尿激酶静脉溶栓治疗老年人急性心肌梗死的临床分析

为了解尿激酶静脉溶栓治疗老年人（≥60岁）急性心肌梗死（AMI）患者的临床疗效和安全性，对我院符合溶栓标准且资料完整的48例AMI患者按年龄段分成＜60岁（18例）和≥60岁（30例）两组，并对其中30例老年AMI患者的近期预后进行分析（以同期未接受溶栓治疗的76例老年AMI患者作为对照组）。结果，年龄＜60岁与≥60岁其溶栓疗效无显著性差异（P＞0．05），但病死率和溶栓副作用有升高趋势；老年溶栓组治疗后主要并发症梗死后心绞痛、再梗塞发生率极显著高于低龄组（P＜0．005或P＜0．01）；老年AMI患者溶栓组的病死率及治疗后主要并发症均显著或非常显著地低于未溶栓组（P＜0．05或P＜0．005）。提示老年（≥60岁）AMI患者静脉溶栓治疗有效，并可显著改善近期预后。     

早期尿激酶静脉溶栓治疗急性心肌梗死24例临床分析

目的 观察早期尿激酶静脉溶栓治疗急性心肌梗死（AMI）的疗效。方法回顾分析24例采用早期尿激酶溶栓治疗与18例采用常规治疗的AMI患者的临床资料，观察溶栓治疗患者的再通情况及溶栓后24h内T波倒置对判断冠脉再通的影响。结果尿激酶治疗组和常规治疗组的冠脉再通率分别为62．5％和15．0％（P〈0．05），发病至开始溶栓的时间越短，再通率越高。结论早期尿激酶静脉溶栓治疗可提高AMI疗效，降低病死率，宜早期应用。     

静脉溶栓治疗糖尿病并发急性心肌梗死的疗效观察

目的：探讨静脉溶栓治疗糖尿病并发急性心肌梗死（AMI）患者的近期疗效。方法：AMI住院病例98例，并发糖尿病35例（糖尿病组），未合并糖尿病63例（非糖尿病组），均在发病后12h内进行尿激酶溶栓治疗，比较两组患者的梗死相关血管再通率及近期疗效。结果：开始溶栓时间糖尿病组平均为（5．68±2．24）h，非糖尿病组平均为（4．66±1．80）h，两组比较，糖尿病组时间延长，有显著性差异（P〈0．05）。溶栓后梗死血管再通率糖尿病组明显低于非糖尿病组（P〈0．05），病死率、再梗死和合并症的发生率均高于非糖尿病组（P〈0．05）。结论：糖尿病并发AMI患者的病情较重，静脉溶栓近期疗效较差，其溶栓治疗再通率较低，这与糖尿病患者开始溶栓时间延迟有关。     

急性心肌梗死心肺复苏术后溶栓的临床研究

目的观察急性心肌梗死（AMI）心肺复苏术后溶栓治疗的有效性和安全性。方法将63例ST段抬高伴心脏骤停心肺复苏成功的AMI患者,根据是否获得溶栓治疗,随机分为溶栓组和对照组。溶栓组31例,对照组32例。两组患者心肺复苏成功后,均给予扩张冠状动脉或抗休克治疗、抗心律失常、脑保护等对症处理,溶栓组给予尿激酶静脉溶栓。结果溶栓纽23例血管再通,对照组4例血管再通,溶栓组患者血管再通率明显高于对照组（P〈0．01）;住院4周平均心脏事件发生率明显低于对照组（P〈0．05）;溶栓组住院4周死亡1例,对照组住院4周死亡9例,病死率明显低于对照组（P〈0．05）;两组患者出血发生率差异无统计学意义（P〉0．05）。结论AMI患者心肺复苏术后行溶栓治疗安全有效。     

早期尿激酶静脉溶栓治疗急性心肌梗死32例临床观察

目的：观察早期尿激酶（UK）静脉溶栓治疗急性心肌梗死（AMI）的疗效。方法：32例AMI患采用早期尿激酶溶栓治疗与55例AMI患的常规治疗对照，观察溶栓治疗的血管再通情况。结果：尿激酶治疗组和对照组的冠脉再通率分别为59．37％和14．55％（P＜0．05），发病至开始溶栓时间越短，再通率越高。结论：早期尿激酶静脉治疗可提高急性心肌梗死疗效。     

