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1.
对20~86岁正常中老年520例的部分呼气流量-容积(PEFV)曲线及有关肺功能指标作了测定,并用多元逐步回归分析法建立了功能残气位呼气流量(VFRC)、用容积校正的VFRC/FVC、各肺容积流量V75、V50、V25以及比时间常数Sτ75、Sτ50、Sτ25的回归方程。VFRC随年龄增长而下降;经容积校正后的VFRC/FVC与年龄的相关性下降。将回归方程用正常人参数作回代检查证明其正确性。结果提示PEFV曲线方法简便,具有理论研究和临床应用意义。  相似文献   

2.
对用力呼吸、肺容积及上气道顺应性对气道阻力(Raw)的影响进行探索后,用阻断法对327例正常老中青年人作了Raw的测定。并测定了FVC、V75、V50、V25。以年龄、身高、FVC为自变量建立了呼气阻力(RE)和吸气阻力(RI)的回归方程。结果表明:RE和RI均有随年龄增长而上升的倾向,FVC、V75、V50、V25则随年龄增长而下降。反映随着年龄增长,肺和中央气道的弹性回缩压均下降,可导致Raw呈不同程度的增加或不变。所测数据和回归方程可供参考应用。  相似文献   

3.
将正常老、中、青少年(6~79岁)1270例流量-容积曲线(F-V曲线)的数据用IBM-PC/XT电算机计算高中低肺容积处的切线时间常数τ_(t75)、τ_(t50)、τ_(t25)。在青少年组:|τ_(t75)|>1s,τ_(t75)>τ_(t50)>τ_(t25),反映曲线的顶部呈圆凸形,曲线凹向容积轴。在老年组:|τ_(t75)|<1s,τ_(t75)>τ_(t50)<τ_(t25),显示曲线的顶部呈峰形,尾端凸向容积轴。中年组居于二者之间。由τ_t反映F-V曲线的形状与Mead用斜率比(SR)所反映者一致。作者并对老人F-V曲线顶部出现峰形和尾端凸向容积轴的原因进行了讨论。  相似文献   

4.
对75例慢性肺心病患者和31例健康成年人测定了各项肺容积和最大用力呼气流量-容积曲线(MEFV)及最大用力吸气流量-容积曲线(MIFV)。结果显示:慢性肺心病患者组肺活量(VC)、补呼气容积(ERV)、一秒率(FEV1.0%)和最大呼气中段流量(MMEF)非常显著降低(P<0.01),功能残气量(FRC)、残气容积(RV)、RV/TLC%均非常显著增高(P<0.001);而最大用力吸气流量-容积曲线(MIFV)15%、25%、50%、75%、85%和MMIF各段平均流量亦有非常显著降低(P<0.001)和用力吸气时间(FIt)明显延长(P<0.001)。表明慢性肺心病患者不仅在最大用力呼时大小气道有严重的通气功能障碍,在最大用力吸气时各段吸气流量亦均有显著降低和吸气时间延长  相似文献   

5.
对用力呼吸、肺容积及上气道顺应性对气道阻力(Raw)的影响进行探索后,且阻断法对327例正常老中青年人作了Raw的测定,并测定了FVC、V75、V50、V25,以年龄、身高、FVC为自变量建立了呼气阻力(RE)和吸气阻力(RI)的回归方程。  相似文献   

6.
阻断法测定300例正常青少年气道阻力   总被引:1,自引:0,他引:1  
对300名12-19岁的青少年用阻断法在RM-6000型四道林理仪上作了气道阻力的测定。同时测定了FVC、V75和V50和V25。以年龄,身高、FVC为自变量,在IBM-PC/XT计算机上用多元逐步回归法建立呼气和吸气阻力的回归方程。  相似文献   

7.
对300名12~19岁的青少年用阻断法在RM-6000型四道生理仪上作了气道阻力(Raw)的测定。同时测定了FVC、·V75和·V50和·V25。以年龄、身高、FVC为自变量,在IBM-PC/XT计算机上用多元逐步回归法建立呼气和吸气阻力的回归方程。结果表明,呼气和吸气阻力都随年龄的增长而下降,FVC、·V75、·V50、·V25则随年龄的增长而上升。反映青少年的气道阻力随肺和气道的生长发育呈比例下,与国外的研究一致。本研究首次为我国青少年提供了生长过程中气道阻力变动的规律和回归方程,宜于卫生和临床工作者的参考应用。  相似文献   

