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1.
我们于1987年3~4月份对郑州四中随机抽取的145名男生进行了一次性发育调查,内容包括生殖器与阴毛的测定、手腕部X光摄片及身高、体重测量。结果表明,睾丸纵横径均随年龄增长而增加,睾丸纵径与时间年龄和骨龄间均有相关关系存在,且睾丸纵径随骨龄增加的增长比随时间年龄增加的增长更明显。随着睾丸纵、横径的增长,阴茎亦逐渐发育增大。阴毛在12岁时已开始发育。  相似文献   

2.
目的:探讨男性青少年体格发育水平与性器官发育关系。方法:收集4854例5—14岁男性青少年的身高、体重并计算出体质指数,测量阴茎的长度、周长和睾丸的纵径、横径,观察二者之间的关系。结果与结论:身高与阴茎的长度、周长和睾丸的纵径均呈二次方程曲线关联,而与睾丸横径无明显关联。体重和体质指数与阴茎有长度、周长和睾丸的纵径、横径无明显关联。  相似文献   

3.
正常青少年青春期性征发育调查   总被引:2,自引:0,他引:2  
目的:了解正常青少年青春期性征发育的状况与规律。方法:男性测量睾丸容积,阴茎长度和直径并分期,观察阴毛、腋毛、胡须并分期。观察有无喉结,询问首次遗精时间。女性检查乳房、阴毛、腋毛、大阴唇并分期,询问月经初潮时间,根据性征分期计算性发育指数并评定总性发育程度。结果:制定了睾丸容积、阴茎长度和直径的正常范围,女性乳房、阴毛Tanner分期的年龄分布状况,男、女总性发育程度随年龄增长而增加的趋势。月经初  相似文献   

4.
目的:了解维吾尔族女性青少年身高、体重与性征发育的关系,为制定青春期保健、性征发育教育计划及临床诊断和预防性征发育异常提供理论依据。方法:随机选取573名乌鲁木齐地区维吾尔族8~15岁女性青少年,对其身高、体重、体重指数(BMI)、乳房发育程度、月经初潮、阴毛和腋毛发育进行测量和观察。结果:维吾尔族女性身高速度高峰(PHV)出现在10岁组,快速生长期年龄为10~13岁,体重速度高峰(PWV)和BMI高峰均出现在13岁组。乳房开始发育的高峰出现在ll岁组,阴毛和腋毛开始生长的年龄平均为13岁,月经初潮年龄平均为13.46岁。对乳房、阴腋毛生长发育的影响大小依次为体重、身高、BMI,对月经初潮的影响大小依次为体重、BMI、身高。结论:通过干扰体重可预防女性性征异常发育,乳房开始发育时保持稳定的BMI能使月经正常初潮。  相似文献   

5.
对于性发育延迟这一概念,通常认为:性成熟外表性征较大多数青少年群体性成熟平均年龄落后2年,就看作是性发育延迟。根据临床表现分为以下几种类型,其中有体质因素,也存在其他发病机制.需要区别治疗。!型:体质一躯体型,该型常诊断于12岁以上的男孩,其特征为:①生长延迟,一般落后两个标准差,体态正常呈男性,阴茎、睾丸小,无第二性征。②骨龄延迟2~3年。③一般有近亲及性发育延迟史。④通常这些病孩事先患有没确诊的慢性疾病,如先天性心脏病,亚临床肾病,遗传性脂代谢障碍。部分病史中有反复呼吸道感染及不良的精神社会条件…  相似文献   

6.
目的 研究体重在女性儿童青少年青春发育过程中的作用及可能的机制.方法 采用横断面调查和纵向随访结合的方式,对288名5~16岁健康女性儿童青少年进行连续4年的随访,观察第2性征发育、身高、体重、体脂比例,测定血瘦素和胰岛素样生长因子-1(IGF-1)水平,分析青春发育始动和月经初潮的影响因素.结果 女性儿童青少年血瘦素水平从13岁开始显著增加,至16岁达峰值;IGF-1与青春发育始动年龄相关;体重指数和体脂比例对青春发育始动无显著影响,但与月经初潮年龄呈负相关.结论 体重可能参与了青少年女性月经初潮的发生.  相似文献   

7.
目的:运用骨龄、血清骨钙素指标从骨发育角度对单纯乳房早发育进行分析.方法:对36例单纯乳房早发育女童用TW2法评定骨龄、放射免疫法测定血清骨钙素.结果:本组病例平均年龄7.12±0.61岁,平均骨龄7.58±0.81岁,经统计学处理,t=2.72,P<0.05;血清骨钙素8.91±1.79μg/L,分别与性早熟组及正常值比较,t=14.18、9.7,P均<0.05,差异有显著性意义.结论:运用骨龄、骨钙素等骨发育指标有助于监测单纯乳房早发育.  相似文献   

8.
性发育迟缓     
性发育迟缓是指女孩13岁,男孩14岁尚无青春发育性征的表现.如果开始有青春发育期的性征  相似文献   

9.
杜霞  焦俊 《贵阳医学院学报》2009,34(3):271-275,278
目的:探讨儿童青少年手腕部骨龄标准,了解手腕部骨发育的特点及变化趋势,建立新的骨龄图谱。方法:对健康儿童青少年拍摄左侧手腕部正位X片,采用TW 3法测量手腕部骨龄及百分位表,并与既往标准进行比较。结果:(1)获得新的记分法骨龄标准;(2)新的TW 3标准与TW 2CH(TW 2中国人南方标准)比较,各年龄组R系列骨分值增加,C系列变化不明显;(3)与既往标准比较,7~12岁儿童R系列骨发育提前约0.5岁,C系列提前0.5~1岁,13~18岁青少年变化不明显。结论:R系列受时代影响较大,7~12岁儿童骨发育提前,而13~18岁青少年骨发育变化不明显。  相似文献   

10.
骨龄是指骨骺及小骨(如腕骨)骨化中心出现的年龄及骨干与骨骺联合的年龄。是衡量儿童、青少年生长发育成熟度较准确的指标,也是内分泌疾病诊疗的重要参考指标。影响骨骺发育成熟因素是多方面的,如遗传因素、环境因素、内分泌激素改变,性发育成熟等。2011年11月至2014年7月,因矮身材、性早熟疾病在本月儿科门诊就诊的115名小儿进行骨龄测定,总结如下:1.临床资料:1.1一般资料:115名中,男性44例,女性71例,年龄1-18岁,其中~  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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