急诊科静滴尿激酶治疗急性心肌梗塞17例临床分析

目的：评价急诊科内应用尿激酶（UK）静脉溶栓治疗急性心肌梗塞（AMI）的疗效及安全性。方法：17例（AMI）患者在急诊科接受尿激酶静脉溶栓治疗，尿激酶用量为100－150万u加入NS半小时内滴完。结果：血管再通率为59％，1例并发室颤，1例并发严重窦性心动过缓伴阿－期综合症发作，无严重出血并发症。结论：提示在急诊科应用尿激酶静脉溶栓治疗AMI安全有效。     

急性心肌梗死心跳骤停患者心肺复苏后静脉尿激酶溶栓疗效观察

目的：探讨急性心肌梗死（AMI）心跳骤停患者心肺复苏（CPR）后静脉尿激酶溶栓临床疗效观察。方法：AMI并发呼吸心跳骤停CPR成功患者11例。随机分为治疗组5例,心肺复苏后即刻静脉给予尿激酶150万U,30分内静脉注射;对照组6例,在心肺复苏后予除静脉溶栓外的积极抢救治疗。结果：治疗组的自主循环、自主呼吸恢复例数,24小时存活例数和出院存活例数明显高于对照组,自主循环恢复时间、自主呼吸恢复时间明显短于对照组。结论：AMI患者心肺复苏后进行溶栓治疗,能明显提高患者的自主循环、自主呼吸恢复率、24小时存活率、出院存活率,缩短自主循环、自主呼吸恢复时间,且不增加继发出血发生率。     

急性心肌梗死患者心肺复苏后静脉溶栓临床疗效观察

目的观察急性心肌梗死（AMI）患者心肺复苏后静脉溶栓的临床疗效。方法选取河南科技大学第三附属医院2008年2月至2011年2月入诊的60例急性心肌梗死患者心肺复苏后静脉溶栓（观察组）,与同期60例急性心肌梗死患者心肺复苏后不行静脉溶栓（对照组）临床疗效进行比较,比较两组再通率、病死率及并发症发生率。结果两组比较,观察组并发症发生率（13．3％）明显低于对照组（48．3％）。观察组再通47例,再通率为78．3％;对照组再通11例,再通率18．3％。观察组病死率（8．3％）明显低于对照组（35．0％）,两组比较差异有统计学意义（P〈0．05）。结论急性心肌梗死患者心肺复苏后行静脉溶栓临床疗效明显优于急性心肌梗死患者心肺复苏后不行静脉溶栓治疗。     

尿激酶静脉溶栓治疗急性心肌梗死42例

目的观察尿激酶静脉溶栓治疗急性心肌梗死（AMI）的临床疗效及安全性。方法应用尿激酶静脉溶栓治疗AMI42例，于溶栓后观察再通情况、死亡例数、颅内及其他系统有无并发症。结果溶栓后再通率69．05％，10例出血，5例死亡。结论尿激酶治疗AMI为一种安全、有效的措施。     

天普洛欣静脉溶栓治疗急性心肌梗死92例临床分析

目的：分析天普洛欣静脉溶栓治疗对急性心肌梗死（AMI）患者的疗效与安全性。方法：选择符合静脉溶栓标准的AMI192例患者给予静滴天普洛欣（尿激酶）150万u,并辅以阿斯匹林、肝素及常规治疗,观察冠脉再通及心脏事件发生率、5周死亡率及出血倾向。结果：①冠脉再通62例,其再通率67．4％;②发病至开始溶栓时间＜6h患者,冠脉再通率达81％,＞6h者仅50％（P＜0．005）;③冠脉再通患者的心脏事件发生率为30．65％,5周死亡率为4．84％,而未通患者分别为53．33％和20％（P＜0．025～0．05）;④出现出血倾向10例。结论：天普洛欣静脉溶栓治疗AMI有效且相对安全。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.     

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<正>As culture is the soul of a nation,the three books,"History of Chinese Philosophy,""History of Chinese Culture"and"History of Chinese Science and Technology"have demonstrated the superiority of our great Chinese culture,and its significant impact in the field of international culture.Both core value and practical value of the Chinese culture are very clear,reflected in the views of universe,nature,life,health,disease,and therapy and related considerations,concepts,and technical methods.