8.
对75例慢性肺心病患者和31例健康成年人测定了各项肺容积和最大用力呼气流量-容积曲线(MEFV)及最大用力吸气流量-容积曲线(MIFV)结果显示,慢性肺心病者组肺活量(VC),补呼气容积(ERV)一秒率(FEV1.0%)和最大呼气中段流量(MMEF)非常显著降低(P〈0.01),功能残气量(FRC),残气容积(RV),RV/TLC%均非常显著增高(P〈0.001),而最大用力吸气流量-容积曲线(M  相似文献   

9.
为评价比时间常数(Sτ)和F-V曲线形状在检查吸烟者小气道功能中的意义,对116例被动和轻、重度主动吸烟者进行了常规肺通气功能、Sτ和F-V曲线形状的研究。常规肺通气功能和F-V曲线形状用常规法测定。Sτ用公式Sτ=1/·V计算。结果表明:凸型F-V曲线分布随吸烟程度加重而上升,·V50、·V25则下降及Sτ50、Sτ25延长在凸型与重度吸烟组一致。Sτ50、Sτ25延长的范围在凸型与重度吸烟组都是预计值的120%~130%,表明小气道功能有轻度障碍。与以前所测COPD患者比较,其Sτ75、Sτ50、Sτ25延长均加剧,表明大小气道都遭累及。故凸型、Sτ50和Sτ25延长、·V50和·V25下降都是检查小气道功能的敏感指标。可推荐临床应用参考。  相似文献   

10.
目的:比较临床常用的六项小气道功能测定方法对小气道功能异常的发现率。方法:健康体检者515例,用自动肺功能测定最大用力呼吸气中段流速(MMEF),最大用力呼气中段流量时间(FET25%~75%),50%及25%肺活量时最大用力呼气流速(V50,V25),三相斜率(△N/L),闭合气量(CV/VC%)等指标。结果:小气道功能异常的发现率最高的是△N/L(84.8%),FET25%~75%(83.4%  相似文献   

11.
Using Knudson's method, the chord time constant, tau ch, tau ch75, tau ch50, tau ch25, and specific time constant, S tau, 1/V75, 1/V50, 1/V25, at high, middle and low lung volumes were calculated from V75, V50 and V25 of the MEFV curves measured previously from 342 healthy children of 3-6 years of age in a nursery. The multiple stepwise regression equation were built with age, height and FVC as independent variables by the IBM-XT/PC computer. The result showed that the S tau corrected by volume from tau ch could reflect the time required for change of unit lung volume more precisely than tau ch owing to the elimination of the influence of lung volume. The S tau was shortened with the increase of age, and was negatively correlate with age and FVC. These facts reflected the growth of lung elastic pressure (PLel) and airway conductance (Gaw) with the increase of age. The prolongation of S tau with the decay of lung volume just reflected the decrease of PLel and Gaw with the decay of lung volume. No regular changes of tau h were observed with age and lung volume. Probably, it was concerned with the complexity of factors affecting the tau ch.  相似文献   

12.
成都地区正常老中青年呼气峰流量探讨   总被引:2,自引:1,他引:1  
OBJECTIVE: To build the normal ranges and regression equations of peak expiratory flow (PEF) in normal young, middle-aged and old persons. METHODS: PEF, FVC, V75, V50, V25 were measured in 393 normal young, middle-aged and old persons with the youngest aged 20 years and the eldest 84 years. Regression equations of PEF were built for younger group (20 yr-49 yr) and elder group (50 yr-84 yr) respectively. RESULTS: PEF, FVC, V75, V50, V25 were decreased with increase of age. The regression equations showed that both in younger and elder groups, PEF was negatively correlated with age in male (P < 0.0001-0.002, r = 0.32-0.39) and positively correlated with FVC in female (P < 0.0001-0.0005, r = 0.32-0.59). PEF was highly correlated to V75 with r = 0.87-0.94 in male and r = 0.93-0.96 in female. The coefficient of variation (CV) of PEF was in normal range (16%-24%) for all age groups except male and female above 70 years old with CV of 30% and 27% respectively. This confirmed the data was reliable. CONCLUSION: The normal ranges and regression equations of PEF constructed as a result of this study for normal humans of 20-84 years old can be put to use in clinical work and public health.  相似文献   

