组:统计APACHEII评分值、多器官功能障碍综合征(MODS)发生率及病死率;②存活组及死亡组:统计两组血钙水平变化。结果　①正常血钙组与低钙血症组APACHEII评分比较差异有高度显著性(P <0 .0 1) ;②存活组血钙异常率低于死亡组,血钙水平明显升高(P均<0 .0 1)。结论　血钙水平反映SIRS患者的病情和预后,可作为判断SIRS预后简易可靠的指标之一。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.