13.
成都地区728例正常青少年呼气峰流量探讨   总被引:1,自引:0,他引:1  
目的 建立正常青少年呼气峰流量(PEF,又称峰流量或最大呼气流量)的正常值及回归方程。方法 对728例8-19岁的正常青少年的PEF以及且力肺活性(FVC)、V75、V50、V25等常规肺通气功能进行了测定。结果 PEF以及FVC、V75、V50、V25均随年龄增长而上升。回归方程中男女青少年的PEF与年龄及FVC呈高度正相关,男性PEF还与体重呈正相关;复相关系数在男、女青少年分别为0.85及0.78。PEF与V75、V50、V25的相关性在男女青少年均高,特别是V75,其相关系数在男、女青少年均达0.98。PEF的变异系数在男女青少年均为15%-20%,处于正常范围。结论 本研究为正常青少年PEF提供的正常值范围和回归方程,可供评价同龄支气管哮喘及其他呼吸道疾病患者肺功能参考。  相似文献   

14.
为探讨吸烟者流量-容积曲线形状形成的切线时间常数,波速机理及其临床意义,测定了22例被动吸烟者和94例主动吸烟者的F-V曲线,由此获取FVC,V75,V50,V25等数据,并计算出高,中,低肺容积的切线时间常数τ175,τ150,τ125,用波速学说进行分析。  相似文献   

15.
Pectusexcavatumisthemostfrequentanteriorchestwalldeformityandisproducedbyposteriordepressionofthesternumandlowercostalcartilage Itoccursmorecommonlyinboysbyalmosta 4∶ 1ratio Thesternumandcostalcartilagethatareangledposteriorlymaydecreasethechestvolume,r…  相似文献   

16.
用切线时间常数分析正常成人F—V曲线形状形成的机理   总被引:7,自引:5,他引:2  
在258例年龄为20-49岁正常成人的F-V曲线上计算高中低肺容积处的切线时间常数τt75,τt50,τt25,将F-V曲线的形状分为平台型,直线型,凸型和凹型和4大类,凸型分布随年龄增长而上升,凹型则反之。F-V曲线顶部形状主要取决于│τt75│的长短。凹型│τt75│最称,顶部缓慢玫落形成较钝的圆形;  相似文献   

17.
To evaluate the clinical significance of the specific time constant (S tau) and F-V curve configuration in testing small airway functions for smokers, routine ventilatory functions, S tau and F-V curve configuration were studied in 116 passive and light, heavy active smokers. Routine ventilatory functions and F-V curve configuration were determined with routine method. S tau were calculated from S tau = 1/V. The results showed that the distribution of convex type rose with the degree of smoking, and the decrease of V50, V25 and elongation of S tau 50, S tau 25 in convex type were just consistent with heavy smokers. The range of elongation of S tau 50 and S tau 25 was 120%-130% of predicted value in both heavy smokers and convex type. These showed there were slight disturbances in functions of small airways. Compared with COPD patients previously measured, their S tau 75, S tau 50, S tau 25 all prolongated to higher degree and meant both large and small airways were affected. Therefore, the convex type, elongation of S tau 50 and S tau 25, and decrease of V50 and V25 were sensitive indices for detecting small airway functions. They can be recommended for clinical application.  相似文献   

18.
According to the principle of linear character of each 10% FVC segment on the FVC-t curve proposed by Jordanoglou, the slope of each segment is nearly equal to 0.1 FVC/2 MMTp. Then MTTp approximately 0.1 FVC/2Vp. The calculations of MTTp at high, middle and low lung volumes are MTT20-30% = 0.1 FVC/2V75, MTT45-55% = 0.1 FVC/2V50, and MTT70-80% = 0.1 FVC/2 V25. The MTTp of 628 cases of normal children and adolescents aged 6-19 yr. was measured by this method. In comparison with the direct method, the results showed that there was no significant difference between the 2 methods. The regression equations built with age as an independent variable showed a good correlation. Obviously, this method is easily performed, and is suitable for the wide use of MTTp.  相似文献   

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